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公开(公告)号：US20120108509A1
公开(公告)日：2012-05-03
申请号：US13282332
申请日：2011-10-26
IPC分类号： A61K31/722 , A61K31/737 , A61K38/02 , A61K31/7088 , A61K38/19 , A61P29/00 , A61P31/10 , A61P33/00 , A61P31/12 , A61P31/00 , A61P35/00 , A61P11/02 , A61P37/06 , A61P11/00 , A61K31/728
CPC分类号： A61L24/043 , A61L26/0052 , A61L2300/00 , C08L1/00 , C08L3/04 , C08L3/10 , C08L5/00 , C08L5/08
摘要： Body tissue and structures in an airway may be treated with an artificial scab comprising an inhomogeneous, uncohesive, solid sheet-like body comprising a granular mixture of chitosan and polysaccharide particles. The artificial scab breaks apart into smaller pieces if peeled away from the surgical site or wound, thus reducing the risk of airway occlusion.
摘要翻译： 气道中的身体组织和结构可以用包含壳聚糖和多糖颗粒的颗粒混合物的不均匀的，非粘性的固体片状体的人造痂来治疗。 如果从外科手术部位或伤口剥离，则人造痂骨分裂成更小的部件，从而降低气道闭塞的风险。
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2.发明授权Solvating system and sealant for medical use in the sinuses and nasal passages 有权用于鼻窦和鼻通道的医疗用溶剂系统和密封剂公开(公告)号：US07993675B2
公开(公告)日：2011-08-09
申请号：US11739480
申请日：2007-04-24
申请人： Dana A. Oliver , Cecil O. Lewis , Edze Jan Tijsma , Maria Nieves Gonzalez Lopez , Matthew F. Myntti , James Britton Hissong
发明人： Dana A. Oliver , Cecil O. Lewis , Edze Jan Tijsma , Maria Nieves Gonzalez Lopez , Matthew F. Myntti , James Britton Hissong
IPC分类号： A61K9/00
CPC分类号： A61K9/0043 , A61K9/7007
摘要： Chronic rhinosinusitis and other bacterial sinus conditions may be treated by applying a solvating system containing a surfactant to a bacterial biofilm in a nasal or sinus cavity, disrupting the biofilm, and applying a protective layer of a polymeric film-forming medical sealant.
摘要翻译： 可以通过将包含表面活性剂的溶剂化体系应用于鼻腔或窦腔中的细菌生物膜，破坏生物膜和施加聚合物成膜医用密封剂的保护层来治疗慢性鼻鼻窦炎和其它细菌窦状况。
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公开(公告)号：US07890178B2
公开(公告)日：2011-02-15
申请号：US11611365
申请日：2006-12-15
申请人： Roy L. Testerman , Jon P. Davis , Nathan Andrew Torgerson , Robyn Lee Jagler , James Britton Hissong
发明人： Roy L. Testerman , Jon P. Davis , Nathan Andrew Torgerson , Robyn Lee Jagler , James Britton Hissong
IPC分类号： A61N1/08
CPC分类号： A61N1/36007 , A61N1/04 , A61N1/0504 , A61N1/0526 , A61N1/0556 , A61N1/36017 , A61N1/36085
摘要： Artificially stimulated deglutition methods and systems including providing a portable system born by a user for controlling a component of a complete swallowing act without substantial aspiration. The system includes a controller, a signal generator, and a subcutaneously positioned electrode array with at least one electrode. The electrode array is subcutaneously positioned and is operated to stimulate a single deglutition muscle where the single deglutition muscle is the only deglutition muscle directly artificially stimulated via the electrode array during the complete swallowing act. Systems and methods of nerve stimulation and selective nerve stimulation are also provided to artificially stimulate deglutition.
