公开(公告)号：US5414187A

公开(公告)日：1995-05-09

申请号：US968998

申请日：1992-10-30

申请人： David L. King ,  Michael D. Cooper ,  William A. Sanderson

发明人： David L. King ,  Michael D. Cooper ,  William A. Sanderson

IPC分类号： B01J21/08 ,  B01J27/08 ,  B01J27/16 ,  B01J31/02 ,  B01J37/02 ,  C07C2/62 ,  C07C2/66 ,  C07C5/27 ,  C07C37/08 ,  C07C45/45 ,  C07C45/46 ,  C07C45/49 ,  C07C45/53 ,  C07C45/74 ,  C07C51/353 ,  C07C67/04 ,  C07C67/08 ,  C07C205/06 ,  C07C409/24 ,  C07C409/26 ,  C07D301/14 ,  C10G29/20

CPC分类号： B01J31/0259 ,  B01J27/08 ,  B01J31/0211 ,  B01J31/0225 ,  B01J31/0227 ,  B01J31/0231 ,  B01J31/0258 ,  B01J31/0271 ,  B01J37/0201 ,  C07C2/62 ,  C07C2/66 ,  C07C201/08 ,  C07C37/08 ,  C07C409/24 ,  C07C45/455 ,  C07C45/46 ,  C07C45/49 ,  C07C45/53 ,  C07C45/74 ,  C07C5/2794 ,  C07C51/353 ,  C07C67/04 ,  C07C67/08 ,  C07D301/14 ,  C10G29/205 ,  B01J21/08 ,  B01J2231/323 ,  B01J2531/48 ,  B01J27/16 ,  C07C2527/08 ,  C07C2527/10 ,  C07C2527/1213 ,  C07C2527/125 ,  C07C2527/126 ,  C07C2527/128 ,  C07C2527/133 ,  C07C2527/135 ,  C07C2527/14 ,  C07C2531/025 ,  Y02P20/52

摘要： The present invention provides a process for the conversion of a reactant into a reaction product in the presence of a novel acid catalyst complex comprising an organosulfonic acid having the formula[(R.sup.2 O).sub.2 P(O)].sub.y R(SO.sub.r R.sup.1).sub.xwherein R is an organo radical having at least one covalent carbon-fluorine bond, R.sup.1 is hydrogen, R.sup.1 is a hydrocarbyl radical having up to 20 carbon atoms or hydrogen, r is 2 or 3, x is an integer from 1 to 3, y is an integer of from 1 to 3 with the proviso that the phosphorus and the sulfur are covalently bonded to a carbon atom and which organosulfonic acid has been contacted with a Lewis Acid to produce a catalyst complex containing said Lewis Acid. In the elected claims, a process for providing a high octane alkylate stream by converting a mixture comprising isoparaffins and olefins into said alkylate in the presence of said acid catalyst complex, is described.

摘要翻译： 本发明提供了一种在包含具有式[（R 2 O）2 P（O）] y R（SOr R 1）x的有机磺酸的新型酸催化剂络合物的存在下将反应物转化为反应产物的方法，其中R是 具有至少一个共价碳 - 氟键的有机基团，R 1是氢，R 1是具有至多20个碳原子的烃基或氢，r是2或3，x是1至3的整数，y是 1至3，条件是磷和硫共价结合到碳原子上，并且有机磺酸已经与路易斯酸接触以产生含有路易斯酸的催化剂络合物。 在所选择的权利要求中，描述了在所述酸催化剂络合物的存在下，通过将包含异链烷烃和烯烃的混合物转化成所述烷基化物来提供高辛烷基烷基化物流的方法。

公开(公告)号：US4942218A

公开(公告)日：1990-07-17

申请号：US197459

申请日：1988-05-23

申请人： William A. Sanderson ,  David L. King

发明人： William A. Sanderson ,  David L. King

IPC分类号： C08G79/14

CPC分类号： C08G79/14

摘要： The present invention provides a method of making a polymer by reacting, in the absence of water, an organic compound having the general formula R-H wherein R represents an organo radical having at least one unsaturated carbon-carbon bond and H is covalently bonded to one of said carbons, with PX.sub.3, wherein X is a halide radical, and zirconium ions to yield a reaction product and oxidizing and hydrolyzing such reaction product to yield a polymer represented by the general formula Zr(O.sub.3 PR).sub.n wherein n varies from about 1 to about 2.5. R may comprise sulfonic acid groups or may comprise sulfonatable site for sulfonation during the oxidation step. In either case, the resulting product is useful as an acid catalyst.

