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公开(公告)号：US08746369B2
公开(公告)日：2014-06-10
申请号：US13200802
申请日：2011-09-30
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Nathan P. Myhrvold , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Nathan P. Myhrvold , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
摘要： Exemplary methods, systems and components disclosed herein provide propagation of light signals from an external source to a borehole mining mole which includes an optical/electric transducer configured to provide propulsive power for the borehole mining mole and its associated mineral prospecting tools. Some embodiments include one or more umbilicals connected from a remote source location to an onboard reel incorporated with the borehole mining mole. The umbilicals are spooled outwardly or inwardly from the onboard reel during traverse of the borehole mining mole along a path in an earthen environment.
摘要翻译： 本文公开的示例性方法，系统和组件提供了光信号从外部源到钻孔开采的传播，其包括配置成为钻孔开采痣及其相关矿物探矿工具提供推进力的光/电换能器。 一些实施例包括从远程源位置连接到与井眼开采痣相结合的车载卷轴的一个或多个脐带。 沿着沿着土壤环境中的路径横穿钻孔采矿痣时，脐带从船上卷轴向外或向内缠绕。
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公开(公告)号：US20130165148A1
公开(公告)日：2013-06-27
申请号：US13336979
申请日：2011-12-23
申请人： Paramvir Bahl , Douglas C. Burger , Ranveer Chandra , Matthew G. Dyor , William Gates , Roderick A. Hyde , Pablos Holman , Muriel Y. Ishikawa , Jordin T. Kare , Royce A. Levien , Richard T. Lord , Robert W. Lord , Mark A. Malamud , Craig J. Mundie , Nathan P. Myhrvold , Tim Paek , John D. Rinaldo, JR. , Desney S. Tan , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y. H. Wood , Lin Zhong
发明人： Paramvir Bahl , Douglas C. Burger , Ranveer Chandra , Matthew G. Dyor , William Gates , Roderick A. Hyde , Pablos Holman , Muriel Y. Ishikawa , Jordin T. Kare , Royce A. Levien , Richard T. Lord , Robert W. Lord , Mark A. Malamud , Craig J. Mundie , Nathan P. Myhrvold , Tim Paek , John D. Rinaldo, JR. , Desney S. Tan , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y. H. Wood , Lin Zhong
IPC分类号： H04W24/00
CPC分类号： H04W52/0264 , G01S5/0027 , G01S5/0205 , G06F21/88 , G06F2221/2111 , Y02D70/00 , Y02D70/142 , Y02D70/144 , Y02D70/164 , Y02D70/23
摘要： Systems and methods are described relating to accepting a mobile device location query using digital signal processing and presenting an indication of location of the mobile device at least partially based on receiving the location query. Additionally, systems and methods are described relating to means for accepting a mobile device location query using digital signal processing and means for presenting an indication of location of the mobile device at least partially based on receiving the location query.
摘要翻译： 描述了关于使用数字信号处理接受移动设备位置查询并且至少部分地基于接收位置查询来呈现移动设备的位置的指示的系统和方法。 另外，描述了关于使用数字信号处理接受移动设备位置查询的装置和用于至少部分基于接收位置查询来呈现移动设备的位置的指示的装置的系统和方法。
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93.发明授权公开(公告)号：US09457666B2
公开(公告)日：2016-10-04
申请号：US13436316
申请日：2012-03-30
申请人： Kenneth G. Caldeira , Alistair K. Chan , Daniel B. Cook , William David Duncan , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , John Latham , Stephen H. Salter , Clarence T. Tegreene , David B. Tuckerman , Thomas A. Weaver , Charles Whitmer , Victoria Y. H. Wood , Lowell L. Wood, Jr.
发明人： Kenneth G. Caldeira , Alistair K. Chan , Daniel B. Cook , William David Duncan , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , John Latham , Stephen H. Salter , Clarence T. Tegreene , David B. Tuckerman , Thomas A. Weaver , Charles Whitmer , Victoria Y. H. Wood , Lowell L. Wood, Jr.
CPC分类号： B60L11/1809 , B60D1/64 , B60L3/0046 , B60L7/18 , B60L11/123 , B60L11/126 , B60L11/14 , B60L11/1816 , B60L11/1861 , B60L11/1864 , B60L2200/12 , B60L2200/18 , B60L2200/26 , B60L2200/28 , B60L2200/40 , B60L2240/545 , B60L2240/622 , B60L2250/16 , B60L2270/40 , B60Y2200/91 , B60Y2200/92 , H02J7/0054 , Y02P90/60 , Y02T10/6217 , Y02T10/7005 , Y02T10/7044 , Y02T10/7061 , Y02T10/7072 , Y02T10/7077 , Y02T10/7291 , Y02T90/14 , Y02T90/16 , Y02T90/162 , Y10S903/903
摘要： The present invention may include a towable trailer being mechanically couplable to a vehicle, the towable trailer including an auxiliary battery housing unit, a wheel being rotatably connected to the towable trailer, an auxiliary battery disposed within the auxiliary battery housing unit of the towable trailer, the vehicle including a storage battery, the auxiliary battery of the towable trailer being electrically couplable with the storage battery of the vehicle via a bidirectional pathway, and a control system configured to control a transfer of electrical energy between the auxiliary battery of the towable trailer and the storage battery of the vehicle along the bidirectional pathway.