摘要翻译： 人为刺激的吞咽方法和系统，包括提供由用户产生的便携式系统，用于控制完全吞咽作用的组分而没有实质的吸入。 该系统包括控制器，信号发生器和具有至少一个电极的皮下定位的电极阵列。 电极阵列被皮下定位并且被操作以刺激单一的消除肌肉，其中单个消除肌肉是完全吞咽期间直接通过电极阵列人造刺激的唯一的消除肌肉。 还提供神经刺激和选择性神经刺激的系统和方法以人为刺激吞咽。
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公开(公告)号：US20080147142A1
公开(公告)日：2008-06-19
申请号：US11611367
申请日：2006-12-15
申请人： Roy L. Testerman , Jon P. Davis , Nathan Andrew Torgerson , Robyn Lee Jagler , James Britton Hissong , Christy Ludlow , Pamela Reed Kearney
发明人： Roy L. Testerman , Jon P. Davis , Nathan Andrew Torgerson , Robyn Lee Jagler , James Britton Hissong , Christy Ludlow , Pamela Reed Kearney
CPC分类号： A61N1/36007
摘要： Methods and systems for artificially stimulating user deglutition without substantial aspiration are provided. Methods and systems include artificially stimulating user deglutition according to various specialized programs, including passive user secretion maintenance programs, active feeding programs, proprioceptive feedback programs, and others.
摘要翻译： 提供了无需大量抽吸的人工刺激用户吞咽的方法和系统。 方法和系统包括根据各种专门程序人为刺激用户吞咽，包括被动用户分泌维护程序，主动喂养程序，本体感受反馈程序等。
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5.发明申请SOLVATING SYSTEM AND SEALANT FOR MEDICAL USE IN THE SINUSES AND NASAL PASSAGES 有权用于医疗用途和鼻腔通道的溶解系统和密封剂公开(公告)号：US20070264342A1
公开(公告)日：2007-11-15
申请号：US11739480
申请日：2007-04-24
申请人： Dana A. Oliver , Cecil O. Lewis , Edze Jan Tijsma , Maria Nieves Gonzalez Lopez , Matthew F. Myntti , James Britton Hissong
发明人： Dana A. Oliver , Cecil O. Lewis , Edze Jan Tijsma , Maria Nieves Gonzalez Lopez , Matthew F. Myntti , James Britton Hissong
IPC分类号： A61K9/00
CPC分类号： A61K9/0043 , A61K9/7007
摘要： Chronic rhinosinusitis and other bacterial sinus conditions may be treated by applying a solvating system containing a surfactant to a bacterial biofilm in a nasal or sinus cavity, disrupting the biofilm, and applying a protective layer of a polymeric film-forming medical sealant.
摘要翻译： 可以通过将包含表面活性剂的溶剂化体系应用于鼻腔或窦腔中的细菌生物膜，破坏生物膜和施加聚合物成膜医用密封剂的保护层来治疗慢性鼻鼻窦炎和其它细菌窦状况。
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公开(公告)号：US09037226B2
公开(公告)日：2015-05-19
申请号：US12896578
申请日：2010-10-01
申请人： David C. Hacker , Maria Charles Vijay Stanislaus , Wenjeng Li , Dwayne S. Yamasaki , William C. Brunnett , Kevin L. McFarlin , James Britton Hissong , Robert K. Vaccaro , John M. Murphy , Carla A. Pagotto , Tino Schuler
发明人： David C. Hacker , Maria Charles Vijay Stanislaus , Wenjeng Li , Dwayne S. Yamasaki , William C. Brunnett , Kevin L. McFarlin , James Britton Hissong , Robert K. Vaccaro , John M. Murphy , Carla A. Pagotto , Tino Schuler
IPC分类号： A61B5/00 , A61B5/0488 , A61B1/00 , A61B1/267 , A61M16/04 , A61N1/05 , A61B5/0492 , A61B5/042 , A61B1/005 , A61B1/015 , A61B1/018 , A61B5/06
CPC分类号： A61B5/6853 , A61B1/00082 , A61B1/00147 , A61B1/005 , A61B1/015 , A61B1/018 , A61B1/04 , A61B1/07 , A61B1/267 , A61B1/2673 , A61B5/01 , A61B5/04012 , A61B5/0421 , A61B5/0488 , A61B5/04886 , A61B5/0492 , A61B5/062 , A61B5/064 , A61B5/065 , A61B5/07 , A61B5/11 , A61B2562/0209 , A61B2562/0215 , A61B2562/0219 , A61B2562/0261 , A61B2562/046 , A61M16/04 , A61M16/0411 , A61M16/0434 , A61M16/0443 , A61M16/0445 , A61M16/0459 , A61M16/0463 , A61M16/0488 , A61M16/0825 , A61M2205/0233 , A61M2205/0294 , A61M2205/3306 , A61M2205/332 , A61M2205/3344 , A61M2205/3368 , A61M2205/3546 , A61M2205/3569 , A61M2205/3592 , A61M2205/6054 , A61M2210/065 , A61M2230/08 , A61N1/0517 , A61N1/0519
摘要： An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive ink electrodes are formed on the exterior surface of the endotracheal tube. The conductive ink electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least one conductor is coupled to the conductive ink electrodes and is configured to carry the EMG signals received by the conductive ink electrodes to a processing apparatus.
