公开(公告)号：US20060113537A1

公开(公告)日：2006-06-01

申请号：US11326967

申请日：2006-01-05

申请人： Peter Krulevitch ,  Mariam Maghribi ,  William Benett ,  Julie Hamilton ,  Klint Rose ,  James Davidson ,  Mark Strauch

发明人： Peter Krulevitch ,  Mariam Maghribi ,  William Benett ,  Julie Hamilton ,  Klint Rose ,  James Davidson ,  Mark Strauch

IPC分类号： H01L31/0376

CPC分类号： H01L25/165 ,  B81C1/0023 ,  H01L21/6835 ,  H01L31/048 ,  H01L31/0543 ,  H01L2221/68345 ,  H01L2924/0002 ,  H01L2924/09701 ,  H01L2924/19041 ,  H01L2924/19105 ,  Y02E10/52 ,  H01L2924/00

摘要： A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.

公开(公告)号：US20060052656A1

公开(公告)日：2006-03-09

申请号：US10938816

申请日：2004-09-09

申请人： Mariam Maghribi ,  Peter Krulevitch ,  James Davidson ,  Julie Hamilton

发明人： Mariam Maghribi ,  Peter Krulevitch ,  James Davidson ,  Julie Hamilton

IPC分类号： A61N2/00

CPC分类号： A61N1/0541 ,  A61N1/0543

摘要： A system for movement in a body and performing a function on the body. The system comprises a polymer body portion, an electronic unit carried by the polymer body portion, a circuit in the polymer body portion operatively connected to the electronic unit, pieces in the polymer body portion, and a system for controlling movement of the polymer body portion utilizing magnetic forces controlling movement of the pieces. The system utilizes magnetic guidance to control movement of a polymer body portion.

摘要翻译： 用于身体运动并在身体上执行功能的系统。 该系统包括聚合物主体部分，由聚合物主体部分承载的电子单元，可操作地连接到电子单元的聚合物主体部分中的电路，聚合物主体部分中的片，以及用于控制聚合物主体部分的运动的系统 利用磁力控制片的运动。 该系统利用磁引导来控制聚合物主体部分的运动。

公开(公告)号：US20050136639A1

公开(公告)日：2005-06-23

申请号：US10742112

申请日：2003-12-18

申请人： J. Davidson ,  Peter Krulevitch ,  Mariam Maghribi ,  Julie Hamilton ,  William Benett ,  Armando Tovar

发明人： J. Davidson ,  Peter Krulevitch ,  Mariam Maghribi ,  Julie Hamilton ,  William Benett ,  Armando Tovar

IPC分类号： H01L21/44 ,  H01L21/768 ,  H05K3/40

CPC分类号： H01L21/76838 ,  H05K3/4053 ,  H05K2203/0195 ,  H05K2203/0338 ,  Y10T29/49155

摘要： A system for metalization of an integrated microsystem. The system comprises providing a substrate and applying a conductive material to the substrate by taking up small aliquots of conductive material and releasing the conductive material onto the substrate to produce a circuit component.

摘要翻译： 一个集成微系统的金属化系统。 该系统包括提供衬底并且通过吸收导电材料的小等分试样并将导电材料释放到衬底上以产生电路部件而将导电材料施加到衬底。

公开(公告)号：US07601286B2

公开(公告)日：2009-10-13

申请号：US10107933

申请日：2002-03-26

申请人： William Benett ,  Peter Krulevitch ,  Mariam Maghribi ,  Julie Hamilton ,  Klint Rose ,  Amy W. Wang

发明人： William Benett ,  Peter Krulevitch ,  Mariam Maghribi ,  Julie Hamilton ,  Klint Rose ,  Amy W. Wang

