摘要:
A wind turbine blade with a lightning protection for a blade with a shell body has at least one lightning receptor arranged freely accessible in or on a surface of the shell body surface, and a lightning down conductor electrically connected to the lightning receptor and comprising an inner conductor made of electrically conductive material imbedded in a bedding insulation made of an electrically non-conductive material. The lightning down conductor further includes a first conductive layer having a resistance in the range of 10 to 10,000 Mega Ohm per meter (MΩ/m). The first conductive layer is located in a transverse distance from the inner conductor and being electrically isolated from the inner conductor.
摘要:
An elongate probe (204) including a probe head (214) with a transducer array (216), a shaft (210) and an articulating member (212). The articulating member is located between the probe head and the shaft. The articulating member is configured to articulate between a position in which the probe head extends along a longitudinal axis of the probe and at least one articulated position in which the probe head extends at a non-zero angle from the longitudinal axis of the probe. The probe further includes a stiffener (224) configured to controllably move from a retracted position to an extended position at which the stiffener inhibits articulation of the articulating member.
摘要:
A method of manufacturing a fiber-reinforced blade for a wind energy plant is presented, which blade is configured with at least a blade shell and means for conducting to a lightning current to an earth connection. Novel aspects of the method comprise that the blade is provided with segmented conductor means that are configured for conducting a lightning current outside the blade to the means for conducting to earth; and wherein the conductor means are distributed and secured at the external surface of the blade shell in such a manner that the conductor means are essentially flush with the external surface of the blade shell. When the segmented conductor means are distributed and attached at the external surface of the blade shell, the lightning current will not have to be conducted through the conductor means, but rather they are conducted in a ionised passage in the air above the conductor means.
摘要:
The invention relates to modified polypeptides with reduced allergenicity comprising a parent polypeptide with a molecular weight from between 10 kDa and 100 kDa conjugated to a polymer with a molecular weight (M.sub.r) in the range of 1 kDa and 60 kDa. The modified polypeptide are produced using a process including the step of conjugating from 1 to 30 polymer molecules with the parent polypeptide. Further the invention relates to compositions comprising said polypeptides and further ingredients normally used in e.g. detergents, including dishwashing detergents and soap bars, household article, agrochemicals, personal care products, cosmetics, toiletries, oral and dermal pharmaceuticals, composition for treating textiles, and compositions used for manufacturing food and feed. Finally the invention is directed to uses of polypeptides with reduced allergenicity or compositions thereof for reducing the allergenicity of productsfor a vast number of industrial applications.
摘要:
The invention relates to a wind turbine blade with a lightning protection system, the lightning protection system comprises at least one lightning receptor arranged freely accessible in or on the shell unit surface at or in the immediate vicinity of the tip of the blade. The lightning protection system further comprises a lightning down conductor made of electrically conductive material extending within the shell body from the lightning receptor to the root end of the blade. The lightning receptor and the lightning down conductor are electrically connected. The shell body comprises at least a first conductive layer extending along at least a longitudinal part of the lightning down conductor in a transverse distance therefrom. The first conductive layer is electrically isolated from the lightning down conductor and from the lightning receptor, and has a sheet resistance in the range 1-5 Mega Ohm per square.
摘要:
The present disclosure concerns LNA oligonucleotides having a (sub)sequence of the general formula 5′-(MeCx)(Tx)MeCxAsAstscscsastsgsgsMeCxAx(Gx)(c)-3′, and preferably of the general formula 5′-MeCxTxMeCxAsastscscsastsgsgsMeCxAxGxc-3′, wherein capital letters designate an LNA nucleotide analogue selected from β-D-oxy-LNA, β-D-thio-LNA, β-D-amino-LNA and α-L-oxy-LNA, small letters designate a deoxynucleotide, and underline designates either an LNA nucleotide analogue as defined above or a deoxynucleotide. Such LNA oligonucleotides exhibit surprisingly good properties with respect to inhibition of the expression of Survivin by means of an anti-sense mechanism, and thereby lead to reduction or inhibition of tumor development in vivo. The LNA oligonucleotides are superior to other LNA oligonucleotides targeting Surviving mRNA measured by functional read outs such as apoptosis induction and proliferation inhibition, and is potent in down-regulating Survivin mRNA and protein in transfected cancer cell lines, and induce apoptosis in combination with Taxol superior compared to other LNA oligonucleotides.
