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179 条记录 (耗时 0.04 秒)

    SELF-REGULATING PRESSURE SOURCE
    81.
    发明申请
    SELF-REGULATING PRESSURE SOURCE 有权
    自调压源

    公开(公告)号：US20120272642A1

    公开(公告)日：2012-11-01

    申请号：US13420886

    申请日：2012-03-15

    申请人： Cagdas Denizel Onal ,  Daniela Rus ,  Xin Chen ,  George M. Whitesides

    发明人： Cagdas Denizel Onal ,  Daniela Rus ,  Xin Chen ,  George M. Whitesides

    IPC分类号： F15B13/16 ,  B01J19/00

    CPC分类号： G05D16/0636 ,  F15B21/06

    摘要： Self-regulating pressure source. The pressure source includes a chamber enclosing a chemical monopropellant. A moveable boss is attached to a deformable membrane sealing an air chamber, the moveable boss and air chamber being disposed within the chamber. A catalyst is disposed around the membrane so as to be covered by the boss in a retracted position so that the monopropellant is broken down by the catalyst to produce a gas. The gas pressure will increase within the chamber causing air in the air chamber to compress thereby to pull the boss into the retracted position to cover the catalyst thereby to regulate the pressure within the chamber. The self-regulating pressure source is particularly suited to power fluidic elastomeric actuators.

    摘要翻译： 自调压源。 压力源包括封闭化学单元推进剂的室。 可移动的凸台连接到密封空气室的可变形膜，可移动的凸台和空气室设置在室内。 催化剂设置在膜周围，以便被凸起覆盖在缩回位置，使得单组分推进剂被催化剂分解以产生气体。 在室内气体压力将增加，导致空气室中的空气压缩，从而将凸台拉到缩回位置以覆盖催化剂，从而调节室内的压力。 自调节压力源特别适用于流体弹性致动器。

    Methods of alteration of surface affinities using non-chemical force-creating fields
    85.
    发明授权
    Methods of alteration of surface affinities using non-chemical force-creating fields 有权
    使用非化学力创造领域改变表面亲和力的方法

    公开(公告)号：US07659053B2

    公开(公告)日：2010-02-09

    申请号：US11181371

    申请日：2005-07-14

    申请人： Xingyu Jiang ,  Rosaria Ferrigno ,  George M. Whitesides

    发明人： Xingyu Jiang ,  Rosaria Ferrigno ,  George M. Whitesides

    IPC分类号： C12Q1/00 ,  G01N33/53

    CPC分类号： B82Y30/00 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3225 ,  B01J20/3227 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/3274 ,  B01J20/3285 ,  B01J2219/00497 ,  B01J2219/00527 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00743 ,  B05D3/14 ,  B05D3/207 ,  G01N33/54353 ,  G01N2610/00 ,  Y10S436/823 ,  Y10T436/118339

    摘要： The present invention provides a series of methods, compositions, and articles for altering a property of a surface (for example, the cytophilicity and/or the hydrophilicity), by exposing at least a portion of the surface to a non-chemical, force-creating field and/or force, such as an electric field. The field/force may be created by any suitable technique. For instance, the field can be created by applying a voltage across the surface, by electrical induction, etc. In certain embodiments, the surface includes molecules attached thereto that can be detached when exposed to non-chemical, force-creating fields and/or forces, thereby altering the chemical composition of at least a portion of the surface. In one set of embodiments, the molecules attached to the surface may include molecules forming a self-assembled monolayer on the surface. In some embodiments, the molecules attached to the surface may include thiol moieties (e.g., as in an alkanethiol), by which the molecule can become attached to the surface. In certain cases, the molecules may be terminated at the unattached end with one or more hydrophilic groups, for example, unmodified ethylene glycol moieties. In some cases, the molecules attached to the surface may include one or more moieties that can bind to various entities such as proteins, peptides, nucleic acids, drugs, cells, etc. In certain embodiments, the techniques are used to enable novel assays for cell motility and/or spreading and screening tests for determining drugs and/or treatments effective in increasing or decreasing cell shape changes and/or motility on surfaces.

    摘要翻译： 本发明提供了一系列用于改变表面性质（例如，细胞毒性和/或亲水性）的方法，组合物和制品，通过将至少一部分表面暴露于非化学， 产生场和/或力，例如电场。 场/力可以通过任何合适的技术来产生。 例如，可以通过在表面上施加电压，通过电感应等来产生该场。在某些实施例中，表面包括附着于其上的分子，当暴露于非化学，力产生场和/或 从而改变表面的至少一部分的化学成分。 在一组实施方案中，连接到表面的分子可以包括在表面上形成自组装单层的分子。 在一些实施方案中，附着于表面的分子可以包括硫醇部分（例如，如在链烷硫醇中），通过该分子可以使分子附着于表面。 在某些情况下，分子可以在一个或多个亲水基团例如未改性的乙二醇部分的非附着端封端。 在一些情况下，附着于表面的分子可以包括可结合各种实体的一个或多个部分，例如蛋白质，肽，核酸，药物，细胞等。在某些实施方案中，该技术用于使新的测定方法 用于确定有效增加或减少细胞形状变化和/或表面活力的药物和/或治疗的细胞运动性和/或扩散和筛选试验。

