中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

90 records (took 0.028 seconds)

    DIVERSE CHEMICAL LIBRARIES BOUND TO SMALL PARTICLES WITH PARAMAGNETIC PROPERTIES
    2.
    发明申请
    DIVERSE CHEMICAL LIBRARIES BOUND TO SMALL PARTICLES WITH PARAMAGNETIC PROPERTIES 审中-公开
    分散化学图书馆附有具有参照性质的小颗粒

    公开(公告)号：US20090247421A1

    公开(公告)日：2009-10-01

    申请号：US12162125

    申请日：2006-03-22

    Applicant: Egisto Boschetti ,  Lee Lomas

    Inventor： Egisto Boschetti ,  Lee Lomas

    IPC: C40B30/04 ,  C40B50/14 ,  C40B40/10 ,  C40B40/04 ,  C40B40/14

    CPC classification number: C07K1/047 ,  G01N33/54326 ,  G01N33/6848

    Abstract: The present invention provides diverse chemical libraries bound to small particle with paramagnetic properties. Typically, the chemical structures comprise a plurality of different chemical moieties, the particles are paramagnetic and have a diameter between about 100 nm and about 10 microns, the chemical structures bound to each particular particle have substantially the same structure and the combinatorial library comprises at least 100,000 different chemical structures.

    Abstract translation: 本发明提供了与具有顺磁性质的小颗粒结合的不同化学文库。 通常，化学结构包括多个不同的化学部分，颗粒是顺磁性的并且具有约100nm至约10微米之间的直径，与每个特定颗粒结合的化学结构具有基本上相同的结构，组合文库至少包含 100,000种不同的化学结构。

    DIVERSE CHEMICAL LIBRARIES BOUND TO SMALL PARTICLES WITH PARAMAGNETIC PROPERTIES
    4.
    发明申请
    DIVERSE CHEMICAL LIBRARIES BOUND TO SMALL PARTICLES WITH PARAMAGNETIC PROPERTIES 审中-公开
    分散化学图书馆附有具有参照性质的小颗粒

    公开(公告)号：US20110111978A1

    公开(公告)日：2011-05-12

    申请号：US13004281

    申请日：2011-01-11

    Applicant: Egisto Boschetti ,  Lee Lomas

    Inventor： Egisto Boschetti ,  Lee Lomas

    IPC: C40B30/04 ,  C40B50/14 ,  B82Y5/00

    CPC classification number: C07K1/047 ,  C07K1/22

    Abstract: The present invention provides diverse chemical libraries bound to small particle with paramagnetic properties. Typically, the chemical structures comprise a plurality of different chemical moieties, the particles are paramagnetic and have a diameter between about 100 nm and about 10 microns, the chemical structures bound to each particular particle have substantially the same structure and the combinatorial library comprises at least 100,000 different chemical structures.

    Abstract translation: 本发明提供了与具有顺磁性质的小颗粒结合的不同化学文库。 通常，化学结构包括多个不同的化学部分，颗粒是顺磁性的并且具有约100nm至约10微米之间的直径，与每个特定颗粒结合的化学结构具有基本上相同的结构，组合文库至少包含 100,000种不同的化学结构。

    Method for purifying proteins
    5.
    发明申请
    Method for purifying proteins 有权
    蛋白质纯化方法

    公开(公告)号：US20060216751A1

    公开(公告)日：2006-09-28

    申请号：US11388181

    申请日：2006-03-22

    Applicant: Egisto Boschetti ,  Lee Lomas

    Inventor： Egisto Boschetti ,  Lee Lomas

    IPC: C40B40/04 ,  C40B40/08 ,  C40B40/10

    CPC classification number: C07K1/047 ,  C07K1/22

    Abstract: The present invention provides methods and kits for purifying a target protein group. The method comprises the steps of contacting a sample comprising at least 95% of the target protein group and at most 5% of contaminating proteins with a library of binding moieties having different binding moieties, binding the contaminating proteins and a minority of the target protein group to the library of binding moieties, separating the unbound target protein group from the proteins bound to the library of binding moieties and collecting the unbound target protein. The collected target protein is more pure than the target protein group in the sample.

    Abstract translation: 本发明提供了用于纯化靶蛋白质组的方法和试剂盒。 该方法包括以下步骤：将包含至少95％的目标蛋白质组和至多5％的污染蛋白质的样品与具有不同结合部分的结合部分的文库结合，结合污染蛋白质和少数靶蛋白质组 到结合部分的文库，将未结合的靶蛋白基团与结合到结合部分文库的蛋白质分离并收集未结合的靶蛋白质。 收集的目标蛋白质比样品中的目标蛋白质组更为纯净。

    Methods of using microspheres for active embolization
    7.
    发明授权
    Methods of using microspheres for active embolization 有权
    微球用于主动栓塞的方法

    公开(公告)号：US08697137B2

    公开(公告)日：2014-04-15

    申请号：US10220982

    申请日：2001-03-23

    Applicant: Jean-Marie Vogel ,  Egisto Boschetti

    Inventor： Jean-Marie Vogel ,  Egisto Boschetti

    IPC: A61K9/50

    CPC classification number: A61K9/1635 ,  A61K31/715 ,  A61K45/06 ,  A61L2430/36 ,  Y10T428/2982

    Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.

