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    Method for producing target substance by fermentation
    4.
    发明授权
    Method for producing target substance by fermentation 有权
    通过发酵生产目标物质的方法

    公开(公告)号：US08497087B2

    公开(公告)日：2013-07-30

    申请号：US11275900

    申请日：2006-02-02

    申请人： Nobuharu Tsujimoto ,  Tomoko Suzuki ,  Hisao Ito

    发明人： Nobuharu Tsujimoto ,  Tomoko Suzuki ,  Hisao Ito

    IPC分类号： C12P1/00 ,  C12P13/04 ,  C12P13/22 ,  C12P13/08 ,  C12N1/21

    CPC分类号： C07K14/245 ,  C12P13/04 ,  C12P13/08 ,  C12P13/222

    摘要： A method for producing a target substance by utilizing a microorganism by culturing the microorganism in a medium to produce and accumulate the target substance in the medium and collecting the target substance from the culture is described. The microorganism is a mutant recombinant strain in which maltose assimilation is controlled by reducing or eliminating the interaction between IIAGlc protein of the glucose PTS and a protein involved in non-PTS uptake of maltose.

    摘要翻译： 描述了通过在培养基中培养微生物来生产和积累目标物质并从培养物中收集目标物质的微生物生产目标物质的方法。 该微生物是通过减少或消除葡萄糖PTS的IIAGlc蛋白与参与非PTS摄取麦芽糖的蛋白质之间的相互作用来控制麦芽糖同化的突变重组菌株。

    Bacteria containing aspartate-semialdehyde dehydrogenase, phosphoenolpyruvate carboxylase, and transhydrogenase to produce L-lysine in escherichia, and methods of using same
    5.
    发明授权
    Bacteria containing aspartate-semialdehyde dehydrogenase, phosphoenolpyruvate carboxylase, and transhydrogenase to produce L-lysine in escherichia, and methods of using same 有权
    含有天冬氨酸 - 半醛脱氢酶，磷酸烯醇丙酮酸羧化酶和转氢酶在埃希氏菌中产生L-赖氨酸的细菌及其使用方法

    公开(公告)号：US07723081B1

    公开(公告)日：2010-05-25

    申请号：US10149450

    申请日：2000-01-21

    申请人： Kazuo Nakanishi ,  Yoshimi Kikuchi ,  Junichiro Kojima ,  Tomoko Suzuki ,  Yasushi Nishimura ,  Hiroyuki Kojima

    发明人： Kazuo Nakanishi ,  Yoshimi Kikuchi ,  Junichiro Kojima ,  Tomoko Suzuki ,  Yasushi Nishimura ,  Hiroyuki Kojima

    IPC分类号： C12P13/08

    CPC分类号： C12P13/08 ,  C12N15/52

    摘要： An Escherichia bacterium (1) which harbors dihydrodipicolinate synthase of which feedback inhibition by L-lysine is desensitized and aspartokinase of which feedback inhibition by L-lysine is desensitized, (2) in which intracellular activity of dihydrodipicolinate reductase is enhanced, and (3) in which a diaminopimelate dehydrogenase gene is introduced or intracellular activities of tetrahydrodipicolinate succinylase and succinyl diaminopimelate deacylase are enhanced, wherein intracellular activity of aspartate-semialdehyde dehydrogenase or phosphoenolpyruvate carboxylase is enhanced, is cultured in a suitable medium to produce and accumulate L-lysine in culture, and the L-lysine is collected from the culture.

    摘要翻译： 具有L-赖氨酸的反馈抑制脱敏的二氢吡啶并吡啶合酶的大肠杆菌细菌（1），L-赖氨酸的反馈抑制的天冬氨酸脱敏，（2）二氢吡啶二羧酸还原酶的细胞内活性增强，（3） 其中引入二氨基庚二酸脱氢酶基因或增加四氢二吡啶甲酰基琥珀酰基酶和琥珀酰二氨基庚二酸脱酰基酶的细胞内活性，其中天冬氨酸半醛脱氢酶或磷酸烯醇丙酮酸羧化酶的细胞内活性增强，在合适的培养基中培养以在培养物中产生和积累L-赖氨酸 ，并从培养物中收集L-赖氨酸。

    Zero thermal expansion material and practical component parts making use of the same
    8.
    发明授权
    Zero thermal expansion material and practical component parts making use of the same 有权
    零热膨胀材料和实用组件使用相同

    公开(公告)号：US06844283B2

    公开(公告)日：2005-01-18

    申请号：US10837718

    申请日：2004-05-04

    申请人： Tomoko Suzuki ,  Atsushi Omote ,  Jun Kuwata

    发明人： Tomoko Suzuki ,  Atsushi Omote ,  Jun Kuwata

    IPC分类号： C04B35/00 ,  C01G39/00 ,  C01G41/00 ,  C01G49/00 ,  C04B35/053 ,  C04B35/488 ,  C04B35/495 ,  H01L23/15 ,  H05K1/03 ,  C04B35/486

    CPC分类号： C04B35/053 ,  C01G39/00 ,  C01G39/006 ,  C01G41/006 ,  C01G49/00 ,  C01P2002/72 ,  C01P2006/10 ,  C01P2006/32 ,  C04B35/488 ,  C04B35/495 ,  H01L23/15 ,  H01L2924/0002 ,  H05K1/0306 ,  H01L2924/00

    摘要： Using as a negative thermal expansion material a double oxide containing at least partly a compound represented by the chemical formula: RQ,O, (wherein R is Zr, Hf or a tetravalent metallic element represented by a mixture system of these, and Q is a hexavalent metallic element selected from W and Mo), and using as a positive thermal expansion material a material containing at least partly a compound represented by the chemical formula: MQX, (wherein M is Mg, Ca, Sr, Ba, Ra or a divalent metallic element represented by a mixture system of any of these, Q is a hexavalent metallic element selected from W and Mo, and X is an element selected from O and S), these are mixed preferably in a weight ratio of 1:1 and are synthesized to obtain a material whose coefficient of thermal expansion is substantially zero over a wide temperature range, i.e., a zero thermal expansion material. Using this zero thermal expansion material, high-precision and high-performance practical component parts can be obtained.

    摘要翻译： 使用至少部分由化学式RQ2O8表示的化合物（其中R是Zr，Hf或由它们的混合体系表示的四价金属元素）的双氧化物作为负热膨胀材料，Q是六价金属元素 选自W和Mo），并且使用至少部分由化学式MQX4表示的化合物（其中M为Mg，Ca，Sr，Ba，Ra或由下式表示的二价金属元素作为正热膨胀材料） 任何这些的混合体系，Q是选自W和Mo的六价金属元素，X是选自O和S的元素），优选以1:1的重量比混合，得到 热膨胀系数在宽温度范围内基本为零的材料，即零热膨胀材料。 使用这种零热膨胀材料，可以获得高精度和高性能的实用部件。