公开(公告)号：US09883819B2

公开(公告)日：2018-02-06

申请号：US13141048

申请日：2010-01-06

申请人： Marc Jensen ,  Robert Leichner ,  Patrick Beaulieu ,  Kit Yee Au-Yeung ,  Lawrence Arne ,  Mark Zdeblick ,  Andrew Thompson ,  George Savage ,  Timothy Robertson ,  Yashar Behzadi

发明人： Marc Jensen ,  Robert Leichner ,  Patrick Beaulieu ,  Kit Yee Au-Yeung ,  Lawrence Arne ,  Mark Zdeblick ,  Andrew Thompson ,  George Savage ,  Timothy Robertson ,  Yashar Behzadi

IPC分类号： A61B5/07 ,  A61B5/00 ,  G06F19/00 ,  H04B13/00 ,  A61B5/021 ,  A61B5/024 ,  A61B5/11

CPC分类号： A61B5/073 ,  A61B5/0002 ,  A61B5/021 ,  A61B5/024 ,  A61B5/1112 ,  A61B5/486 ,  A61B5/6833 ,  G06F19/00 ,  G06F19/3456 ,  G06F19/3481 ,  G16H10/60 ,  G16H20/00 ,  G16H20/10 ,  H04B13/005

摘要： Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.

公开(公告)号：US08674825B2

公开(公告)日：2014-03-18

申请号：US12404184

申请日：2009-03-13

申请人： Mark Zdeblick ,  Andrew Thompson ,  Aleksandr Pikelny ,  Timothy Robertson

发明人： Mark Zdeblick ,  Andrew Thompson ,  Aleksandr Pikelny ,  Timothy Robertson

IPC分类号： G08B1/08

CPC分类号： A61B5/073 ,  A61B5/0028 ,  A61B5/0031 ,  A61B5/07 ,  A61B5/076 ,  A61B5/1473 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/681 ,  A61B5/6861 ,  A61B5/7282 ,  A61B2560/0214 ,  A61B2560/0462 ,  A61B2562/08 ,  A61B2562/162 ,  A61J3/007 ,  G06F19/00 ,  G06K7/10168 ,  H01Q1/273 ,  Y10T29/49117

摘要： Compositions, systems and methods that allow for the detection of the actual physical delivery of a pharmaceutical agent to a body are provided. Embodiments of the compositions include an identifier and an active agent. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.

摘要翻译： 提供了允许检测药物到身体的实际物理输送的组合物，系统和方法。 组合物的实施方案包括标识符和活性剂。 本发明可用于各种不同的应用，包括但不限于监测治疗方案依从性，跟踪药剂的历史等。

公开(公告)号：US20130190507A1

公开(公告)日：2013-07-25

申请号：US13785504

申请日：2013-03-05

申请人： Rajendra Parasmal JAIN ,  Remy ANGELAUD ,  Andrew Thompson ,  Carol LAMBERSON ,  Scott GREENFIELD

发明人： Rajendra Parasmal JAIN ,  Remy ANGELAUD ,  Andrew Thompson ,  Carol LAMBERSON ,  Scott GREENFIELD

IPC分类号： C07D233/86 ,  C07D235/02

CPC分类号： C07D233/86 ,  C07C231/12 ,  C07C237/30 ,  C07D235/02

摘要： Processes are provided for the synthesis of diarylthiohydantoin and diarylhydantoin compounds. Medicinal products containing the same find particular use in treating prostate cancer, including castration-resistant prostate cancer and/or hormone-sensitive prostate cancer.

摘要翻译： 提供了二芳基硫代乙内酰脲和二芳基乙内酰脲化合物的合成方法。 含有该药物的药物在治疗前列腺癌方面特别有用，包​​括抗阉割前列腺癌和/或激素敏感性前列腺癌。

公开(公告)号：US08469921B2

公开(公告)日：2013-06-25

申请号：US13336956

申请日：2011-12-23

申请人： Timothy Robertson ,  Fataneh Omidvar ,  Yashar Behzadi ,  Lawrence Arne ,  Kenneth Rowberry ,  James Hutchison ,  Robert Leichner ,  George Savage ,  Andrew Thompson ,  Mark Zdeblick ,  Marc Kreidler ,  Hooman Hafezi ,  Robert Duck

发明人： Timothy Robertson ,  Fataneh Omidvar ,  Yashar Behzadi ,  Lawrence Arne ,  Kenneth Rowberry ,  James Hutchison ,  Robert Leichner ,  George Savage ,  Andrew Thompson ,  Mark Zdeblick ,  Marc Kreidler ,  Hooman Hafezi ,  Robert Duck

IPC分类号： A61M5/16

摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.