IPC分类号： B29C33/76

CPC分类号： B29C39/10 ,  B29C33/3842 ,  B29C39/34 ,  B29K2083/00 ,  B29K2083/005 ,  B29L2031/24 ,  B29L2031/756

摘要： A method of forming a polymer-based microfluidic system platform using network building blocks selected from a set of interconnectable network building blocks, such as wire, pins, blocks, and interconnects. The selected building blocks are interconnectably assembled and fixedly positioned in precise positions in a mold cavity of a mold frame to construct a three-dimensional model construction of a microfluidic flow path network preferably having meso-scale dimensions. A hardenable liquid, such as poly (dimethylsiloxane) is then introduced into the mold cavity and hardened to form a platform structure as well as to mold the microfluidic flow path network having channels, reservoirs and ports. Pre-fabricated elbows, T's and other joints are used to interconnect various building block elements together. After hardening the liquid the building blocks are removed from the platform structure to make available the channels, cavities and ports within the platform structure. Microdevices may be embedded within the cast polymer-based platform, or bonded to the platform structure subsequent to molding, to create an integrated microfluidic system. In this manner, the new microfluidic platform is versatile and capable of quickly generating prototype systems, and could easily be adapted to a manufacturing setting.

公开(公告)号：US20060029731A1

公开(公告)日：2006-02-09

申请号：US11243302

申请日：2005-10-03

申请人： James Davidson ,  Peter Krulevitch ,  Mariam Maghribi ,  William Benett ,  Julie Hamilton ,  Armando Tovar

发明人： James Davidson ,  Peter Krulevitch ,  Mariam Maghribi ,  William Benett ,  Julie Hamilton ,  Armando Tovar

IPC分类号： B05D3/12 ,  B05D5/00 ,  B05D1/02 ,  B05D3/02

CPC分类号： H01L23/145 ,  H01L23/5387 ,  H01L2924/0002 ,  H01L2924/1433 ,  H05K1/0272 ,  H05K1/0283 ,  H05K1/032 ,  H05K1/0393 ,  H05K1/095 ,  H05K3/101 ,  H05K3/12 ,  H05K3/1216 ,  H05K3/1258 ,  H05K3/1275 ,  H05K2201/0162 ,  H05K2203/0108 ,  H05K2203/0126 ,  H05K2203/082 ,  Y10S428/901 ,  Y10T428/24917 ,  H01L2924/00

摘要： A system of metalization in an integrated polymer microsystem. A flexible polymer substrate is provided and conductive ink is applied to the substrate. In one embodiment the flexible polymer substrate is silicone. In another embodiment the flexible polymer substrate comprises poly(dimethylsiloxane).

公开(公告)号：US06921603B2

公开(公告)日：2005-07-26

申请号：US10131846

申请日：2002-04-24

申请人： Jeffrey D. Morse ,  Klint A Rose ,  Mariam Maghribi ,  William Benett ,  Peter Krulevitch ,  Julie Hamilton ,  Robert T. Graff ,  Alan Jankowski

发明人： Jeffrey D. Morse ,  Klint A Rose ,  Mariam Maghribi ,  William Benett ,  Peter Krulevitch ,  Julie Hamilton ,  Robert T. Graff ,  Alan Jankowski

IPC分类号： B01D65/00 ,  B01D67/00 ,  B01D71/70 ,  H01M4/86 ,  H01M8/00 ,  H01M8/02 ,  H01M8/04 ,  H01M8/10

CPC分类号： B01D67/0034 ,  B01D65/003 ,  B01D67/0032 ,  B01D71/70 ,  B01D2323/24 ,  B01D2325/028 ,  B01D2325/08 ,  H01M8/0239 ,  H01M8/0245 ,  H01M8/04037 ,  H01M8/04089 ,  H01M8/1007 ,  H01M8/1097 ,  Y10T29/49114

摘要： Described herein is a process for fabricating microfluidic systems with embedded components in which micron-scale features are molded into the polymeric material polydimethylsiloxane (PDMS). Micromachining is used to create a mold master and the liquid precursors for PDMS are poured over the mold and allowed to cure. The PDMS is then removed form the mold and bonded to another material such as PDMS, glass, or silicon after a simple surface preparation step to form sealed microchannels.

