公开(公告)号：US20100014156A1

公开(公告)日：2010-01-21

申请号：US12438994

申请日：2007-08-08

Applicant: Yoshinori Iketaki

Inventor： Yoshinori Iketaki

IPC: G02B21/06

CPC classification number: G02B21/16 ,  G01N21/6458 ,  G01N2021/6415 ,  G01N2201/06113 ,  G01N2201/104 ,  G01N2201/1053 ,  G02B5/20 ,  G02B5/3083 ,  G02B21/002 ,  G02B26/06 ,  G02B2207/113

Abstract: A microscope for observing a sample containing a substance having at least two excited quantum states includes a pump light source 21 for emitting pump light, an erase light source 22 for emitting erase light, a light combining section 23 to 26 for coaxially combining the pump light and the erase light, a light collecting section 62 for collecting the combined lights, a scanning section 44 and 45 for scanning the sample with the combined lights, a detecting section 50 for detecting photoresponsive signals generated from the sample, a wavelength selecting element 42 arranged in the light path of the combined lights and provided with an erase light selecting region having a high wavelength selectivity for the erase light and with a pump light selecting region having a high wavelength selectivity for the pump light, and a space modulating element 43 arranged in the light path of the combined lights for spatially modulating the erase light corresponding to the erase light selecting region of the wavelength selecting element.

Abstract translation: 用于观察含有具有至少两个激发量子态的物质的样品的显微镜包括用于发射泵浦光的泵浦光源21，用于发射擦除光的擦除光源22，用于同时组合泵浦光的光合成部23至26 擦除光，用于收集组合光的光收集部分62，用于组合光扫描样本的扫描部分44和45;检测部分50，用于检测从样本产生的光响应信号;波长选择元件42，被布置 在组合光的光路中设置有对于擦除光具有高波长选择性的擦除光选择区域和对泵浦光具有高波长选择性的泵浦光选择区域，以及空间调制元件43，其布置在 用于空间调制对应于擦除光选择区域的擦除光的组合光的光路 的波长选择元件。

公开(公告)号：US20090087080A1

公开(公告)日：2009-04-02

申请号：US12266437

申请日：2008-11-06

Applicant: Woo Jung Ahn ,  Jung Hwan Kim ,  Hee Wook You

Inventor： Woo Jung Ahn ,  Jung Hwan Kim ,  Hee Wook You

IPC: G06K9/00

CPC classification number: G01N21/88 ,  G01N21/8901 ,  G01N21/8903 ,  G01N2201/104

Abstract: A vision inspection system and a workpiece inspection method are used in inspecting a workpiece. The vision inspection system includes a level block having an upper surface whose opposite end regions are defined as a first position and a second position. A first transfer device has a table for supporting the workpiece. The first transfer device is installed on the upper surface of the level block for rectilinearly moving the table between the first position and the second position. A camera is arranged above the level block for taking an image of the workpiece to output image data. A second transfer device is installed on the upper surface of the level block for rectilinearly moving the camera between the first position and the second position. A computer is connected to the first transfer means, the camera and the second transfer means to control them in a specified manner.

Abstract translation: 在检查工件时使用视觉检查系统和工件检查方法。 视觉检查系统包括具有上表面的水平块，其相对的端部区域被定义为第一位置和第二位置。 第一传送装置具有用于支撑工件的工作台。 第一传送装置安装在水平块的上表面上，用于在第一位置和第二位置之间直线移动工作台。 摄像机布置在水平块上方，用于拍摄工件的图像以输出图像数据。 第二传送装置安装在水平块的上表面上，用于在第一位置和第二位置之间直线地移动照相机。 计算机连接到第一传送装置，照相机和第二传送装置，以指定方式控制它们。

公开(公告)号：US20030143637A1

公开(公告)日：2003-07-31

申请号：US10233322

申请日：2002-08-30

Inventor： Gowri Pyapali Selvan ,  John Francis Gordon ,  Karen Jean Brazil ,  Joseph Roby Iringan Urcia

IPC: G01N033/53 ,  G01N033/542 ,  G06F019/00 ,  G01N033/48 ,  G01N033/50 ,  C12M001/34

CPC classification number: G01N21/55 ,  B01L3/5027 ,  G01N15/1475 ,  G01N21/07 ,  G01N21/253 ,  G01N21/59 ,  G01N21/5911 ,  G01N33/54306 ,  G01N33/54353 ,  G01N33/54386 ,  G01N35/00069 ,  G01N2015/1486 ,  G01N2021/0325 ,  G01N2021/1742 ,  G01N2021/551 ,  G01N2021/5915 ,  G01N2201/104

