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公开(公告)号:US20140142563A1
公开(公告)日:2014-05-22
申请号:US14131518
申请日:2012-07-05
申请人: Bernardus Hendrikus Wilhelmus Hendriks , Nicolaas Jan Noordhoek , Gerhardus Wilhelmus Lucassen , Pieter Maria Mielekamp , Rami Nachabé , Marjolein Van Der Voort , Waltherus Cornelis Jozef Bierhoff
发明人: Bernardus Hendrikus Wilhelmus Hendriks , Nicolaas Jan Noordhoek , Gerhardus Wilhelmus Lucassen , Pieter Maria Mielekamp , Rami Nachabé , Marjolein Van Der Voort , Waltherus Cornelis Jozef Bierhoff
CPC分类号: A61B34/10 , A61B18/14 , A61B2018/00577 , A61B2034/101
摘要: The invention relates to an energy application planning apparatus for planning an application of energy to an object (3) like a tumor. An energy application element representation represents an energy application element (5) like an ablation needle including an energy application part for applying energy and a sensing part (7). An arrangement of the energy application element (5) with respect to the object (3) is determined depending on the positions of the energy application part and the sensing part (7) with respect to the energy application element (5) as defined by the energy application element representation and depending on the object representation. The application of energy can therefore not only be planned such that the application of energy is performed as desired, but also such that the object and/or a surrounding of the object are sensible as desired. In this way, the planning procedure can be improved.
摘要翻译: 本发明涉及一种能量应用计划装置,用于规划能量到诸如肿瘤的物体(3)的应用。 能量应用元件表示代表诸如包括用于施加能量的能量施加部分和感测部分(7)的消融针的能量施加元件(5)。 能量施加元件(5)相对于物体(3)的布置根据能量施加部分和感测部分(7)相对于能量施加元件(5)的位置来确定,如由 能量应用元素表示,并取决于对象表示。 因此,能量的施加不仅可以被规划,使得能量的应用按照需要执行,而且还使得物体和/或物体的周围是期望的。 这样可以提高规划程序。
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公开(公告)号:US20140121538A1
公开(公告)日:2014-05-01
申请号:US14127692
申请日:2012-06-13
申请人: Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Gerhardus Wilhelmus Lucassen , Jeroen Jan Lambertus Horiks , Susanne Dorien Van Den Bergdams , Christian Reich , Stephan Voss , Axel Winkel , Rami Nachabe , Manfred Muller , Marjolein Van Der Voort
发明人: Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Gerhardus Wilhelmus Lucassen , Jeroen Jan Lambertus Horiks , Susanne Dorien Van Den Bergdams , Christian Reich , Stephan Voss , Axel Winkel , Rami Nachabe , Manfred Muller , Marjolein Van Der Voort
CPC分类号: A61B1/00009 , A61B1/0646 , A61B1/0684 , A61B1/07 , A61B5/0071 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/6848 , A61B10/0233 , F04C2270/0421 , Y10T29/49826
摘要: A needle is proposed including a cannula or hollow shaft with a multilumen insert inside. The insert comprises at least two lumen. Both the insert as well as the cannula have bevelled ends. In the insert substantially straight cleaved fibers are present that may be connected at the proximal end to a console. At least one of the distal fiber ends in the insert may protrude more than half the fiber diameter out of the insert. Furthermore, the bevel angle of the insert is different from the bevel angle of the cannula such that combination cannula and insert is such that the fiber ends do not protrude the bevel surface of the cannula.
