公开(公告)号：US09823185B1

公开(公告)日：2017-11-21

申请号：US15644775

申请日：2017-07-08

Applicant: Airware, Inc.

Inventor： Jacob Y Wong ,  Thomas Campbell

IPC: G01N21/3504

CPC classification number: G01N21/3504 ,  G01J3/10 ,  G01J3/42 ,  G01J3/427 ,  G01N21/3151 ,  G01N21/3577 ,  G01N21/61 ,  G01N33/49 ,  G01N2021/3159 ,  G01N2201/0696

Abstract: For determining concentration of a targeted molecule M in a liquid sample admixed with interfering molecules MJ which overlap its absorption band, a NDIR reflection sampling technique is used. Besides the signal source, a reference and an interference source are added. M is calculated by electronics which use Rave(t) from a pulsed signal and reference channel output and a calibration curve which is validated by use of RJava(t2) from a pulsed interference and reference channel output. Signal, interference and reference sources are pulsed at a frequency which is sufficiently fast so that a given molecule of M or MJ will not pass in and out of the liquid sampling matrix within the pulsing frequency.

公开(公告)号：US07251032B2

公开(公告)日：2007-07-31

申请号：US11185138

申请日：2005-07-20

Applicant: Robert A. Lodder ,  John Carberry

Inventor： Robert A. Lodder ,  John Carberry

IPC: G01N21/25

CPC classification number: G01N21/255 ,  G01N21/31 ,  G01N21/85 ,  G01N2021/3137 ,  G01N2021/3159 ,  G01N2021/3166 ,  G01N2021/317 ,  G01N2201/12746 ,  G01N2201/1293

Abstract: An optical monitoring system for determining the constituents of a sample or specimen. An absorption spectrum is obtained from a sample and is passed through one or more filters having a specified absorption spectrum defined by a single atom or a compound. If the filter's absorption spectrum is included in the sample's absorption spectrum, then the sample contains that atom or compound. The apparatus includes a switching assembly that sequentially places one or more filters into the light path to determine if the subject atom or compound is contained in the sample.

Abstract translation: 用于确定样品或样品的成分的光学监测系统。 从样品中获得吸收光谱，并且通过一个或多个具有由单个原子或化合物限定的特定吸收光谱的滤光片。 如果滤波器的吸收光谱包含在样品的吸收光谱中，则样品中包含该原子或化合物。 该装置包括一个切换组件，其顺序地将一个或多个过滤器放置在光路中以确定样品中是否包含主体原子或化合物。

公开(公告)号：US07113282B2

公开(公告)日：2006-09-26

申请号：US10741237

申请日：2003-12-19

Applicant: Francis M. Aguirre ,  Jack W. Lai

Inventor： Francis M. Aguirre ,  Jack W. Lai

IPC: G01J3/51 ,  G01N21/25

CPC classification number: G01J3/51 ,  G01J1/20 ,  G01J3/0213 ,  G01J3/513 ,  G01N21/31 ,  G01N2021/3133 ,  G01N2021/3159 ,  G01N2021/3166 ,  G01N2021/3174

Abstract: A rotary spectrometer including a plurality of input ports. Each input port may be arranged to receive an optical waveguide carrying electromagnetic radiation. The spectrometer also includes a plurality of optical bandpass filters, which are housed on a first body that rotates under the control of a motor so that each optical bandpass filter may be brought into alignment with each input port. Further, the spectrometer includes a plurality of detector circuits disposed on a second body that rotates with the first body. Each detector circuit is optoelectrically coupled to one of the plurality of optical bandpass filters, thereby resulting in each detector circuit being dedicated to responding to a range of wavelengths determined by the bandpass filter to which it is optoelectrically coupled.

Abstract translation: 一种包括多个输入端口的旋转光谱仪。 每个输入端口可被布置成接收携带电磁辐射的光波导。 光谱仪还包括多个光学带通滤光器，它们容纳在电动机控制下旋转的第一主体上，使得每个光学带通滤波器可以与每个输入端口对齐。 此外，光谱仪包括设置在与第一主体一起旋转的第二主体上的多个检测器电路。 每个检测器电路被光电耦合到多个光带通滤波器中的一个，从而导致每个检测器电路专用于响应由光电耦合到其的带通滤波器确定的波长范围。