摘要翻译： 本发明提供一种制备聚合物的方法，该方法通过在没有水的情况下使具有通式RH的有机化合物反应，其中R表示具有至少一个不饱和碳 - 碳键的有机基团，并且H共价键合至 所述碳与PX3反应，其中X为卤化物基团，锆离子产生反应产物，氧化和水解该反应产物，得到由通式Zr（O3PR）n表示的聚合物，其中n为约1至约 2.5。 R可以包含磺酸基团，或者可以包括在氧化步骤期间磺化的可磺化位点。 在任一情况下，所得产物可用作酸催化剂。

公开(公告)号：US5157197A

公开(公告)日：1992-10-20

申请号：US697318

申请日：1991-05-07

申请人： Michael D. Cooper ,  David L. King ,  William A. Sanderson

发明人： Michael D. Cooper ,  David L. King ,  William A. Sanderson

IPC分类号： B01J21/04 ,  B01J27/08 ,  B01J27/128 ,  B01J27/135 ,  B01J27/32 ,  B01J38/12 ,  C07B61/00 ,  C07C2/60 ,  C07C9/16 ,  C10G35/06

CPC分类号： B01J27/32 ,  B01J21/04 ,  B01J27/08 ,  B01J27/128 ,  B01J27/135 ,  B01J38/12 ,  C07C2/60 ,  C07C2521/04 ,  C07C2527/08 ,  C07C2527/10 ,  C07C2527/1213 ,  C07C2527/125 ,  C07C2527/126 ,  C07C2527/128 ,  C07C2527/133 ,  C07C2527/135 ,  C07C2527/14 ,  Y02P20/584

摘要： This invention is a process for the alkylation of isoparaffin with olefins using a catalyst system comprising certain transition aluminas promoted with a Lewis acid (preferably BF.sub.3), and free Lewis acid. The product alkylate is a complex mixture of branched paraffins suitable for use as a high octane blending component for motor fuels.

摘要翻译： 本发明是使用包含用路易斯酸（优选BF 3）促进的某些过渡氧化铝和游离路易斯酸的催化剂体系，用烯烃烷基化异链烷烃的方法。 产物烷基化物是适合用作机动燃料的高辛烷值混合组分的支链烷烃的复杂混合物。

公开(公告)号：US07947465B2

公开(公告)日：2011-05-24

申请号：US12187661

申请日：2008-08-07

申请人： William F. Link ,  Renato B. del Rosario ,  Randy V. Sweet ,  David L. King

发明人： William F. Link ,  Renato B. del Rosario ,  Randy V. Sweet ,  David L. King

IPC分类号： G01N33/00

CPC分类号： G01N33/54326 ,  G01N33/94 ,  G01N2446/00 ,  Y10T436/101666 ,  Y10T436/108331 ,  Y10T436/25125

摘要： Bodily fluid is analyzed for the presence of drugs of a selected panel of drugs in a simultaneous assay in which sample of the fluid is incubated with additional amounts of all drugs of the panel, antibodies specific to each of the drugs of the panel, and microparticles, the microparticles being divided into subsets, one subset for each drug in the panel and each subset distinguishable from the others. The incubation is performed in a liquid medium in which competitive binding occurs, the drugs in the sample competing with those added to the assay medium for binding to the antibodies. In one procedure, the added drugs are pre-coupled to the microparticles while the antibodies are not, and the incubation is followed by further incubating the microparticles with labeled ligands that have affinity for the antibodies. In an alternative procedure, the added drugs are not coupled to the microparticles but are pre-labeled, while the antibodies are pre-coupled to the microparticles, and the assay proceeds without further incubation. In both alternatives, the microparticles are ultimately recovered from the assay medium and from any unbound species, and the recovered microparticles are analyzed by flow cytometry to obtain indications of the presence of the various drugs in the sample in an inverse manner by detection of the label, each drug differentiable from the others by the distinguishing features of the microparticles.