摘要翻译: 提出了一种针头,其中包括插入件或空心轴,其中具有多孔插入件。 插入件包括至少两个内腔。 插入件以及套管均具有倾斜端部。 在插入件中,存在基本上直的切割的纤维,其可以在近端连接到控制台。 插入件中的远端纤维端部中的至少一个可以突出超过插入件的纤维直径的一半以上。 此外,插入件的斜角与插管的斜角不同,使得组合插管和插入件使得纤维端部不突出套管的斜面。
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公开(公告)号:US09468379B2
公开(公告)日:2016-10-18
申请号:US13641229
申请日:2011-04-18
申请人: Bernardus Hendrikus Wilhelmus Hendriks , Jeroen Jan Lambertus Horikx , Gerhardus Wilhelmus Lucassen , Rami Nachabe , Marjolein Van Der Voort
发明人: Bernardus Hendrikus Wilhelmus Hendriks , Jeroen Jan Lambertus Horikx , Gerhardus Wilhelmus Lucassen , Rami Nachabe , Marjolein Van Der Voort
IPC分类号: G01N21/359 , A61B5/00
CPC分类号: A61B5/0059 , A61B5/4869 , G01N21/359
摘要: The present invention relates to an apparatus, a method and a computer program for determining a lipid-water ratio and a scattering parameter of a sample. In particular, the invention relates to an apparatus comprising a light source and a detector arranged to measure an optical parameter at various wavelengths, where the wavelengths are selected so that at two of the wavelengths the absorption coefficients for both water and lipids are substantially identical. This enables determination of a scattering parameter. A further measurement at a third wavelength enables determination of a water-lipid ratio. According to a specific embodiment, the light source and the detector are arranged in relation to an interventional device, so as to be able to examine a tissue in terms of lipid-water ratio and scattering during an intervention.
摘要翻译: 本发明涉及一种用于确定样品的脂质 - 水比和散射参数的装置,方法和计算机程序。 具体地,本发明涉及一种包括光源和检测器的设备,其被布置成测量各种波长的光学参数,其中选择波长使得在两个波长处,水和脂质的吸收系数基本相同。 这使得能够确定散射参数。 在第三波长处的进一步测量使得能够测定水 - 油比。 根据具体实施例,光源和检测器相对于介入装置布置,以便能够在干预期间根据脂质 - 水比和散射来检查组织。
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公开(公告)号:US09757201B2
公开(公告)日:2017-09-12
申请号:US14131518
申请日:2012-07-05
申请人: Bernardus Hendrikus Wilhelmus Hendriks , Nicolaas Jan Noordhoek , Gerhardus Wilhelmus Lucassen , Pieter Maria Mielekamp , Rami Nachabė , Marjolein Van Der Voort , Waltherus Cornelis Jozef Bierhoff
发明人: Bernardus Hendrikus Wilhelmus Hendriks , Nicolaas Jan Noordhoek , Gerhardus Wilhelmus Lucassen , Pieter Maria Mielekamp , Rami Nachabė , Marjolein Van Der Voort , Waltherus Cornelis Jozef Bierhoff
CPC分类号: A61B34/10 , A61B18/14 , A61B2018/00577 , A61B2034/101
摘要: The invention relates to an energy application planning apparatus for planning an application of energy to an object (3) like a tumor. An energy application element representation represents an energy application element (5) like an ablation needle including an energy application part for applying energy and a sensing part (7). An arrangement of the energy application element (5) with respect to the object (3) is determined depending on the positions of the energy application part and the sensing part (7) with respect to the energy application element (5) as defined by the energy application element representation and depending on the object representation. The application of energy can therefore not only be planned such that the application of energy is performed as desired, but also such that the object and/or a surrounding of the object are sensible as desired. In this way, the planning procedure can be improved.
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公开(公告)号:US20140117256A1
公开(公告)日:2014-05-01
申请号:US14127719
申请日:2012-06-21
申请人: Manfred Mueller , Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Gerhardus Wilhelmus Lucassen , Jeroen Jan Lambertus Horikx , Rami Nachabe , Marjolein Van Der Voort
发明人: Manfred Mueller , Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Gerhardus Wilhelmus Lucassen , Jeroen Jan Lambertus Horikx , Rami Nachabe , Marjolein Van Der Voort
IPC分类号: A61B5/00
CPC分类号: A61B5/0071 , A61B5/0075 , A61B5/0084
摘要: In order to improve fluorescence measurements, there is provided an apparatus and, a method and a computer program for optical analysis of an associated tissue sample, the apparatus comprising a spectrometer comprising an optical detector, a light source, a first light emitter 219 arranged for emitting photons into the associated tissue sample, a first light collector 221 arranged for receiving photons from the associated tissue sample, a second light emitter 223, a second light collector 225, wherein a reflectance spectrum is obtained via the first light emitter 219 and collector 221 and a fluorescence spectrum is obtained via the second light emitter 223 and collector 225, and where a first distance d1 between the first light emitter and collector is larger than a second distance d2 between the second light emitter and collector. By combining the data thus obtained, an intrinsic fluorescence spectrum may be obtained.
