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62 条记录 (耗时 0.015 秒)

    ACOUSTIC FOCUSING CHIP
    41.
    发明公开
    ACOUSTIC FOCUSING CHIP 审中-公开

    公开(公告)号：US20240175797A1

    公开(公告)日：2024-05-30

    申请号：US18434013

    申请日：2024-02-06

    申请人： ThinkCyte K. K.

    发明人： Toru Imai ,  Mohammad Ryota Suyama

    IPC分类号： G01N15/1404

    CPC分类号： G01N15/1404 ,  G01N2015/142

    摘要： An acoustic focusing chip is irradiated with ultrasonic waves from an acoustic element P. A flow path having an inlet and an outlet is formed inside of a plate body along a plate surface. A region proximate to the inlet of the flow path of the plate body is set as an ultrasonic wave application region for receiving irradiation of the ultrasonic waves. The acoustic element is arranged on the plate surface in the ultrasonic wave application region. A reflective portion capable of reflecting the ultrasonic waves toward the flow path is formed along the flow path in the ultrasonic wave application region. Thereby, the flow focusing ability, heat dissipation, and strength retention can be cost-effectively improved with a simple configuration.

    METHODS AND SYSTEMS FOR FAST RECOMPENSATION OF FLOW CYTOMETERY DATA
    44.
    发明公开
    METHODS AND SYSTEMS FOR FAST RECOMPENSATION OF FLOW CYTOMETERY DATA 审中-公开

    公开(公告)号：US20240142366A1

    公开(公告)日：2024-05-02

    申请号：US18478925

    申请日：2023-09-29

    申请人： CYTEK BIOSCIENCES, INC.

    发明人： Zhenyu Zhang

    IPC分类号： G01N15/1404 ,  G01N15/14

    CPC分类号： G01N15/1404 ,  G01N15/1425 ,  G01N15/1484 ,  G01N15/1434

    摘要： In one embodiment, a method of performing fast compensation in a flow cytometry experiment is provided. The method includes the following: generating an initial spillover matrix by using a plurality of single stained compensation controls; running a sample through the flow cytometer; generating a measured sample event vector by measuring fluorescence of a plurality of cells passing through the flow cytometer; generating a compensated sample event vector by using the initial spillover matrix and the measured sample event vector; generating an adjusted spillover matrix by finely adjusting the initial spill-over matrix; and calculating a re-compensated event vector by using the adjusted spillover matrix and the measured sample event vector.

    Flow cytometry apparatus and methods
    45.
    发明授权
    Flow cytometry apparatus and methods 有权

    公开(公告)号：US11965815B2

    公开(公告)日：2024-04-23

    申请号：US18165234

    申请日：2023-02-06

    申请人： Kinetic River Corp.

    发明人： Giacomo Vacca

    IPC分类号： G01N15/14 ,  G01N15/1404 ,  G01N15/1434 ,  G01N15/10

    CPC分类号： G01N15/1436 ,  G01N15/1404 ,  G01N15/1459 ,  G01N2015/1006 ,  G01N2015/1415 ,  G01N2015/149

    摘要： A particle analyzer, comprising a source of a substantially nondiffracting light beam; a flow path configured to produce in a flowcell a ribbon-like core stream having a specific cross-sectional aspect ratio; the flowcell being configured to expose a segment of the core stream to the light beam; a detector configured to receive a signal resulting from an interaction of a particle in the core stream with the light beam; a first sorting actuator connected with the flowcell, downstream of the exposed segment of core stream; a plurality of sorting channels in fluid connection with the flow path and downstream of the first actuator; the actuator having multiple actuation states, each state configured to direct at least one part of the core stream to a corresponding channel; a second sorting actuator connected with the flowcell, opposite the first actuator, and operable in coordination with the first actuator.

    Hydrodynamic focusing device
    47.
    发明授权
    Hydrodynamic focusing device 有权

    公开(公告)号：US12111243B2

    公开(公告)日：2024-10-08

    申请号：US17779344

    申请日：2020-12-01

    申请人： Foss Analytical A/S

    发明人： Christer Zoffmann Bisgaard ,  Anders Brask ,  Miguel Carro Temboury

    IPC分类号： G01N15/1404 ,  G01N15/1434

    CPC分类号： G01N15/1404 ,  G01N15/1436 ,  G01N2015/1413

    摘要： A hydrodynamic focusing device comprises first and second flow channels; a wall at least partially defining an envelopment region connected in-line between the first and second flow channels which collectively define a flow direction extending therethrough; and a chimney comprising a body and a sample fluid inlet, extending from the wall and into the envelopment region. The sample fluid inlet faces at least partially perpendicular to the flow direction in the envelopment region, such that the sample fluid inlet is configured to supply a sample fluid into the envelopment region in a direction that is at least partially perpendicular to the flow direction. The body and the sample fluid inlet each have an elongate profile which has a rounded leading edge facing the first flow channel and opposing long edges connecting the leading and trailing edges and tapered towards the trailing edge.

    Phase-correction of radiofrequency-multiplexed signals
    48.
    发明授权
    Phase-correction of radiofrequency-multiplexed signals 有权

    公开(公告)号：US12105010B2

    公开(公告)日：2024-10-01

    申请号：US18373487

    申请日：2023-09-27

    申请人： Becton, Dickinson and Company

    发明人： Jonathan Lin ,  Keegan Owsley ,  Matthew Bahr

    IPC分类号： G01N15/14 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/149 ,  G01N15/1404

    CPC分类号： G01N15/1459 ,  G01N15/1425 ,  G01N15/1429 ,  G01N15/1434 ,  G01N2015/1402 ,  G01N2015/142 ,  G01N2015/1486 ,  G01N15/149

    摘要： Aspects of the present disclosure include methods for characterizing particles of a sample in a flow stream. Methods according to certain embodiments include generating frequency-encoded fluorescence data from a particle of a sample in a flow stream; and calculating phase-corrected spatial data of the particle by performing a transform of the frequency-encoded fluorescence data with a phase correction component. In certain embodiments, methods include generating an image of the particle in the flow stream based on the phase-corrected spatial data. Systems having a processor with memory operably coupled to the processor having instructions stored thereon, which when executed by the processor, cause the processor to calculate phase-corrected spatial data from frequency-encoded fluorescence data of a particle a flow stream are also described. Integrated circuit devices (e.g., field programmable gate arrays) having programming for practicing the subject methods are also provided.