公开(公告)号：US20110212782A1

公开(公告)日：2011-09-01

申请号：US13124094

申请日：2009-10-14

申请人： Andrew Thompson ,  George Savage ,  Erika Karplus ,  Lawrence Arne ,  Timothy Robertson ,  David O'Reilly

发明人： Andrew Thompson ,  George Savage ,  Erika Karplus ,  Lawrence Arne ,  Timothy Robertson ,  David O'Reilly

IPC分类号： G06F17/00

CPC分类号： A63F13/23 ,  A61B5/02055 ,  A61B5/02405 ,  A61B5/073 ,  A61B5/0816 ,  A61B5/4833 ,  A63F13/02 ,  A63F13/212 ,  A63F2300/1012 ,  A63F2300/6045 ,  G06Q50/00 ,  G07F17/32 ,  G07F17/3206 ,  G07F17/3237

摘要： The present invention provides a receiving device and method for use with gaming pursuits, including, in one aspect, a personal signal receiver to communicate physiologic data, a hub to receive the physiologic data, and a gaming module to receive, directly or indirectly, the physiologic data from the hub.

摘要翻译： 本发明提供了一种用于游戏追求的接收装置和方法，在一个方面，包括个人信号接收器，用于传达生理数据，用于接收生理数据的中枢，以及游戏模块，用于直接或间接接收 来自集线器的生理数据。

公开(公告)号：US20100312188A1

公开(公告)日：2010-12-09

申请号：US12673326

申请日：2009-12-15

申请人： Timothy Robertson ,  Fataneh Omidvar ,  Yashar Behzadi ,  Lawrence Arne ,  Kenneth Rowberry ,  James Hutchison ,  Robert Leichner ,  George Savage ,  Andrew Thompson ,  Mark Zdeblick ,  Marc Kreidler ,  Hooman Hafezi ,  Robert Duck

发明人： Timothy Robertson ,  Fataneh Omidvar ,  Yashar Behzadi ,  Lawrence Arne ,  Kenneth Rowberry ,  James Hutchison ,  Robert Leichner ,  George Savage ,  Andrew Thompson ,  Mark Zdeblick ,  Marc Kreidler ,  Hooman Hafezi ,  Robert Duck

IPC分类号： A61M5/20 ,  A61B5/00

CPC分类号： A61M5/1723 ,  A61B5/0006 ,  A61B5/0028 ,  A61B5/02055 ,  A61B5/0404 ,  A61B5/04085 ,  A61B5/0428 ,  A61B5/053 ,  A61B5/11 ,  A61B5/1112 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/4094 ,  A61B2560/0209 ,  A61B2560/0412 ,  A61B2560/0468 ,  A61B2562/0219 ,  A61M5/1452 ,  A61M5/172 ,  G06F19/34 ,  G06F19/3418 ,  H04B13/005

摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.

摘要翻译： 提供可能是外部或可植入的接收器。 本发明的接收机的方面包括存在一个或多个：高功率低功率模块; 中介模块; 电源模块，被配置为激活和去激活一个或多个电源给高功率处理块; 连接主站和从站的串行外设接口总线; 和多用途连接器。 本发明的接收机可以被配置为接收电传送的信号。 还提供了包括接收器的系统，以及使用它们的方法。 另外公开了使用接收器来配合给药系统的系统和方法。

公开(公告)号：US07737306B2

公开(公告)日：2010-06-15

申请号：US12255951

申请日：2008-10-22

申请人： Andrew Thompson ,  Shawn Zhang ,  Lonnie Robarge

发明人： Andrew Thompson ,  Shawn Zhang ,  Lonnie Robarge

IPC分类号： C07C45/00

CPC分类号： C07C45/42 ,  C07C29/44 ,  C07C29/58 ,  C07C41/48 ,  C07C41/56 ,  C07C45/29 ,  C07C45/515 ,  C07C47/14 ,  C07C47/222 ,  C07C43/313 ,  C07C43/303

摘要： One or more embodiments of the invention are directed to the synthetic methods for making lepidopteran pheromones including navel orangeworm pheromones. The synthetic methods involve novel, efficient, and environmentally benign steps and procedures.