公开(公告)号：US3861788A

公开(公告)日：1975-01-21

申请号：US42086373

申请日：1973-12-03

Applicant: NEOTEC CORP

Inventor： WEBSTER DONALD R

IPC: G01J1/18 ,  G01J3/12 ,  G01J3/28 ,  G01N21/31 ,  G01N21/35 ,  G01N33/10 ,  G02B5/28

CPC classification number: G01N33/10 ,  G01J3/12 ,  G01J2001/182 ,  G01J2003/1243 ,  G01J2003/2866 ,  G01N21/314 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/4738 ,  G01N2021/3129 ,  G01N2021/3159 ,  G01N2021/4769 ,  G01N2201/1283

Abstract: An automatic test instrument for gaging the percentage of various constituents in organic substances by comparing the reflective optical density of the subject at various wavelengths. Narrow band optical filters are connected together in the form of a rotatable paddle wheel positioned so that the filters can be individually swept through the incident light path between the specimen and wideband light source. As the filter wheel turns, the band of light passed by each filter is progressively shifted with the changing angle of the filter relative to the light path. The filter wheel configuration includes opaque vanes extending from the ends of the filters to periodically interrupt the passage of light to the specimen. Photocells are positioned to sense the level of light reflected from the specimen. The output of the photocells is sampled at predetermined times relative to the rotation of the filter wheel to yield values indicative of reflected intensity at certain wavelengths. Using these values, an electronic circuit in one embodiment calculates three optical density difference values corresponding to moisture, protein and oil content of the specimen. The difference values are automatically inserted in three linear equations which are solved to obtain readings representing the true percentages of oil, water and protein contained in the specimen. Each time a new specimen is loaded for testing, the instrument is automatically calibrated against a standard sample, preferably Teflon (Trademark). The output of the photocells is amplified in a special circuit which subtracts the level of dark period current from the output when the photocells are illuminated.

Abstract translation: 一种自动测试仪器，用于通过比较不同波长的受试者的反射光密度来测量有机物质中各种成分的百分比。 窄带光学滤波器以可旋转的桨轮的形式连接在一起，其定位成使得滤光器可以被单独扫过样品和宽带光源之间的入射光路。 当滤光轮转动时，每个滤光片通过的光束随着滤光片相对于光路的变化角度逐渐变化。 过滤轮配置包括从过滤器的端部延伸的不透明的叶片，以周期性地中断通向样品的光。 光电池被定位以感测从样品反射的光的水平。 光电池的输出在相对于滤光轮的旋转的预定时间被采样，以产生指示在某些波长处的反射强度的值。 使用这些值，一个实施例中的电子电路计算对应于样品的水分，蛋白质和油含量的三个光密度差值。 差值被自动插入三个线性方程中，这些线性方程被求解以获得表示样品中所含的油，水和蛋白质的真实百分比的读数。 每次加载新的样品进行测试时，仪器将自动根据标准样品进行校准，最好是Teflon（商标）。 光电管的输出在特殊电路中被放大，当光电管被照亮时，其从输出中减去暗周期电流的电平。

公开(公告)号：US20170315051A1

公开(公告)日：2017-11-02

申请号：US15524815

申请日：2015-11-20

Applicant: FUJIKIN INCORPORATED ,  TOHOKU UNIVERSITY

Inventor： Masaaki Nagase ,  Kouji Nishino ,  Nobukazu Ikeda ,  Michio Yamaji ,  Shigetoshi Sugawa ,  Rihito Kuroda

IPC: G01N21/27 ,  G01N21/33 ,  C23C16/18 ,  G01N33/00 ,  C23C16/52

CPC classification number: G01N21/27 ,  C23C16/18 ,  C23C16/52 ,  G01N21/314 ,  G01N21/3151 ,  G01N21/33 ,  G01N33/0027 ,  G01N2021/3155 ,  G01N2021/3159 ,  G01N2021/3181 ,  G01N2201/0627 ,  G01N2201/0696 ,  G01N2201/12 ,  H01L21/205

Abstract: To provide a concentration measurement method with which the concentrations of predetermined chemical components can be measured non-destructively, accurately, and rapidly by a simple means, up to the concentrations in trace amount ranges, as well as a concentration measurement method with which the concentrations of chemical components in a measurement target can be accurately and rapidly measured in real time up to the concentrations in nano-order trace amount ranges, and which is endowed with a versatility that can be realized in a variety of embodiments and modes. In the present invention, a measurement target is irradiated, in a time sharing manner, with light of a first wavelength and light of a second wavelength that have different optical absorption rates with respect to the measurement target. The light of each wavelength, arriving optically via the measurement target as a result of irradiation with the light of each wavelength, is received at a shared light-receiving sensor. A differential signal is formed, the differential signal being of a signal pertaining to the light of the first wavelength and a signal pertaining to the light of the second wavelength, the signals outputted from the light-receiving sensor upon receipt of the light. The concentration of a chemical component in the measurement target is derived on the basis of the differential signal.

