PROPHYLACTIC OR THERAPEUTIC AGENT FOR CORNEAL/CONJUNCTIVAL DISEASE
    3.
    发明申请
    PROPHYLACTIC OR THERAPEUTIC AGENT FOR CORNEAL/CONJUNCTIVAL DISEASE 审中-公开
    预防或治疗神经系统疾病

    公开(公告)号:US20100113338A1

    公开(公告)日:2010-05-06

    申请号:US11993580

    申请日:2006-06-21

    IPC分类号: A61K38/16 C07K14/00 A61P27/02

    CPC分类号: A61K38/1761 A61K9/0048

    摘要: Disclosed is a novel composition for the treatment of a corneal/conjunctival disease. A prophylactic or therapeutic agent for a corneal/conjunctival disease comprising selenoprotein P as an active ingredient, more specifically a prophylactic or therapeutic agent for a corneal/conjunctival disease such as dry eye, keratoconjunctivitis sicca, superficial punctate keratopathy, corneal erosion or corneal ulcer comprising selenoprotein P as an active ingredient, particularly a prophylactic or therapeutic agent for a corneal/conjuncrtival disease such as dry eye, keratoconjunctivitis sicca, superficial punctate keratopathy, corneal erosion or corneal ulcer accompanied by a corneal/conjunctival epithelial discorder.

    摘要翻译: 公开了用于治疗角膜/结膜疾病的新型组合物。 一种用于角膜/结膜疾病的预防或治疗剂,其包含硒蛋白P作为活性成分,更具体地,涉及用于角膜/结膜疾病如干眼症,圆锥形结膜炎丝氨酸,浅表性点状角膜病,角膜侵蚀或角膜溃疡的预防或治疗剂,其包括 硒蛋白P作为活性成分,特别是用于角膜/结膜性疾病例如干眼症,透角圆锥形结膜炎,浅表性点状角膜病变,伴随角膜/结膜上皮发生器的角膜侵蚀或角膜溃疡的预防或治疗剂。

    SUBSTRATE FOR CELL CULTURE
    6.
    发明申请
    SUBSTRATE FOR CELL CULTURE 审中-公开
    细胞培养基质

    公开(公告)号:US20080009063A1

    公开(公告)日:2008-01-10

    申请号:US11773127

    申请日:2007-07-03

    IPC分类号: C12N5/02

    摘要: An object of the present invention is to provide a cell culture substrate capable of quickly forming a cell sheet and easily removing the cell sheet after formed. The present invention relates to a cell culture substrate for forming a cell sheet by culturing cells, comprising a plurality of projections each having a top face and depressions formed between the projections, in which the depressions each have an opening whose dimensions are too small for a cell to be cultured to enter and the cell sheet is removable. The present invention further relates to a method of preparing a cell sheet using the substrate and a cell sheet prepared by the method.

    摘要翻译: 本发明的目的是提供能够快速形成细胞片并且容易地除去细胞片的细胞培养基材。 本发明涉及用于通过培养细胞形成细胞片的细胞培养基质,所述细胞培养基底包括多个突起,每个突起具有顶表面和在所述突起之间形成的凹陷,其中所述凹陷各自具有尺寸对于 要培养的细胞进入,细胞片是可移除的。 本发明还涉及使用该基材制备细胞片的方法和通过该方法制备的细胞片。

    Processes for manufacturing flexible wiring boards and the resulting flexible wiring boards
    8.
    发明授权
    Processes for manufacturing flexible wiring boards and the resulting flexible wiring boards 失效
    用于制造柔性布线板和由此产生的柔性布线板的工艺

    公开(公告)号:US06729022B2

    公开(公告)日:2004-05-04

    申请号:US10230329

    申请日:2002-08-29

    IPC分类号: H05K310

    摘要: The present invention aims to connect metal films without forming any opening in a resin film. Against a first resin film 16 formed on a first metal film 12 are pressed bumps 21 on a second metal film 11 so that the bumps 21 are embedded into the first resin film 16. Either one of the first metal film 12 or the second metal film 11 or both is (are) patterned while the bumps 21 are in contact with the first metal film 12, and the first resin film 16 is heat-treated while the top of the first resin film is partially exposed to discharge the solvent or moisture from the exposed zone and cure the first resin film 16. After curing, the bumps 21 and the first metal film 12 may be ultrasonically bonded to each other. A second resin film and a third metal film may be further layered to form a multilayer structure.

    摘要翻译: 本发明的目的是在不在树脂膜中形成任何开口的情况下连接金属膜。在第一金属膜12上形成的第一树脂膜16上,在第二金属膜11上形成按压凸块21,使得凸块21嵌入到第一金属膜11中。 在第一金属膜12或第二金属膜11中的任一个或两者均被图案化,同时凸块21与第一金属膜12接触,并且第一树脂膜16被热处理同时 第一树脂膜的顶部部分地暴露以从暴露区域排出溶剂或水分,并使第一树脂膜16固化。固化后,凸块21和第一金属膜12可以彼此超声波接合。 可以进一步层叠第二树脂膜和第三金属膜以形成多层结构。

    Board pieces, flexible wiring boards, and processes for manufacturing flexible wiring boards
    9.
    发明授权
    Board pieces, flexible wiring boards, and processes for manufacturing flexible wiring boards 有权
    板件,柔性布线板以及制造柔性布线板的工艺

    公开(公告)号:US06596947B1

    公开(公告)日:2003-07-22

    申请号:US09937590

    申请日:2002-01-18

    IPC分类号: H05K103

    摘要: A board piece 2 of the present invention comprises a non-thermoplastic resin film 11, a thermoplastic resin film 10 formed on the non-thermoplastic resin film 11 and a metal wiring 8 formed on the surface of the thermoplastic resin film 10. Metal wiring 8 is partially exposed on board piece 2 to form a contact 12. A low-melting metal coating 13 is formed on contact 12 and two board pieces 2a, 2b are pressed against each other under heating with contacts 12a, 12b thereof being in contact with each other so that thermoplastic resin films 10a, 10b soften to adhere board pieces 2a, 2b to each other and low-melting metal coatings 13a, 13b melt and then solidify to connect contacts 12a, 12b to each other. The region of metal wiring 8 not used for connection is wiring 17 connecting contacts 12 to each other and a cover film 19 can be provided on the surface thereof. Contacts 12a, 12b can also be connected by applying ultrasonic wave.

    摘要翻译: 本发明的板片2包括非热塑性树脂膜11,形成在非热塑性树脂膜11上的热塑性树脂膜10和形成在热塑性树脂膜10的表面上的金属布线8.金属布线8 被部分地暴露在板件2上以形成触点12.在触点12上形成低熔点金属涂层13,并且两个板片2a,2b在加热时被彼此挤压,其触点12a,12b与每个 使得热塑性树脂膜10a,10b软化以将板片2a,2b彼此粘合并且熔融金属涂层13a,13b熔化然后固化以将触点12a,12b彼此连接。 不用于连接的金属布线8的区域是将触点12彼此连接的布线17,并且可以在其表面上设置覆盖膜19。 触点12a,12b也可以通过施加超声波来连接。