    Fluid waveguide and uses thereof
    86.
    发明申请
    Fluid waveguide and uses thereof 审中-公开
    流体波导及其用途

    公开(公告)号：US20090097808A1

    公开(公告)日：2009-04-16

    申请号：US11658339

    申请日：2005-08-01

    申请人： Daniel B. Wolfe ,  Kateri E. Paul ,  Dmitri V. Vezenov ,  Brian T. Mayers ,  Richard S. Conroy ,  Piotr Garstecki ,  Michael A. Fischbach ,  Valentine I. Vullev ,  Kam Yan Tang ,  Mara G. Prentiss ,  George M. Whitesides

    发明人： Daniel B. Wolfe ,  Kateri E. Paul ,  Dmitri V. Vezenov ,  Brian T. Mayers ,  Richard S. Conroy ,  Piotr Garstecki ,  Michael A. Fischbach ,  Valentine I. Vullev ,  Kam Yan Tang ,  Mara G. Prentiss ,  George M. Whitesides

    IPC分类号： G02B6/032

    CPC分类号： G02B6/032 ,  G02B6/10 ,  G02B6/122

    摘要： The invention relates to methods and apparatuses for guiding and emitting electromagnetic radiation from a fluid waveguide. Various methods for changing optical properties (e.g., refractive index, absorption, and fluorescence) and/or physical properties (e.g., magnetic susceptibility, electrical conductivity, and temperature) of either the waveguide core or the cladding, or both, are provided herein. In one embodiment, electromagnetic radiation is guided and/or emitted at multiple distinct wavelengths, including emission in the form of an essentially continuous band, in some cases covering at least 150 nanometers. In another embodiment, methods for splitting a waveguide core and/or the joining of at least two waveguide cores in a waveguide are provided. In yet another embodiment, the invention includes the use of thermal gradients to generate a waveguide and/or to change the properties of waveguides. Embodiments of the waveguides may be used for optical detection or spectroscopic analysis.

    摘要翻译： 本发明涉及用于引导和发射来自流体波导的电磁辐射的方法和装置。 本文提供用于改变波导芯或包层或两者的光学性质（例如，折射率，吸收和荧光）和/或物理性质（例如磁化率，导电性和温度）的各种方法。 在一个实施例中，电磁辐射是以多个不同的波长被引导和/或发射的，包括基本连续带形式的发射，在某些情况下覆盖至少150纳米。 在另一个实施例中，提供了用于在波导中分离波导芯和/或至少两个波导芯的接合的方法。 在另一个实施例中，本发明包括使用热梯度来产生波导和/或改变波导的性质。 波导的实施例可以用于光学检测或光谱分析。

    Elastomeric mask and use in fabrication of devices
    90.
    发明授权
    Elastomeric mask and use in fabrication of devices 有权
    弹性面膜和用于制造器件

    公开(公告)号：US07282240B1

    公开(公告)日：2007-10-16

    申请号：US09694074

    申请日：2000-10-20

    申请人： Rebecca J. Jackman ,  David C. Duffy ,  George M. Whitesides ,  Kathleen Vaeth ,  Klavs F. Jensen

    发明人： Rebecca J. Jackman ,  David C. Duffy ,  George M. Whitesides ,  Kathleen Vaeth ,  Klavs F. Jensen

    IPC分类号： B05D1/32

    CPC分类号： C23C14/042 ,  B82Y10/00 ,  B82Y30/00 ,  B82Y40/00 ,  G03F1/00 ,  G03F7/0002 ,  G03F7/0007 ,  G03F7/12 ,  H01L27/3211 ,  H01L27/3244 ,  H01L27/3281 ,  H01L51/0011 ,  H01L51/56

    摘要： An elastomeric mask is provided that allows deposition of a variety of materials through mask openings. The mask seals effectively against substrate surfaces, allowing simple deposition from fluid phase, gas phase, and the like or removal of material using gaseous or liquid etchants. The mask then can be simply peeled from the surface of the substrate leaving the patterned material behind. Multi-layered mask techniques are described in which openings in an upper mask allow selected openings of a lower mask to remain un-shielded, while other openings of the lower mask are shielded. A first deposition step, following by re-orientation of the upper mask to expose a different set of lower mask openings, allows selective deposition of different materials in different openings of the lower mask. Pixelated organic electroluminescent devices are provided via the described technique.

    摘要翻译： 提供了一种弹性体掩模，其允许通过掩模开口沉积各种材料。 掩模有效地密封衬底表面，允许从流体相，气相等简单沉积或使用气体或液体蚀刻剂去除材料。 然后可以从掩模的表面简单地剥离掩模，留下图案化材料。 描述了多层掩模技术，其中上掩模中的开口允许下掩模的选定开口保持未屏蔽，而下掩模的其它开口被屏蔽。 第一沉积步骤，随后通过上掩模的重新定向以暴露不同的一组下掩模开口，允许不同材料在下掩模的不同开口中的选择性沉积。 通过所述技术提供像素化的有机电致发光器件。