公开(公告)号：US11925453B2

公开(公告)日：2024-03-12

申请号：US17222389

申请日：2021-04-05

申请人： KONINKLIJKE PHILIPS N.V.

发明人： Aditya Mehendale ,  Funda Sahin ,  Gregory Cole ,  Hao Su ,  Vijay Parthasarathy

IPC分类号： A61B5/06 ,  A61B1/267 ,  A61B5/00 ,  A61B17/00 ,  A61B34/20 ,  A61M25/01 ,  A61M25/09 ,  A61B34/30

CPC分类号： A61B5/062 ,  A61B1/2676 ,  A61B5/425 ,  A61B17/00234 ,  A61B34/20 ,  A61M25/0127 ,  A61M25/09 ,  A61B2017/00274 ,  A61B2034/2051 ,  A61B2034/2061 ,  A61B2034/301

摘要： A medical device for the electromagnetic tracking of a medical instrument transported through the medical device. The medical device has a central axis and a channel that receives and transports a medical instrument through the medical device. The channel extends to a distal portion of the medical device and connects with an opening in the medical device that is not aligned with the central axis. The medical device includes a tracking component that is a plurality of coordinated electromagnetic sensors for generating a virtual axis of travel for the medical instrument, with the virtual axis passing through the opening of the device and being aligned with tool insertion axis.

公开(公告)号：US20240008801A1

公开(公告)日：2024-01-11

申请号：US18023927

申请日：2021-09-01

申请人： The Research Foundation for the SUNY

发明人： Arie Kaufman ,  Konstantin Dmietriev ,  Shreeraj Jadhav

IPC分类号： A61B5/00 ,  G16H10/60 ,  G06T7/00 ,  G06T7/11

CPC分类号： A61B5/425 ,  A61B5/7267 ,  A61B5/743 ,  G16H10/60 ,  G06T7/0012 ,  G06T7/11 ,  G06T2207/10081 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30096 ,  G06T2207/30092

摘要： Systems and methods for virtual pancreatography (VP) are disclosed for non-invasive diagnosis and classification of pancreatic lesions. VP is an end-to-end visual diagnosis system that includes: automatic segmentation of the pancreatic gland and the lesions, extraction of the primary pancreatic duct, automatic classification of lesions into a plurality of lesion types, and specialized 3D and 2D exploratory visualizations of the pancreas, lesions and surrounding anatomy. Volume rendering is combined with pancreas and lesion centric visualizations and measurements for effective diagnosis.

公开(公告)号：US11713305B2

公开(公告)日：2023-08-01

申请号：US16026340

申请日：2018-07-03

申请人： The Board of Regents of the University of Texas System

发明人： Andre F. Martins ,  Sara Chirayil ,  Maria Veronica Clavijo Jordan ,  A. Dean Sherry

IPC分类号： C07D401/14 ,  A61K49/10 ,  A61B5/00 ,  C07F5/00 ,  G01R33/56 ,  A61B5/055

CPC分类号： C07D401/14 ,  A61B5/004 ,  A61B5/055 ,  A61B5/425 ,  A61B5/4381 ,  A61K49/106 ,  C07F5/003 ,  G01R33/5601

摘要： In some aspects, the present disclosure provides gadolinium based sensors which may be used to image zinc ions in vivo. In some embodiments, the compounds show appropriate reactivity with zinc ions while maintaining high relaxivity to achieve improved background relative to other sensors.

公开(公告)号：US20190246938A1

公开(公告)日：2019-08-15

申请号：US15747202

申请日：2016-06-09

申请人： Northeastern University

发明人： Codi GHARAGOUZLOO ,  Srinivas SRIDHAR

IPC分类号： A61B5/055 ,  A61B5/00 ,  G01R33/48 ,  G01R33/56 ,  G01R33/563

CPC分类号： A61B5/055 ,  A61B5/4064 ,  A61B5/4088 ,  A61B5/4244 ,  A61B5/425 ,  A61B5/4866 ,  A61B2576/026 ,  G01R33/4816 ,  G01R33/5601 ,  G01R33/5635 ,  G01R33/56366

摘要： A quantitative, ultrashort time to echo, contrast-enhanced magnetic resonance imaging technique is provided. The technique can be used to accurately measure contrast agent concentration in the blood, to provide clear, high-definition angiograms, and to measure absolute quantities of cerebral blood volume on a voxel-by-voxel basis.