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公开(公告)号：US08211656B2
公开(公告)日：2012-07-03
申请号：US12228880
申请日：2008-08-13
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , William Gates , Alois A. Langer , Eric C. Leuthardt , Royce A. Levien , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , William Gates , Alois A. Langer , Eric C. Leuthardt , Royce A. Levien , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC分类号： G01N33/555 , A61K31/00
摘要： Modified red blood cells are described. In an embodiment, the modified red blood cell includes a target-binding agent. Targeted delivery of imaging agents, drugs, and peptide and protein pharmaceuticals using modified red blood cells are described. Processes for preparing the modified red blood cells, pharmaceutical and diagnostic compositions containing the same and methods of diagnosis and treatment involving the modified red blood cells are described.
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95.发明授权Method and apparatus for supplying auxiliary electrical power to an electric or hybrid vehicle 有权向电动或混合动力汽车提供辅助电力的方法和装置公开(公告)号：US09321357B2
公开(公告)日：2016-04-26
申请号：US13436290
申请日：2012-03-30
申请人： Kenneth G. Caldeira , Alistair K. Chan , Daniel B. Cook , William David Duncan , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , John Latham , Stephen H. Salter , Clarence T. Tegreene , David B. Tuckerman , Thomas A. Weaver , Charles Whitmer , Victoria Y. H. Wood , Lowell L. Wood, Jr.
发明人： Kenneth G. Caldeira , Alistair K. Chan , Daniel B. Cook , William David Duncan , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , John Latham , Stephen H. Salter , Clarence T. Tegreene , David B. Tuckerman , Thomas A. Weaver , Charles Whitmer , Victoria Y. H. Wood , Lowell L. Wood, Jr.
CPC分类号： B60L11/1801 , B60L11/18 , B60L11/1868 , B60L2200/12 , B60L2200/26 , B60L2200/28 , B60L2200/40 , H02J7/0054 , Y02P90/60 , Y02T10/7005 , Y02T10/7066
摘要： The present invention may include a towable trailer being mechanically couplable to a vehicle, the towable trailer including an auxiliary battery housing unit, a wheel being rotatably connected to the towable trailer, an auxiliary battery disposed within the auxiliary battery housing unit of the towable trailer, the vehicle including a storage battery, the auxiliary battery of the towable trailer being electrically couplable with the storage battery of the vehicle via a bidirectional pathway, and a control system configured to control a transfer of electrical energy between the auxiliary battery of the towable trailer and the storage battery of the vehicle along the bidirectional pathway.
摘要翻译： 本发明可以包括可车辆连接的拖车拖车，该牵引拖车包括一个辅助蓄电池壳体单元，一个可转动地连接到该拖车上的轮子，一个设置在该拖车拖车的辅助蓄电池容纳单元内的辅助蓄电池， 所述车辆包括蓄电池，所述拖曳拖车的辅助电池经由双向路径与所述车辆的蓄电池电耦合;以及控制系统，被配置为控制所述可拖曳拖车的辅助电池和 车辆的蓄电池沿着双向路径。
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96.发明申请Compton scattered X-ray visualization, imaging, or information provider using image combining 审中-公开康普顿散射X射线可视化，成像或信息提供者使用图像组合公开(公告)号：US20080253627A1
公开(公告)日：2008-10-16
申请号：US11786739
申请日：2007-04-11
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Robert W. Lord , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood , Victoria Y. H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Robert W. Lord , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood , Victoria Y. H. Wood
IPC分类号： G06K9/36
CPC分类号： A61B6/483 , A61B6/12 , A61B6/145 , A61B6/482 , A61B6/505 , A61B6/506 , A61B6/507 , A61B6/508 , A61B6/548 , A61B18/12 , A61B18/20 , A61N7/02
摘要： One aspect relates to deriving at least one first visualization, image, or provided information via Compton scattering substantially within an at least some matter of an at least a portion of an individual at least partially as a result of directing an at least one first applied X-ray having an at least one first energy level towards the at least some matter of the at least the portion of the individual; deriving at least one second visualization, image, or provided information via Compton scattering substantially within the at least some matter of the at least the portion of the individual at least partially as a result of directing an at least one second applied X-ray having an at least one second energy level toward the at least some matter of the at least the portion of the individual; and deriving at least one combined visualization, combined image, or combined provided information at least partially by combining the at least one first visualization, image, or provided information with the at least one second visualization, image, or provided information.
