摘要:
A reagent tube configured with a stellated shaped pattern, on its bottom interior surface, configured to facilitate complete or near-complete withdrawal of fluid from the tube, via a pipette tip. The reagent tube may be used for transporting reagents and for carrying out processing operations on biological samples with the reagents, such as preparing polynucleotides extracted from the sample for amplification.
摘要:
A device for creating a microfluidic channel structure includes two plates forming a chamber between the two plates. The chamber has at least one inlet for feeding a fluid into the chamber and at least one outlet for discharging the fluid out of the chamber. A cooling element is associated with at least one of the two plates for converting fluid disposed in the chamber into a solid. A plurality of heating elements is associated with at least a first of the two plates and distributed so as to provide, by a heating up of some of the heating elements so as to convert areas of the solid that are in a vicinity of the heating elements to the fluid, a channel structure leading from the at least one inlet through the chamber to the at least one outlet. The channel structure is configured to convey fluid flow.
摘要:
Methods for measuring biochemical reactions and analysis of reaction products by controlling dispersion of reagents within fluid streams such that the measuring of the biochemical reaction is substantially free of a measurable dispersion artifact. Controlling dispersion of reagents within fluid streams can include flowing multiple fluid streams each including reaction reagents into contact through a mixing region to laterally mix the fluid streams and then passing the merged, laterally mixed fluid stream through a controlled dispersion element to axially disperse the reaction reagents merged fluid stream. Controlling dispersion of reagents within fluid streams can include controlling flow rates of multiple fluid streams each including reaction reagents to create a concentration gradient that is substantially free of a measurable dispersion artifact. The biochemical reaction can occur in a microfluidic chip.
摘要:
The present technology provides for an apparatus for detecting polynucleotides in samples, particularly from biological samples. The technology more particularly relates to microfluidic systems that carry out PCR on nucleotides of interest within microfluidic channels, and detect those nucleotides. The apparatus includes a microfluidic cartridge that is configured to accept a plurality of samples, and which can carry out PCR on each sample individually, or a group of, or all of the plurality of samples simultaneously.
摘要:
A micro-machined temperature dependent one-shot valve is provided which has an operation temperature adjustable readily, causing no leakage below the operation temperature even at a high pressure difference, being useful both in a liquid environment and in a gas environment, and being miniaturizable. The micro-machined temperature dependent one-shot valve comprises a silicon substrate 100, a channel 101 penetrating the entire thickness of the silicon substrate, and a low melting point metal member 101 deposited on one face of the silicon substrate to obstruct the channel.
摘要:
Provided are an apparatus and a method of controlling a microfluidic system, and the microfluidic system. The apparatus of controlling the microfluidic system includes a central control block controlling an operation of the microfluidic system, a rotator control block controlling a rotator, a position control block controlling the position of a moving unit, the moving unit moving to a position of the microfluidic structure, and a radiation energy source control block controlling energy of a radiation energy source, the radiation energy source using an electromagnetic wave to scan over a position of the microfluidic structure. Such a configuration allows effective control of a miniaturized portable microfluidic system.
摘要:
Provided are a valve unit and a reaction apparatus having the valve unit. The valve unit includes a phase transition material, which melts and expands upon an application of the electromagnetic waves to the valve filler, and the valve filler is directed into the channel through the connection passage and closes the channel. The valve unit also includes heat generation particles, which are dispersed in the phase transition material and generate heat upon an application of electromagnetic wave energy.
摘要:
Fluidic flow is directed in a capillary or channel in a miniaturized separation or microfluidic device by the addition of liquid crystals to the fluid filling the channel. The liquid crystal medium undergoes changes in morphology upon the addition of external stimuli (magnetic and/or electric field and temperature). Under appropriate conditions this externally triggered change in liquid crystal produces a change in viscosity. This triggered change in viscosity directs fluid flow in multiple path channels and/or capillaries and therefore serves as a means of directing and controlling fluid flow within a capillary or channel in a miniaturized separation or microfluidic device.
摘要:
An electro-hydraulic valve apparatus includes a flow channel, a hydraulic control channel defining an electro-hydraulic valve junction where the hydraulic control channel is adjacent to the flow channel, a flexible wall between the flow channel and the hydraulic control channel at the electro-hydraulic valve junction, and Peltier devices adjacent to the hydraulic control channel on opposite sides of the electro-hydraulic valve junction for controllably applying a hydraulic force against the flexible wall repositioning the flexible wall in relation to the flow channel to selectively close or open the electro-hydraulic valve apparatus.