公开(公告)号：US5448991A

公开(公告)日：1995-09-12

申请号：US891760

申请日：1992-06-01

Applicant: Michael J. R. Polson ,  Gregory L. Morris

Inventor： Michael J. R. Polson ,  Gregory L. Morris

IPC: A61B5/00 ,  G01N21/31

CPC classification number: A61B5/14551 ,  A61B5/7214 ,  G01N21/3151 ,  A61B5/7207 ,  A61B5/7239 ,  G01N2021/3159 ,  G01N2021/3181 ,  G01N2201/1244

Abstract: An improved pulse oximeter for the measurement of oxygen saturation in the blood, which is faster and more accurate than conventional pulse oximeter. Improved speed and accuracy is attached by elimination of normalization and feedback circuitry and the use of analog to digital converting devices having a wide dynamic range along with a sophisticated computer analysis. The instant invention eliminates inaccuracies resulting from channel matching errors, and detects and eliminates aberrant input data.

Abstract translation: 一种用于测量血液中氧饱和度的改进的脉搏血氧计，其比常规脉搏血氧计更快更准确。 通过消除规范化和反馈电路以及使用具有宽动态范围的模数转换装置以及复杂的计算机分析来提高速度和精度。 本发明消除了由信道匹配误差引起的不准确性，并且检测和消除异常输入数据。

公开(公告)号：US5386295A

公开(公告)日：1995-01-31

申请号：US005321

申请日：1993-01-15

Applicant: Steven C. Switalski ,  David S. Uerz ,  Alan J. Lowne ,  James R. Sandifer ,  Hsue-Yang Liu

Inventor： Steven C. Switalski ,  David S. Uerz ,  Alan J. Lowne ,  James R. Sandifer ,  Hsue-Yang Liu

IPC: G01J1/44 ,  G01J3/08 ,  G01J3/28 ,  G01J3/51 ,  G01N21/31 ,  G01N21/35 ,  G02B26/04 ,  G01J3/02 ,  G01N21/64 ,  G01N21/65

CPC classification number: G01J3/42 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0232 ,  G01J3/0235 ,  G01J3/0289 ,  G01J3/08 ,  G01J3/44 ,  G01N21/314 ,  G02B26/04 ,  G01J2001/4242 ,  G01J2003/1213 ,  G01J2003/2866 ,  G01N2021/3133 ,  G01N2021/3159 ,  G01N2021/3174 ,  G01N2021/4742 ,  G01N21/359 ,  G01N2201/0826 ,  G01N2201/1283

Abstract: A postacquired spectrophotometer, for use with a sample and reference. The spectrophotometer has a filter unit, defining an axis of movement, and pluralities of designated sites and dark sites disposed in uniform relation to the axis. The designated and dark sites are disposed in alternation. Alternating designated sites have apertures and filters covering the apertures. Further, a main member, coaxial with the filter unit, has sample and reference beam paths, which are intersected by the sites. The main member has disposed, in operative relation to the actuators, an actuator sensor, which generates an integration actuator signal upon alignment with each integration actuator and a clamping actuator signal upon alignment with each clamping actuator. Moreover, a drive continuously moves the filter unit relative to the axis and beam paths. Further, a light distribution system directs light separately from the sample and reference to respective beam paths, and then to a detector, which produces a detector signal responsive to light received. Finally, means for processing the signals is provided, including a clamping circuit, integrators, and a demultiplexer.

Abstract translation: 一个采用分光光度计的分光光度计，用于样品和参考。 分光光度计具有限定运动轴线的过滤器单元以及与轴线均匀关系地设置的多个指定位置和暗点。 指定的和黑暗的地点交替处置。 交替指定的位置具有覆盖孔的孔和过滤器。 此外，与过滤器单元同轴的主构件具有与位置相交的样品和参考光束路径。 主构件以致动器的方式相对于致动器设置致动器传感器，其在与每个积分致动器对准时产生积分致动器信号，并且在与每个夹紧致动器对准时产生夹紧致动器信号。 此外，驱动器相对于轴和梁路连续地移动过滤单元。 此外，配光系统将光从样品分开引导并参考各个光束路径，然后引导到检测器，该检测器响应于所接收的光产生检测器信号。 最后，提供用于处理信号的装置，包括钳位电路，积分器和解复用器。

