-
公开(公告)号：USD667561S1
公开(公告)日：2012-09-18
申请号：US29384821
申请日：2011-02-04
Applicant: William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole
Designer： William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole
-
2.发明申请公开(公告)号：US20110117607A1
公开(公告)日：2011-05-19
申请号：US12617905
申请日：2009-11-13
Applicant: William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole , Christopher R. Kokaisel
Inventor： William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole , Christopher R. Kokaisel
CPC classification number: B01L7/52 , B01L2300/0803 , B01L2300/1811 , B01L2300/1822 , B01L2300/1827 , B01L2300/1883
Abstract: Systems and methods for processing sample processing devices. The system can include a base plate adapted to rotate about a rotation axis. The base plate can include at least one first magnetic element. The system can further include an annular cover, and a sample processing device comprising at least one thermal process chamber. The annular cover can include an inner edge, an outer edge, and at least one second magnetic element. The method can include positioning the sample processing device between the base plate and the annular cover, such that the inner edge of the annular cover is positioned inwardly of the at least one thermal process chamber, and such that the at least one first magnetic element attracts the at least one second magnetic element to force the annular cover in a first direction along the z-axis, urging the sample processing device into contact with the base plate.
Abstract translation: 用于处理样品处理装置的系统和方法。 该系统可以包括适于围绕旋转轴线旋转的基板。 基板可以包括至少一个第一磁性元件。 该系统还可以包括环形盖，以及包括至少一个热处理室的样品处理装置。 环形盖可以包括内边缘，外边缘和至少一个第二磁性元件。 该方法可以包括将样品处理装置定位在基板和环形盖之间，使得环形盖的内边缘位于至少一个热处理室的内部，并且使得至少一个第一磁性元件吸引 所述至少一个第二磁性元件沿着z轴沿第一方向推动所述环形盖，迫使所述样品处理装置与所述基板接触。
-
3.发明授权Methods for nucleic acid isolation and kits using a microfluidic device and concentration step 有权核酸分离方法和使用微流控装置和浓缩步骤的试剂盒公开(公告)号：US07939249B2
公开(公告)日：2011-05-10
申请号：US10852085
申请日：2004-05-24
Applicant: Ranjani V. Parthasarathy , Katya Ericson , William Bedingham
Inventor： Ranjani V. Parthasarathy , Katya Ericson , William Bedingham
IPC: C12Q1/68
CPC classification number: C12N15/10 , Y10T436/25
Abstract: The present invention provides methods and kits for isolating nucleic acid from a sample, preferably from a biological sample, using a microfluidic device and a concentration step.
Abstract translation: 本发明提供了使用微流体装置和浓缩步骤从样品，优选来自生物样品中分离核酸的方法和试剂盒。
-
4.发明授权公开(公告)号：US07867767B2
公开(公告)日：2011-01-11
申请号：US12419008
申请日：2009-04-06
Applicant: William Bedingham , Peter D. Ludowise , Barry W. Robole
Inventor： William Bedingham , Peter D. Ludowise , Barry W. Robole
CPC classification number: F16K99/003 , B01L3/502715 , B01L3/502738 , B01L2200/025 , B01L2300/021 , B01L2300/0806 , B01L2400/0409 , B01L2400/0677 , F16K99/0001 , F16K99/004 , F16K2099/0084 , G01N21/0332 , G01N21/07 , G01N21/359 , G01N21/6428 , G01N21/6452 , G01N35/00069 , G01N35/1097 , G01N2021/0325 , G01N2021/6421 , G01N2021/6441 , G01N2035/00267 , G01N2035/00415 , G01N2035/0474 , G01N2201/0407 , G01N2201/0415 , G01N2201/0612 , G01N2201/062 , G01N2201/0833 , Y10T436/11 , Y10T436/111666
Abstract: Techniques are described for the detection of multiple target species in real-time PCR (polymerase chain reaction). For example, a system comprises a data acquisition device and a detection device coupled to the data acquisition device. The detection device includes a rotating disk having a plurality of process chambers having a plurality of species that emit fluorescent light at different wavelengths. The device further includes a plurality of removable optical modules that are optically configured to excite the species and capture fluorescent light emitted by the species at different wavelengths. A fiber optic bundle coupled to the plurality of removable optical modules conveys the fluorescent light from the optical modules to a single detector. In addition, the device may control the flow of fluid in the disk by locating and selectively opening valves separating chambers by heating the valves with a laser.
