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    Functionally graded biocompatible coating and coated implant
    21.
    发明授权
    Functionally graded biocompatible coating and coated implant 有权
    功能分级的生物相容性涂层和涂层植入物

    公开(公告)号：US08491936B2

    公开(公告)日：2013-07-23

    申请号：US11082180

    申请日：2005-03-16

    Applicant: Afsaneh Rabiei ,  Jerome J. Cuomo ,  Brent C. Thomas

    Inventor： Afsaneh Rabiei ,  Jerome J. Cuomo ,  Brent C. Thomas

    IPC: A61F2/00 ,  A61K9/16

    CPC classification number: A61L27/32 ,  A61C8/0012 ,  A61C8/0013 ,  A61F2/0077 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2002/30028 ,  A61F2002/30029 ,  A61F2002/30929 ,  A61F2002/3098 ,  A61F2250/0051 ,  A61F2310/00796

    Abstract: The present invention provides a biocompatible coating comprising calcium phosphate that is functionally graded across the thickness of the coating. The coating, which preferably includes hydroxyapatite, is particularly useful for coating implants, such as dental or orthopedic implants. The functionally graded coating is generally crystalline near the interface with the surface of the implant, with crystallinity and crystal diameter decreasing toward the outer layer of the coating. The invention further provides methods for preparing a coated implant comprising a functionally graded calcium phosphate coating thereon.

    Abstract translation: 本发明提供一种生物相容性涂层，其包含在功能上分级穿过涂层厚度的磷酸钙。 优选包括羟基磷灰石的涂层对于涂覆植入物例如牙科或矫形植入物是特别有用的。 功能梯度涂层在与植入物表面的界面附近通常是结晶的，结晶度和晶体直径朝着涂层的外层减小。 本发明进一步提供了制备涂覆植入物的方法，其中包括其上功能性梯度的磷酸钙涂层。

    Modular basal thumb joint implant
    22.
    发明授权
    Modular basal thumb joint implant 有权
    模块化基底拇指关节植入物

    公开(公告)号：US08021431B1

    公开(公告)日：2011-09-20

    申请号：US10758455

    申请日：2004-01-15

    Applicant: Charles O. Townley

    Inventor： Charles O. Townley

    IPC: A61F2/42

    CPC classification number: A61F2/4241 ,  A61F2002/30011 ,  A61F2002/30029 ,  A61F2002/30112 ,  A61F2002/30172 ,  A61F2002/30299 ,  A61F2002/30332 ,  A61F2002/3092 ,  A61F2002/4258 ,  A61F2310/00413

    Abstract: Basal thumb joint implant has a head with a smooth, generally hemispherical, medio-proximally directed, articulating surface, and a generally abrupt, distally directed, truncation thereto; and a stem attached to the head, which arises from the truncation of the head and includes at least one of the following features: A) a general angle of attachment to the head which is acute in relation to the truncation of the head; B) a flanged cross-sectional stem profile; C) an inwardly curved stem; D) an eccentric head attachment site for the stem. The implant may be one-piece or modular in construction. The modular basal thumb joint implant, however, which is not necessarily limited by requiring inclusion of the aforesaid additional features A-D, includes a head with a smooth, generally hemispherical, medio-proximally directed, articulating surface, a generally abrupt, distally directed truncation thereto, and a stem trunion-receiving cup in the truncation; and a stem attachable to the head, which stem has intracarpal spike-like distal end, and a proximally directed trunion, which trunion is insertable into the stem trunion-receiving cup of the head. Other digits may be provided with analogous implants, particularly with respect to those digital implants amenable to modularity.

    Abstract translation: 基底拇指关节植入件具有头部，其具有平滑的，大致半球形的中内向近端定向的关节表面，并且具有大致突然的，远端的截短; 以及附接到头部的杆，其由头部的截断产生，并且包括以下特征中的至少一个：A）与头部的相对于头部的截断是急性的一般的附接角度; B）带法兰的横截面茎型; C）向内弯曲的杆; D）用于茎的偏心头部附着部位。 植入物可以是一体的或模块化的结构。 然而，模块化基础拇指关节植入物不一定受到要求包含上述附加特征AD的限制，包括具有平滑的，大体上半球形的中内向近端定向的关节表面的头部，其通常突然，远端定向的截肢 ，和一个茎组合接收杯在截断; 以及可附接到头部的杆，所述头部具有棘爪状尖端远端，以及近端指向的团块，该组合体可插入头部的茎组合容纳杯中。 其他数字可能具有类似的植入物，特别是对于适合于模块化的那些数字植入物。

    Anti-adhesion membrane
    23.
    发明授权
    Anti-adhesion membrane 有权
    防粘膜

    公开(公告)号：US07833284B2

    公开(公告)日：2010-11-16

    申请号：US11823048

    申请日：2007-06-26

    Applicant: Isador H. Lieberman

    Inventor： Isador H. Lieberman

    IPC: A61F2/02

    CPC classification number: A61F2/00 ,  A61B17/58 ,  A61B17/70 ,  A61F2/0077 ,  A61F2/30767 ,  A61F2/442 ,  A61F2002/30029

    Abstract: A membrane for implantation into a patient includes a first layer and a second layer. The first layer has oppositely disposed outer and inner first layer surfaces. The second layer has oppositely disposed outer and inner second layer surfaces. The second layer is at least partially attached to the first layer with the inner first and second layer surfaces adjacent one another. The inner first and second layer surfaces are resistant to biological tissue ingrowth and the outer first and second layer surfaces are conducive to biological tissue ingrowth.

    Abstract translation: 用于植入患者的膜包括第一层和第二层。 第一层具有相对设置的外部和内部第一层表面。 第二层具有相对设置的外部和第二层表面。 第二层至少部分地附接到第一层，内部第一和第二层表面彼此相邻。 内部第一和第二层表面抵抗生物组织向内生长，并且外部第一和第二层表面有利于生物组织向内生长。

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