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    Microchip matrix device for duplicating and characterizing nucleic acids
    4.
    发明授权
    Microchip matrix device for duplicating and characterizing nucleic acids 有权
    用于复制和表征核酸的Microchip矩阵器件

    公开(公告)号：US07888074B2

    公开(公告)日：2011-02-15

    申请号：US10038284

    申请日：2002-01-02

    申请人： Ralf Ehricht ,  Thomas Ellinger ,  Jens Tuchscherer ,  Eugen Ermantraut ,  Siegfried Poser ,  Torsten Schulz

    发明人： Ralf Ehricht ,  Thomas Ellinger ,  Jens Tuchscherer ,  Eugen Ermantraut ,  Siegfried Poser ,  Torsten Schulz

    IPC分类号： C12P19/34 ,  C12M1/36 ,  G01N15/06

    CPC分类号： B01F13/0076 ,  B01L3/5027 ,  B01L3/508 ,  B01L2200/142 ,  B01L2300/0636 ,  B01L2300/0809 ,  B01L2400/0406 ,  B01L2400/0418

    摘要： The aim of the invention is to provide a device for duplicating and characterizing nucleic acids almost simultaneously and with a high sample throughput rate. The device consists of a chamber body with a recess whose edge sealingly holds an optically transparent chip. Said chip holds nucleic acids in individual spots on a detection surface. The chamber body is placed on an optically transparent chamber support with a bearing surface, in such a way that a capillary gap, which can be filled with a liquid sample, is formed between the detection surface of the chip facing towards the chamber support and said chamber support. The chamber body is provided with an inlet and an outlet, which are spatially separate from each other, and has a space, which laterally encompasses the chip and which has a gas reservoir. The chamber support is provided with heating elements.

    摘要翻译： 本发明的目的是提供一种用于几乎同时复制和表征核酸并具有高样品通过率的装置。 该装置包括具有凹口的腔体，其边缘密封地保持光学透明的芯片。 所述芯片将核酸保留在检测表面上的各个斑点中。 室体被放置在具有支承表面的光学透明室支撑件上，使得可以在面向腔室支撑件的芯片的检测表面之间形成可填充有液体样品的毛细管间隙，并且所述 室支持。 腔体设置有在空间上彼此分离的入口和出口，并且具有横向包围芯片并且具有气体储存器的空间。 腔室支撑件设有加热元件。

    Assay devices and methods for the detection of analytes
    9.
    发明申请
    Assay devices and methods for the detection of analytes 有权
    用于检测分析物的检测装置和方法

    公开(公告)号：US20110071038A1

    公开(公告)日：2011-03-24

    申请号：US12385805

    申请日：2009-07-14

    申请人： Eugen Ermantraut ,  Torsten Schulz ,  Thomas Ellinger ,  Daniel Weicherding

    发明人： Eugen Ermantraut ,  Torsten Schulz ,  Thomas Ellinger ,  Daniel Weicherding

    IPC分类号： C40B30/04 ,  C40B60/12

    CPC分类号： B01L3/502707 ,  B01L2300/0636 ,  B01L2300/069 ,  B01L2300/0877 ,  B01L2400/0481 ,  C12Q1/6834

    摘要： The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.

    摘要翻译： 本发明涉及用于进行测定的装置和方法，特别是用于确定一种或多种分析物的存在和/或量。 特别地，本发明涉及一种用于检测分析物的装置，包括位于第一表面和第二表面之间的可逆压缩基质，其中第二表面位于与第一表面相对的位置，并且其中第一表面 并且第二表面是可变的。 本发明还涉及使用这种装置用于检测一种或多种分析物的相应方法。