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公开(公告)号：US20050069877A1
公开(公告)日：2005-03-31
申请号：US10480988
申请日：2002-06-18
申请人： Ameena Gandhi , Amy Kable , Anita Swarnakar , April Hafalia , Bao Tran , Brendan Duggan
发明人： Ameena Gandhi , Amy Kable , Anita Swarnakar , April Hafalia , Bao Tran , Brendan Duggan
IPC分类号： A01K67/027 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/04 , A61P9/00 , A61P9/10 , A61P15/00 , A61P15/08 , A61P17/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07H21/04 , C07K14/47 , C07K16/18 , C07K16/40 , C07K16/42 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/02 , C12N9/12 , C12N9/16 , C12N9/48 , C12N9/50 , C12N9/64 , C12N9/90 , C12N15/09 , C12P21/02 , C12P21/06 , C12P21/08 , C12Q1/02 , C12Q1/26 , C12Q1/37 , C12Q1/42 , C12Q1/48 , C12Q1/533 , C12Q1/68 , G01N33/15 , G01N33/50 , G01N33/53 , G01N33/566 , G01N37/00
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00
摘要： Various embodiments of the invention provide human proteinmodification and maintenance molecules (PMOD) and polynucleotides which identify and encode PMOD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, andantagonists. Other embodiments provide methods for diagnosing, eating, or preventing disorders associated with aberrant expression of PMOD.
摘要翻译： 本发明的各种实施方案提供鉴定和编码PMOD的人蛋白质修饰和维持分子（PMOD）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，进食或预防与异常PMOD表达相关的紊乱的方法。
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公开(公告)号：US20050107588A1
公开(公告)日：2005-05-19
申请号：US10495148
申请日：2002-11-13
申请人： Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
发明人： Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
IPC分类号： C07K14/47 , C07K14/705 , C07H21/04
CPC分类号： C07K14/705 , C07K14/47
摘要： Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, anti-bodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与REMAP异常表达相关的紊乱的方法。
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公开(公告)号：US20070092885A1
公开(公告)日：2007-04-26
申请号：US11378616
申请日：2006-03-20
申请人： Henry Yue , Monique Yao , Ameena Gandhi , Mariah Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan Sanjanwala , Michael Thornton , Vicki Elliott , Yan Lu , Kimberly Gietzen , Neil Burford , Li Ding , April Hafalia , Y. Tang , Olga Bandman , Bridget Warren , Cynthia Honchell , Dyung Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti Lal , Bao Tran , Craig Ison , Brendan Duggan , Stephanie Sapperstein
发明人： Henry Yue , Monique Yao , Ameena Gandhi , Mariah Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan Sanjanwala , Michael Thornton , Vicki Elliott , Yan Lu , Kimberly Gietzen , Neil Burford , Li Ding , April Hafalia , Y. Tang , Olga Bandman , Bridget Warren , Cynthia Honchell , Dyung Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti Lal , Bao Tran , Craig Ison , Brendan Duggan , Stephanie Sapperstein
CPC分类号： C12N15/1055 , A61K39/3955 , A61K47/64 , A61K47/643 , A61K2039/505 , C07K14/47 , C07K14/4711 , C07K14/4713 , C07K16/18 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/75 , C07K2317/76 , G01N33/5023
摘要： The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
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公开(公告)号：US20050033018A1
公开(公告)日：2005-02-10
申请号：US10477714
申请日：2002-05-16
申请人： Preeti Lal , Bridget Warren , Yuming Xu , Brendan Duggan , Cynthia Honchell , Deborah Kallick , Mariah Baughn , Y. Tang , Henry Yue , Olga Bandman , Karen Jones , Shanya Becha , Uyen Tran , Janice Au-Young , Jennifer Griffin , Yeganeh Zebarjadian , Ernestie Lee , Vicki Elliott , Kavitha Thangavelu , Jayalaxmi Ramkumar , Yan Lu , April Hafalia , Narinder Chawla , Craig Ison , Michael Thornton , Anita Swarnakar , Junming Yang , Thomas Richardson , Brooke Emerling , Monique Yao , Benjamin Cocks , Bharati Sanjanwala , Patricia Mason , Ameena Gandhi , Joana Li , Rajagopal Gururajan , Kimberly Gietzen , Ian Forsythe
发明人： Preeti Lal , Bridget Warren , Yuming Xu , Brendan Duggan , Cynthia Honchell , Deborah Kallick , Mariah Baughn , Y. Tang , Henry Yue , Olga Bandman , Karen Jones , Shanya Becha , Uyen Tran , Janice Au-Young , Jennifer Griffin , Yeganeh Zebarjadian , Ernestie Lee , Vicki Elliott , Kavitha Thangavelu , Jayalaxmi Ramkumar , Yan Lu , April Hafalia , Narinder Chawla , Craig Ison , Michael Thornton , Anita Swarnakar , Junming Yang , Thomas Richardson , Brooke Emerling , Monique Yao , Benjamin Cocks , Bharati Sanjanwala , Patricia Mason , Ameena Gandhi , Joana Li , Rajagopal Gururajan , Kimberly Gietzen , Ian Forsythe
