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104 条记录 (耗时 0.04 秒)

    Implant retaining device
    35.
    发明授权
    Implant retaining device 有权
    植入物保持装置

    公开(公告)号：US08672980B2

    公开(公告)日：2014-03-18

    申请号：US12861902

    申请日：2010-08-24

    申请人： John W. Morris ,  Lawrence A. Shimp ,  David R. Kaes

    发明人： John W. Morris ,  Lawrence A. Shimp ,  David R. Kaes

    IPC分类号： A61B17/70

    CPC分类号： A61B17/7059 ,  A61B17/80 ,  A61B17/86 ,  A61B2017/00831 ,  A61F2/28 ,  A61F2/30749 ,  A61F2/442 ,  A61F2/4455 ,  A61F2/446 ,  A61F2/447 ,  A61F2002/2817 ,  A61F2002/30794 ,  A61F2220/0008 ,  A61F2310/00179 ,  A61F2310/00359

    摘要： There is provided an implant retaining device, which has the effect of preventing an intervertebral implant from jutting out of the receiving bed. The implant retaining device generally includes a plate having at least one throughbore to receive a screw, and a screw for securing the plate to the vertebrae. The plate may be dimensioned to cover a portion of the opening of a receiving bed, and thus, need only be secured to a single vertebral body. In an alternate embodiment, the plate may be used during bone fracture correction procedures to prevent a bone screw from backing out of engagement with adjacent bone sections. A method of retaining an intervertebral implant using the device is also provided.

    摘要翻译： 提供了一种植入物保持装置，其具有防止椎间植入物从接受床突出的作用。 植入物保持装置通常包括具有至少一个通孔以容纳螺钉的板和用于将板固定到椎骨的螺钉。 该板的尺寸可以确定为覆盖接收床的开口的一部分，因此仅需要固定到单个椎体。 在替代实施例中，可以在骨折矫正程序期间使用该板，以防止骨螺钉脱离与相邻骨段的接合。 还提供了使用该装置保持椎间植入物的方法。

    FENESTRATED WOUND REPAIR SCAFFOLD
    37.
    发明申请
    FENESTRATED WOUND REPAIR SCAFFOLD 有权
    复合伤口修复SCAFFOLD

    公开(公告)号：US20110262515A1

    公开(公告)日：2011-10-27

    申请号：US12766494

    申请日：2010-04-23

    申请人： Nels Lauritzen ,  Lawrence A. Shimp ,  Brent Mitchell

    发明人： Nels Lauritzen ,  Lawrence A. Shimp ,  Brent Mitchell

    IPC分类号： A61F2/02 ,  A61P17/02

    CPC分类号： A61L27/60 ,  A61K38/39 ,  A61L27/24 ,  A61L27/56

    摘要： Fenestrated wound repair scaffolds and methods for forming scaffolds involve dispersing human collagen having a preserved amount of native constituents in solution, depositing the human collagen dispersion in a tray, forming openings in the collagen dispersion and removing the liquid component to form a fenestrated wound repair scaffold. Fenestrated wound repair scaffolds include a network of openings passing linearly through the wound repair scaffold to form channels for cells to pass into so as to form a series of cell formations therein.

    摘要翻译： 开窗修复支架和形成支架的方法包括将具有保留量的天然成分的人胶原分散在溶液中，将人胶原分散体沉积在托盘中，在胶原分散体中形成开口并除去液体组分以形成开窗伤口修复支架 。 开窗伤口修复支架包括通过伤口修复支架线性通过的开口网，以形成细胞通过的通道，以在其中形成一系列细胞结构。

    Tissue pathogen inactivation/removal process
    39.
    发明授权
    Tissue pathogen inactivation/removal process 有权
    组织病原体灭活/去除过程

    公开(公告)号：US07585461B2

    公开(公告)日：2009-09-08

    申请号：US10766614

    申请日：2004-01-28

    申请人： Lawrence A. Shimp ,  Sheldon Dean ,  Daniel Martins

    发明人： Lawrence A. Shimp ,  Sheldon Dean ,  Daniel Martins

    IPC分类号： A61L2/18

    CPC分类号： A61L2/0088 ,  A61F2/28 ,  A61F2002/2835 ,  A61F2002/302 ,  A61F2002/4646 ,  A61F2002/4649 ,  A61F2230/0065 ,  A61L2/0011

    摘要： Bone such as cortical or cancellous bone or connective tissue are centrifuged as a solution is applied to the tissue in a continuous process. The centrifuge creates forces, which cause the flowing solution to penetrate substantially all of the cavities of the tissue. The solution, which may be alcohol, a detergent, an oxidizer, or a surfactant, with or without water, flushes the cavities of the tissue and removes and inactivates viral and bacterial contaminants. In a second embodiment, bone or connective tissue is centrifuged in a batch process to remove contaminants from cavities in the tissue by first spinning the tissue dry and then submerging the tissue in a viral/bacteria cleansing solution and centrifuging the submerged tissue and solution at a sufficiently high speed and radius from the spin axis to create substantially high G forces on the tissue and solution to force the solution into and through the tissue cavities. The solution with the flushed contaminants is then removed from the vicinity of the tissue. In a further embodiment, an enzyme is centrifuged with the tissue to digest lipids and proteins which are then removed with a flushing solution which may also inactivate viral and bacterial contaminants. In yet a further embodiment, the centrifuge can be used to infuse biologically and/or structurally useful materials into the tissue. Further, the lipids and proteins may be removed by a chemically active agent such as oxo anions.

    摘要翻译： 将骨骼如皮层或松质骨或结缔组织离心，将溶液以连续方式施用于组织。 离心机产生力，这使得流动的溶液基本上穿透组织的所有空腔。 溶液，其可以是醇，洗涤剂，氧化剂或表面活性剂，具有或不具有水，冲洗组织的空腔并去除和灭活病毒和细菌污染物。 在第二个实施方案中，将骨或结缔组织以分批方法离心以通过首先将组织干燥并然后将组织浸没在病毒/细菌清洁溶液中并从而将浸没的组织和溶液离心 从旋转轴线到足够高的速度和半径，以在组织和溶液上产生基本上高的G力，以迫使溶液进入和穿过组织腔。 然后从组织的附近去除具有冲洗的污染物的溶液。 在另一个实施方案中，将酶与组织离心以消化脂质和蛋白质，然后用​​冲洗溶液除去，所述冲洗溶液也可能使病毒和细菌污染物失活。 在又一个实施例中，离心机可用于将生物和/或结构上有用的材料注入组织。 此外，脂质和蛋白质可以通过化学活性剂如氧阴离子去除。