公开(公告)号：US20180177429A1

公开(公告)日：2018-06-28

申请号：US15389604

申请日：2016-12-23

申请人： Edward R Flynn

发明人： Edward R Flynn

IPC分类号： A61B5/05 ,  G01N33/574 ,  G01N33/553 ,  A61B5/00 ,  A61K49/18

CPC分类号： A61B5/0515 ,  A61B5/004 ,  A61B5/425 ,  A61B5/4312 ,  A61B5/4325 ,  A61B5/4381 ,  A61B5/7425 ,  A61B2503/40 ,  A61B2503/42 ,  A61B2562/0223 ,  A61B2562/04 ,  A61B2576/02 ,  A61K49/1875 ,  G01N33/54326 ,  G01N33/54346 ,  G01N33/569

摘要： The present invention can provide a method of determining the presence, location, quantity, or a combination thereof, of a biological substance, comprising: (a) exposing a sample to a plurality of targeted nanoparticles, where each targeted nanoparticle comprises a paramagnetic nanoparticle conjugated with one or more targeting agents that preferentially bind with the biological substance, under conditions that facilitate binding of the targeting agent to at least one of the one or more biological substances; (b) subjecting the sample to a magnetic field of sufficient strength to induce magnetization of the nanoparticles; (c) measuring a magnetic field of the sample after decreasing the magnetic field applied in step b below a threshold; (d) determining the presence, location, quantity, or a combination thereof, of the one or more biologic substances from the magnetic field measured in step (c).

公开(公告)号：US20180000404A1

公开(公告)日：2018-01-04

申请号：US15635854

申请日：2017-06-28

申请人： Mark W. Jones

发明人： Mark W. Jones

IPC分类号： A61B5/00 ,  A61B5/145 ,  A61F13/36 ,  A61B5/1473 ,  A61K49/00

CPC分类号： A61B5/425 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/4283 ,  A61B2505/05 ,  A61B2562/0295 ,  A61F13/36 ,  A61K49/006 ,  A61K49/0069 ,  C12Q1/40 ,  G01N33/528

摘要： A method and system are provided for detecting pancreatic trauma in a trauma patient during a surgical operation. The method includes positioning a detection device in contact with the patient's pancreas, applying a chemical indicator to the detection device after removing the detection device from the patient, and detecting a chemical reaction on the detection device that is indicative of the pancreas releasing an enzyme as a result of pancreatic trauma.

公开(公告)号：US20170086802A1

公开(公告)日：2017-03-30

申请号：US15374249

申请日：2016-12-09

申请人： OLYMPUS CORPORATION

发明人： Tomohiko MAMIYA ,  Nozomu KOTAKE

IPC分类号： A61B10/04 ,  A61B1/005 ,  A61B5/00 ,  A61B8/12 ,  A61B1/273 ,  A61B1/018 ,  A61B1/00

CPC分类号： A61B10/04 ,  A61B1/00098 ,  A61B1/00137 ,  A61B1/005 ,  A61B1/018 ,  A61B1/2736 ,  A61B5/425 ,  A61B8/12 ,  A61B2010/045 ,  A61M25/0097 ,  A61M25/1025 ,  A61M39/10

摘要： A biopsy system includes an endoscope which includes an insertion portion having a channel, and a bendable portion provided in a distal end portion of the insertion portion; a needle tube which includes a distal end region, and a proximal end region having a higher bending rigidity than that of the distal end region; a sheath which can be inserted into the channel and inserted through by the needle tube; an attachment adapter which is provided on a proximal end side of the sheath and is capable of being mounted at the endoscope; and a connection member which connects the distal end region and the proximal end region, wherein the connection member can move within only a range of the insertion portion more proximal than a proximal end of the bendable portion and more distal than a proximal end of a follow-bending region.