摘要翻译： 在同时测定中分析体液中所选择的药物组的药物的存在，其中将流体样品与附加量的所有药物，面板每种药物特异的抗体和微粒 ，将微粒分为子集，面板中每种药物的一个子集，以及与其他子集可区分的每个子集。 孵育在其中发生竞争性结合的液体培养基中进行，样品中的药物与添加到测定培养基中的药物与抗体结合。 在一个程序中，将所添加的药物预先偶联到微粒，而不是抗体，然后孵育后，用对抗体具有亲和性的标记配体进一步孵育微粒。 在替代方法中，所添加的药物不与微粒偶联，而是预先标记，而抗体预偶联于微粒，并且测定在不进一步孵育的情况下进行。 在两种替代方案中，微粒最终从测定培养基和任何未结合物质中回收，并且通过流式细胞术分析回收的微粒，以通过检测标签以相反的方式获得样品中各种药物的存在的迹象 ，每种药物通过微粒的区别特征与其他药物不同。

公开(公告)号：US07520917B2

公开(公告)日：2009-04-21

申请号：US11061237

申请日：2005-02-18

申请人： Ward E. TeGrotenhuis ,  Robert S. Wegeng ,  Greg A. Whyatt ,  David L. King ,  Kriston P. Brooks ,  Victoria S. Stenkamp

发明人： Ward E. TeGrotenhuis ,  Robert S. Wegeng ,  Greg A. Whyatt ,  David L. King ,  Kriston P. Brooks ,  Victoria S. Stenkamp

IPC分类号： B01D53/14

CPC分类号： B01J19/0093 ,  B01J2219/00822 ,  B01J2219/00835 ,  B01J2219/00844 ,  B01J2219/00858 ,  B01J2219/00873 ,  B01J2219/00889 ,  B01J2219/00905 ,  B01J2219/00918 ,  B01J2219/00921 ,  C01B3/384 ,  C01B3/48 ,  C01B2203/0233 ,  C01B2203/0283 ,  C01B2203/044 ,  C01B2203/047 ,  C01B2203/066 ,  C01B2203/0822 ,  C01B2203/0827 ,  C01B2203/1288 ,  C01B2203/148 ,  C01B2203/1614 ,  C01B2203/1647 ,  Y02P20/128

摘要： A microchannel device includes several mass transfer microchannels to receive a fluid media for processing at least one heat transfer microchannel in fluid communication with a heat transfer fluid defined by a thermally conductive wall, and at several thermally conductive fins each connected to the wall and extending therefrom to separate the mass transfer microchannels from one another. In one form, the device may optionally include another heat transfer microchannel and corresponding wall that is positioned opposite the first wall and has the fins and the mass transfer microchannels extending therebetween.

摘要翻译： 微通道装置包括几个传质微通道，用于接收流体介质，用于处理至少一个与由导热壁限定的传热流体流体连通的传热微通道，以及各自连接到壁并从其延伸的多个导热翅片 以将质量传递微通道彼此分开。 在一种形式中，该装置可以可选地包括另一个传热微通道和与第一壁相对定位的相应的壁，并且具有在其间延伸的翅片和传质微通道。

公开(公告)号：US5352585A

公开(公告)日：1994-10-04

申请号：US084845

申请日：1993-06-29

申请人： Steven R. Binder ,  David L. King

发明人： Steven R. Binder ,  David L. King

IPC分类号： G01N30/02 ,  G01N30/06 ,  G01N30/08 ,  G01N30/14 ,  G01N30/34 ,  G01N30/46 ,  G01N30/74 ,  G01N30/86 ,  G01N30/88

CPC分类号： G01N30/461 ,  G01N30/88 ,  G01N2030/027 ,  G01N2030/085 ,  G01N2030/8804 ,  G01N2030/8813 ,  G01N2030/8831 ,  G01N30/02 ,  G01N30/06 ,  G01N30/14 ,  G01N30/34 ,  G01N30/468 ,  G01N30/74 ,  G01N30/8606 ,  G01N30/8679 ,  Y10S436/901 ,  Y10T436/14 ,  Y10T436/145555 ,  Y10T436/17 ,  Y10T436/25 ,  Y10T436/25125 ,  Y10T436/255

摘要： Biological samples are analyzed for benzodiazepines in a single isocratic analysis using a chromatographic column system containing an immobilized enzyme reactor which cleaves glucuronic acid-conjugated benzodiazepines, an anion exchange column, a hydrophobic cation exchange column and a reverse-phase analytical column. Preferred methods of performing the analysis further involve the use of a hydrophobic cation exchange precolumn prior to the anion exchange column. The system readily lends itself to automation, automatic periodic sampling and benzodiazepine identification and quantification. The system is particularly well adapted to the determination and identification of benzodiazepines in urine samples.