摘要翻译： 一方面涉及至少部分地通过引导至少一个第一施加的X的结果，在至少部分个人的至少一部分内基本上经由康普顿散射来导出至少一个第一可视化，图像或提供的信息 射线具有朝向个体的至少一部分的至少一些物质的至少一个第一能级; 通过至少部分地至少部分地导致至少一个第二施加的X射线的结果，至少部分地通过基本上在所述个体的至少一部分的至少一些物质内的康普顿散射得到至少一个第二可视化，图像或提供的信息， 至少一个第二能量水平朝向所述至少所述个体的所述部分的所述至少一些物质; 以及至少部分地通过将所述至少一个第一可视化，图像或提供的信息与所述至少一个第二可视化，图像或提供的信息组合来得出至少一个组合的可视化，组合的图像或组合的提供的信息。
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97.发明申请Compton scattered X-ray visualization, imaging, or information provider with time of flight computation 有权康普顿分散的X射线可视化，成像或信息提供者与飞行时间计算公开(公告)号：US20080253521A1
公开(公告)日：2008-10-16
申请号：US11786759
申请日：2007-04-11
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Robert W. Lord , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood , Victoria Y. H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Robert W. Lord , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood , Victoria Y. H. Wood
IPC分类号： G01N23/201
CPC分类号： A61B6/483 , A61B6/12 , A61B6/145 , A61B6/482 , A61B6/505 , A61B6/506 , A61B6/507 , A61B6/508 , A61B6/548 , A61B18/12 , A61B18/20 , A61N7/02
摘要： One aspect relates to locating an at least one scattering event at least partially within an at least some matter of an at least a portion of an individual at least partially by directing an at least one pulse-type applied X-ray at the at least some matter of the at least the portion of the individual to create an at least one corresponding pulse-type Compton scattered X-ray, wherein the locating the at least one scattering event is based at least in part on an at least one time of flight computation derived at least in part from a combination of an at least one applied duration and an at least one scattered duration, wherein the at least one applied duration corresponds to a time for the at least one pulse-type applied X-ray to reach the at least one scattering event within the at least some matter of the at least the portion of the individual, and further wherein the at least one scattered duration corresponds to a time for the at least one corresponding pulse-type Compton scattered X-ray to thereupon travel from the at least one scattering event within the at least some matter of the at least the portion of the individual to be detected.
摘要翻译： 一个方面涉及至少部分地至少部分地至少部分地位于个体的至少一部分内的至少一个散射事件，至少部分地通过将至少一个脉冲型施加的X射线引导到至少一些 该个体的至少一部分的物质以产生至少一个对应的脉冲型康普顿散射X射线，其中定位该至少一个散射事件至少部分地基于至少一次飞行时间计算 至少部分地来自至少一个施加持续时间和至少一个散射持续时间的组合，其中所述至少一个施加的持续时间对应于所述至少一个脉冲型施加的X射线到达所述时间的时间 在所述个体的至少一部分的至少一些物质内的至少一个散射事件，并且其中所述至少一个散射持续时间对应于所述至少一个对应的脉冲型康普顿散射的时间 X射线随后从至少一个待检测个体的该部分的至少一些物质内的至少一个散射事件行进。
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公开(公告)号：US09198563B2
公开(公告)日：2015-12-01
申请号：US13136679
申请日：2011-08-05
申请人： Bran Ferren , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, Jr. , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Bran Ferren , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, Jr. , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61B5/145 , A61B6/00 , A61B5/00 , A61B10/00 , A61M25/098 , A61M5/00 , A61B1/04 , A61B5/06 , A61B5/07 , A61B5/08 , A61B10/04 , A61B18/20 , A61B5/02 , A61B5/0215 , A61B5/026 , A61B5/03 , A61B7/00 , A61B17/22 , A61B10/02 , A61B17/00 , A61B19/00 , A61F2/82 , A61N1/40 , A61N7/00
CPC分类号： A61B1/041 , A61B1/00156 , A61B5/0022 , A61B5/0031 , A61B5/0071 , A61B5/01 , A61B5/02007 , A61B5/0215 , A61B5/026 , A61B5/03 , A61B5/062 , A61B5/07 , A61B5/073 , A61B5/076 , A61B5/082 , A61B5/14539 , A61B5/14546 , A61B5/4064 , A61B5/411 , A61B5/418 , A61B5/4839 , A61B5/6852 , A61B7/00 , A61B10/0045 , A61B10/04 , A61B17/22 , A61B17/22012 , A61B18/20 , A61B34/73 , A61B2010/0077 , A61B2010/0225 , A61B2017/00022 , A61B2017/00345 , A61F2/82 , A61N1/406 , A61N7/00 , G06F19/00 , G16H40/67
摘要： Methods of controlling the operation of a device traveling in a body tube tree, including determining a time based on a signal from a timing device and performing an action based on the determined time, implemented with a control system located partially or fully on the lumen traveling device. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described.
