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公开(公告)号：US20100076536A1
公开(公告)日：2010-03-25
申请号：US12442133
申请日：2007-09-18
CPC分类号： A61N1/0529 , A61B5/04001 , A61L31/148 , A61N1/0531 , A61N1/0534 , A61N1/0536 , A61N1/0539 , A61N1/0558 , A61N1/36082
摘要： The invention provides an implantable multi-electrode device (300) and related methods and apparatuses. In one embodiment, the invention includes an implantable device (300) comprising: an assembly block (320); and a plurality of leads (340 . . . 348) radiating from the assembly block (320), each of the plurality of leads (340 . . . 348) containing at least one electrode (342A), such that the electrodes are distributed within a three-dimensional space, wherein the assembly block (320) includes a barb (350) for anchoring the assembly block (320) within implanted tissue.
摘要翻译： 本发明提供一种可植入式多电极装置（300）及其相关方法和装置。 在一个实施例中，本发明包括可植入装置（300），包括：组装块（320）; 以及从所述组装块（320）辐射的多个引线（340 ... 348），所述多个引线（340 ... 348）中的每一个包含至少一个电极（342A），使得所述电极分布在 三维空间，其中组装块（320）包括用于将组装块（320）固定在植入的组织内的倒钩（350）。
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公开(公告)号：US20100041988A1
公开(公告)日：2010-02-18
申请号：US12442197
申请日：2007-09-19
CPC分类号： A61B17/2202 , A61B17/2256 , A61B2017/00106
摘要： A method is disclosed using a feedback loop for focused ultrasound application. The method includes the steps of determining a location of a target side within a body using ultrasound waves, applying focused ultrasound waves to the target site, determining a new location of the target site using further ultrasound waves, and adjusting the focused ultrasound waves in response to the new location of the target site.
摘要翻译： 公开了一种使用聚焦超声应用的反馈回路的方法。 该方法包括以下步骤：使用超声波确定身体内目标侧的位置，向目标位置施加聚焦超声波，使用另外的超声波确定目标位置的新位置，以及响应于调整聚焦超声波 到目标网站的新位置。
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公开(公告)号：US20100066348A1
公开(公告)日：2010-03-18
申请号：US12595090
申请日：2008-04-05
CPC分类号： G01N33/48721 , C12Q1/6869 , G01N27/414 , C12Q2565/631
摘要： A detector device comprises a substrate (50), a source region (S) and a drain region (D), and a channel region (65) between the source and drain regions. A nanopore (54) passes through the channel region, and connects fluid chambers (56,58) on opposite sides of the substrate. A voltage bias is provided between the fluid chambers, the source and drain regions and a charge flow between the source and drain regions is sensed. The device uses a nanopore for the confinement of a sample under test (for example nucleotides) close to a sensor. The size of the sensor can be made similar to the spacing of adjacent nucleotides in a DNA strand. In this way, the disadvantages of PCR based techniques for DNA sequencing are avoided, and single nucleotide resolution can be attained.
摘要翻译： 检测器装置包括衬底（50），源极区（S）和漏极区（D）以及在源极和漏极区之间的沟道区（65）。 纳米孔（54）穿过沟道区域，并且连接在衬底的相对侧上的流体室（56,58）。 在流体室，源极和漏极区之间提供电压偏置，并且感测源区和漏区之间的电荷流。 该装置使用纳米孔来限制待测样品（例如核苷酸）靠近传感器。 可以使传感器的尺寸与DNA链中相邻核苷酸的间隔相似。 以这种方式，避免了基于PCR的DNA测序技术的缺点，可以实现单核苷酸分辨率。
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公开(公告)号：US08798737B2
公开(公告)日：2014-08-05
申请号：US12442133
申请日：2007-09-18
IPC分类号： A61N1/00
CPC分类号： A61N1/0529 , A61B5/04001 , A61L31/148 , A61N1/0531 , A61N1/0534 , A61N1/0536 , A61N1/0539 , A61N1/0558 , A61N1/36082
摘要： The invention provides an implantable multi-electrode device (300) and related methods and apparatuses. In one embodiment, the invention includes an implantable device (300) comprising: an assembly block (320); and a plurality of leads (340 . . . 348) radiating from the assembly block (320), each of the plurality of leads (340 . . . 348) containing at least one electrode (342A), such that the electrodes are distributed within a three-dimensional space, wherein the assembly block (320) includes a barb (350) for anchoring the assembly block (320) within implanted tissue.