摘要翻译： 本文描述了一种用于制造具有嵌入组件的微流体系统的方法，其中将微米级特征模制成聚合物材料聚二甲基硅氧烷（PDMS）。 微加工用于制造模具主体，将PDMS的液体前体倒在模具上并使其固化。 然后在简单的表面制备步骤之后，从模具中除去PDMS并结合到另一种材料如PDMS，玻璃或硅，以形成密封的微通道。

公开(公告)号：US20070142878A1

公开(公告)日：2007-06-21

申请号：US11545190

申请日：2006-10-10

申请人： Peter Krulevitch ,  Dennis Polla ,  Mariam Maghribi ,  Julie Hamilton ,  Mark Humayun ,  James Weiland

发明人： Peter Krulevitch ,  Dennis Polla ,  Mariam Maghribi ,  Julie Hamilton ,  Mark Humayun ,  James Weiland

IPC分类号： A61N1/18

CPC分类号： A61N1/0543 ,  H05K1/118 ,  H05K3/205 ,  H05K3/4007 ,  H05K2201/0162 ,  H05K2201/09481 ,  H05K2203/0733 ,  Y10S623/90 ,  Y10S623/901 ,  Y10S623/905 ,  Y10S623/926 ,  Y10T29/49128 ,  Y10T29/4913 ,  Y10T29/49139 ,  Y10T29/49147 ,  Y10T29/49155 ,  Y10T29/49165 ,  Y10T29/49169 ,  Y10T29/49224

摘要： An image is captured or otherwise converted into a signal in an artificial vision system. The signal is transmitted to the retina utilizing an implant. The implant consists of a polymer substrate made of a compliant material such as poly(dimethylsiloxane) or PDMS. The polymer substrate is conformable to the shape of the retina. Electrodes and conductive leads are embedded in the polymer substrate. The conductive leads and the electrodes transmit the signal representing the image to the cells in the retina. The signal representing the image stimulates cells in the retina.

摘要翻译： 图像被捕获或以其他方式转换成人造视觉系统中的信号。 使用植入物将信号传输到视网膜。 植入物由由诸如聚（二甲基硅氧烷）或PDMS的柔顺材料制成的聚合物基材组成。 聚合物基材与视网膜的形状一致。 电极和导电引线嵌入在聚合物基底中。 导电引线和电极将表示图像的信号传输到视网膜中的细胞。 表示图像的信号刺激视网膜中的细胞。

公开(公告)号：US20060074460A1

公开(公告)日：2006-04-06

申请号：US10825782

申请日：2004-04-16

申请人： Mariam Maghribi ,  Peter Krulevitch ,  James Davidson ,  Julie Hamilton

发明人： Mariam Maghribi ,  Peter Krulevitch ,  James Davidson ,  Julie Hamilton

IPC分类号： A61N1/08 ,  A61N1/04

CPC分类号： A61N1/0543 ,  A61N1/0534 ,  A61N1/0541

摘要： A high density polymer-based integrated electrode apparatus that comprises a central electrode body and a multiplicity of arms extending from the electrode body. The central electrode body and the multiplicity of arms are comprised of a silicone material with metal features in said silicone material that comprise electronic circuits.

摘要翻译： 一种高密度聚合物基集成电极装置，包括中心电极体和从电极体延伸的多个臂。 中心电极体和多个臂由具有包括电子电路的所述硅氧烷材料中的金属特征的硅氧烷材料构成。