摘要翻译： 控制在体管树中行进的装置的操作的方法，包括基于来自定时装置的信号确定时间并基于所确定的时间执行动作，该控制系统部分地或完全地位于流明行进 设备。 可以通过该设备执行各种动作，例如医疗或治疗目的。 还描述了包括用于执行方法的指令的机器可读介质。
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公开(公告)号：US09187330B2
公开(公告)日：2015-11-17
申请号：US12283908
申请日：2008-09-15
申请人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC分类号： C07K16/32 , A61K38/1703 , A61K38/1732 , A61K47/60 , A61K47/6871 , A61K47/6901 , B82Y5/00 , B82Y15/00 , B82Y30/00 , B82Y40/00 , C01B21/0648 , C01B32/168 , C01B32/174 , C01B2202/02 , C01B2202/34 , C01B2202/36 , C01P2004/13 , Y02A50/473 , Y10S977/743 , Y10S977/75 , Y10S977/762 , Y10S977/788 , Y10S977/795 , Y10S977/848 , Y10S977/896 , Y10S977/915
摘要： Devices, compositions, and methods are described which provide a tubular nanostructure targeted to a lipid bilayer membrane. The targeted tubular nanostructure can have a surface region configured to pass through a lipid bilayer membrane of a cell, a hydrophobic surface region flanked by two hydrophilic surface regions configured to form a pore in a lipid bilayer membrane of a cellular organelle, and at least one ligand configured to bind one or more cognates on the lipid bilayer membrane of the cellular organelle. The target cell can be, for example, a tumor cell, an infected cell, or a diseased cell in a subject. The tubular nanostructure can form a pore in the lipid bilayer membrane of the cellular organelle, e.g., mitochondria, which can permit transit or translocation of at least one compound across the membrane and cause cell death of the target cell.
摘要翻译： 描述了提供靶向脂质双层膜的管状纳米结构的装置，组合物和方法。 目标管状纳米结构可以具有被配置为穿过细胞的脂质双层膜的表面区域，侧壁有两个亲水性表面区域的疏水性表面区域，所述疏水性表面区域配置成在细胞器官细胞器的脂质双层膜中形成孔，以及至少一个 配体被配置为结合细胞器的脂质双层膜上的一个或多个同源物。 靶细胞可以是例如受试者中的肿瘤细胞，感染细胞或患病细胞。 管状纳米结构可以在细胞器（例如线粒体）的脂质双层膜中形成孔，其可以允许至少一种化合物跨过膜的转运或易位并导致靶细胞的细胞死亡。
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公开(公告)号：US09011329B2
公开(公告)日：2015-04-21
申请号：US11403230
申请日：2006-04-12
申请人： Bran Ferren , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , Richa Wilson , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Bran Ferren , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , Richa Wilson , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61B5/00 , A61B18/20 , A61B5/07 , A61B5/145 , A61B10/00 , A61B10/04 , A61B17/22 , A61B5/08 , A61B5/0215 , A61B5/026 , A61B5/03 , A61B7/00 , A61B10/02 , A61B17/00 , A61B19/00 , A61F2/82 , A61N1/40 , A61N7/00
CPC分类号： A61B18/20 , A61B5/0002 , A61B5/0215 , A61B5/026 , A61B5/03 , A61B5/076 , A61B5/14539 , A61B5/14546 , A61B5/411 , A61B5/418 , A61B7/00 , A61B10/0045 , A61B10/04 , A61B17/22 , A61B17/22012 , A61B34/73 , A61B2010/0077 , A61B2010/0225 , A61B2017/00022 , A61B2017/00345 , A61F2/82 , A61N1/406 , A61N7/00
摘要： Embodiments of a lumenally-active system and method of use and control thereof are disclosed. According to various embodiments, a lumenally-active device is positioned in a body lumen of an organism, where the device may sense a parameter of a fluid in the body lumen and perform an action on the fluid. Control logic and/or circuitry may be located on the device, or the system may include a separate control module. Liquid or gaseous fluids may be treated by embodiments of the device. Actions may include, for example, modification of a body fluid by addition or removal of a material, or by modification of a property of a body fluid or a component thereof.
摘要翻译： 公开了一种管腔活动系统及其使用和控制方法的实施例。 根据各种实施例，管腔活动装置定位在生物体的体腔中，其中装置可以感测体腔内的流体的参数并对流体执行作用。 控制逻辑和/或电路可以位于设备上，或者系统可以包括单独的控制模块。 液体或气体流体可以通过该装置的实施方案来处理。 动作可以包括例如通过添加或去除材料来修饰体液，或通过改变体液或其组分的性质来改变体液。
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