公开(公告)号：US20150206047A1

公开(公告)日：2015-07-23

申请号：US14159407

申请日：2014-01-20

Applicant: John Herslow ,  Adam Lowe

Inventor： John Herslow ,  Adam Lowe

IPC: G06K19/077 ,  H01Q7/00

CPC classification number: G06K19/07779 ,  G06K19/07771 ,  G06K19/07794 ,  H01Q1/2225 ,  H01Q7/00 ,  H01Q7/06

Abstract: A smart card with a metal layer which can capture radio-frequency (RF) signals via an antenna system is made operable by modifying the metal layer to enable passage of RF signals through the metal layer and/or by introducing a ferrite layer to enhance the efficient reception/transmission of RF signals by the antenna system. In one embodiment apertures are formed in and through the metal layer to allow RF signals to pass through the metal layer without negatively impacting the decorative or esthetic and/or reflective nature of the metal layer. These modifications allow for dual interface and contactless smart card formats. In other embodiments of the invention, a ferrite layer is formed between the metal layer and the inductors/antennas mounted within the smart card to enhance the efficient reception/transmission of RF signals.

Abstract translation: 具有能够通过天线系统捕获射频（RF）信号的金属层的智能卡通过修改金属层而可操作，以使得RF信号能够通过金属层和/或通过引入铁氧体层来增强 通过天线系统有效地接收/发射RF信号。 在一个实施例中，在金属层中并穿过金属层形成孔，以允许RF信号通过金属层，而不会不利地影响金属层的装饰性或美观性和/或反射性质。 这些修改允许双接口和非接触式智能卡格式。 在本发明的其它实施例中，在金属层和安装在智能卡内的电感器/天线之间形成铁氧体层，以增强RF信号的有效接收/传输。

公开(公告)号：US20050112619A1

公开(公告)日：2005-05-26

申请号：US10892403

申请日：2004-07-14

Applicant: Kenneth Livak ,  Adam Lowe ,  Andrew Blasband

Inventor： Kenneth Livak ,  Adam Lowe ,  Andrew Blasband

IPC: C12N15/09 ,  C12Q1/68 ,  G01N33/53 ,  G01N33/566 ,  C12P19/34

CPC classification number: C12Q1/6827 ,  C12Q1/6837 ,  C12Q1/6858 ,  C12Q1/6874 ,  C12Q2565/514 ,  C12Q2533/101 ,  C12Q2525/151 ,  C12Q2525/131 ,  C12Q2565/515 ,  C12Q2525/161 ,  C12Q2535/125 ,  C12Q2525/197 ,  C12Q2563/107

Abstract: Disclosed is a method for determining the number of repeat units in a repeat region of a target nucleic acid. In a first aspect, the method of the invention includes the steps of annealing a primer to a target nucleic acid; performing a first primer extension reaction using a first primer extension reagent; separating the target-primer hybrid and unreacted first primer extension reagent; performing a second primer extension reaction using a second primer extension reagent, wherein at least one of the first or second primer extension reagents includes an extendible nucleotide having a label attached thereto; separating the target-primer hybrid from unreacted second primer extension reagent; measuring a signal produced by the label; treating the label so as to render the label undetectable; and repeating the above steps until the signal is substantially less than a signal detected in a previous cycle. In a second aspect, the method of the invention includes the steps of annealing a primer to a target nucleic acid; performing a first primer extension reaction using a first primer-extension reagent; separating the target-primer hybrid from unreacted first primer extension reagent; performing a second primer extension reaction using a second primer extension reagent and with a primer termination reagent, the primer termination reagent including a nucleotide terminator having a label attached thereto; separating the target-primer hybrid from unreacted second primer extension reagent and unreacted primer termination reagent; measuring a signal produced by the label; and repeating the above steps until a signal is detected indicating incorporation of the nucleotide terminator. The invention further includes kits useful for practicing the above methods.