摘要翻译:本公开涉及具有通式5' - (MeC x)(Tx)MeC x As A stscscsastsgsgsMeC x A x(G x)(c)-3'的(亚)序列的LNA寡核苷酸,优选通式为5'-MeCxTxMeCxAsastscscsastsgsgsMeCxAxGxc-3' 其中大写字母表示选自以下的LNA核苷酸类似物:-D-oxy-LNA,&bgr; -D-thio-LNA,&bgr; -D-氨基-LNA和α-L-氧-LNA,小字母表示脱氧核苷酸 ,下划线表示如上定义的LNA核苷酸类似物或脱氧核苷酸。 这样的LNA寡核苷酸在通过反义机制抑制存活蛋白的表现方面表现出惊人的良好性质,从而导致体内肿瘤发展的减少或抑制。 LNA寡核苷酸优于靶向通过功能读数如凋亡诱导和增殖抑制测定的存活mRNA的其他LNA寡核苷酸,并且在转染的癌细胞系中下调存活蛋白mRNA和蛋白质的有效性,并且与紫杉醇优良结合诱导凋亡 与其他LNA寡核苷酸相比。
摘要:
The present invention concerns a method of producing a lightning diverter for conducting a lightning-induced electrical current, which is to be placed on structures such as wings on wind turbines, aircraft components, radomes and the like with the purpose of lightning protection. The method comprises the steps of making a plurality of holes in a plate of an electrically conductive material, filling said holes at least partly with one or more electrically non-conductive materials, and then finally dividing the plate—preferably into strips. The lightning diverter obtained hereby consists of a layer of electrically non-conductive material with a plurality of isolated segments of electrically conductive material.The invention further relates to a diverter strip with isolated segments of concave shapes being advantageous because of the good connection between the segments and the non-conductive material.
摘要:
Oligonucleotides directed against the survivin gene are provided for modulating the expression of survivin. The compositions comprise oligonucleotides, particularly antisense oligonucleotides, targeted to nucleic acids encoding the survivin. Methods of using these compounds for modulation of survivin expression and for the treatment of diseases associated with either overexpression of survivin, expression of mutated survivin or both are provided. Examples of diseases are cancer such as lung, breast, colon, prostate, pancreas, lung, liver, thyroid, kidney, brain, testes, stomach, intestine, bowel, spinal cord, sinuses, bladder, urinary tract or ovaries cancers. The oligonucleotides may be composed of deoxyribonucleosides or a nucleic acid analogue such as for example locked nucleic acid or a combination thereof.
摘要:
The invention relates to a method of lightning-proofing a blade (1) on a wind-energy plant, which blade comprises a blade shell (2) configured essentially as a fiber-reinforced laminate, which laminate comprises electrically conductive fibers, wherein the blade comprises at least one lightning arrester (9) configured for conducting lightning current, including preferably to ground. The method comprises that the electrically conductive fibers are connected to each other, and that at least one metallic receptor (4, 24, 25) is arranged for capturing lightning current at or in proximity of the external face of the blade; and that the receptor and the fibers are connected to the lightning arrester for equalizing the difference in potential between the lightning arrester and the electrically conductive fibers. When the electrically conductive fibers are connected to each other, the fibers will cooperate on the conduction of a possible lightning current to prevent the current from running in individual fibers. Simultaneously the metallic receptor will serve as the primary lightning capturing device and reduce the risk of lightning striking the laminate. The receptor being connected to the lightning arrester, the current will predominately be conducted to ground, while the risk of transfer to the laminate is minimized in that a possible difference in potential between fibers and lightning arrester has been equalized.
摘要:
A method for the mixing of fluid streams in a duct comprising positioning at least one mixing device having a front side and a back side within said duct through which a first major stream travels, the at least one mixing device determining a total cross-sectional area which is significantly lower than that of the duct so as to allow for the passage of said first major stream, whereby the at least one mixing device is a solid plate provided with one or more protrusions extending outward from the main solid plate body.