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    Apparatus for applying a plurality of electro-magnetic radiations to a sample
    125.
    发明授权
    Apparatus for applying a plurality of electro-magnetic radiations to a sample 有权
    用于将多个电磁辐射施加到样品的装置

    公开(公告)号：US09186066B2

    公开(公告)日：2015-11-17

    申请号：US11670027

    申请日：2007-02-01

    申请人： Guillermo J. Tearney ,  Milen Shishkov ,  Brett Eugene Bouma ,  Benjamin J. Vakoc

    发明人： Guillermo J. Tearney ,  Milen Shishkov ,  Brett Eugene Bouma ,  Benjamin J. Vakoc

    IPC分类号： A61B18/18 ,  A61B5/00 ,  A61B18/24 ,  A61B17/00 ,  A61B17/22 ,  A61B18/20 ,  A61B19/00

    CPC分类号： A61B5/0084 ,  A61B5/0066 ,  A61B5/6852 ,  A61B18/24 ,  A61B2017/00057 ,  A61B2017/22051 ,  A61B2018/207 ,  A61B2090/306 ,  A61B2090/3614

    摘要： An apparatus for applying a plurality of electro-magnetic radiations to a sample is provided. In one exemplary embodiment, the apparatus can include an arrangement which has a specific portion with a plurality of channels. One of channels can facilitate a first radiation of the radiations to be forwarded to the sample that is within an anatomical structure, and another one of the channels can facilitate a second radiation of the radiations to be forwarded to the sample. The first radiation may have a first wavelength band, and the second radiation may have a second wavelength band. The first wavelength band may be substantially different from the second wavelength band. According to another exemplary embodiment, the first radiation can be adapted to be delivered to a first area of the sample, and the second radiation may be capable of being delivered to a second area of the sample. The first area may be substantially enclosed by the second area. According to yet another exemplary embodiment of the present invention, each of the channels can facilitate at least one particular radiation of the radiations to be forwarded to the sample that is within an anatomical structure of the sample, the radiations being delivered to different areas of the sample. Centers of every one of the areas may be provided substantially along a line.

    摘要翻译： 提供了一种向样品施加多个电磁辐射的装置。 在一个示例性实施例中，装置可以包括具有多个通道的特定部分的装置。 通道中的一个可以促进要转发到解剖结构内的样品的辐射的第一辐射，并且另一个通道可以促进辐射的第二次辐射以被转发到样品。 第一辐射可以具有第一波长带，并且第二辐射可以具有第二波长带。 第一波长带可能与第二波长带显着不同。 根据另一示例性实施例，第一辐射可以适于被传送到样品的第一区域，并且第二辐射可以能够被传送到样品的第二区域。 第一区域可以基本上被第二区域包围。 根据本发明的另一个示例性实施例，每个通道可以促进辐射的至少一个特定辐射被转发到样品的解剖结构内的样品，辐射被递送到样品的解剖结构中 样品。 可以基本沿着一条线提供每个区域的中心。

    METHODS AND SYSTEMS FOR OPTICAL IMAGING OR EPITHELIAL LUMINAL ORGANS BY BEAM SCANNING THEREOF
    126.
    发明申请
    METHODS AND SYSTEMS FOR OPTICAL IMAGING OR EPITHELIAL LUMINAL ORGANS BY BEAM SCANNING THEREOF 有权
    通过光束扫描对光学成像或上传光学仪器的方法和系统

    公开(公告)号：US20140301620A1

    公开(公告)日：2014-10-09

    申请号：US14243508

    申请日：2014-04-02

    申请人： Guillermo J. Tearney ,  Milen Shishkov ,  Brett Eugene Bouma ,  Benjamin J. Vakoc ,  Norman S. Nishioka

    发明人： Guillermo J. Tearney ,  Milen Shishkov ,  Brett Eugene Bouma ,  Benjamin J. Vakoc ,  Norman S. Nishioka

    IPC分类号： G06T7/00

    CPC分类号： A61B5/0084 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0068 ,  A61B5/6852 ,  A61B5/7271 ,  G06T7/0012 ,  G06T2207/10056 ,  G06T2207/10101

    摘要： Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through. Another arrangement can be provided which is configured to measure a pressure within the at least one portion. The data may include a position and/or an orientation of the first arrangement with respect to the luminal or hollow sample.