IPC分类号： G01N33/50 , A61K45/00 , A61K49/00 , A61P1/00 , A61P3/00 , A61P25/00 , A61P29/00 , A61P31/12 , A61P35/00 , A61P37/06 , C07K14/47 , C07K14/705 , C07K16/28 , C07K16/46 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号： C07K14/705 , C07K14/47
摘要： The invention provides human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译： 本发明提供鉴定和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与REMAP的异常表达相关的紊乱的方法。
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公开(公告)号：US20050064543A1
公开(公告)日：2005-03-24
申请号：US10487078
申请日：2002-08-15
申请人： Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
发明人： Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
IPC分类号： G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61P9/00 , A61P25/00 , A61P29/00 , A61P37/06 , A61P43/00 , C07K1/22 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/46 , C07K19/00 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N9/16 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/11 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/00
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , C07K14/705 , C12N9/1205 , C12N9/16 , C12N9/6421
摘要： Various embodiments of the invention provide human secreted proteins(SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其它实施方案提供用于诊断，治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号：US20050142600A1
公开(公告)日：2005-06-30
申请号：US11046868
申请日：2005-02-01
申请人： Bridget Warren , Cynthia Honchell , Yan Lu , Narinder Chawla , Neil Burford , Angelo Delegeane , Ameena Gandhi , Mariah Baughn , Jennifer Griffin , Kimberly Gietzen , Dyung Lu , Craig Ison , Jayalaxmi Ramkumar , Y. Tang , Preeti Lal , Mark Borowsky , Brendan Duggan , April Hafalia , Chandra Arvizu , Kavitha Thangavelu , Monique Yao , Vicki Elliott , Li Ding , Henry Yue , Sally Lee , Anita Swarnakar , Uyen Tran , Yuming Xu
发明人： Bridget Warren , Cynthia Honchell , Yan Lu , Narinder Chawla , Neil Burford , Angelo Delegeane , Ameena Gandhi , Mariah Baughn , Jennifer Griffin , Kimberly Gietzen , Dyung Lu , Craig Ison , Jayalaxmi Ramkumar , Y. Tang , Preeti Lal , Mark Borowsky , Brendan Duggan , April Hafalia , Chandra Arvizu , Kavitha Thangavelu , Monique Yao , Vicki Elliott , Li Ding , Henry Yue , Sally Lee , Anita Swarnakar , Uyen Tran , Yuming Xu
CPC分类号： C12N9/6421 , A01K2217/05 , A61K38/00 , C07H21/04 , C12N9/64
摘要： The invention provides human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.
摘要翻译： 本发明提供了鉴定和编码PMMM的人蛋白质修饰和维持分子（PMMM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与PMMM的异常表达相关的紊乱的方法。
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公开(公告)号：US20050019763A1
公开(公告)日：2005-01-27
申请号：US10473451
申请日：2002-04-05
申请人： Ameena Gandhi , Angelo Delegeane , Anita Swarnakar , April Hafalia , Brendan Duggan , Bridget Warren , Brooke Emerling , Chandra Arvizu , Cynthia Honchell , Deborah Kallick , Dyung Lu , Ernestine Lee , Henry Yue , Ian Forsythe , Jayalaxmi Ramkumar , Jennifer Griffin , Joana Li , Kavitha Thangavelu , Mariah Baughn , Monique Yao , Madhusudan Sanjanwala , Narinder Chawla , Neil Burford , Preeti Lal , Shanya Becha , Soo Lee , Vicki Elliott , Wen Luo , Yan Lu , Yu-mei Wang
发明人： Ameena Gandhi , Angelo Delegeane , Anita Swarnakar , April Hafalia , Brendan Duggan , Bridget Warren , Brooke Emerling , Chandra Arvizu , Cynthia Honchell , Deborah Kallick , Dyung Lu , Ernestine Lee , Henry Yue , Ian Forsythe , Jayalaxmi Ramkumar , Jennifer Griffin , Joana Li , Kavitha Thangavelu , Mariah Baughn , Monique Yao , Madhusudan Sanjanwala , Narinder Chawla , Neil Burford , Preeti Lal , Shanya Becha , Soo Lee , Vicki Elliott , Wen Luo , Yan Lu , Yu-mei Wang
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/00 , A61P9/00 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/06 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , A01K67/00 , C07H21/04
CPC分类号： C12N9/6421 , A01K2217/05 , A61K38/00
摘要： The invention provides human protein modification and maintenance molecules (PMOD) and polynucleotides which identify and encode PMOD. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMOD.
