利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

19 条记录 (耗时 0.016 秒)

    Lateral flow diagnostic devices with instrument controlled fluidics
    3.
    发明授权
    Lateral flow diagnostic devices with instrument controlled fluidics 有权
    具有仪器控制流体学的侧流诊断装置

    公开(公告)号：US07722817B2

    公开(公告)日：2010-05-25

    申请号：US10649683

    申请日：2003-08-28

    申请人： Imants Lauks ,  Raymond J. Pierce ,  James Wojtyk ,  Benoit R. Bergevin

    发明人： Imants Lauks ,  Raymond J. Pierce ,  James Wojtyk ,  Benoit R. Bergevin

    IPC分类号： B01L3/00

    CPC分类号： B01L3/50273 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2400/0406 ,  B01L2400/0418 ,  F04B19/006 ,  Y10T436/2575

    摘要： Devices with lateral flow elements and integral fluidics are disclosed. The integral fluidics consist of injector pumps comprised of fluidic elements under instrument control. The fluidic element of an injector pump is fluidically connected to lateral flow elements and can be used to control fluid entry into containment chambers referred to as micro-reactors. The lateral flow elements comprise conductor elements that can be used for sample application and transport of analyte contained in the sample to the micro-reactor. Fluidic transport through the fluidic element of the injector pump is under instrument-control. Both the lateral flow element and the fluidic element may contain chemical entities incorporated along their length. The chemical reactions that can be used for analyte detection using the devices are described. Also described are methods of manufacture of these devices.

    摘要翻译： 公开了具有侧向流动元件和整体流体的装置。 积分流体由在仪器控制下由流体元素组成的喷射泵组成。 注射器泵的流体元件流体连接到侧向流动元件，并且可以用于控制流体进入称为微反应器的容纳室中。 横向流动元件包括导体元件，其可以用于将样品中包含的分析物的样品应用和运送到微反应器。 通过注射泵的流体元件的流体传输是在仪器控制下。 侧流元件和流体元件都可以包含沿其长度并入的化学物质。 描述了可用于使用装置进行分析物检测的化学反应。 还描述了这些装置的制造方法。

    Point-of-care in-vitro blood analysis system
    4.
    发明授权
    Point-of-care in-vitro blood analysis system 有权
    点护理体外血液分析系统

    公开(公告)号：US06845327B2

    公开(公告)日：2005-01-18

    申请号：US09875949

    申请日：2001-06-08

    申请人： Imants R. Lauks

    发明人： Imants R. Lauks

    IPC分类号： G01N33/49 ,  G06K17/00 ,  G06K19/00 ,  G01N1/00

    CPC分类号： G01N33/49

    摘要： Devices for cost-effectively performing in-vitro diagnostic chemical analyses at multiple distributed locations within a medical institution are disclosed. One object of this invention is to provide a network of distributed sensory devices that acquire sensor signals from blood specimens and deliver those signals through a connect on to a central location for analysis by a general-purpose computer and generation of an analysis result. The analysis result is then sent to numerous locations on a network for display, including also possibly back to the location of signal acquisition. Cost-effective mobile sensing devices are also disclosed. The present system includes blood-sensor signal acquisition devices distributed throughout the hospital. The sensory signal-acquisition devices are card readers that acquire raw sensory signals from diagnostic cards inserted therein. These diagnostic cards are smart card-like devices modified for blood collection that contain sensory elements such as electrodes adapted to provide a raw sensory signal. The signal acquisition devices are modified smart card readers, which acquire the raw sensory data from an inserted smart card through a standardized contact arrangement and provide the raw data to data processing devices such as data acquisition cards. The system includes multiple remote ports for acquiring blood sensor signals. One or more card reader, when connected to a mobile general-purpose computer, can be converted into a complete mobile blood analyzer.

    摘要翻译： 公开了用于在医疗机构内的多个分布位置进行成本有效地进行体外诊断化学分析的装置。 本发明的一个目的是提供一种分布式感觉器件的网络，其从血液样本中获取传感器信号，并将这些信号通过连接连接到中心位置，以便由通用计算机进行分析并产生分析结果。 然后将分析结果发送到网络上的多个位置进行显示，包括也可能返回到信号采集的位置。 还公开了具有成本效益的移动感测装置。 本系统包括分布在整个医院的血液传感器信号采集装置。 感觉信号采集装置是从插入其中的诊断卡获取原始感觉信号的读卡器。 这些诊断卡是用于血液收集修改的智能卡状设备，其包含感觉元件，例如适于提供原始感觉信号的电极。 信号采集装置是改进的智能卡读卡器，其通过标准化的接触装置从插入的智能卡获取原始感觉数据，并将原始数据提供给数据处理装置，例如数据采集卡。 该系统包括用于采集血液传感器信号的多个远程端口。 一个或多个读卡器连接到移动通用计算机时，可以转换成完整的移动血液分析仪。