摘要翻译： 本发明提供一种可植入式多电极装置（300）及其相关方法和装置。 在一个实施例中，本发明包括可植入装置（300），包括：组装块（320）; 以及从所述组装块（320）辐射的多个引线（340 ... 348），所述多个引线（340 ... 348）中的每一个包含至少一个电极（342A），使得所述电极分布在 三维空间，其中组装块（320）包括用于将组装块（320）固定在植入的组织内的倒钩（350）。
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公开(公告)号：US09034637B2
公开(公告)日：2015-05-19
申请号：US12595090
申请日：2008-04-05
IPC分类号： C12M1/34 , C12M1/00 , C12M3/00 , G01R31/26 , H01L21/66 , G01N33/487 , C12Q1/68 , G01N27/414
CPC分类号： G01N33/48721 , C12Q1/6869 , G01N27/414 , C12Q2565/631
摘要： A detector device comprises a substrate (50), a source region (S) and a drain region (D), and a channel region (65) between the source and drain regions. A nanopore (54) passes through the channel region, and connects fluid chambers (56,58) on opposite sides of the substrate. A voltage bias is provided between the fluid chambers, the source and drain regions and a charge flow between the source and drain regions is sensed. The device uses a nanopore for the confinement of a sample under test (for example nucleotides) close to a sensor. The size of the sensor can be made similar to the spacing of adjacent nucleotides in a DNA strand. In this way, the disadvantages of PCR based techniques for DNA sequencing are avoided, and single nucleotide resolution can be attained.
摘要翻译： 检测器装置包括衬底（50），源极区（S）和漏极区（D）以及在源极和漏极区之间的沟道区（65）。 纳米孔（54）穿过沟道区域，并且连接在衬底的相对侧上的流体室（56,58）。 在流体室，源极和漏极区之间提供电压偏置，并且感测源区和漏区之间的电荷流。 该装置使用纳米孔来限制待测样品（例如核苷酸）靠近传感器。 可以使传感器的尺寸与DNA链中相邻核苷酸的间隔相似。 以这种方式，避免了基于PCR的DNA测序技术的缺点，可以实现单核苷酸分辨率。
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公开(公告)号：US09679857B2
公开(公告)日：2017-06-13
申请号：US15266809
申请日：2016-09-15
IPC分类号： H01L23/52 , B81C1/00 , B81B7/02 , G01P15/06 , H01L23/00 , B81C99/00 , B81B7/00 , H01L21/768 , H01L23/522 , H01L23/525 , H01L23/528 , G01P15/08
CPC分类号： H01L23/564 , B81B7/0006 , B81B2201/0235 , B81B2203/0315 , B81B2207/015 , B81C1/00246 , B81C99/005 , B81C2201/013 , B81C2203/0136 , B81C2203/0714 , G01P15/06 , G01P15/0802 , G01P2015/0862 , G01P2015/0877 , H01L21/768 , H01L23/5226 , H01L23/5256 , H01L23/528
摘要： Disclosed is a semiconductor device comprising a stack of patterned metal layers separated by dielectric layers, the stack comprising a first conductive support structure and a second conductive support structure and a cavity in which an inertial mass element comprising at least one metal portion is conductively coupled to the first support structure and the second support structure by respective conductive connection portions, at least one of said conductive connection portions being designed to break upon the inertial mass element being exposed to an acceleration force exceeding a threshold defined by the dimensions of the conductive connection portions. A method of manufacturing such a semiconductor device is also disclosed.
