公开(公告)号：EP3218304A1

公开(公告)日：2017-09-20

申请号：EP15808485.5

申请日：2015-11-10

申请人： The Charles Stark Draper Laboratory, Inc.

发明人： CARTER, David J.

IPC分类号： B81C1/00

CPC分类号： C09J7/00 ,  B81C1/00206 ,  B81C2201/0149

摘要： A method of assembly of micro-scale objects includes forming a pattern of a first functional moiety on a surface of a substrate, contacting the surface of the substrate with a first liquid suspension including first micro-scale feedstock elements functionalized with a second functional moiety, complimentary to the first functional moiety, on first portions of the first micro-scale feedstock elements and functionalized with a third functional moiety on second portions of the first micro-scale feedstock elements, aligning the first portions of the first micro-scale feedstock elements with the surface of the substrate, and facilitating bonding the second functional moieties to the first functional moieties to form a first microstructure pattern of the first micro-scale feedstock elements on the surface of the substrate.

摘要翻译： 组装微米尺度物体的方法包括在基材表面上形成第一功能部分的图案，使基材表面与第一液体悬浮液接触，所述第一液体悬浮液包含用第二官能部分官能化的第一微尺度原料元件， 与第一功能部分互补，在第一微尺度原料元件的第一部分上，并且在第一微尺度原料元件的第二部分上用第三功能部分功能化，将第一微尺度原料元件的第一部分与 基材的表面以及促进将第二官能部分键合至第一官能部分以在基材表面上形成第一微尺度原料元件的第一微结构图案。

公开(公告)号：EP3013691A1

公开(公告)日：2016-05-04

申请号：EP14817171.3

申请日：2014-05-16

申请人： The Charles Stark Draper Laboratory, Inc.

发明人： LAINE, Juha-Pekka ,  BLASCHE, Gregory, P. ,  CHAPARALA, Murali, V. ,  DAWSON, Robin ,  LANE, Benjamin ,  SMITH, Stephen, P. ,  WALDRON, Erik

IPC分类号： B64G1/36

CPC分类号： G01S3/7867 ,  G01B9/06 ,  G01B2290/10 ,  G01C21/025 ,  G01S3/785 ,  G02B6/0288 ,  G02B6/122 ,  G02B6/124 ,  G02B6/262 ,  G02B6/34 ,  G02B6/3548 ,  G02B2006/12147

摘要： A chip scale star tracker that captures plane-wave starlight propagating in free space with a wafer-thin angle-sensitive broadband filter-aperture, and directs the light into a waveguide structure for readout. Angular information about the star source is determined from characteristics of the starlight propagating in the waveguide. Certain examples include internal propagation-constant-based baffling to elimination stray light from extreme angles.

公开(公告)号：EP2951282A1

公开(公告)日：2015-12-09

申请号：EP14706712.8

申请日：2014-01-29

申请人： The Charles Stark Draper Laboratory, Inc. ,  Massachusetts Institute of Technology

发明人： CUIFFI, Joseph Dennis ,  MESCHER, Mark Joseph ,  COPPETA, Jonathan Robert ,  INMAN, Samuel Walker ,  SPENCER, Abigail June ,  NGUYEN, Transon Van ,  BORENSTEIN, Jeffrey T.

IPC分类号： C12M3/00 ,  C12M1/32 ,  C12M1/00 ,  C12M1/34

CPC分类号： C12M21/08 ,  C12M23/12 ,  C12M23/44 ,  C12M29/00 ,  C12M29/04 ,  C12M29/12 ,  C12M35/08 ,  C12M41/00 ,  C12M41/12 ,  C12N5/0062 ,  C12N5/0602 ,  C12N5/0697

摘要： The systems and methods disclosed herein are generally related to a cell culture system. More particularly, the systems and methods enable the culturing and interconnecting of a plurality of tissue types in a biomimetic environment. By culturing organ specific tissue types within a biomimetic environment and interconnecting each of the organ systems in a physiologically meaningful way, experiments can be conducted on in vitro cells that substantially mimic the responses of in vivo cell populations. In some implementations, the organ systems are fluidically connected with a constant-volume pump.

公开(公告)号：EP2943282A1

公开(公告)日：2015-11-18

申请号：EP14702676.9

申请日：2014-01-08

申请人： The Charles Stark Draper Laboratory, Inc.

发明人： HARJES, Daniel I. ,  DIBIASIO, Christopher ,  CHAREST, Joseph L. ,  FINLEY, Violet ,  SOONG, Ricky ,  BORENSTEIN, Jeffrey T.