摘要翻译： 用于监测患者喉部肌肉的EMG信号的装置包括具有外表面的气管内管。 导电墨水电极形成在气管内管的外表面上。 导电油墨电极构造成当气管内导管放置在患者的气管中时从喉部肌肉接收EMG信号。 至少一个导体耦合到导电墨水电极并且被配置为将由导电墨水电极接收的EMG信号传送到处理装置。
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公开(公告)号：US20120184926A1
公开(公告)日：2012-07-19
申请号：US13323636
申请日：2011-12-12
CPC分类号： A61L26/0047 , A61L24/0015 , A61L24/0042 , A61L24/108 , A61L26/0014 , A61L26/0019 , A61L26/0023 , A61L26/0066 , A61L31/047 , A61L31/148 , A61L31/16 , A61L2300/402 , A61L2300/404 , A61L2300/41 , A61L2300/412 , A61L2300/416 , A61L2400/04 , C09J133/14 , C09J139/06 , C09J167/00 , C09J167/04 , C09J169/00 , C09J175/04 , C09J177/00 , C09J179/02 , C09J185/02
摘要： The invention provides a polymeric medical sealant. The medical sealant is useful for application to the tonsils and adenoids, wherein the sealant performs at least one of the following functions, a) inhibit the colonization of bacteria, b) inhibit the binding of bacteria to tissue, c) reduction of tissue morbidity, d) hemostasis, e) coating and protection of tissue during healing. f) promotion of healing, and g) reduction of pain.
摘要翻译： 本发明提供一种聚合物医用密封剂。 医用密封剂可用于扁桃体和腺样体，其中密封剂具有以下功能中的至少一个：a）抑制细菌的定居，b）抑制细菌与组织的结合，c）减少组织发病率， d）止血，e）愈合过程中涂层和保护组织。 f）促进愈合，g）减轻疼痛。
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公开(公告)号：US20110190596A1
公开(公告)日：2011-08-04
申请号：US12896578
申请日：2010-10-01
申请人： David C. Hacker , Maria Charles Vijay Stanislaus , Wenjeng Li , Dwayne S. Yamasaki , William C. Brunnett , Kevin L. McFarlin , James Britton Hissong , Robert K. Vaccaro , John M. Murphy , Carla A. Pagotto , Tino Schuler
发明人： David C. Hacker , Maria Charles Vijay Stanislaus , Wenjeng Li , Dwayne S. Yamasaki , William C. Brunnett , Kevin L. McFarlin , James Britton Hissong , Robert K. Vaccaro , John M. Murphy , Carla A. Pagotto , Tino Schuler
IPC分类号： A61B5/0492 , A61B5/01 , A61B5/11
CPC分类号： A61B5/6853 , A61B1/00082 , A61B1/00147 , A61B1/005 , A61B1/015 , A61B1/018 , A61B1/04 , A61B1/07 , A61B1/267 , A61B1/2673 , A61B5/01 , A61B5/04012 , A61B5/0421 , A61B5/0488 , A61B5/04886 , A61B5/0492 , A61B5/062 , A61B5/064 , A61B5/065 , A61B5/07 , A61B5/11 , A61B2562/0209 , A61B2562/0215 , A61B2562/0219 , A61B2562/0261 , A61B2562/046 , A61M16/04 , A61M16/0411 , A61M16/0434 , A61M16/0443 , A61M16/0445 , A61M16/0459 , A61M16/0463 , A61M16/0488 , A61M16/0825 , A61M2205/0233 , A61M2205/0294 , A61M2205/3306 , A61M2205/332 , A61M2205/3344 , A61M2205/3368 , A61M2205/3546 , A61M2205/3569 , A61M2205/3592 , A61M2205/6054 , A61M2210/065 , A61M2230/08 , A61N1/0517 , A61N1/0519
摘要： An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive ink electrodes are formed on the exterior surface of the endotracheal tube. The conductive ink electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least one conductor is coupled to the conductive ink electrodes and is configured to carry the EMG signals received by the conductive ink electrodes to a processing apparatus.