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公开(公告)号：US20170005045A1
公开(公告)日：2017-01-05
申请号：US15266809
申请日：2016-09-15
IPC分类号： H01L23/00 , H01L23/528 , G01P15/06 , B81B7/00 , H01L23/525 , H01L21/768 , H01L23/522 , B81C1/00
CPC分类号： H01L23/564 , B81B7/0006 , B81B2201/0235 , B81B2203/0315 , B81B2207/015 , B81C1/00246 , B81C99/005 , B81C2201/013 , B81C2203/0136 , B81C2203/0714 , G01P15/06 , G01P15/0802 , G01P2015/0862 , G01P2015/0877 , H01L21/768 , H01L23/5226 , H01L23/5256 , H01L23/528
摘要： Disclosed is a semiconductor device comprising a stack of patterned metal layers separated by dielectric layers, the stack comprising a first conductive support structure and a second conductive support structure and a cavity in which an inertial mass element comprising at least one metal portion is conductively coupled to the first support structure and the second support structure by respective conductive connection portions, at least one of said conductive connection portions being designed to break upon the inertial mass element being exposed to an acceleration force exceeding a threshold defined by the dimensions of the conductive connection portions. A method of manufacturing such a semiconductor device is also disclosed.
摘要翻译： 公开了一种半导体器件，其包括由电介质层分隔的图案化金属层的堆叠，所述堆叠包括第一导电支撑结构和第二导电支撑结构以及空腔，其中包括至少一个金属部分的惯性质量元件导电耦合到 所述第一支撑结构和所述第二支撑结构由相应的导电连接部分组成，所述导电连接部分中的至少一个设计成使所述惯性质量元件断裂，所述加速力超过由所述导电连接部分的尺寸限定的阈值 。 还公开了制造这种半导体器件的方法。
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公开(公告)号：US08925371B2
公开(公告)日：2015-01-06
申请号：US13382726
申请日：2010-07-16
CPC分类号： G01N27/223 , G01N33/004
摘要： A sensor (2) for sensing a first substance and a second substance, the sensor comprising first (3) and second (5) sensor components each comprising a first material (20), the first material being sensitive to both the first substance and the second substance, the sensor further comprising a barrier (18) for preventing the second substance from passing into the second sensor component (5).
摘要翻译： 一种用于感测第一物质和第二物质的传感器（2），所述传感器包括第一（3）和第二（5）个传感器部件，每个传感器部件包括第一材料（20），所述第一材料对第一物质和 第二物质，传感器还包括用于防止第二物质进入第二传感器部件（5）的阻挡层（18）。
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公开(公告)号：US08864968B2
公开(公告)日：2014-10-21
申请号：US12858353
申请日：2010-08-17
IPC分类号： G01N27/333 , G01N27/416 , G01N27/414
CPC分类号： G01N27/4167 , G01N27/333 , G01N27/414 , Y10T29/4913
摘要： An electrochemical sensor device including a sensor chip having an integrated electrochemical sensor element; and a substrate having a first surface on which the sensor chip is mounted, the substrate comprising a reference electrode structure for the integrated electrochemical sensor element, the reference electrode structure connected to the sensor chip via an electrical connection on the first surface of the substrate.
摘要翻译： 一种电化学传感器装置，包括具有集成的电化学传感器元件的传感器芯片; 以及基板，其具有安装有传感器芯片的第一表面，所述基板包括用于所述一体化电化学传感器元件的参考电极结构，所述参考电极结构通过所述基板的第一表面上的电连接连接到所述传感器芯片。
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10.发明申请公开(公告)号：US20130032903A1
公开(公告)日：2013-02-07
申请号：US13556926
申请日：2012-07-24
申请人： Matthias Merz , Aurelie Humbert , Roel Daamen , David Tio Castro
发明人： Matthias Merz , Aurelie Humbert , Roel Daamen , David Tio Castro
CPC分类号： G01N27/128 , G01N25/18 , G01N27/121 , G01N27/125 , G01N27/22 , G01N33/004 , G01N33/18 , G01N33/1826 , H01L2224/73265 , H01L2224/92247 , H01L2924/1461 , H01L2924/00
摘要： Disclosed is an integrated circuit comprising a substrate (10) carrying a plurality of circuit elements; a metallization stack (12, 14, 16) interconnecting said circuit elements, said metallization stack comprising a patterned upper metallization layer comprising a first metal portion (20) and a second metal portion (21); a passivation stack (24, 26, 28) covering the metallization stack; a gas sensor including a sensing material portion (32, 74) on the passivation stack; a first conductive portion (38) extending through the passivation stack connecting a first region of the sensing material portion to the first metal portion; and a second conductive portion (40) extending through the passivation stack connecting a second region of the sensing material portion to the second metal portion. A method of manufacturing such an IC is also disclosed.
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