IPC分类号： B01L3/00 ,  A61M1/16

CPC分类号： B81B7/0009 ,  A61M1/16 ,  A61M2205/0244 ,  B01L3/502753 ,  B01L2300/0681 ,  B01L2300/0887 ,  B01L2300/14 ,  B01L2400/086

摘要： A microfluidic device for increasing convective clearance of particles from a liquid is provided. A network of first channels can be separated from a network of second channels by a membrane. The network of second channels can include a pressurizing feature to create a high pressure at an upstream portion of the second channels and a low pressure at a downstream portion of the second channels. Liquid containing an analyte can be introduced in the network of first channels. Filtrate can be flowed through the pressurizing feature in the second channels, such that the pressure difference in between the first and second channels causes at least some of the analyte in the first liquid is transported into the second channels through the membrane.

摘要翻译： 提供了用于提高从液体中的颗粒的对流清除率的微流体装置。 第一信道的网络可以从信道的第二网络通过膜分离。 的第二信道的网络可以包括一个加压特征在所述第二通道的下游部分，以创建在所述第二通道和低压的上游侧部分的高的压力。 含液体的分析物可以第一信道的网络中被引入。 滤液可通过加压特征在所述第二通道中流动，检查在第一和第二通道之间引起至少一些在所述第一液体中的分析物输送到通过膜的第二通道那样的压力差。

公开(公告)号：EP1671378B1

公开(公告)日：2015-04-22

申请号：EP04789300.3

申请日：2004-09-30

申请人： THE CHARLES STARK DRAPER LABORATORY, INC.

发明人： WEINBERG, Marc, S. ,  CUNNINGHAM, Brian ,  HILDEBRANT, Eric

IPC分类号： H01L41/08 ,  G01N29/22 ,  G01N29/02

CPC分类号： G01N29/022 ,  G01L9/0025 ,  G01N2291/0423 ,  G01N2291/0427 ,  Y10T29/42

公开(公告)号：EP2624289A3

公开(公告)日：2014-04-16

申请号：EP13166066.4

申请日：2009-04-03

申请人： The Charles Stark Draper Laboratory, Inc.

发明人： Racz, Livia M. ,  Tepolt, Gary B. ,  Thompson, Jeffrey C. ,  Langdo, Thomas A. ,  Mueller, Andrew J.

IPC分类号： H01L21/68 ,  H01L23/538 ,  H01L25/10 ,  H01L21/60 ,  B81C1/00 ,  H01L23/13 ,  H01L23/498 ,  H01L21/48

CPC分类号： H01L21/486 ,  B81B2207/012 ,  B81C1/00333 ,  B81C2201/019 ,  B81C2201/0191 ,  H01L21/568 ,  H01L21/6835 ,  H01L23/13 ,  H01L23/49827 ,  H01L24/19 ,  H01L24/24 ,  H01L24/82 ,  H01L25/105 ,  H01L2221/68359 ,  H01L2221/68377 ,  H01L2224/04105 ,  H01L2224/24227 ,  H01L2224/73267 ,  H01L2224/8203 ,  H01L2224/92144 ,  H01L2224/9222 ,  H01L2225/1035 ,  H01L2225/1058 ,  H01L2924/01006 ,  H01L2924/01015 ,  H01L2924/01019 ,  H01L2924/01029 ,  H01L2924/01033 ,  H01L2924/01042 ,  H01L2924/01074 ,  H01L2924/01084 ,  H01L2924/014 ,  H01L2924/10329 ,  H01L2924/12042 ,  H01L2924/14 ,  H01L2924/1433 ,  H01L2924/1461 ,  H01L2924/15151 ,  H01L2924/15153 ,  H01L2924/181 ,  H01L2924/18162 ,  H01L2924/19041 ,  H01L2924/19042 ,  H01L2924/19043 ,  Y10T29/49124 ,  H01L2924/00

摘要： An electronic module comprises a substrate having a plurality of cavities. A die is encapsulated within each cavity. A post defines at least a portion of an electrical connection through the substrate.

公开(公告)号：EP2625714A2

公开(公告)日：2013-08-14

申请号：EP11793891.0

申请日：2011-10-06

申请人： The Charles Stark Draper Laboratory, Inc.

发明人： THOMPSON, Jeffrey, C. ,  RACZ, Livia, M. ,  TEPOLT, Gary, B. ,  LANGDO, Thomas, A. ,  MUELLER, Andrew, J.