    Abstract translation: 本发明涉及包含生物相容的，可溶胀的，基本上亲水的，无毒的和基本上为球形的聚合物材料载体的可注射组合物，其能够有效地输送用于栓塞药物治疗的生物活性治疗因子。 本发明还涉及使用可注射组合物的栓塞基因治疗方法，特别是用于治疗血管生成和非血管生成依赖性疾病的方法。

    FLUIDICS DEVICE
    8.
    发明申请
    FLUIDICS DEVICE 有权
    流体装置

    公开(公告)号：US20120309644A1

    公开(公告)日：2012-12-06

    申请号：US13552356

    申请日：2012-07-18

    Applicant: Lee O. Lomas ,  Jian Ding ,  Egisto Boschetti

    Inventor： Lee O. Lomas ,  Jian Ding ,  Egisto Boschetti

    IPC: C40B30/04 ,  G01N27/447 ,  B01D15/42 ,  F17D1/00

    CPC classification number: G01N30/461 ,  B01D15/325 ,  B01D15/362 ,  B01D15/363 ,  B01L3/5025 ,  B01L3/50255 ,  B01L3/563 ,  B01L2200/026 ,  B01L2200/028 ,  B01L2300/0681 ,  B01L2300/0829 ,  B01L2300/087 ,  B01L2400/0487 ,  C07K1/34 ,  G01N27/44704 ,  G01N27/44795 ,  G01N30/466 ,  G01N30/468 ,  Y10T137/2224 ,  Y10T137/794 ,  Y10T137/86187 ,  Y10T436/255

    Abstract: The present invention contemplates various devices that are configured to separate a sample, which contains more than one unique species, into any desired number of sub-samples by passing the sample across a like number of separation media configured for a first separation protocol. Each of the sub-samples may be further separated by an additional separation protocol, thereby creating a plurality of mini-samples, each of which may be further separated and/or analyzed. The invention also contemplates using a simple method of using conduits to form a fluid path that passes through a plurality of separation media, each of which media is configured to isolate a particular sub-sample. After various sub-samples of the sample are isolated by the various separation media, the conduits may be removed, thereby enabling each of the isolated sub-samples to be further separated and/or analyzed independent of any other sub-sample.

    Abstract translation: 本发明考虑了通过将样品穿过配置用于第一分离方案的相似数量的分离介质，将被配置成将含有多于一种独特物种的样品分离成任何所需数量的子样品的各种装置。 每个子样品可以通过另外的分离方案进一步分离，从而产生多个微型样品，每个小样品可进一步分离和/或分析。 本发明还考虑使用简单的方法来使用导管来形成通过多个分离介质的流体路径，其中每个介质被配置为隔离特定的子样品。 在通过各种分离介质分离样品的各种亚样品之后，可以去除导管，从而使每个分离的子样品能够独立于任何其它亚样品进一步分离和/或分析。

    POLYMER PROBE DOPED WITH CONDUCTIVE MATERIAL FOR MASS SPECTROMETRY
    10.
    发明申请
    POLYMER PROBE DOPED WITH CONDUCTIVE MATERIAL FOR MASS SPECTROMETRY 审中-公开
    聚合物探针与导电材料进行质谱分析

    公开(公告)号：US20080023630A1

    公开(公告)日：2008-01-31

    申请号：US11557286

    申请日：2006-11-07

    Applicant: Egisto Boschetti ,  Lee O. Lomas

    Inventor： Egisto Boschetti ,  Lee O. Lomas

    IPC: H01J49/00

    CPC classification number: H01J49/0418

    Abstract: A mass spectrometer probe is formed of a nonconductive polymer that is doped with conductive material. The probe may be used as, or as part of, a repeller plate in a parallel laser ion desorption/ionization time-of-flight mass spectrometer. Transparent locations on the probe enable a sample placed thereon to be visualized before or during mass spectrometry. The conductive nature of the probe maintains the consistency of the electromagnetic field applied to the sample. The probe also displays low outgassing and high mechanical and chemical stability, thereby enabling it to be used repetitively.

    Abstract translation: 质谱仪探针由掺杂有导电材料的非导电聚合物形成。 探针可以用作平行激光离子解吸/电离飞行时间质谱仪中的或作为排斥板的一部分。 在探针之前或期间，探针上的透明位置使其上放置的样品可视化。 探头的导电性质保持了施加到样品的电磁场的一致性。 该探头还显示出低的除气和高的机械和化学稳定性，从而使其能够重复使用。

Patent Agency Ranking