公开(公告)号：US20180125401A1

公开(公告)日：2018-05-10

申请号：US15863287

申请日：2018-01-05

Applicant: DexCom, Inc.

Inventor： Paul V. Goode, JR. ,  James H. Brauker ,  Apurv Ullas Kamath ,  James Patrick Thrower

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/1486

CPC classification number: A61B5/14532 ,  A61B5/0015 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/7275 ,  A61B5/742 ,  G16H40/40 ,  Y02A90/26

Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

公开(公告)号：US09937293B2

公开(公告)日：2018-04-10

申请号：US14830568

申请日：2015-08-19

Applicant: DexCom, Inc.

Inventor： James H. Brauker ,  Mark A. Tapsak ,  Sean T. Saint ,  Apurv Ullas Kamath ,  Paul V. Neale ,  Peter C. Simpson ,  Michael Robert Mensinger ,  Dubravka Markovic

IPC: A61M31/00 ,  A61M1/00 ,  A61M5/315 ,  A61B5/1486 ,  A61M15/00 ,  A61M11/00 ,  A61B5/00 ,  A61B5/145 ,  G06F19/00 ,  A61M5/172

CPC classification number: A61M5/31525 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/4839 ,  A61B2560/0443 ,  A61M5/1723 ,  A61M11/00 ,  A61M15/0001 ,  A61M2005/1726 ,  A61M2205/18 ,  A61M2205/3303 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468 ,  G16H20/17 ,  G16H40/63

Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

公开(公告)号：US09918668B2

公开(公告)日：2018-03-20

申请号：US15065623

申请日：2016-03-09

Applicant: DexCom, Inc.

Inventor： Jack Pryor ,  Apurv Ullas Kamath ,  Paul V. Goode, Jr. ,  James H. Brauker

IPC: A61B5/1495 ,  A61B5/1473 ,  A61B5/1468 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/145

CPC classification number: A61B5/1495 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/14735 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2560/0223

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US09895089B2

公开(公告)日：2018-02-20

申请号：US14283123

申请日：2014-05-20

Applicant: DexCom, Inc.

Inventor： Paul V. Goode, Jr. ,  James H. Brauker ,  Apurv Ullas Kamath ,  James Patrick Thrower

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495 ,  G06F19/00

CPC classification number: A61B5/14532 ,  A61B5/0015 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/7275 ,  A61B5/742 ,  G16H40/40 ,  Y02A90/26

Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

公开(公告)号：US20180014762A1

公开(公告)日：2018-01-18

申请号：US15719298

申请日：2017-09-28

Applicant: DexCom, Inc.

Inventor： Mark C. Brister ,  Paul V. Neale ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/1473 ,  A61B17/34 ,  A61B5/15 ,  A61B5/1495 ,  A61B5/1486 ,  A61B5/05 ,  A61B5/00 ,  A61M5/14 ,  A61M5/172 ,  A61M5/142 ,  A61M5/158

CPC classification number: A61B5/14532 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/05 ,  A61B5/14 ,  A61B5/1411 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14507 ,  A61B5/14514 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/14735 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/150022 ,  A61B5/6801 ,  A61B5/6833 ,  A61B5/68335 ,  A61B5/6848 ,  A61B5/6849 ,  A61B5/72 ,  A61B17/3468 ,  A61B2017/3492 ,  A61B2560/0223 ,  A61B2560/045 ,  A61B2562/18 ,  A61M5/14244 ,  A61M5/1723 ,  A61M2005/1585 ,  Y02A90/26

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US09833143B2

公开(公告)日：2017-12-05

申请号：US14296735

申请日：2014-06-05

Applicant: DexCom, Inc.

Inventor： Mark Brister ,  Paul V. Neale ,  Peter C. Simpson ,  James H. Brauker ,  James Patrick Thrower ,  Mark Shults ,  Rathbun K. Rhodes ,  Paul V. Goode, Jr. ,  Arnold L. Holmquist

IPC: A61B5/1473 ,  H04B1/03 ,  A61B5/00 ,  A61B5/07 ,  A61B5/145

CPC classification number: A61B5/0015 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B2560/04 ,  A61B2560/0462 ,  A61B2562/247 ,  H04B1/03

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US09827372B2

公开(公告)日：2017-11-28

申请号：US15362571

申请日：2016-11-28

Applicant: DexCom, Inc.

Inventor： John Michael Dobbles ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  James H. Brauker

IPC: A61M5/172 ,  A61B5/145 ,  A61M5/142 ,  A61M11/00 ,  G06F19/00 ,  A61M5/20 ,  A61M35/00 ,  A61B5/00 ,  A61M5/00 ,  A61M5/178 ,  A61M5/30 ,  A61M15/00

CPC classification number: A61M5/1723 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14546 ,  A61M5/003 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/178 ,  A61M5/20 ,  A61M5/30 ,  A61M11/00 ,  A61M15/00 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/008 ,  A61M15/0083 ,  A61M35/00 ,  A61M2005/14296 ,  A61M2205/3569 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/587 ,  A61M2205/8206 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468 ,  G16H40/63

Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.

公开(公告)号：US09788766B2

公开(公告)日：2017-10-17

申请号：US14281697

申请日：2014-05-19

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker

IPC: A61B5/05 ,  A61B5/145 ,  A61B5/1486 ,  C12Q1/00 ,  B33Y80/00 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/0031 ,  A61B5/1486 ,  A61B5/14865 ,  B33Y80/00 ,  C12Q1/001 ,  C12Q1/006

Abstract: Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.

公开(公告)号：US09724045B1

公开(公告)日：2017-08-08

申请号：US15481347

申请日：2017-04-06

Applicant: DexCom, Inc.

Inventor： Paul V. Goode, Jr. ,  James H. Brauker ,  Apurv U. Kamath ,  James Patrick Thrower ,  Victoria Carr-Brendel

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495

CPC classification number: A61B5/7203 ,  A61B5/0004 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/7225 ,  A61B5/7257 ,  A61B5/726 ,  A61B5/7278 ,  A61B5/742 ,  A61B5/7475 ,  A61B2560/0223 ,  A61B2562/0247 ,  A61B2562/0271 ,  A61B2562/08

Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.

公开(公告)号：US09724028B2

公开(公告)日：2017-08-08

申请号：US14552398

申请日：2014-11-24

Applicant: DexCom, Inc.

Inventor： James H. Brauker ,  Apurv Ullas Kamath

IPC: A61B5/1473 ,  A61B5/1495 ,  A61B5/15 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/151 ,  A61B5/00

CPC classification number: A61B5/1473 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/1411 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/15142 ,  A61B5/72 ,  A61B5/742 ,  A61B5/746

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.