摘要翻译： 本发明的一个或多个实施方案涉及用于制备鳞翅目信息素的合成方法，包括脐橙交感神经元信息素。 合成方法涉及新颖，有效和环境友好的步骤和程序。

公开(公告)号：US07213420B2

公开(公告)日：2007-05-08

申请号：US10290369

申请日：2002-11-08

申请人： Justin Lynch ,  Maria Bourke ,  Andrew Thompson

发明人： Justin Lynch ,  Maria Bourke ,  Andrew Thompson

IPC分类号： D04B9/46

CPC分类号： D04B1/108 ,  A41B11/005 ,  A41B17/005 ,  A41B2400/34 ,  D04B1/16 ,  D04B1/26 ,  D04B9/40 ,  D04B15/02 ,  D10B2321/042 ,  D10B2401/021 ,  D10B2401/022 ,  D10B2401/13 ,  D10B2403/023

摘要： A knitted sock has an inner layer 2 comprising a toe end 4 and an outer layer 3 comprising a toe end 7. The inner and outer toe ends are aligned and joined wale stitch to wale stitch to form a composite toe end, which is closed to provide a flat toe seam 10. The layered sock is manufactured complete in a single process being knit continuously from the inner toe end to the outer toe end. It comprises reciprocated heel and toe portions. The foot portion of the inner layer is knit from a yarn with properties such as a low coefficient of friction and/or antifungal/antibacterial properties. The low friction fiber is a fluoropolymer such as polytetrafluroethylene. The outer layer may comprise a cushion structure.

摘要翻译： 针织袜具有包括趾端4的内层2和包括趾端7的外层3。 内端和外脚趾端部对齐并连接起来，将纵向线迹连接到纵向线迹以形成复合脚趾端，该端部被封闭以提供平坦的趾部接缝10。 分层的袜子在一个单一的过程中被制造成完整的，从内趾端连续地编织到外趾端。 它包括往复运动的跟部和脚趾部分。 内层的脚部由具有低摩擦系数和/或抗真菌/抗菌性能的纱线编织而成。 低摩擦纤维是聚四氟乙烯等含氟聚合物。 外层可以包括缓冲结构。

公开(公告)号：US20060040334A1

公开(公告)日：2006-02-23

申请号：US10510246

申请日：2003-04-04

申请人： Andrew Thompson

发明人： Andrew Thompson

IPC分类号： C12Q1/37 ,  G01N33/00

CPC分类号： G01N33/6848 ,  C07K1/13 ,  G01N33/6851

摘要： Provided is a method for characterising an analyte by matrix assisted laser desorption ionisation (MALDI) mass spectrometry, which method comprises: (a) labelling the analyte with a light-absorbing label that absorbs light at a pre-determined frequency, to form a labelled analyte; (b) embedding the labelled analyte in a matrix formed from at least one compound that absorbs light, to form an embedded labelled analyte; (c) desorbing the embedded labelled analyte by exposing it to light having the pre-determined frequency, to form a desorbed analyte; and (d) detecting the desorbed analyte by mass spectrometry to characterise the analyte.

摘要翻译： 提供了一种通过基质辅助激光解吸电离（MALDI）质谱鉴定分析物的方法，该方法包括：（a）用预吸收光的光吸收标记物以预定的频率标记分析物，形成标记的 分析物; （b）将标记的分析物包埋在由吸收光的至少一种化合物形成的基质中，以形成嵌入的标记分析物; （c）通过将嵌入的标记分析物暴露于具有预定频率的光来解吸，形成解吸附的分析物; 和（d）通过质谱检测解吸附的分析物来表征分析物。

公开(公告)号：US5470630A

公开(公告)日：1995-11-28

申请号：US283031

申请日：1994-07-29

申请人： Andrew Thompson

发明人： Andrew Thompson

IPC分类号： C08K3/34 ,  C08L95/00 ,  D06N7/00

CPC分类号： C08L95/00 ,  C08K3/346 ,  D06N7/0071 ,  D06N7/0076 ,  D06N2203/042 ,  D06N2203/08 ,  D06N2205/20 ,  D06N2209/041 ,  D06N2209/1628 ,  D06N2211/066 ,  Y10S524/914 ,  Y10S524/915 ,  Y10T428/23979 ,  Y10T428/23986 ,  Y10T428/23993 ,  Y10T428/31815 ,  Y10T442/20 ,  Y10T442/2369 ,  Y10T442/2418 ,  Y10T442/2738 ,  Y10T442/3707

摘要： A floor covering having a bitumen composition as a backing layer, such as carpet tiles, which bitumen composition comprises straight run bitumen and a mixture of high density and low density polyethylene polymers blended and dispersed in the straight run bitumen as a continuous phase in an amount of up to about 12% by weight and which bitumen composition contains a minimum of about 40% by weight of a mineral filler material, such as limestone, and the bitumen composition having improved dimensional stability, adhesion, static loading and electrical conductivity and having lower cost and processing advantages.

摘要翻译： 一种具有沥青组合物作为背衬层的地板覆盖物，例如地毯砖，该沥青组合物包含直沥青和高密度和低密度聚乙烯聚合物的混合物，其以直线沥青混合和分散为连续相的量 至多约12重量％，并且哪个沥青组合物含有至少约40重量％的矿物填料材料，例如石灰石，并且沥青组合物具有改善的尺寸稳定性，粘合力，静载荷和导电性并且具有较低的 成本和加工优势。