摘要翻译： 用于监测患者喉部肌肉的EMG信号的装置包括具有外表面的气管内管。 导电墨水电极形成在气管内管的外表面上。 导电油墨电极构造成当气管内导管放置在患者的气管中时从喉部肌肉接收EMG信号。 至少一个导体耦合到导电墨水电极并且被配置为将由导电墨水电极接收的EMG信号传送到处理装置。
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公开(公告)号：US20080147141A1
公开(公告)日：2008-06-19
申请号：US11611365
申请日：2006-12-15
申请人： Roy L. Testerman , Jon P. Davis , Nathan Andrew Torgerson , Robyn Lee Jagler , James Britton Hissong
发明人： Roy L. Testerman , Jon P. Davis , Nathan Andrew Torgerson , Robyn Lee Jagler , James Britton Hissong
CPC分类号： A61N1/36007 , A61N1/04 , A61N1/0504 , A61N1/0526 , A61N1/0556 , A61N1/36017 , A61N1/36085
摘要： Artificially stimulated deglutition methods and systems including providing a portable system born by a user for controlling a component of a complete swallowing act without substantial aspiration. The system includes a controller, a signal generator, and a subcutaneously positioned electrode array with at least one electrode. The electrode array is subcutaneously positioned and is operated to stimulate a single deglutition muscle where the single deglutition muscle is the only deglutition muscle directly artificially stimulated via the electrode array during the complete swallowing act. Systems and methods of nerve stimulation and selective nerve stimulation are also provided to artificially stimulate deglutition.
摘要翻译： 人为刺激的吞咽方法和系统，包括提供由用户产生的便携式系统，用于控制完全吞咽作用的组分而没有实质的吸入。 该系统包括控制器，信号发生器和具有至少一个电极的皮下定位的电极阵列。 电极阵列被皮下定位并且被操作以刺激单一的消除肌肉，其中单个消除肌肉是完全吞咽期间直接通过电极阵列人造刺激的唯一的消除肌肉。 还提供神经刺激和选择性神经刺激的系统和方法以人为刺激吞咽。
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公开(公告)号：US09700648B2
公开(公告)日：2017-07-11
申请号：US13282332
申请日：2011-10-26
IPC分类号： A61K31/722 , A61K31/737 , A61K38/02 , A61K31/7088 , A61K38/19 , A61P29/00 , A61P31/10 , A61P33/00 , A61P31/12 , A61P31/00 , A61P35/00 , A61P11/02 , A61P37/06 , A61P11/00 , A61K31/728 , A61L24/04 , C08L3/10 , C08L3/04 , C08L5/00 , C08L5/08 , C08L1/00 , A61L26/00
CPC分类号： A61L24/043 , A61L26/0052 , A61L2300/00 , C08L1/00 , C08L3/04 , C08L3/10 , C08L5/00 , C08L5/08
摘要： Body tissue and structures in an airway may be treated with an artificial scab comprising an inhomogeneous, uncohesive, solid sheet-like body comprising a granular mixture of chitosan and polysaccharide particles. The artificial scab breaks apart into smaller pieces if peeled away from the surgical site or wound, thus reducing the risk of airway occlusion.
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