Abstract translation: 公开了确定靶核酸重复区域中重复单元数目的方法。 在第一方面，本发明的方法包括将引物退火至靶核酸的步骤; 使用第一引物延伸试剂进行第一引物延伸反应; 分离靶 - 引物杂交体和未反应的第一引物延伸试剂; 使用第二引物延伸试剂进行第二引物延伸反应，其中第一或第二引物延伸试剂中的至少一个包括具有附着标记的标记的可延伸核苷酸; 将靶引物杂交体与未反应的第二引物延伸试剂分离; 测量标签产生的信号; 处理标签以使标签不可检测; 并重复上述步骤，直到信号基本上小于在先前循环中检测到的信号。 在第二方面，本发明的方法包括将引物退火至靶核酸的步骤; 使用第一引物延伸试剂进行第一引物延伸反应; 将靶引物杂交体与未反应的第一引物延伸试剂分离; 使用第二引物延伸试剂和引物终止试剂进行第二引物延伸反应，所述引物终止试剂包括具有附着标记的核苷酸终止子; 从未反应的第二引物延伸试剂和未反应的引物终止试剂中分离靶引物杂交体; 测量标签产生的信号; 并重复上述步骤直到检测到指示掺入核苷酸终止子的信号。 本发明还包括可用于实践上述方法的试剂盒。

公开(公告)号：US20160180212A1

公开(公告)日：2016-06-23

申请号：US14977553

申请日：2015-12-21

Applicant: JOHN HERSLOW ,  ADAM LOWE ,  LUIS DASILVA

Inventor： JOHN HERSLOW ,  ADAM LOWE ,  LUIS DASILVA

IPC: G06K19/077 ,  H01Q1/52 ,  H01Q1/22 ,  H01Q7/00

CPC classification number: G06K19/07773 ,  G06K19/02 ,  G06K19/07771 ,  H01Q1/2225 ,  H01Q1/526 ,  H01Q7/06

Abstract: Ferrite material utilized in a smart metal card as a shield between a metal layer and an antenna does not occupy a complete layer. Instead, only sufficient ferrite material is utilized to track and conform to the antenna.

Abstract translation: 在智能金属卡中用作金属层和天线之间的屏蔽的铁素体材料不占据完整的层。 相反，仅使用足够的铁氧体材料来跟踪并符合天线。

公开(公告)号：US09390363B1

公开(公告)日：2016-07-12

申请号：US14639970

申请日：2015-03-05

Applicant: John Herslow ,  Adam Lowe ,  Luis Dasilva

Inventor： John Herslow ,  Adam Lowe ,  Luis Dasilva

IPC: G06K19/02 ,  G06K19/077 ,  B29C65/48 ,  B32B7/12 ,  B32B3/30 ,  B32B27/30 ,  B32B27/36 ,  B32B27/08 ,  B32B37/12 ,  B32B38/00 ,  B32B38/06 ,  B32B38/14 ,  B29C65/00 ,  B29C59/02 ,  G06K19/06 ,  B44C1/00 ,  B23K26/00 ,  B29K667/00 ,  B29K627/06 ,  B29L17/00

CPC classification number: G06K19/07722 ,  B29C59/026 ,  B29K2627/06 ,  B29K2667/003 ,  B29L2017/006 ,  B32B3/08 ,  B32B3/30 ,  B32B7/12 ,  B32B15/08 ,  B32B27/08 ,  B32B27/304 ,  B32B27/36 ,  B32B37/12 ,  B32B38/0008 ,  B32B38/06 ,  B32B38/14 ,  B32B38/145 ,  B32B2255/10 ,  B32B2255/205 ,  B32B2307/30 ,  B32B2307/402 ,  B32B2307/416 ,  B32B2307/584 ,  B32B2307/702 ,  B32B2307/75 ,  B32B2309/02 ,  B32B2310/0843 ,  B32B2311/00 ,  B32B2327/06 ,  B32B2367/00 ,  B32B2398/20 ,  B32B2425/00 ,  B32B2519/02 ,  B42D25/373 ,  B42D25/41 ,  B42D25/425 ,  B42D25/435 ,  B42D25/455 ,  B42D25/46 ,  G06K19/06187 ,  G06K19/07775

Abstract: A multi layered card embodying the invention includes an outer layer of an amorphous laser reactive copolymer material which is embossed with a selected pattern at a selected temperature which is above the glass transition temperature, Tg, of the copolymer and below its melting temperature, Tm. So embossed, the selected pattern is set in the copolymer layer, and its external shape cannot be changed from the embossed form to which it was set at the selected temperature, without destroying the selected pattern. The outer layer may be laminated with the other layers of the card and laser engraved before or after lamination.

