摘要:
A cyclopropane compound represented by the following formula (A) or a pharmaceutically acceptable salt thereof has orexin receptor antagonism, and therefore has a potencial of usefulness for the treatment of sleep disorder for which orexin receptor antagonism is effective, for example, insomnia: wherein Q represents —CH— or a nitrogen atom, R1a and R1b each independently represent a C1-6 alkyl group and the like, R1c represents a hydrogen atom and the like, R2a, R2b, R2c and R2d each independently represent a hydrogen atom, a halogen atom, a C1-6 alkyl group and the like, R3a, R3b and R3c each independently represent a hydrogen atom, a halogen atom and the like, and R3d represents a hydrogen atom and the like.
摘要翻译:由下式(A)表示的环丙烷化合物或其药学上可接受的盐具有食欲肽受体拮抗作用,因此具有治疗食欲肽受体拮抗作用有效的睡眠障碍的潜在用途,例如失眠症:其中Q表示 -CH-或氮原子,R1a和R1b各自独立地表示C1-6烷基等,R1c表示氢原子等,R2a,R2b,R2c和R2d各自独立地表示氢原子,卤素原子 C 1-6烷基等,R 3a,R 3b和R 3c各自独立地表示氢原子,卤素原子等,R 3d表示氢原子等。
摘要:
A cyclopropane compound represented by the following formula (A) or a pharmaceutically acceptable salt thereof has orexin receptor antagonism, and therefore has a potencial of usefulness for the treatment of sleep disorder for which orexin receptor antagonism is effective, for example, insomnia: wherein Q represents —CH— or a nitrogen atom, R1a and R1b each independently represent a C1-6 alkyl group and the like, R1c represents a hydrogen atom and the like, R2a, R2b, R2c and R2d each independently represent a hydrogen atom, a halogen atom, a C1-6 alkyl group and the like, R3a, R3b and R3c each independently represent a hydrogen atom, a halogen atom and the like, and R3d represents a hydrogen atom and the like.
摘要翻译:由下式(A)表示的环丙烷化合物或其药学上可接受的盐具有食欲肽受体拮抗作用,因此具有治疗食欲肽受体拮抗作用有效的睡眠障碍的潜在用途,例如失眠症:其中Q表示 -CH-或氮原子,R1a和R1b各自独立地表示C1-6烷基等,R1c表示氢原子等,R2a,R2b,R2c和R2d各自独立地表示氢原子,卤素原子 C 1-6烷基等,R 3a,R 3b和R 3c各自独立地表示氢原子,卤素原子等,R 3d表示氢原子等。
摘要:
A cyclopropane derivative represented by the following formula (I) or a pharmaceutically acceptable salt thereof has orexin receptor inhibitory action, and thus, is extremely useful as an agent for preventing or treating sleep disorder or dyssomnia caused by orexin, including insomnia as a typical example: wherein A1, A2 and A3 each independently represent an aryl group, a heterocyclyl group or the like, R1, R2 and R3 each independently represent a hydrogen atom, a C1-6 alkyl group or the like, X represents an oxygen atom or the like, and L represents a bond or the like.
摘要:
A video recorder includes a schedule reconfiguration section having: a local deterioration determining module that determines whether a local deterioration in a recording state occurs by performing simulating the recording state obtained when the reallocated resources are used for performing the programmed recordings and comparing the simulated recording state with a recording state obtained when the resources before the reallocation is used for performing the programmed recordings; and an allocation restoring module that restores the reallocated resources at a part causing the local deterioration to the resources allocated before the reallocation when the local deterioration determining module determines the occurrence of the local deterioration.
摘要:
An illuminating apparatus has a reduced number of mounting spots by soldering or the like to permit an increased yield rate and a reduced cost. The illuminating apparatus has light emitting diodes, lead frames, and a transparent sealer. N light emitting diodes, N sets of lead frames mounted with the N light emitting diodes, and one set or more of lead frames each not mounted with a light emitting diode are sealed by the transparent sealer for integration into a modular illuminating apparatus. Also provided are a method for fabricating the illuminating apparatus, and a display apparatus using the illuminating apparatus.
摘要:
According to an aspect of the embodiment, an area control unit refers to usage information of an area management table based on a determined type of an extracted failure information, determines whether the extracted failure information can be stored in a identified lower storage areas, determines a storage location for the extracted failure information in the identified lower storage areas when the extracted failure information can be stored in the identified lower storage areas, and determines a storage location for the extracted failure information in the upper storage areas other than an upper storage area including the identified lower storage areas based on the area management table when the extracted failure information cannot be stored in the identified lower storage areas.
摘要:
An exhaust emission control system of an internal combustion engine desorbs SOx by reversing a flow of an exhaust gas through an NOx storage-reduction catalyst, of which a structure is simplified as follows. A first exhaust pipe connected to an engine is connected to a first port of an emission switching valve having four ports. A second exhaust pipe 10, through which the exhaust gas is discharged into the atmospheric air, is connected to a second port, a third exhaust pipe connected to an inlet of a catalytic converter is connected to a third port. A fourth exhaust pipe connected to an outlet of the catalytic converter 30 is connected to a fourth port. When the emission switching valve is set in a forward flow position, the first exhaust pipe is connected to the third exhaust pipe, and the second exhaust pipe is connected to the fourth exhaust pipe, whereby the exhaust gas flows toward the outlet from the inlet within the catalytic converter. When the emission switching valve is set in a backward flow position, the first exhaust pipe is connected to the fourth exhaust pipe, and the second exhaust pipe is connected to the third exhaust pipe, whereby the exhaust gas flows toward the inlet from the outlet within the catalytic converter.
摘要:
In an examination system including a head mounted display having image pickup devices such as CCDs provided therein and a computer, coordinates of an image to be displayed in the head mounted display can be set object- or body-centered. An image captured by the image pickup device is supplied to the computer where it will be processed in a predetermined manner for display in the head mounted display.
摘要:
A cold-cathode tube has hitherto been used as a backlight for supplying illumination to a liquid crystal television but recently, light emitting diode pieces have been used for a backlight of a large-size liquid crystal television. For the purpose of improving the emission efficiency, flip chip mounting of the light emitting diode piece is advantageous but the mounting yield is restricted by the piece size, electrode structure and wire pattern structure, facing situations having difficulties in realizing simplified mounting and reduction of costs of members. In a liquid crystal display apparatus having a liquid crystal panel, an optical system and a light source, the light source includes a light emitting element structure having positive and negative electrodes, at least one of them being plural, and wires mounted to the positive and negative electrodes through flip chip mounting by making electrical correspondence to individual regions of the positive and negative electrodes.
摘要:
The present invention provides an illumination device capable of improving an efficiency of acquiring light emitted by light emitting diodes, which are provided in a light source module and used as a light source, and capable of achieving a uniform luminance distribution, and provides a liquid crystal display device using the illumination device. The illumination device includes a circuit board, red, green and blue light emitting diodes, and a lens body. Each red, green and blue light emitting diode is mounted on the circuit board and connected with a wiring pattern formed on the circuit board. The lens covers the red, green and blue light emitting diodes, and includes first portions each having two first side surfaces and second portions each having two second side surfaces. The first and second portions are alternately arranged. A distance between the first side surfaces is larger than a distance between the second side surfaces. The three red, green and blue light emitting diodes are provided in each first portion of the lens.