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93 条记录 (耗时 0.04 秒)

    Optical detector for a particle sorting system
    26.
    发明申请
    Optical detector for a particle sorting system 有权
    用于粒子分选系统的光学检测器

    公开(公告)号：US20050128479A1

    公开(公告)日：2005-06-16

    申请号：US10915016

    申请日：2004-08-09

    申请人： John Gilbert ,  Edward Sinofsky ,  Manish Deshpande

    发明人： John Gilbert ,  Edward Sinofsky ,  Manish Deshpande

    IPC分类号： G01N15/14 ,  G01N21/00 ,  G01N21/64 ,  G01N21/88 ,  H01L20060101

    CPC分类号： G01N15/1434 ,  G01N15/1459 ,  G01N15/1484 ,  G01N21/6452 ,  G01N2015/1081

    摘要： An optical system for acquiring fast spectra from spatially channel arrays includes a light source for producing a light beam that passes through the microfluidic chip or the channel to be monitored, one or more lenses or optical fibers for capturing the light from the light source after interaction with the particles or chemicals in the microfluidic channels, and one or more detectors. The detectors, which may include light amplifying elements, detect each light signal and transducer the light signal into an electronic signal. The electronic signals, each representing the intensity of an optical signal, pass from each detector to an electronic data acquisition system for analysis. The light amplifying element or elements may comprise an array of phototubes, a multianode phototube, or a multichannel plate based image intensifier coupled to an array of photodiode detectors.

    摘要翻译： 用于从空间通道阵列获取快速光谱的光学系统包括用于产生穿过微流体芯片或待监测通道的光束的光源，用于在相互作用之后捕获来自光源的光的一个或多个透镜或光纤 微流体通道中的颗粒或化学物质，以及一个或多个检测器。 可以包括光放大元件的检测器检测每个光信号并将光信号转换成电子信号。 每个表示光信号强度的电子信号从每个检测器传递到电子数据采集系统进行分析。 光放大元件可以包括耦合到光电二极管检测器阵列的光管阵列，多子光电管或基于多通道板的图像增强器。

    Automated quoting of molds and molded parts
    27.
    发明申请
    Automated quoting of molds and molded parts 有权
    自动报价模具和模压件

    公开(公告)号：US20050096780A1

    公开(公告)日：2005-05-05

    申请号：US10970130

    申请日：2004-10-21

    申请人： Lawrence Lukis ,  Yuri Dreizin ,  John Gilbert

    发明人： Lawrence Lukis ,  Yuri Dreizin ,  John Gilbert

    IPC分类号： B22C19/04 ,  B29C33/38 ,  G06Q30/00 ,  B29C39/00

    CPC分类号： B22C19/04 ,  B29C33/3835 ,  G06Q30/06

    摘要： Automated, custom mold manufacture for a part begins by creating and storing a collection of information of standard tool geometries and surface profiles machinable by each of the standard tool geometries. A customer sends a CAD file for the part to be molded to the system. The system assesses the CAD file to determine various pieces of mold manufacturing information. One or more acceptability criteria are applied to the part, such as whether the part can be manufactured in a two-piece, straight-pull mold, and whether the mold can by CNC machined out of aluminum. If not, the system sends a file to the customer graphically indicating which portions of the part need modification to be manufacturable. The system provides the customer with a quotation form, that allows the customer to select several parameters, such as number of cavities, surface finish and material, which an independent of the shape of the part. The quotation module then provides the customer with the cost to manufacture the mold or a number of parts. The quotation is based in part upon mold manufacturing time as automatically assessed from the part drawings and based in part on the independent parameters selected by the customer. The customer's part is geometrically assessed so the system automatically selects appropriate tools and computes tool paths for mold manufacture. In addition to the part cavity, the system preferably assesses the parting line, the shutoff surfaces, the ejection pins and the runners and gates for the mold. The preferred system then generates CNC machining instructions to manufacture the mold, and the mold is manufactured in accordance with these instructions.