    摘要翻译： 提供了布置，装置，系统和系统以获得至少一个管腔或中空样品中的至少一个部分的数据。 该装置，系统或装置可以（可通过患者的嘴部或鼻子中的至少一个插入），例如，第一光学装置可以被配置为收发至少一个电磁（例如，可见） 第二布置可以至少部分地包围第一布置。此外，第三布置可被配置为被致动以将第一布置定位在管腔或中空样品内的预定位置处，第一布置可以是 被配置为补偿由第二布置和/或第三布置引起的至少一个像差（例如，散光），第二布置可以包括使引导布置能够插入到其中的至少一个部分，可以提供另一种布置 其被配置为测量所述至少一个部分内的压力，所述数据可以包括所述第一装置的位置和/或取向与r 对于管腔或空心样品。

    Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion(s)
    127.
    发明授权
    Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion(s) 有权
    用于获得和提供与样品的至少一部分相关联的成像信息并实现这样的部分的装置和方法，

    公开(公告)号：US08838213B2

    公开(公告)日：2014-09-16

    申请号：US11875676

    申请日：2007-10-19

    申请人： Guillermo J. Tearney ,  Brett Eugene Bouma ,  Dvir Yelin

    发明人： Guillermo J. Tearney ,  Brett Eugene Bouma ,  Dvir Yelin

    IPC分类号： A61B1/07 ,  A61B18/22 ,  A61B5/00

    CPC分类号： A61B1/07 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/0086 ,  A61B18/22 ,  A61B2017/00061

    摘要： Exemplary apparatus and process can be provided for imaging information associated with at least one portion of a sample. For example, (i) at least two first different wavelengths of at least one first electro-magnetic radiation can be provided within a first wavelength range provided on the portion of the sample so as to determine at least one first transverse location of the portion, and (ii) at least two second different wavelengths of at least one second electro-magnetic radiation are provided within a second wavelength range provided on the portion so as to determine at least one second transverse location of the portion. The first and second ranges can east partially overlap on the portion. Further, a relative phase between at least one third electro-magnetic radiation electro-magnetic radiation being returned from the sample and at least one fourth electro-magnetic radiation returned from a reference can be obtained to determine a relative depth location of the portion. First information of the portion based on the first transverse location and the relative depth location, and second information of the portion based on the second transverse location and the relative depth location can be obtained. The imaging information may include the first and second information.

    摘要翻译： 可以提供示例性装置和过程用于与样品的至少一部分相关联的成像信息。 例如，（i）至少两个第一不同波长的至少一个第一电磁辐射可以在提供在样品部分上的第一波长范围内提供，以便确定该部分的至少一个第一横向位置， 和（ii）至少两个第二不同波长的至少一个第二电磁辐射被提供在设置在该部分上的第二波长范围内，以便确定该部分的至少一个第二横向位置。 第一和第二范围可以在该部分上部分重叠。 此外，可以获得从样品返回的至少一个第三电磁辐射电磁辐射与从基准返回的至少一个第四电磁辐射之间的相对相位，以确定该部分的相对深度位置。 可以获得基于第一横向位置和相对深度位置的部分的第一信息，以及基于第二横向位置和相对深度位置的部分的第二信息。 成像信息可以包括第一和第二信息。

    Spectrally-encoded endoscopy techniques, apparatus and methods
    128.
    发明授权
    Spectrally-encoded endoscopy techniques, apparatus and methods 有权
    光谱编码的内窥镜检查技术，仪器和方法

    公开(公告)号：US08818149B2

    公开(公告)日：2014-08-26

    申请号：US13427463

    申请日：2012-03-22

    申请人： Milen Shishkov ,  Guillermo J. Tearney ,  Brett Eugene Bouma ,  Dvir Yelin ,  Nicusor Iftimia

    发明人： Milen Shishkov ,  Guillermo J. Tearney ,  Brett Eugene Bouma ,  Dvir Yelin ,  Nicusor Iftimia

    IPC分类号： G02B6/32 ,  G02B6/34 ,  G02B6/06

    CPC分类号： G02B23/2453 ,  A61B1/00167 ,  A61B1/00188 ,  A61B1/002 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0068 ,  A61B5/0084 ,  A61B5/0086 ,  B24B9/14 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/18 ,  G02B5/18 ,  G02B23/2469 ,  G02B23/26

    摘要： Exemplary apparatus for obtaining information for a structure can be provided. For example, the exemplary apparatus can include at least one first optical fiber arrangement which is configured to transceive at least one first electro-magnetic radiation, and can include at least one fiber. The exemplary apparatus can also include at least one second focusing arrangement in optical communication with the optical fiber arrangement. The second arrangement can include a ball lens, and be configured to focus and provide there through the first electro-magnetic radiation to generate the focused electro-magnetic radiation. Further, the exemplary apparatus can include at least at least one dispersive third arrangement which can receive a particular radiation (e.g., the first electro-magnetic radiation(s) and/or the focused electro-magnetic radiation), and forward a dispersed radiation thereof to at least one section of the structure.

    摘要翻译： 可以提供用于获得结构信息的示例性装置。 例如，示例性装置可以包括被配置为收发至少一个第一电磁辐射的至少一个第一光纤布置，并且可以包括至少一个光纤。 示例性装置还可以包括与光纤布置光学通信的至少一个第二聚焦装置。 第二布置可以包括球形透镜，并且被配置成通过第一电磁辐射聚焦并提供在其上，以产生聚焦的电磁辐射。 此外，示例性装置可以包括至少一个能够接收特定辐射（例如，第一电磁辐射和/或聚焦电磁辐射）的分散第三装置，并且将其分散的辐射 到结构的至少一个部分。