Abstract translation: 实施本发明的多层卡包括非晶态激光反应性共聚物材料的外层，该外层在选定的温度下被压印，所述选定的温度高于共聚物的玻璃化转变温度Tg，并低于其熔融温度Tm。 所以压花，所选择的图案被设置在共聚物层中，并且其外部形状不能从其被设置在所选择的温度下的压纹形式改变，而不会破坏所选择的图案。 外层可以与层叠的其它层和层压之前或之后的激光雕刻层压。

公开(公告)号：US09390366B1

公开(公告)日：2016-07-12

申请号：US14793963

申请日：2015-07-08

Applicant: John Herslow ,  Adam Lowe ,  Luis Dasilva ,  Brian Nester

Inventor： John Herslow ,  Adam Lowe ,  Luis Dasilva ,  Brian Nester

IPC: G06K19/06 ,  G06K19/077 ,  H01L25/00

CPC classification number: G06K19/07769 ,  H01L23/3121 ,  H01L2223/6677 ,  H01L2924/14 ,  H01L2924/15313

Abstract: A dual interface smart card having a metal layer includes an IC module, with contacts and RF capability, mounted on a plug, formed of non RF impeding material, between the top and bottom surfaces of the metal layer. The plug provides support for the IC module and a degree of electrical insulation and isolation from the metal layer. The resultant card can have contact and contactless operating capability and an entirely smooth external metal surface except for the contacts of the IC module.

Abstract translation: 具有金属层的双接口智能卡包括在金属层的顶表面和底表面之间安装在由无RF阻挡材料形成的插头上的触点和RF能力的IC模块。 插头提供对IC模块的支持和与金属层的电绝缘和隔离度。 所得到的卡可以具有接触和非接触操作能力以及除了IC模块的触点之外的完全平滑的外部金属表面。

公开(公告)号：US20150339564A1

公开(公告)日：2015-11-26

申请号：US14718596

申请日：2015-05-21

Applicant: JOHN HERSLOW ,  Adam Lowe ,  Luis Dasilva

Inventor： JOHN HERSLOW ,  Adam Lowe ,  Luis Dasilva

IPC: G06K19/077 ,  C25D3/46 ,  C25D3/48 ,  C25D3/50 ,  B32B38/00 ,  B32B9/02 ,  B32B9/00 ,  B32B15/20 ,  B32B3/30 ,  B32B3/14 ,  B32B27/38 ,  B32B27/18 ,  B32B37/12 ,  B32B37/18 ,  B32B38/06 ,  B32B38/10 ,  B32B38/14 ,  G06K19/02 ,  C25D7/00

CPC classification number: G06K19/07722 ,  B32B3/04 ,  B32B3/08 ,  B32B3/14 ,  B32B3/30 ,  B32B7/12 ,  B32B9/00 ,  B32B9/005 ,  B32B9/02 ,  B32B9/025 ,  B32B9/04 ,  B32B9/041 ,  B32B9/042 ,  B32B9/045 ,  B32B9/047 ,  B32B13/04 ,  B32B13/06 ,  B32B13/12 ,  B32B15/04 ,  B32B15/043 ,  B32B15/08 ,  B32B15/10 ,  B32B15/14 ,  B32B15/20 ,  B32B21/00 ,  B32B21/04 ,  B32B21/08 ,  B32B21/14 ,  B32B27/08 ,  B32B27/12 ,  B32B27/18 ,  B32B27/36 ,  B32B27/38 ,  B32B33/00 ,  B32B37/12 ,  B32B37/18 ,  B32B38/0012 ,  B32B38/06 ,  B32B38/10 ,  B32B38/105 ,  B32B38/14 ,  B32B38/145 ,  B32B2038/0016 ,  B32B2250/03 ,  B32B2250/04 ,  B32B2255/00 ,  B32B2255/06 ,  B32B2255/08 ,  B32B2255/10 ,  B32B2255/20 ,  B32B2255/205 ,  B32B2264/108 ,  B32B2307/40 ,  B32B2307/402 ,  B32B2307/584 ,  B32B2307/732 ,  B32B2311/24 ,  B32B2313/04 ,  B32B2315/02 ,  B32B2317/08 ,  B32B2317/16 ,  B32B2363/00 ,  B32B2425/00 ,  C25D3/46 ,  C25D3/48 ,  C25D3/50 ,  C25D5/022 ,  C25D7/00 ,  C25D11/04 ,  C25D11/18 ,  C25D11/243 ,  C25D11/246 ,  C25D11/26 ,  C25D11/34 ,  G06K19/02 ,  G06K19/022 ,  Y10T29/49004 ,  Y10T29/49828 ,  Y10T156/10 ,  Y10T156/1039 ,  Y10T156/1082

Abstract: Cards made in accordance with the invention include a specially treated thin decorative layer attached to a thick core layer of metal or ceramic material, where the thin decorative layer is designed to provide selected color(s) and/or selected texture(s) to a surface of the metal cards. Decorative layers for use in practicing the invention include: (a) an anodized metal layer; or (b) a layer of material derived from plant or animal matter (e.g., wood, leather); or (c) an assortment of aggregate binder material (e.g., cement, mortar, epoxies) mixed with laser reactive materials (e.g., finely divided carbon); or (d) a ceramic layer; and (e) a layer of crystal fabric material. The cards may be dual interface smart cards which can be read in a contactless manner and/or via contacts.