公开(公告)号：US20170042445A1

公开(公告)日：2017-02-16

申请号：US15118689

申请日：2015-02-12

申请人： The Methodist Hospital

发明人： Albert Yung-Hsiang Huang

IPC分类号： A61B5/0488 ,  A61B5/00 ,  A61N1/05 ,  A61B5/0492 ,  A61N1/378 ,  A61B1/307 ,  A61B17/34 ,  A61B5/11 ,  A61B5/20 ,  A61N1/36

CPC分类号： A61B5/04882 ,  A61B1/307 ,  A61B5/0492 ,  A61B5/1107 ,  A61B5/20 ,  A61B5/425 ,  A61B5/4283 ,  A61B5/4887 ,  A61B5/7415 ,  A61B17/3423 ,  A61B2090/065 ,  A61N1/0521 ,  A61N1/36007 ,  A61N1/378

摘要： A method for identifying a ureter during a medical procedure, the method comprising: providing an electrical stimulator comprising: a shaft having at least one electrode; and a power supply connected to the at least one electrode for providing an electrical signal to the at least one electrode; advancing the shaft so that the at least one electrode contacts tissue; operating the power supply so that the electrical signal is applied to the tissue; and visually observing the tissue to determine the presence of a ureter in the tissue.

摘要翻译： 一种用于在医疗过程中识别输尿管的方法，所述方法包括：提供电刺激器，其包括：具有至少一个电极的轴; 以及连接到所述至少一个电极的电源，用于向所述至少一个电极提供电信号; 推进所述轴，使得所述至少一个电极接触组织; 操作电源，使得电信号施加到组织; 并且目视观察组织以确定组织中输尿管的存在。

公开(公告)号：US09421370B2

公开(公告)日：2016-08-23

申请号：US14223701

申请日：2014-03-24

申请人： Ronald J Weinstock

发明人： Ronald J Weinstock

IPC分类号： A61N1/36 ,  A61B5/053 ,  A61N2/00 ,  A61N2/02 ,  A61B5/04 ,  A61B5/08 ,  A61B5/00

CPC分类号： A61N1/3606 ,  A61B5/04001 ,  A61B5/053 ,  A61B5/0531 ,  A61B5/08 ,  A61B5/4227 ,  A61B5/4244 ,  A61B5/425 ,  A61B5/448 ,  A61B5/6823 ,  A61N2/006 ,  A61N2/008 ,  A61N2/02

摘要： An electrotherapeutic treatment system includes a portion of at least one skin or external contact element including an element for measurement of the bioreactance of biologically active neurological points (BANP) of a tissue or organ to be treated, monitoring of electromagnetic parameters received at the points and generating responsive corrective parameters; and a portion of a second electrode for neurologically transmitting bioreactive parameters proximally to a BANP of tissues or organs to be treated, the parameters modifying discrete reactive values responsive to those measured by each of the first or second electrodes responsive to abnormal parameters received from tissues or organs to be treated at or between the BANP.

摘要翻译： 电疗治疗系统包括至少一个皮肤或外部接触元件的一部分，其包括用于测量要处理的组织或器官的生物活性神经学点（BANP）的生物反应的元件，监测在该点接收的电磁参数，以及 产生响应校正参数; 以及用于将生物反应性参数神经传递给待治疗的组织或器官的BANP的第二电极的一部分，所述参数根据从组织接收的异常参数响应于由第一或第二电极中的每一个测量的离散反应值， 在BANP之间或之间进行治疗的器官。

公开(公告)号：US09320451B2

公开(公告)日：2016-04-26

申请号：US14191967

申请日：2014-02-27

申请人： Kimberly-Clark Worldwide, Inc.

发明人： Joseph R. Feldkamp ,  Shawn Jeffery Sullivan

IPC分类号： A61B5/05 ,  A61B5/00

CPC分类号： A61B5/0522 ,  A61B5/0042 ,  A61B5/0536 ,  A61B5/08 ,  A61B5/4238 ,  A61B5/425 ,  A61B5/4255 ,  A61B5/4312 ,  A61B5/445 ,  A61B5/4566 ,  A61B5/702 ,  A61B5/708 ,  A61B5/7425 ,  G01R33/34

摘要： Methods for assessing a health condition of an individual using single coil magnetic induction tomography imaging are provided. A target area for medical imaging on a patient can be identified. A plurality of coil property measurements can be obtained using a single coil. The plurality of coil property measurements can be performed with the single coil at a plurality of discrete locations relative to the target area. The coil property measurements can be processed to generate an image of the conductivity distribution of the target area. The image can be analyzed to assess a health condition of the patient.

摘要翻译： 提供了使用单线圈磁感应层析成像来评估个体健康状况的方法。 可以鉴定患者的医学成像的目标区域。 可以使用单个线圈获得多个线圈特性测量。 可以在相对于目标区域的多个离散位置处的单个线圈执行多个线圈特性测量。 可以处理线圈特性测量以产生目标区域的电导率分布的图像。 可以分析图像以评估患者的健康状况。