摘要翻译: 为了改进荧光测量,提供了一种用于相关组织样本的光学分析的装置和方法以及计算机程序,该装置包括光谱仪,该光谱仪包括光学检测器,光源,第一光发射器219, 将光子发射到相关联的组织样本中,布置成从相关联的组织样本接收光子的第一光收集器221,第二光发射器223,第二光收集器225,其中通过第一光发射器219和集电极221获得反射光谱 并且通过第二光发射器223和集电极225获得荧光光谱,并且其中第一光发射器和集电极之间的第一距离d1大于第二发光体和集电极之间的第二距离d2。 通过组合由此获得的数据,可以获得固有的荧光光谱。
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公开(公告)号:US20140046197A1
公开(公告)日:2014-02-13
申请号:US14112555
申请日:2012-04-10
CPC分类号: A61B5/0075 , A61B1/00 , A61B5/0071 , A61B5/0084 , A61B5/0091 , A61B5/4887 , A61B5/6848 , A61B5/6852 , G01N21/64 , G01N2021/6421
摘要: The present invention deals with discrimination of malignant tissue from normal and benign tissue in a single patient on the basis of optical spectroscopic measurements. Starting from spectroscopic measurements in normal tissue, reference values are obtained for the normal class. With spectroscopic measurements in other tissues data points can be assigned to new class(es) when the spectral characteristics fall outside a threshold defining the reference class. Thresholds between different classes can also be defined. Finding (the transition to) malignant tissue is based on comparing the spectroscopic values to the classification threshold discriminating normal and benign versus malignant tissue. Thus, the basis of normal spectroscopic measurements is tuned to the individual patient characteristic. Discriminating the normal plus benign and malignant from that reference is more efficient compared to the reference of the all patient database.
摘要翻译: 本发明基于光学光谱测量法处理单个患者中恶性组织与正常和良性组织的鉴别。 从正常组织中的光谱测量开始,获得正常类的参考值。 通过在其他组织中的光谱测量,当光谱特性落在定义参考类的阈值之外时,可以将数据点分配给新类。 也可以定义不同类之间的阈值。 寻找(过渡到)恶性组织是基于将光谱值与鉴别正常和良性与恶性组织的分类阈值进行比较。 因此,正常光谱测量的基础被调整到个体患者的特征。 与所有患者数据库的参考相比,从该参考文献中区分正常和良性和恶性的效果更高。
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公开(公告)号:US20130217989A1
公开(公告)日:2013-08-22
申请号:US13881379
申请日:2011-10-17
申请人: Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Gerhardus Wilhelmus Lucassen , Rami Nachabe , Theodoor Jacques Marie Ruers
发明人: Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Gerhardus Wilhelmus Lucassen , Rami Nachabe , Theodoor Jacques Marie Ruers
IPC分类号: A61B5/1459
CPC分类号: A61B5/1459 , A61B5/0075 , A61B5/0084 , A61B5/6848 , A61B5/6882 , A61M25/065
摘要: A needle comprises an elongated first shaft element with a C-shaped cross section and an elongated second shaft element with a C-shaped cross section. The first shaft element and the second shaft element are adapted to be detachably connected to each other. This is achieved by an overlap of respective end sections of the first and second shaft elements. Within the channel formed by the shaft elements, an optical probe may be accommodated from which the shaft elements may be removed by separating the two shaft elements from each other.
摘要翻译: 针包括具有C形横截面的细长的第一轴元件和具有C形横截面的细长的第二轴元件。 第一轴元件和第二轴元件适于彼此可拆卸地连接。 这通过第一和第二轴元件的相应端部部分的重叠来实现。 在由轴元件形成的通道内,可以容纳光学探针,通过将两个轴元件彼此分离,可以从中移除轴元件。
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公开(公告)号:US09980698B2
公开(公告)日:2018-05-29
申请号:US13321189
申请日:2010-05-07
IPC分类号: A61B19/00 , G06T7/00 , A61B5/00 , A61B6/12 , A61B8/08 , A61B6/00 , A61B17/34 , A61B8/00 , A61B90/00
CPC分类号: A61B8/0841 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0071 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/6848 , A61B6/12 , A61B6/5247 , A61B8/00 , A61B8/5238 , A61B17/34 , A61B17/3403 , A61B17/3417 , A61B2090/3614 , A61B2090/374 , A61B2090/376 , A61B2090/378 , A61B2090/3784
摘要: Re-calibration of pre-recorded images during interventions uses an interventional system including an imaging device providing images of an object, a needle device, and a processing device. The needle device includes a sensor for providing data corresponding to tissue properties. The processing device is configured to perform an overlay registration of pre-recorded images and live images provided by the imaging device, utilizing the data from the sensor. Thus, the accuracy of an overlay of images is increased.