    Heterogeneous membrane electrodes
    8.
    发明授权
    Heterogeneous membrane electrodes 有权
    异质膜电极

    公开(公告)号：US07767068B2

    公开(公告)日：2010-08-03

    申请号：US10856929

    申请日：2004-06-01

    申请人： Imants Lauks ,  Anca Varlan ,  Alexandra Oussova ,  Michael Bales

    发明人： Imants Lauks ,  Anca Varlan ,  Alexandra Oussova ,  Michael Bales

    IPC分类号： G01N27/26

    CPC分类号： G01N27/307 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/025 ,  B01L2200/148 ,  B01L2300/0645 ,  B01L2300/0825 ,  B01L2300/0883 ,  B01L2300/0887 ,  B01L2400/0487 ,  B01L2400/0683

    摘要： The present invention relates to planar electrochemical sensors with membrane coatings used to perform chemical analyses. The object of this invention is to provide unit-use disposable sensors of very simple and inexpensive construction, preferably with only a single membrane coating on an electrode. The invented devices are potentiometric salt-bridge reference electrodes and dissolved gas sensors constructed with a heterogeneous membrane coating of a conductor. The heterogeneous membrane, which is an intimate admixture of a hydrophobic and a hydrophilic compartment, concurrently supports constrained transport of non-volatile species through its hydrophilic compartment and rapid gas and water vapor transport through its hydrophobic compartment.

    摘要翻译： 本发明涉及具有用于进行化学分析的膜涂层的平面电化学传感器。 本发明的目的是提供非常简单和便宜的结构的单元使用一次性传感器，优选地在电极上仅具有单个膜涂层。 本发明的器件是电位计的盐桥参考电极和由导体的非均相膜涂层构成的溶解气体传感器。 疏水隔离层和亲水隔室的紧密混合物的非均相膜同时支持非挥发性物质通过其亲水隔室的受限运输，并通过其疏水隔室快速的气体和水蒸汽输送。

    Lateral flow diagnostic devices with instrument controlled fluidics
    9.
    发明授权
    Lateral flow diagnostic devices with instrument controlled fluidics 有权
    具有仪器控制流体学的侧流诊断装置

    公开(公告)号：US08124026B2

    公开(公告)日：2012-02-28

    申请号：US12718139

    申请日：2010-03-05

    申请人： Imants Lauks ,  Raymond J. Pierce ,  James Wojtyk ,  Benoit R. Bergevin

    发明人： Imants Lauks ,  Raymond J. Pierce ,  James Wojtyk ,  Benoit R. Bergevin

    IPC分类号： B01L3/00

    CPC分类号： B01L3/50273 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2400/0406 ,  B01L2400/0418 ,  F04B19/006 ,  Y10T436/2575

    摘要： Devices with lateral flow elements and integral fluidics are disclosed. The integral fluidics consist of injector pumps comprised of fluidic elements under instrument control. The fluidic element of an injector pump is fluidically connected to lateral flow elements and can be used to control fluid entry into containment chambers referred to as micro-reactors. The lateral flow elements comprise conductor elements that can be used for sample application and transport of analyte contained in the sample to the micro-reactor. Fluidic transport through the fluidic element of the injector pump is under instrument-control. Both the lateral flow element and the fluidic element may contain chemical entities incorporated along their length. The chemical reactions that can be used for analyte detection using the devices are described. Also described are methods of manufacture of these devices.

    摘要翻译： 公开了具有侧向流动元件和整体流体的装置。 积分流体由在仪器控制下由流体元素组成的喷射泵组成。 注射器泵的流体元件流体连接到侧向流动元件，并且可以用于控制流体进入称为微反应器的容纳室中。 横向流动元件包括导体元件，其可以用于将样品中包含的分析物的样品应用和运送到微反应器。 通过注射泵的流体元件的流体传输是在仪器控制下。 侧流元件和流体元件都可以包含沿其长度并入的化学物质。 描述了可用于使用装置进行分析物检测的化学反应。 还描述了这些装置的制造方法。