IPC分类号： H01L23/538 ,  H01L23/13

CPC分类号： H01L23/5389 ,  H01L23/13 ,  H01L2224/73204 ,  H01L2924/09701 ,  H01L2924/1461 ,  H01L2924/15165 ,  H05K1/0281 ,  H05K1/189 ,  H05K3/0067 ,  H05K3/284 ,  H05K2201/10674 ,  H01L2924/15153 ,  H01L2924/00

摘要： In various embodiments, an electronic module features a first cavity in a first side of a substrate, a fill hole extending from the first cavity, and a second cavity in a second side of the substrate. The second cavity is in fluidic communication with the fill hole, and a die is encapsulated within the second cavity.

公开(公告)号：EP1779202B1

公开(公告)日：2011-03-30

申请号：EP05804182.3

申请日：2005-07-13

申请人： THE CHARLES STARK DRAPER LABORATORY, INC.

发明人： MESCHER, Mark, J. ,  VARGHESE,Mathew ,  WEINBERG, Marc, S. ,  MARINIS, Thomas ,  SOUCY, Joseph, W.

IPC分类号： G04F5/14 ,  H01L23/12 ,  H01L23/34

CPC分类号： B81B7/0012 ,  G04F5/14 ,  H01L2924/0002 ,  H01L2924/00

摘要： A suspension of a chip-scale device is accomplished using a suspension frame and at least one first tether. The chip-scale suspension frame defines a first plane and an opening through the suspension frame. At least one first tether crosses the opening at a first angle relative to the first plane and can be used to position the chip-scale device at least partially within the opening.

公开(公告)号：EP2200931A2

公开(公告)日：2010-06-30

申请号：EP08832581.6

申请日：2008-09-19

申请人： The Charles Stark Draper Laboratory, Inc. ,  BRIGHAM & WOMEN'S HOSPITAL

发明人： BORENSTEIN, Jeffrey, T. ,  WEINBERG, Eli, J. ,  HSIAO, James, Ching-ming ,  KHALIL, Ahmad, S. ,  TUPPER, Malinda, M. ,  GARCIA-CARDENA, Guillermo ,  MACK, Peter ,  TAO, Sarah

IPC分类号： B81C5/00 ,  B81C1/00

CPC分类号： B01L3/502707 ,  B01L2200/12 ,  B01L2300/0861 ,  B01L2300/12 ,  B29C33/3857 ,  B29C59/02 ,  B29K2025/06 ,  B29L2031/753 ,  B33Y80/00 ,  B81B2201/058 ,  B81B2203/0338 ,  B81B2203/0376 ,  B81C1/00119 ,  B81C99/0085 ,  Y10T29/49126 ,  Y10T29/49155 ,  Y10T29/49156 ,  Y10T29/49401 ,  Y10T156/1039 ,  Y10T428/139

摘要： Microfluidic structures featuring substantially circular channels may be fabricated by embossing polymer sheets.

摘要翻译： 提供了制造具有基本圆形通道的微流体结构的方法。 所述方法包括（a）提供包括至少一个暴露的导电区域和至少一个暴露的电绝缘区域的图案化晶片; （b）将具有基本上半圆形横截面的反向通道部分电镀到晶片上，从而形成第一主模具; （c）使用第一母模以便在第一聚合物片中压制通道部分; 和（d）将第一聚合物片材与具有对应的通道部分的第二聚合物片材对准和接合，以限定在聚合物片材之间具有基本圆形横截面的第一通道。

公开(公告)号：EP1266214B1

公开(公告)日：2009-09-23

申请号：EP01920576.4

申请日：2001-03-20

申请人： THE CHARLES STARK DRAPER LABORATORY, INC.

发明人： CUNNINGHAM, Brian, T.

IPC分类号： G01N29/02 ,  H01L21/02

CPC分类号： G01N29/022 ,  G01N29/22 ,  G01N2291/02466 ,  G01N2291/0255 ,  G01N2291/0256 ,  G01N2291/0427 ,  G01N2291/106 ,  Y10T29/42 ,  Y10T29/49007

摘要： A method for manufacturing a flexural plate wave sensor includes the steps of depositing an etch-stop layer (34) over a substrate (32), depositing a membrane layer (36) over the etch stop layer, depositing a piezoelectric layer (38) over the membrane layer, forming a first transducer (44) on the piezoelectric layer and forming a second transducer (48) on the piezoelectric layer, spaced from the first transducer. The method further includes the steps of etching a cavity (52) through the substrate, the cavity having substantially parallel interior walls (54a, 54b), removing the portion of the etch stop layer between the cavity and the membrane layer to expose a portion (53) of the membrane layer, and depositing an absorptive coating (56) on the exposed portion of the membrane layer.