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80 条记录 (耗时 0.031 秒)

    Glucose monitoring system
    61.
    发明授权
    Glucose monitoring system 失效
    葡萄糖监测系统

    公开(公告)号：US5497772A

    公开(公告)日：1996-03-12

    申请号：US155737

    申请日：1993-11-19

    申请人： Joseph H. Schulman ,  Orville R. Rule, III ,  David I. Whitmoyer ,  Ronald J. Lebel ,  Joseph Y. Lucisano ,  Alfred E. Mann

    发明人： Joseph H. Schulman ,  Orville R. Rule, III ,  David I. Whitmoyer ,  Ronald J. Lebel ,  Joseph Y. Lucisano ,  Alfred E. Mann

    IPC分类号： A61B5/00 ,  A61B5/05

    CPC分类号： A61B5/14865 ,  A61B5/1495 ,  A61B5/6849 ,  A61B2562/08 ,  A61B5/742

    摘要： A glucose monitoring system continuously measures the glucose concentration in a patient's blood, provides an indication of the rate of change of such concentration, and determines whether the measured concentration and rate of change are within certain preset limits. If not, an audible and/or visual alarm signal is generated. The glucose monitoring system includes a glucose sensor adapted to be inserted into the venous system of the patient, where it responds to blood glucose and produces sensor signals related to the glucose concentration. The sensor signals are delivered through a suitable interconnect cable to a glucose monitor. In one embodiment, the interconnect cable includes a contactless connector that electrically isolates the glucose sensor from the monitor, and reduces the number of conductors required to interface with a plurality of sensors. The glucose monitor interprets the sensor signals by applying a previously determined calibration to quantitatively determine the blood glucose value. The blood glucose value thus determined is then processed in order to determine the rate of change, is stored (to create a history or record), and may also be displayed in large, easy-to-read numerals. Rate of change information (trend) may also be numerically or graphically displayed.

    摘要翻译： 葡萄糖监测系统连续测量患者血液中的葡萄糖浓度，提供这种浓度变化率的指示，并确定测量的浓度和变化率是否在某些预设限度内。 如果没有，则产生声音和/或视觉报警信号。 葡萄糖监测系统包括适于插入患者静脉系统中的葡萄糖传感器，其响应于血糖并产生与葡萄糖浓度相关的传感器信号。 传感器信号通过合适的互连电缆传送到葡萄糖监测器。 在一个实施例中，互连电缆包括非接触式连接器，其将葡萄糖传感器与监视器电隔离，并且减少与多个传感器接合所需的导体的数量。 葡萄糖监测器通过应用预先确定的校准来定量地确定血糖值来解释传感器信号。 然后处理如此确定的血糖值以确定变化率，存储（创建历史或记录），并且还可以以大的易于阅读的数字显示。 变化率信息（趋势）也可以数字或图形显示。

    Replaceable catheter system for physiological sensors, tissue stimulating electrodes and/or implantable fluid delivery systems
    62.
    发明授权
    Replaceable catheter system for physiological sensors, tissue stimulating electrodes and/or implantable fluid delivery systems 失效
    用于生理传感器，组织刺激电极和/或可植入流体递送系统的可更换的导管系统

    公开(公告)号：US5484404A

    公开(公告)日：1996-01-16

    申请号：US239357

    申请日：1994-05-06

    申请人： Joseph H. Schulman ,  Alfred E. Mann

    发明人： Joseph H. Schulman ,  Alfred E. Mann

    IPC分类号： A61N1/05 ,  A61N1/04

    CPC分类号： A61B5/6865 ,  A61N1/05

    摘要： A replaceable catheter system provides a way to replace an implantable sensor, electrode system, and/or fluid delivery/receiving system. The replaceable catheter includes an elongated tubular catheter holder for surgical implantation in a patient. The catheter holder has an open neck at a proximal end thereof just under the patient's skin. A distal end of the catheter holder extends into a body cavity in the patient. A manually replaceable catheter is inserted through a self-sealing barrier over the open end of the catheter holder. A distal end of the replaceable catheter extends longitudinally through the catheter holder and beyond the distal end thereof to expose one or more physiological/chemical sensors, tissues stimulating electrodes, and/or a fluid delivery/receiving tube carried by or formed within the replaceable catheter. The sensors and/or electrodes are electrically connected to an electronic package including a signal coupler adjacent a signal coupler carried by the catheter holder. The signal coupler is connected to an implanted control device whereby electrical signals are transmitted to and/or from the sensor and/or electrode from the control device. The control device may include, or be connected to, an implantable fluid dispenser/analyzer for dispensing or analyzing fluid via a conduit connected through the catheter holder to an opening in the replaceable catheter.

    摘要翻译： 可替换的导管系统提供了替代可植入传感器，电极系统和/或流体递送/接收系统的方法。 可更换的导管包括用于患者手术植入的细长管状导管保持器。 导管保持器在其刚好在患者皮肤下方的近端处具有开口的颈部。 导管保持器的远端延伸到患者体内的体腔中。 可手动更换的导管穿过导管保持器的开口端上的自密封屏障插入。 可替换导管的远端纵向延伸穿过导管保持器并且超过其远端以暴露一个或多个生理/化学传感器，刺激电极的组织和/或由可更换导管承载或形成的流体输送/接收管 。 传感器和/或电极电连接到电子封装，该电子封装包括邻近由导管保持器承载的信号耦合器的信号耦合器。 信号耦合器连接到植入的控制装置，由此电信号从控制装置传送到传感器和/或电极。 控制装置可以包括或连接到可植入流体分配器/分析器，用于经由通过导管保持器连接的导管分配或分析流体到可更换导管中的开口。