摘要翻译： 在使用含有固定化酶反应器的色谱柱系统的单一等度分析中分析生物样品中的苯并二氮杂，所述固定化酶反应器切割葡糖醛酸 - 共轭苯并二氮杂，阴离子交换柱，疏水性阳离子交换柱和反相分析柱。 执行分析的优选方法还涉及在阴离子交换柱之前使用疏水性阳离子交换预柱。 该系统易于自动化，自动定期取样和苯二氮卓鉴定和定量。 该系统特别适用于尿液样品中苯二氮卓类的测定和鉴定。

公开(公告)号：US5008468A

公开(公告)日：1991-04-16

申请号：US384251

申请日：1989-08-21

申请人： David L. King ,  Michael D. Cooper ,  Michael A. Faber

发明人： David L. King ,  Michael D. Cooper ,  Michael A. Faber

IPC分类号： B01J31/10 ,  B01J31/16 ,  B01J31/18 ,  C07C2/66 ,  C07C45/45 ,  C07C45/46 ,  C07C45/53 ,  C07C45/74 ,  C07C201/08 ,  C07C205/06

CPC分类号： C07C45/455 ,  B01J31/10 ,  B01J31/1658 ,  B01J31/185 ,  C07C2/66 ,  C07C45/46 ,  C07C45/53 ,  C07C45/74 ,  C07C67/04 ,  B01J2231/12 ,  B01J2231/20 ,  B01J2231/323 ,  B01J2231/52 ,  B01J2531/48 ,  C07C2531/06

摘要： This invention provides an improved process for the conversion of reactant into a reaction product, in the presence of a solid acid catalyst comprising sulfonic acid groups covalently bonded to a polymeric chain, wherein the improvement comprises increasing the rate of conversion, on an equivalent sulfonic acid basis, by providing, as said polymeric chain a compound represented by the general formula:M(O.sub.3 ZO.sub.x R).sub.nwherein M is a tetravalent metal ion; Z is a pentavalent atom, selected from the group consisting of elements of Group V of the Periodic Table of the Elements having an atomic weight greater than 30; x varies from 0 to 1; R is select d from the group consisting or organo radicals and mixtures of hydrogen radicals and organo radicals; and n varies from 1 to 2; provided that n is 1 when R is terminated with a tri- or tetraoxy pentavalent atom.

摘要翻译： 本发明提供了在包含共价键合到聚合物链上的磺酸基团的固体酸催化剂存在下将反应物转化成反应产物的改进方法，其中改进包括增加转化速率等同于磺酸 通过提供作为所述聚合物链的由通式M（O 3 Z x R）n表示的化合物，其中M是四价金属离子; Z是选自原子量大于30的元素周期表第Ⅴ族的元素的五价原子; x从0变化到1; R是选自下组的组或有机基团和氢基团和有机基团的混合物; n从1变化到2; 条件是当R用三或四氧基五价原子封端时n为1。

公开(公告)号：US08137987B2

公开(公告)日：2012-03-20

申请号：US13086229

申请日：2011-04-13

申请人： William F. Link ,  Renato B. del Rosario ,  Randy V. Sweet ,  David L. King

发明人： William F. Link ,  Renato B. del Rosario ,  Randy V. Sweet ,  David L. King

IPC分类号： G01N33/52 ,  G01N33/543

CPC分类号： G01N33/54326 ,  G01N33/94 ,  G01N2446/00 ,  Y10T436/101666 ,  Y10T436/108331 ,  Y10T436/25125

摘要： Bodily fluid is analyzed for the presence of drugs of a selected panel of drugs in a simultaneous assay in which sample of the fluid is incubated with additional amounts of all drugs of the panel, antibodies specific to each of the drugs of the panel, and microparticles, the microparticles being divided into subsets, one subset for each drug in the panel and each subset distinguishable from the others. The incubation is performed in a liquid medium in which competitive binding occurs, the drugs in the sample competing with those added to the assay medium for binding to the antibodies. In one procedure, the added drugs are pre-coupled to the microparticles while the antibodies are not, and the incubation is followed by further incubating the microparticles with labeled ligands that have affinity for the antibodies. In an alternative procedure, the added drugs are not coupled to the microparticles but are pre-labeled, while the antibodies are pre-coupled to the microparticles, and the assay proceeds without further incubation. In both alternatives, the microparticles are ultimately recovered from the assay medium and from any unbound species, and the recovered microparticles are analyzed by flow cytometry to obtain indications of the presence of the various drugs in the sample in an inverse manner by detection of the label, each drug differentiable from the others by the distinguishing features of the microparticles.