Abstract: A clinical diagnostic assay is performed on an optical bio disc and is read with a disc drive. More specifically this invention relates to capture layer assemblies for cellular assays using optical bio-discs. The current invention includes methods for determining the quality and quantity of a specific type of cell in a biological sample. These methods includes binding capture agents to a capture zone on the disc, providing a sample to the capture zone, remove portions of the sample that are not bound in the capture zone, and counting bound cells. The current invention also includes methods and apparatus for performing a cluster designation marker assay using an optical disc and disc drive and method for making optical analysis discs for performing such cluster designation assays.

Abstract translation: 在光学生物盘上进行临床诊断测定，并用盘驱动器读取。 更具体地，本发明涉及使用光学生物盘的细胞测定的捕获层组件。 本发明包括用于确定生物样品中特定类型的细胞的质量和数量的方法。 这些方法包括将捕获剂结合到盘上的捕获区，向捕获区提供样品，去除未结合在捕获区中的样品部分，并计数结合的细胞。 本发明还包括使用光盘和盘驱动器执行簇指定标记测定的方法和装置以及用于制造用于进行这种簇指定测定的光学分析盘的方法。

公开(公告)号：US4824250A

公开(公告)日：1989-04-25

申请号：US191744

申请日：1988-05-05

Applicant: John W. Newman

Inventor： John W. Newman

IPC: G01N21/88 ,  G01N29/04

CPC classification number: G01N21/88 ,  G01N2021/1759 ,  G01N2201/104

Abstract: The invention provides a method and apparatus for non-destructive testing of bonded structures, such as laminated or composite materials. A beam of coherent light is directed successively onto each point of the object. The reflected beam creates a speckle pattern. The pattern is observed once while the object is stationary and once while the object is mechanically excited. If the point being observed is free of defects, the speckle pattern will be substantially unaffected by the vibration of the excited object. If the point is defective, vibration will blur the speckle pattern. The entire object is scanned, point by point, and the results of the comparison of the speckle patterns obtained for each point are stored and displayed. In another embodiment, the object is made to vibrate continuously, and the apparatus determines whether the speckle pattern is sharp or blurred, for each point being scanned. The sharpness of the speckle pattern can be inferred from the measured intensity of the speckle pattern, or it can be calculated directly by a suitable algorithm. In general, if the detector has a nonlinear response characteristic, the total intensity of the speckle pattern will be lower when the pattern is blurred, and higher when the pattern is sharp. A low intensity therefore indicates that the point on the object is defective. As in the first embodiment, the results of the analysis are stored in a computer memory and displayed on a video monitor.

Abstract translation: 本发明提供了一种用于粘结结构如层压或复合材料的非破坏性测试的方法和装置。 一束相干光连续地指向物体的每个点。 反射光束产生斑点图案。 当物体静止时观察一次，一旦物体被机械激发，就会观察到该图案。 如果观察点没有缺陷，则斑点图案将基本上不受被激发物体的振动的影响。 如果点有缺陷，振动会使斑点图案模糊。 逐点扫描整个物体，并存储并显示每个点获得的斑点图案的比较结果。 在另一个实施例中，使物体连续地振动，并且该装置确定斑点图案是否锐利或模糊，对于每个被扫描的点。 斑点图案的清晰度可以从斑点图案的测量强度推断出来，或者可以通过适当的算法直接计算。 通常，如果检测器具有非线性响应特性，则当图案模糊时，斑点图案的总强度将较低，并且当图案清晰时，散斑图案的总强度将较低。 因此，低强度表示物体上的点有缺陷。 与第一实施例一样，分析结果存储在计算机存储器中并显示在视频监视器上。

公开(公告)号：US4568835A

公开(公告)日：1986-02-04

申请号：US438468

申请日：1982-11-02

Applicant: Kazunori Imamura ,  Akikazu Tanimoto ,  Nobutoshi Abe

Inventor： Kazunori Imamura ,  Akikazu Tanimoto ,  Nobutoshi Abe

IPC: G03B27/32 ,  G01N21/88 ,  G01N21/94 ,  G01N21/956 ,  H01L21/027 ,  H01L21/66

CPC classification number: G01N21/94 ,  G01N21/956 ,  G01N2201/0642 ,  G01N2201/104

Abstract: An apparatus for detecting foreign matter present on a planar substrate comprises apparatus for scanning the surface of the substrate with an oblique incident light beam, apparatus for photo-electrically detecting the scattered light generator in the trajectory of the light beam scanning on the substrate, and apparatus for eliminating stray light unnecessary for the foreign matter detection.