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公开(公告)号:US09131846B2
公开(公告)日:2015-09-15
申请号:US13125392
申请日:2009-10-19
申请人: Franciscus Martinus Antonius Maria Van Gaal , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Cornelius Antonius Hezemans , Waltherus Cornelis Jozef Bierhoff
发明人: Franciscus Martinus Antonius Maria Van Gaal , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Cornelius Antonius Hezemans , Waltherus Cornelis Jozef Bierhoff
CPC分类号: A61B5/0062 , A61B5/0084 , G02B23/2461 , G02B26/103
摘要: An optical scanning probe assembly for microscopic guide optic scanning and inspection of tissues includes an outer housing having a spring element for a scanning motor. The spring element is formed as a hollow tube configured to receive an optical guide, where the hollow tube has a mechanical stiffness larger than the optical guide to be received. The assembly further includes a lens system and a deflector configured to deflect the distal end of the hollow tube in directions transverse to the longitudinal extension of the hollow tube, so as to form an optical scan pattern.
摘要翻译: 用于微小导向光学扫描和组织检查的光学扫描探针组件包括具有用于扫描电机的弹簧元件的外壳。 弹簧元件形成为构造成接收光导的中空管,其中中空管具有比要接收的光导更大的机械刚度。 组件还包括透镜系统和偏转器,其被配置为使中空管的远端沿垂直于中空管的纵向延伸的方向偏转,以形成光学扫描图案。
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公开(公告)号:US09107694B2
公开(公告)日:2015-08-18
申请号:US13146223
申请日:2010-01-25
申请人: Bernardus Hendrikus Wilhelmus Hendriks , Adrien Emmanuel Desjardins , Martin Franciscus McKinney
发明人: Bernardus Hendrikus Wilhelmus Hendriks , Adrien Emmanuel Desjardins , Martin Franciscus McKinney
IPC分类号: G01N23/04 , H05G1/08 , A61B17/34 , A61B6/12 , A61B6/00 , G06F19/00 , H05B33/08 , A61B19/00 , A61B17/00
CPC分类号: A61B17/3403 , A61B6/12 , A61B6/463 , A61B6/464 , A61B6/467 , A61B34/25 , A61B90/30 , A61B2017/00035 , A61B2017/00061 , A61B2017/00084 , A61B2017/00128 , A61B2034/107 , A61B2034/254 , A61B2090/372 , A61B2090/376 , G06F19/00 , G06F19/321 , H05B33/0803
摘要: The present invention relates to an examination apparatus for providing information about an object and a method for providing information about an object of interest. In order to improve the visual reception of information relating to the object, an examination apparatus is provided that comprises an examination arrangement and a control unit with at least a first interface and a second interface. The examination arrangement is adapted to detect object data from at least one region of interest of an object and to provide the object data to the control unit. Further, the control unit is adapted to compute object data into object information and to transform at least a part of the object information into image data (32, 36). Further, the control unit is arranged to extract pre-determined indicative data from the object information and to transform the indicative data into graphical advisory data (40). The first interface is configured such to provide the image data to a display unit (20) in order to display the image data (32, 36) to the user. The second interface is configured such to provide a signal for an ambient advice display arrangement in order to provide the graphical advisory data (40) to the user.
摘要翻译: 本发明涉及一种用于提供关于对象的信息的检查装置和用于提供关于感兴趣对象的信息的方法。 为了改善与对象有关的信息的视觉接收,提供一种检查装置,其包括检查装置和具有至少第一接口和第二接口的控制单元。 检查装置适于从对象的至少一个感兴趣区域检测对象数据,并将对象数据提供给控制单元。 此外,控制单元适于将对象数据计算为对象信息并将对象信息的至少一部分转换为图像数据(32,36)。 此外,控制单元被布置成从对象信息提取预定指示数据,并将指示性数据变换成图形咨询数据(40)。 第一接口被配置为将图像数据提供给显示单元(20),以便向用户显示图像数据(32,36)。 第二接口被配置为提供用于环境咨询显示装置的信号,以向用户提供图形咨询数据(40)。
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