公开(公告)号：US20050273075A1

公开(公告)日：2005-12-08

申请号：US10863043

申请日：2004-06-08

申请人： Peter Krulevitch ,  Mariam Maghribi

发明人： Peter Krulevitch ,  Mariam Maghribi

IPC分类号： A61F2/958 ,  A61M25/00 ,  A61M31/00 ,  A61M37/00

CPC分类号： A61M37/0015 ,  A61M25/10 ,  A61M2025/0093 ,  A61M2025/105 ,  A61M2025/1086 ,  A61M2037/0023 ,  A61M2037/0046

摘要： A method for delivering a therapeutic agent into tissue includes providing a device for delivering a therapeutic agent into tissue. The device has an elongated body; a first balloon in the body expandable from a collapsed position to an expanded position; a second balloon in the body expandable from a collapsed position to an expanded position. The second balloon has a plurality of apertures therein; and a therapeutic agent is located in the second balloon. A plurality of microprojections are located on a surface of the second balloon for penetrating tissue. Upon expansion of the first balloon from the collapsed position to the expanded position, the second balloon is expanded from the collapsed position to the expanded position for deploying the plurality of microprojections into tissue and for dispensing the therapeutic agent from the second balloon into the tissue through the plurality of apertures. The device is placed adjacent a site in the tissue; and the therapeutic agent is delivered into the tissue at the site by expanding the first balloon from the collapsed position to the expanded position.

摘要翻译： 将治疗剂递送到组织中的方法包括提供用于将治疗剂递送到组织中的装置。 该装置具有细长的主体; 主体中的第一气球从折叠位置伸展到展开位置; 主体中的第二气球从折叠位置伸展至展开位置。 第二气球在其中具有多个孔; 并且治疗剂位于第二气囊中。 多个微突出物位于第二球囊的用于穿透组织的表面上。 当第一气囊从折叠位置膨胀到扩张位置时，第二气囊从折叠位置膨胀到扩张位置，用于将多个微突出物展开到组织中，并且用于将治疗剂从第二气囊分配到组织中 多个孔。 该装置放置在组织中的一个位置附近; 并且通过将第一气囊从折叠位置膨胀到扩张位置，将治疗剂递送到该部位的组织中。

公开(公告)号：US20080026138A1

公开(公告)日：2008-01-31

申请号：US11827612

申请日：2007-07-11

申请人： Mariam Maghribi ,  Peter Krulevitch ,  Thomas Wilson ,  Julie Hamilton ,  Christina Park

发明人： Mariam Maghribi ,  Peter Krulevitch ,  Thomas Wilson ,  Julie Hamilton ,  Christina Park

IPC分类号： B05D5/12

CPC分类号： C08J5/18 ,  A61B5/04001 ,  A61B2562/02 ,  A61B2562/164 ,  A61N1/0452 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/05 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0541 ,  A61N1/0543 ,  A61N1/0551 ,  A61N1/0553 ,  C08J2383/04 ,  H05K1/0283 ,  H05K1/118 ,  H05K2201/0133 ,  H05K2201/09263 ,  H05K2203/0271 ,  Y10T428/24917 ,  Y10T428/31663 ,  Y10T428/31707

摘要： A stretchable electronic apparatus and method of producing the apparatus. The apparatus has a central longitudinal axis and the apparatus is stretchable in a longitudinal direction generally aligned with the central longitudinal axis. The apparatus comprises a stretchable polymer body, and at least one circuit line operatively connected to the stretchable polymer body, the at least one circuit line extending in the longitudinal direction and having a longitudinal component that extends in the longitudinal direction and having an offset component that is at an angle to the longitudinal direction, the longitudinal component and the offset component allowing the apparatus to stretch in the longitudinal direction while maintaining the integrity of the at least one circuit line.

摘要翻译： 一种可拉伸电子设备及其制造方法。 该装置具有中心纵向轴线，并且该装置在大致与中心纵向轴线对准的纵向方向上是可拉伸的。 该装置包括可拉伸的聚合物主体，以及至少一个可操作地连接到可拉伸聚合物主体的电路线，所述至少一个电路线在纵向上延伸并且具有沿纵向方向延伸的纵向部件，并且具有偏移部件， 与纵向方向成一角度，纵向分量和偏移分量允许装置在纵向方向上拉伸，同时保持至少一条电路线的完整性。