Abstract translation: 用于检测存在于平面基板上的异物的装置包括：用斜入射光束扫描基板的表面的装置，用于在基板上的光束扫描的轨迹中对散射光发生器进行光电检测的装置;以及 用于消除异物检测所不需要的杂散光的装置。

公开(公告)号：US11793207B2

公开(公告)日：2023-10-24

申请号：US17429478

申请日：2019-09-30

Applicant: Nordischer Maschinenbau Rud. Baader GmbH + Co. KG

Inventor： Adrian Schulze

IPC: A22C21/00 ,  G01N21/84

CPC classification number: A22C21/003 ,  A22C21/0053 ,  G01N21/84 ,  G01N2201/104

Abstract: An apparatus for automatically recovering breast fillets from poultry bodies or parts thereof has a conveying device to continuously convey the poultry bodies in a conveying direction. The conveying device has receiving elements to hold and convey the poultry bodies along a processing path. Processing stations are arranged on the processing path and the stations include at least a furcula-removal station and a breast fillet detaching station. At least one measuring device is arranged on the processing path downstream of the breast fillet detaching station. The poultry bodies held by the receiving elements are conveyed past the measuring device such that the sternum of the poultry bodies is oriented at least substantially transversely to the conveying direction with the breast side facing the measuring device. The measuring device has a scanning element to mechanically scan the poultry bodies on the breast side. A corresponding method is also provided.

公开(公告)号：US09891175B2

公开(公告)日：2018-02-13

申请号：US14982747

申请日：2015-12-29

Applicant: KLA-Tencor Corporation

Inventor： Jamie M. Sullivan ,  Yevgeniy Churin

IPC: G01N21/00 ,  G01N21/88 ,  G01N21/95 ,  G02F1/33 ,  G02B27/10 ,  G02B27/12 ,  G02B26/10

CPC classification number: G01N21/8806 ,  G01N21/9501 ,  G01N2201/0635 ,  G01N2201/104 ,  G01N2201/105 ,  G01N2201/106 ,  G02B26/101 ,  G02B27/1086 ,  G02B27/123 ,  G02F1/33

Abstract: A system to generate multiple beam lines in an oblique angle multi-beam spot scanning wafer inspection system includes a beam scanning device configured to scan a beam of illumination, an objective lens oriented at an oblique angle relative to the surface of a sample and with an optical axis perpendicular to a first scanning direction on the sample, and one or more optical elements positioned between the objective lens and the beam scanning device. The one or more optical elements split the beam into two or more offset beams such that the two or more offset beams are separated in a least a second direction perpendicular to the first direction. The one or more optical elements further modify the phase characteristics of the two or more offset beams such that the two or more offset beams are simultaneously in focus on the sample during a scan.

公开(公告)号：US20170030842A1

公开(公告)日：2017-02-02

申请号：US15105479

申请日：2013-12-27

Applicant: Sensofar Medical, S.L.

Inventor： Ferran LAGUARTA BERTRAN ,  Carlos Bermudez Porras ,  Roger Artigas Pursals ,  Cristina Cadevall Artigues

IPC: G01N21/952 ,  G01B11/06 ,  G01B11/24 ,  G01N21/954

CPC classification number: G01N21/952 ,  A61F2/82 ,  A61F2240/008 ,  G01B11/0675 ,  G01B11/2408 ,  G01N21/954 ,  G01N2201/062 ,  G01N2201/101 ,  G01N2201/104

Abstract: The device has an apparatus for rotatably holding and positioning at least one stent-like object and a unit for illuminating at least inner and outer surfaces thereof, including at least a wide field epi illumination device and a diffuse back illumination device for simultaneously illuminating the stent-like object. The illumination unit may further include diffuse side illumination device for inspecting side surfaces of the stent-like object. An apparatus for acquiring images of the stent-like object including at least one microscope objective lens and at least one camera is also provided.