Abstract translation: 根据本发明制造的卡包括附着在金属或陶瓷材料的厚芯层上的经特殊处理的薄装饰层，其中薄装饰层被设计成将选定的颜色和/或所选纹理提供给 表面的金属卡片。 用于实施本发明的装饰层包括：（a）阳极化金属层; 或（b）衍生自植物或动物物质（例如木材，皮革）的材料层; 或（c）与激光反应性材料（例如细碎碳）混合的各种聚集的粘合剂材料（例如，水泥，砂浆，环氧树脂）; 或（d）陶瓷层; 和（e）一层水晶织物材料。 这些卡可以是双接口智能卡，其可以以非接触式方式和/或经由触点读取。

公开(公告)号：US20070178519A1

公开(公告)日：2007-08-02

申请号：US11731192

申请日：2007-03-30

Applicant: Kenneth Livak ,  Adam Lowe ,  Andrew Blasband

Inventor： Kenneth Livak ,  Adam Lowe ,  Andrew Blasband

IPC: C12Q1/68 ,  C12P19/34 ,  C07H21/04

CPC classification number: C12Q1/6827 ,  C12Q1/6837 ,  C12Q1/6858 ,  C12Q1/6874 ,  C12Q2565/514 ,  C12Q2533/101 ,  C12Q2525/151 ,  C12Q2525/131 ,  C12Q2565/515 ,  C12Q2525/161 ,  C12Q2535/125 ,  C12Q2525/197 ,  C12Q2563/107

Abstract: Disclosed is a method for determining the number of repeat units in a repeat region of a target nucleic acid. In a first aspect, the method of the invention includes the steps of annealing a primer to a target nucleic acid; performing a first primer extension reaction using a first primer extension reagent; separating the target-primer hybrid and unreacted first primer extension reagent; performing a second primer extension reaction using a second primer extension reagent, wherein at least one of the first or second primer extension reagents includes an extendible nucleotide having a label attached thereto; separating the target-primer hybrid from unreacted second primer extension reagent; measuring a signal produced by the label; treating the label so as to render the label undetectable; and repeating the above steps until the signal is substantially less than a signal detected in a previous cycle. In a second aspect, the method of the invention includes the steps of annealing a primer to a target nucleic acid; performing a first primer extension reaction using a first primer-extension reagent; separating the target-primer hybrid from unreacted first primer extension reagent; performing a second primer extension reaction using a second primer extension reagent and with a primer termination reagent, the primer termination reagent including a nucleotide terminator having a label attached thereto; separating the target-primer hybrid from unreacted second primer extension reagent and unreacted primer termination reagent; measuring a signal produced by the label; and repeating the above steps until a signal is detected indicating incorporation of the nucleotide terminator. The invention further includes kits useful for practicing the above methods.

Abstract translation: 公开了确定靶核酸重复区域中重复单元数目的方法。 在第一方面，本发明的方法包括将引物退火至靶核酸的步骤; 使用第一引物延伸试剂进行第一引物延伸反应; 分离靶 - 引物杂交体和未反应的第一引物延伸试剂; 使用第二引物延伸试剂进行第二引物延伸反应，其中第一或第二引物延伸试剂中的至少一个包括具有附着标记的标记的可延伸核苷酸; 将靶引物杂交体与未反应的第二引物延伸试剂分离; 测量标签产生的信号; 处理标签以使标签不可检测; 并重复上述步骤，直到信号基本上小于在先前循环中检测到的信号。 在第二方面，本发明的方法包括将引物退火至靶核酸的步骤; 使用第一引物延伸试剂进行第一引物延伸反应; 将靶引物杂交体与未反应的第一引物延伸试剂分离; 使用第二引物延伸试剂和引物终止试剂进行第二引物延伸反应，所述引物终止试剂包括具有附着标记的核苷酸终止子; 从未反应的第二引物延伸试剂和未反应的引物终止试剂中分离靶引物杂交体; 测量标签产生的信号; 并重复上述步骤直到检测到指示掺入核苷酸终止子的信号。 本发明还包括可用于实践上述方法的试剂盒。