X-Y matrix type electroluminescent display panel
    2.
    发明授权
    X-Y matrix type electroluminescent display panel 失效
    X-Y矩阵型电致发光显示面板

    公开(公告)号:US4015166A

    公开(公告)日:1977-03-29

    申请号:US683215

    申请日:1976-05-04

    CPC分类号: G09F13/22 H05B33/22

    摘要: This invention relates to an X-Y matrix type electroluminescent display panel. The panel includes a transparent insulating substrate, transparent and parallel X-electrodes of strip shape provided on said transparent insulating substrate, a D.C. electroluminescent layer provided on said transparent parallel electrodes; parallel Y-electrodes of strip shape provided on said D.C. electroluminescent layer, the direction of said Y-electrodes being perpendicular to that of said X-electrodes, said X- and Y-electrodes and said D.C. electroluminescent layer defining display elements at the intersections of said X- and Y-electrodes; and a mesh-shaped insulating layer, preferably of black color, for insulating said display elements from each other at least in the vicinity of said X-electrodes. Because of the mesh-shaped insulating layer, it becomes possible to achieve uniform "forming" of said D.C. electroluminescent layer and to improve the brightness and contrast of the resultant display panel.

    摘要翻译: 本发明涉及一种X-Y矩阵型电致发光显示面板。 所述面板包括透明绝缘基板,设置在所述透明绝缘基板上的带状的透明和平行X电极,设置在所述透明平行电极上的直流电致发光层; 设置在所述直流电致发光层上的带状平行Y电极,所述Y电极的方向垂直于所述X电极的方向,所述X电极和Y电极以及所述DC电致发光层在 所述X和Y电极; 以及优选为黑色的网状绝缘层,用于至少在所述X电极附近使所述显示元件彼此绝缘。 由于网状绝缘层,可以实现所述直流电致发光层的均匀“形成”并且提高所得显示面板的亮度和对比度。

    Method of making a manganese-activated zinc sulphide electroluminescent
powder
    3.
    发明授权
    Method of making a manganese-activated zinc sulphide electroluminescent powder 失效
    锰活化硫化锌电致发光粉的制备方法

    公开(公告)号:US3984586A

    公开(公告)日:1976-10-05

    申请号:US492327

    申请日:1974-07-26

    CPC分类号: C09K11/574

    摘要: A method of making a manganese-activated zinc sulphide electroluminescent powder for D.C. excitation which contributes to a high electroluminescent brightness, high breakdown voltage and high uniformity and fineness of luminosity of the luminous area in an electroluminescent panel. The feature of this method is to fire a mixture of raw zinc sulphide powder and a manganese compound in an atmosphere of carbon disulphide with a carrier gas.

    摘要翻译: 制造用于直流激发的锰活化硫化锌电致发光粉末的方法,其有助于电致发光面板中的发光面积的高电致发光亮度,高击穿电压和高均匀性以及亮度的光亮度。 该方法的特征在于在二硫化碳气氛中用载气喷射硫化锌粉末和锰化合物的混合物。

    Protein Detection Using Three-Dimensional Carbon Microarrays
    5.
    发明申请
    Protein Detection Using Three-Dimensional Carbon Microarrays 审中-公开
    使用三维碳微阵列的蛋白质检测

    公开(公告)号:US20140031253A1

    公开(公告)日:2014-01-30

    申请号:US13946810

    申请日:2013-07-19

    IPC分类号: G01N33/551 G01N33/74

    摘要: The potential of aptamers as ligand binding molecule have opened new avenues in the development of biosensors for proteins, such as cancer oncoproteins. Disclosed herein is a label-free detection strategy using signaling aptamer/protein binding complex for proteins, such as platelet-derived growth factor (PDGF-BB) oncoprotein. The detection mechanism is based on the release of a fluorophore (e.g., TOTO intercalating dye) from the target binding aptamer's stem structure when it captures the protein, e.g., PDGF. Amino-terminated three-dimensional carbon microarrays fabricated by pyrolyzing patterned photoresist are used as a detection platform. The sensor showed near linear relationship between the relative fluorescence difference and protein concentration even in the sub-nanomolar range with an excellent detection limit of 5 pmol. This detection strategy is promising in a wide range of applications in the detection of cancer biomarkers and other proteins.

    摘要翻译: 适体作为配体结合分子的潜力为开发蛋白质生物传感器(如癌症癌蛋白)开辟了新的途径。 本文公开了使用信号转导蛋白/蛋白质结合复合物(例如血小板衍生生长因子(PDGF-BB)癌蛋白)的无标记检测策略。 检测机制基于当其捕获蛋白质例如PDGF时从靶结合适体的茎结构释放荧光团(例如,TOTO嵌入染料)。 使用通过热解图案化光致抗蚀剂制造的氨基封端的三维碳微阵列用作检测平台。 传感器即使在亚纳摩尔范围内也显示相对荧光差异和蛋白质浓度之间的近似线性关系,检出限为5 pmol。 该检测策略在肿瘤生物标志物和其他蛋白质的检测中的应用范围广泛。

    Dna Sensor and Measuring Method Using the Same
    6.
    发明申请
    Dna Sensor and Measuring Method Using the Same 有权
    Dna传感器和使用它的测量方法

