Production process of ethynylthymidine compounds from 5-methyluridine as a starting material
    1.
    发明授权
    Production process of ethynylthymidine compounds from 5-methyluridine as a starting material 失效
    以5-甲基尿苷为起始原料的乙炔基胸苷化合物的制备方法

    公开(公告)号:US08445669B2

    公开(公告)日:2013-05-21

    申请号:US12936789

    申请日:2009-04-10

    IPC分类号: C07H19/167

    摘要: The present invention provides a process for producing 2′,3′-didehydro-3′-deoxy-4′-ethynylthymidine, which is useful as a medicine, in an efficient and industrially advantageous manner, and more specifically, provides a process for producing 2′,3′-didehydro-3′-deoxy-4′-ethynylthymidine as shown below. (wherein R1 and R2 independently represent a protective group for a hydroxy group, or R1 and R2 together form a protective group for two hydroxy groups, R3 and R4 independently represent a protective group for a hydroxy group, R5 represents a protective group for a hydroxy group, R6 represents a protective group for a hydroxy group, X represents a leaving group, and Y represents a halogen atom.)

    摘要翻译: 本发明提供以有效和工业上有利的方式制备可用作药物的2',3'-二脱氢-3'-脱氧-4'-乙炔基胸苷的方法,更具体地说,提供了一种制备 2',3'-二脱氢-3'-脱氧-4'-乙炔基胸苷如下所示。 (其中R1和R2独立地表示羟基的保护基,或R1和R2一起形成两个羟基的保护基,R3和R4独立地表示羟基的保护基,R5表示羟基的保护基 基团,R6表示羟基的保护基,X表示离去基,Y表示卤素原子。)

    PRODUCTION PROCESS OF ETHYNYLTHYMIDINE COMPOUNDS FROM 5-METHYLURIDINE AS A STARTING MATERIAL
    2.
    发明申请
    PRODUCTION PROCESS OF ETHYNYLTHYMIDINE COMPOUNDS FROM 5-METHYLURIDINE AS A STARTING MATERIAL 失效
    作为起始材料的5-甲基缬氨酸的乙酰基亚胺化合物的生产工艺

    公开(公告)号:US20110054164A1

    公开(公告)日:2011-03-03

    申请号:US12936789

    申请日:2009-04-10

    IPC分类号: C07H19/06 C07H1/00

    摘要: The present invention provides a process for producing 2′,3′-didehydro-3′-deoxy-4′-ethynylthymidine, which is useful as a medicine, in an efficient and industrially advantageous manner, and more specifically, provides a process for producing 2′,3′-didehydro-3′-deoxy-4′-ethynylthymidine as shown below. (wherein R1 and R2 independently represent a protective group for a hydroxy group, or R1 and R2 together form a protective group for two hydroxy groups, R3 and R4 independently represent a protective group for a hydroxy group, R5 represents a protective group for a hydroxy group, R6 represents a protective group for a hydroxy group, X represents a leaving group, and Y represents a halogen atom.)

    摘要翻译: 本发明提供以有效和工业上有利的方式制备可用作药物的2',3'-二脱氢-3'-脱氧-4'-乙炔基胸苷的方法,更具体地说,提供了一种制备 2',3'-二脱氢-3'-脱氧-4'-乙炔基胸苷如下所示。 (其中R1和R2独立地表示羟基的保护基,或R1和R2一起形成两个羟基的保护基,R3和R4独立地表示羟基的保护基,R5表示羟基的保护基 基团,R6表示羟基的保护基,X表示离去基,Y表示卤素原子。)

    Switching regulator performing output voltage changing function
    3.
    发明授权
    Switching regulator performing output voltage changing function 有权
    开关稳压器执行输出电压变化功能

