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    SAMPLE PROCESSING DROPLET ACTUATOR, SYSTEM AND METHOD
    103.
    发明申请
    SAMPLE PROCESSING DROPLET ACTUATOR, SYSTEM AND METHOD 审中-公开
    样品加工滴剂致动器，系统和方法

    公开(公告)号：US20150072900A1

    公开(公告)日：2015-03-12

    申请号：US14498378

    申请日：2014-09-26

    Applicant: ADVANCED LIQUID LOGIC, INC. ,  DUKE UNIVERSITY

    Inventor： Vijay Srinivasan ,  Vamsee K. Pamula ,  Michael G. Pollack

    IPC: B01L3/00 ,  B01J19/00

    CPC classification number: B01L3/502784 ,  B01J19/0046 ,  B01J2219/00466 ,  B01J2219/00495 ,  B01J2219/00587 ,  B01J2219/00725 ,  B01L3/502761 ,  B01L2200/0642 ,  B01L2200/0647 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/0864 ,  B01L2300/0887 ,  B01L2300/0893 ,  B01L2300/18 ,  B01L2400/0427 ,  B01L2400/043 ,  C07K1/1136 ,  C30B7/00 ,  C30B29/58 ,  Y10T436/2575

    Abstract: Sample processing droplet actuators, systems and methods are provided. According to one embodiment, a stamping device including a droplet microactuator is provided and includes: (a) a first plate including a path or network of control electrodes for transporting droplets on a surface thereof; (b) a second plate mounted in a substantially parallel orientation with respect to the first plate providing an interior volume between the plates, the second plate including one or more stamping ports for transporting some portion or all of a droplet from the interior volume to an exterior location; (c) a port for introducing fluid into the interior volume between the plates; and (d) a path or network of reference electrodes corresponding to the path or network of control electrodes. Associated systems and methods including the stamping device are also provided.

    Abstract translation: 提供样品处理液滴致动器，系统和方法。 根据一个实施例，提供了一种包括液滴微致动器的冲压装置，其包括：（a）包括用于在其表面上输送液滴的控制电极的路径或网络的第一板; （b）相对于第一板以基本上平行的方向安装的第二板，提供板之间的内部容积，第二板包括一个或多个冲压端口，用于将一些部分或全部液滴从内部容积输送到 外部位置; （c）用于将流体引入板之间的内部容积的端口; 和（d）对应于控制电极的路径或网络的参考电极的路径或网络。 还提供了包括冲压装置在内的相关系统和方法。

    METHODS OF MAINTAINING DROPLET TRANSPORT
    105.
    发明申请
    METHODS OF MAINTAINING DROPLET TRANSPORT 审中-公开
    维护运输的方法

    公开(公告)号：US20150021182A1

    公开(公告)日：2015-01-22

    申请号：US14337903

    申请日：2014-07-22

    Applicant: ADVANCED LIQUID LOGIC, INC.

    Inventor： ARNAUD RIVAL ,  CYRIL DELATTRE

    IPC: B01L3/02 ,  B01L3/00

    CPC classification number: B01L3/502792 ,  B01L3/50273 ,  B01L2200/143 ,  B01L2400/0427 ,  F04B19/006

    Abstract: The invention provides a method for reducing or preventing droplet pinning as the droplet is transported across a boundary between a ground electrode region and a non-ground electrode region on a droplet actuator. The invention also provides a method for reducing or preventing droplet super-movement as the droplet is transported across a boundary between a ground electrode region and a non-ground electrode region on a droplet actuator.

    Abstract translation: 本发明提供了一种在液滴通过液滴致动器上的接地电极区域和非接地电极区域之间的边界输送时减少或防止液滴钉扎的方法。 本发明还提供了一种当液滴通过液滴致动器上的接地电极区域和非接地电极区域之间的边界输送时减少或防止液滴超移动的方法。

    Capacitance Detection in a Droplet Actuator
    107.
    发明申请
    Capacitance Detection in a Droplet Actuator 有权
    滴液致动器中的电容检测

    公开(公告)号：US20140332380A1

    公开(公告)日：2014-11-13

    申请号：US14338889

    申请日：2014-07-23

    Applicant: Advanced Liquid Logic, Inc.

    Inventor： Ryan A. Sturmer ,  Michael G. Pollack ,  Vamsee K. Pamula ,  Vijay Srinivasan ,  Philip Y. Paik

    IPC: B01L3/00

    CPC classification number: B01L3/50273 ,  B01L3/502715 ,  B01L3/502784 ,  B01L2200/0605 ,  B01L2300/0627 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0809 ,  B01L2400/0427 ,  G01N27/22 ,  G01N27/223 ,  G01N27/227 ,  G01N2203/00 ,  G01V3/02

    Abstract: A method, circuit and apparatus for detecting capacitance on a droplet actuator, inter alia, for determining the presence, partial presence or absence of a droplet at an electrode on a droplet actuator by: (a) providing a droplet actuator comprising: (i) a substrate comprising electrodes arranged on the substrate for conducting droplet operations on a surface of the substrate; (ii) a capacitance detection circuit for detecting capacitance at the droplet operations surface at one or more of the electrodes; (b) detecting capacitance at the droplet operations surface at one or more of the electrodes; and (c) determining from the capacitance the presence, partial presence or absence of a droplet at the droplet operations surface at the electrode.

    Abstract translation: 一种用于检测液滴致动器上电容的方法，电路和装置，特别是用于通过以下步骤确定液滴致动器上的电极处的液滴的存在，部分存在或不存在：（a）提供液滴致动器，其包括：（i） 基板，其包括布置在所述基板上的电极，用于在所述基板的表面上进行液滴操作; （ii）电容检测电路，用于检测一个或多个电极处的液滴操作表面处的电容; （b）在一个或多个电极处检测液滴操作表面处的电容; 和（c）根据电容确定在电极处的液滴操作表面处的液滴的存在，部分存在或不存在。

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