    摘要翻译： 零件的自动定制模具制造开始于创建和存储标准工具几何和表面轮廓信息的集合，这些信息可通过每种标准工具几何形状加工。 一个客户发送一个CAD文件，用于要模制到该系统的零件。 该系统评估CAD文件以确定各种模具制造信息。 一个或多个可接受性标准被应用于零件，例如该零件是否可以以两件式的直拉模具制造，以及模具是否可以通过铝加工而成。 如果没有，则系统以图形方式向客户发送文件，指示部件的哪些部分需要修改才能制造。 该系统为客户提供了一种报价单，允许客户选择几个参数，如空腔数量，表面光洁度和材料，独立于零件的形状。 报价模块然后为客户提供制造模具或多个零件的成本。 报价部分基于模具制造时间，部分由零件图纸自动评估，部分依据客户选择的独立参数。 客户的部件进行几何评估，以便系统自动选择合适的工具并计算出模具制造的刀具路径。 除了部分空腔之外，系统还优选地评估分模线，关闭表面，弹出销和用于模具的流道和浇口。 优选的系统然后产生CNC加工说明以制造模具，并且模具根据这些说明书制造。

    Magnetic resonance imaging assisted cryosurgery
    29.
    发明授权
    Magnetic resonance imaging assisted cryosurgery 失效
    磁共振成像辅助冷冻手术

    公开(公告)号：US5706810A

    公开(公告)日：1998-01-13

    申请号：US461253

    申请日：1995-06-02

    申请人： Boris Rubinsky ,  John Gilbert ,  San Wong ,  Mark Roos ,  Grant Pease

    发明人： Boris Rubinsky ,  John Gilbert ,  San Wong ,  Mark Roos ,  Grant Pease

    IPC分类号： A61B18/02 ,  A61B19/00 ,  G01R33/28 ,  G01R33/561 ,  A61B5/055

    CPC分类号： A61B18/02 ,  G01R33/28 ,  A61B2018/0262 ,  A61B2090/374 ,  A61B90/10 ,  G01R33/56308

    摘要： Methods and apparatus for magnetic resonance imaging (MRI) assisted cryosurgery. Optimal probe placements and cooling parameters are calculated prior to cryosurgery using MRI data. A MRI compatible cryoprobe and a stereotactic probe positioning device are provided. The resolution of MR images is enhanced by mounting a radio frequency MR coil on the intracorporeal end of a cryoprobe. During cryosurgery the temperature distribution in the frozen region is solved by determining the boundary of the frozen region and solving the heat equation for the known boundary conditions. During cryosurgery the temperature distribution in the unfrozen region is determined by T1 measurements. The process of freezing is controlled using information from the solution of the energy equation in the frozen region and temperature measurements in the unfrozen region. After cryosurgery the extent of the tissue damage may be ascertained using phosphorus-31 and/or sodium-23 spectroscopy with a special coil set on the cryosurgical probe.

    摘要翻译： 磁共振成像（MRI）辅助冷冻手术的方法和装置。 在使用MRI数据进行冷冻手术之前计算最佳探针放置和冷却参数。 提供MRI兼容的冷冻探针和立体定向探针定位装置。 通过将射频MR线圈安装在冷冻探针的体内末端来增强MR图像的分辨率。 在冷冻手术中，通过确定冻结区域的边界并求解已知边界条件的热方程来解决冻结区域的温度分布。 在冷冻手术中，未冻结区域的温度分布由T1测量确定。 使用来自冻结区域的能量方程的解和来自未冻结区域的温度测量的信息来控制冷冻过程。 在冷冻手术之后，可以使用在冷冻手术探针上设置的特殊线圈的磷-31和/或钠-23光谱来确定组织损伤的程度。

    Method and apparatus for waking-up violin and other string instruments
    30.
    发明授权
    Method and apparatus for waking-up violin and other string instruments 有权

    公开(公告)号：US10121457B2

    公开(公告)日：2018-11-06

    申请号：US15423313

    申请日：2017-02-02

    申请人： John Gilbert

    发明人： John Gilbert

    IPC分类号： G10H3/00 ,  G10D1/00

    摘要： Waking-up a violin or other instrument by determining naturally resonating features of a particular instrument by applying tones and analyzing the instrument's responses, and then applying vibrations (e.g., continuously and/or in patterns, such as alternating on/off, staccato, etc.) corresponding to the most responsive (resonant) portions of the instrument's responses (e.g., peaks of the analyzed instrument's response) fully breaking in the various parts of the instrument. The applied vibrations are continued until the instrument's amplitude response plateaus.