    公开(公告)号:US08692531B2

    公开(公告)日:2014-04-08

    申请号:US13360987

    申请日:2012-01-30

    申请人: Tetsuya Kawashima

    发明人: Tetsuya Kawashima

    IPC分类号: G05F1/00

    CPC分类号: H02M3/157 H02M2001/0025

    摘要: A switching regulator can convert an input voltage to a desired output voltage by ON-OFF controlling switching elements with PWM signals. The switching regulator can include a communication interface circuit that receives external operation instructions, an output voltage setting section that changes an output voltage to an output voltage setting value upon receiving an output voltage changing instruction from the outside, a voltage divider and an ADC that converts an error voltage into a digital error signal e[n], the error voltage being a difference between a reference voltage Vref and a detected output voltage value Vfb. The switching regulator can also include a controller that includes an operation control section for calculating a duty factor signal d[n] to determine an ON time proportion of the switching elements and an output voltage changing control section for controlling operation to change the output voltage.

    摘要翻译: 开关调节器可以通过ON-OFF将输入电压转换为期望的输出电压,从而控制具有PWM信号的开关元件。 开关调节器可以包括接收外部操作指令的通信接口电路,输出电压设定部,其在从外部接收到输出电压变化指令时,将输出电压变更为输出电压设定值,分压器和ADC 将误差电压转换为数字误差信号e [n],误差电压是参考电压Vref与检测的输出电压值Vfb之差。 开关调节器还可以包括控制器,其包括用于计算占空因数信号d [n]以确定开关元件的接通时间比例的操作控制部分和用于控制改变输出电压的操作的输出电压变化控制部分。

    Digitally controlled integrated DC-DC converter with transient suppression
    4.
    发明授权
    Digitally controlled integrated DC-DC converter with transient suppression 有权
    具有瞬态抑制功能的数字集成式DC-DC转换器

    公开(公告)号:US08441242B2

    公开(公告)日:2013-05-14

    申请号:US12794506

    申请日:2010-06-04

    IPC分类号: G05F1/00

    CPC分类号: H02M3/1584 H02M2001/009

    摘要: A fully integrated DC-DC converter utilizes digitally controlled dual output stages to achieve fast load transient recovery is presented. The DC-DC converter includes a main converter output stage connected in parallel with an auxiliary output stage. The main output stage is responsible for steady-state operation and is designed to achieve high conversion efficiency using large inductor and power transistors with low on-resistance. The auxiliary stage is responsible for transient suppression and is only active when a load transient occurs. The auxiliary output stage performs well with inductor and power transistors much smaller than those of the main switching stage and thus achieves well balanced power conversion efficiency and dynamic performance with a much smaller area penalty than previously described dual-output-stage converters.

    摘要翻译: 一个完全集成的DC-DC转换器采用数字控制双输出级来实现快速负载瞬态恢复。 DC-DC转换器包括与辅助输出级并联连接的主转换器输出级。 主输出级负责稳态运行,并设计为使用大电感和功率晶体管实现高转换效率,具有低导通电阻。 辅助级负责瞬态抑制,仅在发生负载瞬变时有效。 辅助输出级与主开关级的电感和功率晶体管相比表现良好,从而实现了良好平衡的功率转换效率和动态性能,具有比先前描述的双输出级转换器小得多的面积损失。

    DC-DC CONVERTER
    6.
    发明申请
    DC-DC CONVERTER 有权
    DC-DC转换器

    公开(公告)号:US20090096436A1

    公开(公告)日:2009-04-16

    申请号:US12132504

    申请日:2008-06-03

    IPC分类号: G05F1/00

    CPC分类号: H02M3/158

    摘要: A DC-DC converter includes a series circuit of a main switch and a choke coil and an output capacitor connected to one end of the series circuit and outputs a DC voltage from the one end of the series circuit. A first MOS transistor is connected in parallel to the series circuit and a second MOS transistor is connected in parallel to the output capacitor. A control circuit controls the gate voltages of the first MOS transistor and/or the second MOS transistor so that the first MOS transistor and/or the second MOS transistor outputs a changed target output voltage, whereby the output voltage is made equal to the target voltage at high speed.