    公开(公告)号:US20080032294A1

    公开(公告)日:2008-02-07

    申请号:US11661033

    申请日:2005-08-04

    申请人: Hiroshi Kawarada

    发明人: Hiroshi Kawarada

    IPC分类号: C12Q1/68 C12M1/00

    摘要: A DNA sensor is provided which is capable of identifying unknown DNA with enhanced detection sensitivity of the hybridization. A p-channel field-effect transistor having an electrolyte solution gate 8 and having as a p-channel 5 a diamond surface 2 which contains a mixture of at least a hydrogen-terminated surface and a surface terminated with an amino group or a molecule with an amino group is configured along with a probe DNA 11 constituted of a single-stranded DNA with known nucleotide sequence which is directly immobilized by a linker to the diamond surface 2 and with a target DNA constituted of an unknown single-stranded DNA which is dropped on the diamond surface 2. When the target DNA is in complementary relationship to the probe DNA 11, negative electric charge of the phosphate group of a double-stranded DNA produced by the hybridization of the probe DNA 11 with the target DNA both constituted of a single-stranded DNA is doubled, thereby resulting in increase of the hole density in the p-channel and shift of the threshold voltage of the p-channel field effect transistor toward positive direction. By detecting this shift of the threshold voltage toward positive direction, an identification can be made on whether or not the target DNA is in complementary relationship to the probe DNA 11.

    摘要翻译: 提供DNA传感器,其能够鉴定具有增强的杂交检测灵敏度的未知DNA。 具有电解液栅极8并且具有作为p沟道5的金刚石表面2的p沟道场效应晶体管,金刚石表面2包含至少氢封端的表面和用氨基或分子封端的表面的混合物, 将氨基与由具有已知核苷酸序列的单链DNA构成的探针DNA一起构建,所述核酸序列通过接头直接固定在金刚石表面2上,并与由未知的单链DNA构成的靶DNA被滴落 当靶DNA与探针DNA11互补关系时,通过探针DNA 11与目标DNA的杂交产生的双链DNA的磷酸基团的负电荷都由 单链DNA加倍,从而导致p沟道中的空穴密度增加,并且p沟道场效应晶体管的阈值电压向正方向移动。 通过检测阈值电压向正方向的偏移,可以确定目标DNA是否与探针DNA11具有互补关系。

    DNA sensor
    9.
    发明授权
    DNA sensor 有权
    DNA传感器

    公开(公告)号:US07851205B2

    公开(公告)日:2010-12-14

    申请号:US11661033

    申请日:2005-08-04

    申请人: Hiroshi Kawarada

    发明人: Hiroshi Kawarada

    摘要: A DNA sensor including a p-channel field-effect transistor having as a gate an electrolyte solution and having as a channel a diamond surface which contains a mixture of at least a hydrogen-terminated surface and a surface terminated by an amino group or a molecule with an amino group as an amino termination; a probe DNA constituted of a single-stranded DNA with known nucleotide sequence which is directly immobilized by a linker to the amino termination of the diamond surface; and a target DNA constituted of an unknown single-stranded DNA which is dropped on said diamond surface, wherein the hybridization of the target and probe is ascertained by detecting a shift of the threshold voltage of said p-channel field effect transistor toward positive direction which is due to increase in hole density of the p-channel resulting from doubling the negative electric charge of the phosphate groups upon hybridization.

    摘要翻译: 一种DNA传感器,包括具有作为电解液的栅极的p沟道场效应晶体管,并且具有作为沟道的金刚石表面,所述金刚石表面含有至少氢封端的表面和由氨基或分子封端的表面的混合物 具有氨基作为氨基末端; 由具有已知核苷酸序列的单链DNA构建的探针DNA,其通过接头直接固定在金刚石表面的氨基末端; 以及由所述金刚石表面上的未知单链DNA构成的靶DNA,其中通过检测所述p沟道场效应晶体管的阈值电压向正方向的偏移来确定靶和探针的杂交, 是由于在杂交时使磷酸基团的负电荷加倍导致的p通道的空穴密度增加。

    Field-effect transistor
    10.
    发明授权
    Field-effect transistor 有权
    场效应晶体管

    公开(公告)号:US06833059B2

    公开(公告)日:2004-12-21

    申请号:US09959905

    申请日:2001-11-13

    申请人: Hiroshi Kawarada

    发明人: Hiroshi Kawarada

    IPC分类号: G01N27327

    摘要: An object is to provide a field effect transistor which uses a liquid electrolyte as a gate and which operates stably in the liquid electrolyte. A field effect transistor includes a channel (2) formed of a portion of a hydrogen-terminated surface of a diamond, the portion being exposed to the outside between a gate electrode (3) and a drain electrode (6); and a gate formed of a liquid electrolyte (4) in contact with the exposed portion of the hydrogen-terminated surface of the diamond.

    摘要翻译: 目的是提供一种使用液体电解质作为栅极并在液体电解质中稳定地工作的场效应晶体管。场效应晶体管包括由金刚石的氢终止表面的一部分形成的沟道(2) 所述部分在栅电极(3)和漏电极(6)之间暴露于外部; 以及由与金刚石的氢终止表面的暴露部分接触的液体电解质(4)形成的门。