摘要翻译： 在同时测定中分析体液中所选择的药物组的药物的存在，其中将流体样品与附加量的所有药物，面板每种药物特异的抗体和微粒 ，将微粒分为子集，面板中每种药物的一个子集，以及与其他子集可区分的每个子集。 孵育在其中发生竞争性结合的液体培养基中进行，样品中的药物与添加到测定培养基中的药物与抗体结合。 在一个程序中，将所添加的药物预先偶联到微粒，而不是抗体，然后孵育后，用对抗体具有亲和性的标记配体进一步孵育微粒。 在替代方法中，所添加的药物不与微粒偶联，而是预先标记，而抗体预偶联于微粒，并且测定在不进一步孵育的情况下进行。 在两种替代方案中，微粒最终从测定培养基和任何未结合物质中回收，并且通过流式细胞术分析回收的微粒，以通过检测标签以相反的方式获得样品中各种药物的存在的迹象 ，每种药物通过微粒的区别特征与其他药物不同。

公开(公告)号：US07906085B2

公开(公告)日：2011-03-15

申请号：US11731116

申请日：2007-03-30

申请人： Liyu Li ,  David L. King

发明人： Liyu Li ,  David L. King

IPC分类号： B01D50/00

CPC分类号： B01D53/8609 ,  B01D53/9409 ,  B01D2251/20 ,  B01D2255/102 ,  B01D2255/1021 ,  B01D2255/104 ,  B01D2255/30 ,  B01D2257/302 ,  B01D2258/012 ,  B01J20/02 ,  B01J20/0251 ,  B01J20/041 ,  B01J20/06 ,  B01J20/08 ,  B01J20/103 ,  B01J20/16 ,  B01J20/18 ,  B01J20/3204 ,  B01J20/3236 ,  B01J23/40 ,  B01J23/50 ,  F23J2215/10 ,  F23J2215/20 ,  F23J2219/10 ,  F23J2219/60

摘要： Disclosed herein are sorbents and devices for controlling sulfur oxides emissions as well as systems including such sorbents and devices. Also disclosed are methods for making and using the disclosed sorbents, devices and systems. In one embodiment the disclosed sorbents can be conveniently regenerated, such as under normal exhaust stream from a combustion engine, particularly a diesel engine. Accordingly, also disclosed are combustion vehicles equipped with sulfur dioxide emission control devices.

摘要翻译： 本文公开了用于控制硫氧化物排放物的吸附剂和装置以及包括这种吸附剂和装置的系统。 还公开了制备和使用所公开的吸附剂，装置和系统的方法。 在一个实施方案中，所公开的吸附剂可以方便地再生，例如在来自内燃机，特别是柴油发动机的正常排气流下。 因此，还公开了配备有二氧化硫排放控制装置的燃烧车辆。

公开(公告)号：US07877913B1

公开(公告)日：2011-02-01

申请号：US11958250

申请日：2007-12-17

申请人： David L. King

发明人： David L. King

IPC分类号： G09F21/04

CPC分类号： G09F21/04 ,  G09F7/22 ,  G09F19/02 ,  G09F21/043

摘要： A multi-faceted, rotatable promotional display device for being retained relative to a vehicle for enabling the perception of multiple promotional messages from a single vantage point. A display casing with multiple display surfaces is rotatably retained relative to a base structure. Promotional messages are displayed relative to the display surfaces, and a drive arrangement rotates the display casing relative. The display casing can have a square, triangular, or other cross section. The base structure can have a cup portion with a raised peripheral ridge, and a shell can envelope the display casing. The display surfaces can be electronic display screens or light transmissive panels. A light source can be disposed within the display casing. A drive motor can be powered by a battery, a photovoltaic array, or a wind turbine. A clutch or a force sensor can prevent the application of excessive rotational force.

摘要翻译： 一种多面，可旋转的促销显示装置，用于相对于车辆保持，以使得能够从单个有利位置感知多个促销消息。 具有多个显示表面的显示壳体相对于基座结构可旋转地保持。 相对于显示表面显示促销消息，并且驱动装置相对于显示器壳体旋转。 显示器壳体可以具有正方形，三角形或其它横截面。 基部结构可以具有凸起的周缘的杯部，壳可以包围显示壳。 显示表面可以是电子显示屏或透光面板。 光源可以设置在显示器壳体内。 驱动电机可由电池，光伏阵列或风力涡轮机供电。 离合器或力传感器可以防止施加过大的旋转力。