    摘要翻译: DC-DC转换器包括主开关和扼流线圈的串联电路和连接到串联电路的一端的输出电容器,并从串联电路的一端输出直流电压。 第一MOS晶体管并联连接到串联电路,第二MOS晶体管并联连接到输出电容器。 控制电路控制第一MOS晶体管和/或第二MOS晶体管的栅极电压,使得第一MOS晶体管和/或第二MOS晶体管输出改变的目标输出电压,由此使输出电压等于目标电压 高速

    POWER CONVERSION APPARATUS
    7.
    发明申请
    POWER CONVERSION APPARATUS 有权
    功率转换装置

    公开(公告)号:US20140226380A1

    公开(公告)日:2014-08-14

    申请号:US14125924

    申请日:2012-09-20

    申请人: Tetsuya Kawashima

    发明人: Tetsuya Kawashima

    IPC分类号: H02M7/539

    摘要: A current flowing into one of half-bridge circuits of a power semiconductor module (10) is detected by corresponding one of current detection circuits (11a and 11b to 11f) through a current detection terminal provided in corresponding one of semiconductor switching devices (Q1 and Q2 to Q6) forming the half-bridge circuits and a current detection terminal provided in corresponding one of flywheel diodes (D1 and D2 to D6) back-to-back connected to the corresponding one of the semiconductor switching devices (Q1 and Q2 to Q6). A pulse voltage waveform indicating the current detected by the corresponding one of the current detection circuits (11a and 11b to 11f) is held for a predetermined period and converted into a stepwise voltage waveform by use of corresponding one of sample-and-hold circuits (14a, 14b and 14f), so that the voltage held by the corresponding one of the sample-and-hold circuits (14a, 14b and 14c) is transmitted to a control circuit (20) through corresponding one of insulating circuits (14a, 14b and 14c).

    摘要翻译: 流入功率半导体模块(10)的半桥电路之一的电流通过相应的一个电流检测电路(11a和11b至11f)通过设置在相应的一个半导体开关器件(Q1和 Q2和Q6)形成半桥电路,以及设置在相应的一个续流二极管(D1和D2至D6)中的电流检测端子,背对背连接到相应的一个半导体开关器件(Q1和Q2至Q6) )。 指示由相应的一个电流检测电路(11a和11b至11f)检测的电流的脉冲电压波形保持预定时间段,并且通过使用相应的一个采样和保持电路( 使得由相应的一个采样保持电路(14a,14b和14c)保持的电压通过相应的一个绝缘电路(14a,14b)传输到控制电路(20) 和14c)。

    Switching power supply system provided with under voltage lock out circuit
    8.
    发明授权
    Switching power supply system provided with under voltage lock out circuit 有权
    开关电源系统配有欠压锁定电路

    公开(公告)号:US08558527B2

    公开(公告)日:2013-10-15

    申请号:US13109331

    申请日:2011-05-17

    IPC分类号: G05F1/00

    摘要: A switching power supply system controlling switching operations of switching devices by a control circuit to convert an input voltage into a desired output voltage, the system being provided with a under voltage lock out circuit including: an input voltage detection unit detecting an input voltage and producing an input voltage digital signal corresponding to the input voltage Vin; and a voltage level comparison unit carrying out digital comparison of the input voltage digital signal with each of two voltage detection level data and outputting the results of the comparisons as an output signal, in which by changing voltage detection level data stored in two registers, desired voltage detection levels and hysteresis characteristic are easily actualized.

    摘要翻译: 一种开关电源系统,其通过控制电路来控制开关器件的开关动作,将输入电压转换成期望的输出电压,所述系统配备有欠压锁定电路,包括:输入电压检测单元,检测输入电压并产生 对应于输入电压Vin的输入电压数字信号; 以及电压电平比较单元,对输入电压数字信号与两个电压检测电平数据中的每一个进行数字比较,并输出比较结果作为输出信号,其中通过改变存储在两个寄存器中的电压检测电平数据为期望的 电压检测电平和滞后特性容易实现。