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公开(公告)号:US11124829B2
公开(公告)日:2021-09-21
申请号:US16626452
申请日:2019-06-07
Applicant: ILLUMINA, INC. , ILLUMINA CAMBRIDGE LIMITED
Inventor: Jeffrey S. Fisher , Brian D. Mather , Maria Candelaria Rogert Bacigalupo , Justin Fullerton , Ludovic Vincent , Lewis J. Kraft , Sahngki Hong , Boyan Boyanov , M. Shane Bowen , Sang Park , Wayne N. George , Andrew A. Brown , Dajun Yuan
IPC: C12Q1/68 , G03F7/16 , C12Q1/6869 , C08F220/56 , C08G77/04 , G03F7/075 , G03F7/00 , G03F7/004
Abstract: An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.
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公开(公告)号:US20210139975A1
公开(公告)日:2021-05-13
申请号:US17139834
申请日:2020-12-31
Applicant: ILLUMINA, INC. , ILLUMINA CAMBRIDGE LIMITED
Inventor: Jeffrey S. Fisher , Brian D. Mather , Maria Candelaria Rogert Bacigalupo , Justin Fullerton , Ludovic Vincent , Lewis J. Kraft , Sahngki Hong , Boyan Boyanov , M. Shane Bowen , Sang Park , Wayne N. George , Andrew A. Brown , Dajun Yuan
IPC: C12Q1/6869 , C08F220/56 , C08G77/04 , G03F7/075 , G03F7/16
Abstract: An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.
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公开(公告)号:US20210130885A1
公开(公告)日:2021-05-06
申请号:US17145846
申请日:2021-01-11
Applicant: ILLUMINA, INC.
Inventor: Alex So , Li Liu , Min-Jui Richard Shen , Neeraj Salathia , Kathryn M. Stephens , Anne Jager , Timothy Wilson , Justin Fullerton , Sean M. Ramirez , Shannon Kaplan , Rigo Pantoja , Bala Murali Venkatesan , Steven Modiano
IPC: C12Q1/6837 , C12Q1/6874 , C12Q1/6816 , C12Q1/6855
Abstract: Presented are methods and compositions for spatial detection and analysis of nucleic acids in a tissue sample. The methods can enable the characterization of transcriptomes and/or genomic variations in tissues while preserving spatial information about the tissue.
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公开(公告)号:US12172156B2
公开(公告)日:2024-12-24
申请号:US18233289
申请日:2023-08-11
Applicant: ILLUMINA, INC.
Inventor: Lewis J. Kraft , Tarun Kumar Khurana , Yir-Shyuan Wu , Xi-Jun Chen , Arnaud Rival , Justin Fullerton , M. Shane Bowen , Hui Han , Jeffrey S. Fisher , Yasaman Farshchi , Mathieu Lessard-Viger
Abstract: An example of a flow cell includes a substrate, a plurality of chambers defined on or in the substrate, and a plurality of depressions defined in the substrate and within a perimeter of each of the plurality of chambers. The depressions are separated by interstitial regions. Primers are attached within each of the plurality of depressions, and a capture site is located within each of the plurality of chambers.
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公开(公告)号:US20240302738A1
公开(公告)日:2024-09-12
申请号:US18667993
申请日:2024-05-17
Applicant: ILLUMINA, INC.
Inventor: Jeffrey S. Fisher , Brian D. Mather , Maria Candelaria Rogert Bacigalupo , Justin Fullerton , Ludovic Vincent , Lewis J. Kraft , Sahngki Hong , Boyan Boyanov , M. Shane Bowen , Sang Park , Wayne N. George , Andrew A. Brown , Dajun Yuan
IPC: G03F7/00 , C08F220/56 , C08G77/04 , C12Q1/6869 , G03F7/004 , G03F7/075 , G03F7/16
CPC classification number: G03F7/0002 , C08F220/56 , C08G77/04 , C12Q1/6869 , G03F7/0757 , G03F7/165 , G03F7/0046
Abstract: An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.