公开(公告)号：US4100412A

公开(公告)日：1978-07-11

申请号：US737106

申请日：1976-10-29

Applicant: Harry H. Hausdorff

Inventor： Harry H. Hausdorff

IPC: G01J3/08 ,  G01J3/12 ,  G01N21/31 ,  G01N21/35 ,  G01N30/62 ,  G01N30/74 ,  G01N21/34

CPC classification number: G01N21/314 ,  G01N21/3504 ,  G01N30/74 ,  G01J2003/1226 ,  G01N2021/3129 ,  G01N2021/3159 ,  G01N2021/6421 ,  G01N2030/628 ,  G01N2030/746 ,  G01N21/35 ,  G01N21/3577

Abstract: An analytical apparatus is described having a non-dispersive, multiwavelength photometric analyzer which is adapted to provide simultaneous display of chromatography peaks at a plurality of different analytical wavelengths. In a particular arrangement, the apparatus includes a chromatograph for separating a sample to be examined into components.

Abstract translation: 描述了一种具有非分散性，多波长光度分析仪的分析装置，其适于提供在多个不同分析波长下同时显示色谱峰。 在具体的布置中，该装置包括用于将要检查的样品分离成组分的色谱仪。

公开(公告)号：US4037970A

公开(公告)日：1977-07-26

申请号：US653848

申请日：1976-01-30

Applicant: Donald R. Webster ,  Eugene R. Ganssle

Inventor： Donald R. Webster ,  Eugene R. Ganssle

IPC: G01J1/18 ,  G01J3/12 ,  G01J3/28 ,  G01N21/31 ,  G01N21/35 ,  G01N33/10 ,  G01J3/48

CPC classification number: G01N21/314 ,  G01N33/10 ,  G01J2001/182 ,  G01J2003/1243 ,  G01J2003/2866 ,  G01N2021/3129 ,  G01N2021/3159 ,  G01N2021/4769 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/4738 ,  G01N2201/1283

Abstract: An automatic test instrument for gaging the percentage of various constituents in organic substances by comparing the reflective optical density of the subject at various wavelengths. Narrow band optical filters are connected together in the form of a rotatable paddle wheel positioned so that the filters can be individually swept through the incident light path between the specimen and wideband light source. As the filter wheel turns, the band of light passed by each filter is progressively shifted with the changing angle of the filter relative to the light path. The filter wheel configuration includes opaque vanes extending from the ends of the filters to periodically interrupt the passage of light to the specimen. Photocells are positioned to sense the level of light reflected from the specimen. The output of the photocells is sampled at predetermined times relative to the rotation of the filter wheel to yield values indicative of reflected intensity at certain wavelengths. Using these values, an electronic circuit in one embodiment calculates three optical density difference values corresponding to moisture, protein and oil content of the specimen. The difference values are automatically inserted in three linear equations which are solved to obtain readings representing the true percentages of oil, water and protein contained in the specimen. Each time a new specimen is loaded for testing, the instrument is automatically calibrated against a standard sample, preferably Teflon (Trademark). The output of the photocells is amplified in a special circuit which subtracts the level of dark period current from the output when the photocells are illuminated.

公开(公告)号：US20170254743A1

公开(公告)日：2017-09-07

申请号：US15504501

申请日：2015-02-23

Applicant: TOHOKU UNIVERSITY

Inventor： Shigetoshi Sugawa ,  Rihito Kuroda

IPC: G01N21/31 ,  A61B5/145 ,  A61B5/1455

CPC classification number: G01N21/31 ,  A61B5/1112 ,  A61B5/1122 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1477 ,  A61B5/4227 ,  A61B5/6898 ,  A61B2505/07 ,  G01N21/031 ,  G01N21/0332 ,  G01N21/3151 ,  G01N21/35 ,  G01N21/3504 ,  G01N2021/158 ,  G01N2021/3159 ,  G01N2021/3181 ,  G01N2201/08

Abstract: To provide a concentration measuring method with which the concentration of a predetermined chemical component can be accurately, quickly, and nondestructively measured down to a concentration range of an extremely small amount with a simple means, and to provide a concentration measuring method with which the concentration of a chemical component in an object to be measured can be accurately and quickly measured down to a concentration range of a nano-order extremely small amount in real time, the method having universality, i.e., the ability to be embodied in various forms and modes. Light having a first wavelength and light having a second wavelength, which have different light absorptances with respect to an object to be measured, are each radiated onto the object to be measured using a time-sharing method; the light having the first wavelength and the light having the second wavelength, optically passing through the object to be measured as a result of the irradiation with the light having the first and second wavelengths, are received with a common light receiving sensor; a differential signal between a signal related to the light having the first wavelength and a signal related to the light having the second wavelength to be output from the light receiving sensor according to the received light is formed; and the concentration of a chemical component in the object to be measured is derived on the basis of the differential signal.