    Implantable stimulator
    66.
    发明授权
    Implantable stimulator 失效
    植入式刺激器

    公开(公告)号：US08630705B2

    公开(公告)日：2014-01-14

    申请号：US13053031

    申请日：2011-03-21

    申请人： Alfred E. Mann ,  Tom Xiaohai He

    发明人： Alfred E. Mann ,  Tom Xiaohai He

    IPC分类号： A61N1/00

    CPC分类号： A61N1/375 ,  A61N1/3605 ,  A61N1/37205 ,  A61N1/3756

    摘要： An implantable stimulator includes a tube assembly that is configured to house a number of components that are configured to apply at least one stimulus to at least one stimulation site within a patient. The tube assembly has a shape that allows the stimulator to be implanted within said patient in a pre-determined orientation. Exemplary methods of stimulating a stimulation site within a patient include applying an electrical stimulation current to a stimulation site via one or more electrodes extending along one or more sides of a stimulator. The stimulator has a shape allowing the stimulator to be implanted within the patient in a pre-determined orientation.

    摘要翻译： 可植入刺激器包括管组件，其被配置为容纳多个部件，所述部件被配置为将至少一个刺激应用于患者内的至少一个刺激部位。 管组件具有允许刺激器以预定方向植入所述患者体内的形状。 刺激患者内的刺激部位的示例性方法包括通过沿刺激器的一侧或多侧延伸的一个或多个电极将电刺激电流施加到刺激部位。 刺激器具有允许刺激器以预定方向植入患者体内的形状。

    Percutaneous cochlear implant systems and methods
    67.
    发明授权
    Percutaneous cochlear implant systems and methods 失效
    经皮耳蜗植入系统和方法

    公开(公告)号：US08554329B1

    公开(公告)日：2013-10-08

    申请号：US12816142

    申请日：2010-06-15

    申请人： Alfred E. Mann ,  Matthew I. Haller ,  Tom Xiaohai He

    发明人： Alfred E. Mann ,  Matthew I. Haller ,  Tom Xiaohai He

    IPC分类号： H04R25/00

    CPC分类号： A61N1/0541 ,  A61N1/0526 ,  A61N1/3605 ,  H04R25/606

    摘要： A percutaneous cochlear implant system includes a cochlear stimulator configured to be coupled to an electrode lead, the electrode lead comprising a plurality of electrodes configured to be in communication with a plurality of stimulation sites within a cochlear region of a patient, a sound processor communicatively coupled to the cochlear stimulator and configured to control the cochlear stimulator to generate and apply electrical stimuli representative of an audio signal to at least one of the stimulation sites via at least one of the electrodes, a power source configured to provide power to at least one of the cochlear stimulator and the sound processor, and a percutaneous port configured to be percutaneously implanted within a head of the patient. The percutaneous port may be configured to house at least one of the power source, sound processor, and cochlear stimulator. Additionally or alternatively, the percutaneous port is configured to facilitate programming, recharging of a rechargeable power source (e.g., implanted battery), control of, and/or access to at least one of the power source, sound processor, and cochlear stimulator.

    摘要翻译： 经皮耳蜗植入系统包括被配置为耦合到电极引线的耳蜗刺激器，所述电极引线包括被配置为与患者的耳蜗区域内的多个刺激部位连通的多个电极，声音处理器通信耦合 并且被配置为控制所述耳蜗刺激器以经由至少一个所述电极产生并将表示音频信号的电刺激施加到所述刺激部位中的至少一个，电源，被配置为向至少一个 耳蜗刺激器和声音处理器以及被配置为经皮植入患者头部的经皮端口。 经皮端口可以被配置为容纳电源，声音处理器和耳蜗刺激器中的至少一个。 附加地或替代地，经皮端口被配置为便于对可再充电电源（例如，植入的电池）进行编程，对电源，声音处理器和耳蜗刺激器中的至少一个的控制和/或访问的再充电。

    Fully implantable hearing aid system
    70.
    发明授权
    Fully implantable hearing aid system 失效
    完全植入式助听器系统

    公开(公告)号：US08142344B2

    公开(公告)日：2012-03-27

    申请号：US11883728

    申请日：2006-02-23

    申请人： William H. Slattery, III ,  Alfred E. Mann ,  Byron L. Moran

    发明人： William H. Slattery, III ,  Alfred E. Mann ,  Byron L. Moran

    IPC分类号： H04R25/00

    CPC分类号： H04R25/604 ,  H04R25/554 ,  H04R25/558 ,  H04R2225/67

    摘要： A fully implantable hearing aid system comprised of an implantable sound generator module and an implantable sound receiver module connected by an implantable electric cable. The system includes: a) a sound generator module configured for implantation in subcutaneous tissue to place an output electric/acoustic (E/A) transducer, e.g., a speaker, immediately adjacent to, or preferably, extending percutaneously into, a patient's outer ear canal; b) a sound receiver module configured for implantation proximate to a patient's pinna to place an input acoustic/electric (AJE) transducer, e.g., a microphone, so that it is acoustically isolated from the E/A transducer; and c) an electric cable configured for implantation in subcutaneous tissue for directly electrically connecting said sound receiver module and said sound generator module.

    摘要翻译： 一种完全可植入的助听器系统，包括由可植入电缆连接的可植入声音发生器模块和可植入声音接收器模块。 该系统包括：a）声音发生器模块，其配置用于植入皮下组织以将输出的电/声（E / A）换能器，例如扬声器紧邻或优选地经皮延伸到患者的外耳 运河; b）声音接收器模块，其配置用于在患者的耳廓附近植入以放置例如麦克风的输入声/电（AJE）换能器，使得其与E / A换能器声学隔离; 以及c）配置用于植入皮下组织以直接电连接所述声音接收器模块和所述声音发生器模块的电缆。