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公开(公告)号:US11988957B2
公开(公告)日:2024-05-21
申请号:US18317865
申请日:2023-05-15
Applicant: ILLUMINA, INC. , ILLUMINA CAMBRIDGE LIMITED
Inventor: Jeffrey S. Fisher , Brian D. Mather , Maria Candelaria Rogert Bacigalupo , Justin Fullerton , Ludovic Vincent , Lewis J. Kraft , Sahngki Hong , Boyan Boyanov , M. Shane Bowen , Sang Park , Wayne N. George , Andrew A. Brown
IPC: G03F7/00 , C08F220/56 , C08G77/04 , C12Q1/6869 , G03F7/075 , G03F7/16 , G03F7/004
CPC classification number: G03F7/0002 , C08F220/56 , C08G77/04 , C12Q1/6869 , G03F7/0757 , G03F7/165 , G03F7/0046
Abstract: An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.
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公开(公告)号:US20230381733A1
公开(公告)日:2023-11-30
申请号:US18233289
申请日:2023-08-11
Applicant: ILLUMINA, INC.
Inventor: Lewis J. Kraft , Tarun Kumar Khurana , Yir-Shyuan Wu , Xi-Jun Chen , Arnaud Rival , Justin Fullerton , M. Shane Bowen , Hui Han , Jeffrey S. Fisher , Yasaman Farshchi , Mathieu Lessard-Viger
CPC classification number: B01J19/0046 , C12N15/1065 , C40B40/08 , C08L37/00 , C40B50/18 , B01L3/502707 , B01L3/5027
Abstract: An example of a flow cell includes a substrate, a plurality of chambers defined on or in the substrate, and a plurality of depressions defined in the substrate and within a perimeter of each of the plurality of chambers. The depressions are separated by interstitial regions. Primers are attached within each of the plurality of depressions, and a capture site is located within each of the plurality of chambers.
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公开(公告)号:US11779897B2
公开(公告)日:2023-10-10
申请号:US17515511
申请日:2021-10-31
Applicant: ILLUMINA, INC.
Inventor: Lewis J. Kraft , Tarun Kumar Khurana , Yir-Shyuan Wu , Xi-Jun Chen , Arnaud Rival , Justin Fullerton , M. Shane Bowen , Hui Han , Jeffrey S. Fisher , Yasaman Farshchi , Mathieu Lessard-Viger
CPC classification number: B01J19/0046 , B01L3/5027 , B01L3/502707 , C12N15/1065 , C40B40/08 , C40B50/18 , B01J2219/00286 , B01J2219/00608 , B01L2300/0819 , B01L2300/0877 , C08L37/00 , G01N2021/058
Abstract: An example of a flow cell includes a substrate, a plurality of chambers defined on or in the substrate, and a plurality of depressions defined in the substrate and within a perimeter of each of the plurality of chambers. The depressions are separated by interstitial regions. Primers are attached within each of the plurality of depressions, and a capture site is located within each of the plurality of chambers.
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公开(公告)号:US11192083B2
公开(公告)日:2021-12-07
申请号:US16750831
申请日:2020-01-23
Applicant: ILLUMINA, INC.
Inventor: Lewis J. Kraft , Tarun Kumar Khurana , Yir-Shyuan Wu , Xi-Jun Chen , Arnaud Rival , Justin Fullerton , M. Shane Bowen , Hui Han , Jeffrey S. Fisher , Yasaman Farshchi , Mathieu Lessard-Viger
Abstract: An example of a flow cell includes a substrate, a plurality of chambers defined on or in the substrate, and a plurality of depressions defined in the substrate and within a perimeter of each of the plurality of chambers. The depressions are separated by interstitial regions. Primers are attached within each of the plurality of depressions, and a capture site is located within each of the plurality of chambers.
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公开(公告)号:US20200238247A1
公开(公告)日:2020-07-30
申请号:US16750831
申请日:2020-01-23
Applicant: ILLUMINA, INC.
Inventor: Lewis J. Kraft , Tarun Kumar Khurana , Yir-Shyuan Wu , Xi-Jun Chen , Arnaud Rival , Justin Fullerton , M. Shane Bowen , Hui Han , Jeffrey S. Fisher , Yasaman Farshchi , Mathieu Lessard-Viger
Abstract: An example of a flow cell includes a substrate, a plurality of chambers defined on or in the substrate, and a plurality of depressions defined in the substrate and within a perimeter of each of the plurality of chambers. The depressions are separated by interstitial regions. Primers are attached within each of the plurality of depressions, and a capture site is located within each of the plurality of chambers.
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