Abstract translation: 该装置具有用于可旋转地保持和定位至少一个支架状物体的装置和用于至少照射其内表面和外表面的单元，该装置包括至少一个宽视野外照明装置和漫反射照明装置，用于同时照射支架 类物体 照明单元还可以包括用于检查支架状物体的侧表面的漫射侧照明装置。 还提供了一种用于获取包括至少一个显微镜物镜和至少一个照相机的支架样物体的图像的设备。

公开(公告)号：US09557284B2

公开(公告)日：2017-01-31

申请号：US14653001

申请日：2013-12-18

Applicant: Commissariat A L'Energie Atomique et Aux Energies Alternatives

Inventor： Rene Vogler

IPC: G01N23/203 ,  H04N5/32 ,  H04N5/33 ,  G01N23/04 ,  G21K1/02 ,  G01N21/59 ,  G01N21/47 ,  G21K1/04

CPC classification number: G01N23/203 ,  G01N21/47 ,  G01N21/59 ,  G01N23/04 ,  G01N2201/104 ,  G01N2223/314 ,  G01N2223/3301 ,  G01N2223/335 ,  G21K1/02 ,  G21K1/043 ,  H04N5/32 ,  H04N5/33

Abstract: A scanning illuminating device includes an emission center from which radiation is emitted in an illuminating sector. A cylindrical ring is centered on the source and is rotatably movable about a first axis. The ring includes a plurality of slits regularly distributed about its axis of rotation and having the same angular amplitude α. A cylinder portion is centered on the source and is rotatably movable about a second axis crossing the first axis at the center and forming a nonzero angle therewith. The cylinder portion includes a slit having an angular amplitude β. A first device control of the rotation of the ring, defining an elementary angular step as such that an integer N1 other than 1 meets the condition α=N1·αα. A second device controls the rotation of the ring portion defining an angular step ββ such that an integer N2 other than 1 meets the condition β=N2·ββ.

Abstract translation: 扫描照明装置包括在照明扇区中从其发射辐射的发射中心。 圆柱形环在源体上居中并且可围绕第一轴线可旋转地移动。 环包括围绕其旋转轴规则分布并且具有相同角度振幅α的多个狭缝。 圆筒部分以源为中心，并且可围绕中心与第一轴线交叉的第二轴线可旋转地移动，并与其形成非零的角度。 圆筒部包括具有角度振幅β的狭缝。 环的旋转的第一设备控制，限定基本角度步长，使得除了1以外的整数N1满足条件α= N1·αα。 第二装置控制限定角度步长ββ的环部分的旋转，使得除了1以外的整数N2满足条件β= N2·ββ。

公开(公告)号：US20160178520A1

公开(公告)日：2016-06-23

申请号：US14973306

申请日：2015-12-17

Applicant: Singulex, Inc.

Inventor： Richard Livingston ,  Michele Gilbert ,  Jacqueline Felberg ,  Jeffrey Bishop

IPC: G01N21/64 ,  G01N33/536 ,  G01N33/68 ,  G01N33/53

CPC classification number: G01N21/6428 ,  G01J3/4406 ,  G01N21/645 ,  G01N21/6452 ,  G01N33/5302 ,  G01N33/536 ,  G01N33/58 ,  G01N33/6845 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2201/0612 ,  G01N2201/103 ,  G01N2201/104 ,  G01N2201/105

Abstract: Analyzers and analyzer systems that include an analyzer for determining multiple label species, methods of using the analyzer and analyzer systems to analyze samples, are disclosed herein. The analyzer includes one or more sources of electromagnetic radiation to provide electromagnetic radiation at wavelengths within the excitation bands of one or more fluorophore species to an interrogation space that is translated through the sample to detect the presence or absence of molecules of different target analytes. The analyzer may also include one or more detectors configured to detect electromagnetic radiation emitted from the one or more fluorophore species. The analyzer for determining multiple target molecule species provided herein is useful for diagnostics because the concentration of multiple species of target molecules may be determined in a single sample and with a single system.

Abstract translation: 本文公开了包括用于确定多个标签种类的分析器，使用分析仪和分析仪系统分析样品的方法的分析仪和分析仪系统。 分析仪包括一个或多个电磁辐射源，以将一个或多个荧光团物质的激发带内的波长处的电磁辐射提供给通过样品翻译的询问空间，以检测不同目标分析物的分子的存在或不存在。 分析器还可以包括被配置为检测从一个或多个荧光团物种发射的电磁辐射的一个或多个检测器。 用于确定本文提供的多种靶分子物质的分析仪可用于诊断，因为可以在单个样品中和单个系统中确定多种目标分子的浓度。