摘要翻译： 本发明提供了鉴定和编码PMOD的人蛋白质修饰和维持分子（PMOD）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与PMOD异常表达相关的紊乱的方法。
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公开(公告)号：US20050191627A1
公开(公告)日：2005-09-01
申请号：US10491183
申请日：2002-09-26
申请人： Junming Yang , Aina Dyung Lu , Henry Yue , Vicki Elliott , Bridget Warren , Brendan Duggan , Ian Forsythe , Ernestine Lee , April Hafalia , Jayalaxmi Ramkumar , Narinder Chawla , Mariah Baughn , Shanya Becha , Ann Gorvad , Uyen Tran , Joana Li , Monique Yao , Craig Ison , Jennifer Griffin , Soo Lee , Hsin-Ru Chang , Brooke Emerling , Tom Tang , Preeti Lal , Amy Kable , Joseph Marquis , Xin Jiang , Alan Jackson , Yeganeh Zebarjadian , Anita Swarnakar , Amy Wilson , Pei Jin , Thomas Richardson , Umesh Bhatia , John Burrill , Sally Lee , Julie Blake , Anne Ho , Wenjin Zheng , Jin Gao
发明人： Junming Yang , Aina Dyung Lu , Henry Yue , Vicki Elliott , Bridget Warren , Brendan Duggan , Ian Forsythe , Ernestine Lee , April Hafalia , Jayalaxmi Ramkumar , Narinder Chawla , Mariah Baughn , Shanya Becha , Ann Gorvad , Uyen Tran , Joana Li , Monique Yao , Craig Ison , Jennifer Griffin , Soo Lee , Hsin-Ru Chang , Brooke Emerling , Tom Tang , Preeti Lal , Amy Kable , Joseph Marquis , Xin Jiang , Alan Jackson , Yeganeh Zebarjadian , Anita Swarnakar , Amy Wilson , Pei Jin , Thomas Richardson , Umesh Bhatia , John Burrill , Sally Lee , Julie Blake , Anne Ho , Wenjin Zheng , Jin Gao
CPC分类号： C12N9/00
摘要： Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.
摘要翻译： 本发明的各种实施方案提供了识别和编码ENZM的人类酶（ENZM）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与ENZM异常表达相关的紊乱的方法。
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公开(公告)号：US20060127894A1
公开(公告)日：2006-06-15
申请号：US10486020
申请日：2002-08-08
申请人： Yalda Azimzai , Ines Barroso , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Richard Graul , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Craig Ison , Amy Kable , Farrah Khan , Sally Lee , Soo Lee , Joana Li , Roopa Reddy , Thomas Richardson , William Sprague , Anita Swarnakar , Y. Tom Tang , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue
发明人： Yalda Azimzai , Ines Barroso , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Richard Graul , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Craig Ison , Amy Kable , Farrah Khan , Sally Lee , Soo Lee , Joana Li , Roopa Reddy , Thomas Richardson , William Sprague , Anita Swarnakar , Y. Tom Tang , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue
CPC分类号： C07K14/47 , C07K14/4747 , C07K14/4748 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/6872 , G01N2333/47
摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译： 本发明的各种实施方案提供与细胞生长，分化和死亡（CGDD）相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号：US20050107293A1
公开(公告)日：2005-05-19
申请号：US10489695
申请日：2002-09-13
申请人： William Sprague , Narinder Chawla , Bridget Warren , Y. Tom Tang , Vicki Elliott , Joseph Marquis , Joana Li , Jennifer Griffin , Kimberly Gietzen , Junming Yang , Dyung Lu , Brooke Emerling , Brendan Duggan , Thomas Richardson , Soo Lee , Jayalaxmi Ramkumar , Shanya Becha , Patricia Mason , Anita Swarnakar , Uyen Tran , Amy Kable , April Hafalia , Reena Khare
发明人： William Sprague , Narinder Chawla , Bridget Warren , Y. Tom Tang , Vicki Elliott , Joseph Marquis , Joana Li , Jennifer Griffin , Kimberly Gietzen , Junming Yang , Dyung Lu , Brooke Emerling , Brendan Duggan , Thomas Richardson , Soo Lee , Jayalaxmi Ramkumar , Shanya Becha , Patricia Mason , Anita Swarnakar , Uyen Tran , Amy Kable , April Hafalia , Reena Khare
IPC分类号： G01N33/53 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P1/00 , A61P1/18 , A61P3/00 , A61P5/00 , A61P5/24 , A61P5/38 , A61P9/00 , A61P15/00 , A61P17/00 , A61P25/00 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/06 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/566 , G01N33/577 , G01N37/00 , A61K38/45 , C07H21/04 , C12N9/12
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , C12N9/6421
摘要： Various embodiments of the invention provide human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.a.
摘要翻译： 本发明的各种实施方案提供了识别和编码PMMM的人蛋白质修饰和维持分子（PMMM）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与PMMM异常表达相关的紊乱的方法。
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