Abstract translation: 描述了用于在实时PCR（聚合酶链式反应）中检测多种靶物种的技术。 例如，系统包括数据采集装置和耦合到数据采集装置的检测装置。 检测装置包括具有多个处理室的旋转盘，该多个处理室具有发射不同波长的荧光的多种物质。 该装置还包括多个可移除的光学模块，其被光学配置为激发物种并捕获由不同波长的物质发射的荧光。 耦合到多个可移除光学模块的光纤束将来自光学模块的荧光传送到单个检测器。 此外，该装置可以通过利用激光加热阀来定位和选择性地打开阀分离腔来控制盘中的流体流动。
-
公开(公告)号：US20100167304A1
公开(公告)日：2010-07-01
申请号：US12719704
申请日：2010-03-08
Applicant: William Bedingham , Barry W. Robole , Ranjani V. Parthasarathy , Katya Ericson
Inventor： William Bedingham , Barry W. Robole , Ranjani V. Parthasarathy , Katya Ericson
CPC classification number: B01L3/502738 , B01L2300/0806 , B01L2400/0409 , B01L2400/0677
Abstract: Sample processing devices with variable valve structures and methods of using the same are disclosed. The valve structures allow for removal of selected portions of the sample material located within the process chamber. Removal of the selected portions is achieved by forming an opening in a valve septum at a desired location. The valve septums may be large enough to allow for adjustment of the location of the opening based on the characteristics of the sample material in the process chamber. If the sample processing device is rotated after the opening is formed, the selected portion of the material located closer to the axis of rotation exits the process chamber through the opening. The remainder of the sample material cannot exit through the opening because it is located farther from the axis of rotation than the opening.
Abstract translation: 公开了具有可变阀结构的样品处理装置及其使用方法。 阀结构允许去除位于处理室内的样品材料的选定部分。 通过在期望的位置处在阀隔膜中形成开口来实现所选部分的移除。 阀隔件可以足够大以允许基于处理室中的样品材料的特性来调节开口的位置。 如果样品处理装置在形成开口后旋转，则位于更靠近旋转轴线的材料的选定部分通过开口离开处理室。 样品材料的其余部分不能通过开口离开，因为它比开口更远离旋转轴线。
-
Patent Agency Ranking
公开(公告)号：US20100136554A1
公开(公告)日：2010-06-03
申请号：US12597410
申请日：2008-04-25
Applicant: Ranjani V. Parthasarathy , Michael E. Danielson , John C. Faletti , William Bedingham
Inventor： Ranjani V. Parthasarathy , Michael E. Danielson , John C. Faletti , William Bedingham
CPC classification number: B01L3/5027 , B01L2200/12 , B01L2200/16 , B01L2300/0803 , B01L2300/0864 , B01L2300/0887 , G01N33/54366 , G01N33/54393
Abstract: Methods of providing at least one reagent for use in a device for processing sample material, delivering at least one reagent to a device for processing sample material, and adding at least one reagent to at least one of the steps in a process for detecting or assaying a nucleic acid; a support film coated with a dry reagent layer; and a device for processing sample material having a support film coated with a dry reagent layer contained within at least one chamber of the device are disclosed.
Abstract translation: 提供用于处理样品材料的装置中的至少一种试剂的方法，将至少一种试剂输送到用于处理样品材料的装置，以及在检测或测定方法中的至少一个步骤中加入至少一种试剂 核酸; 涂覆有干试剂层的支撑膜; 并且公开了一种用于处理样品材料的装置，其具有涂覆有包含在该装置的至少一个室中的干试剂层的支撑膜。
-
公开(公告)号：US07595200B2
公开(公告)日：2009-09-29
申请号：US11497828
申请日：2006-08-02
Applicant: William Bedingham , Chad J. Carter , Robert A. Harkins , Michael R. Harms , Christopher R. Kokaisel , Diane North , Kenneth B. Wood
Inventor： William Bedingham , Chad J. Carter , Robert A. Harkins , Michael R. Harms , Christopher R. Kokaisel , Diane North , Kenneth B. Wood
CPC classification number: G01N35/00069 , B01L3/5025 , B01L3/50255 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/0642 , B01L2200/0689 , B01L2200/142 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0406 , B01L2400/0409 , B01L2400/0481 , B01L2400/0655 , B01L2400/0661 , F27B9/16 , F27D5/00 , Y10T436/25 , Y10T436/2575
Abstract: Methods and devices for thermal processing of multiple samples at the same time are disclosed. The assemblies include carriers and sample processing devices with process arrays that include conduits useful in distributing sample materials to a group pf process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas. The carriers may be used to apply selective compression to the sample processing devices.
-
8.发明授权公开(公告)号：US07527763B2
公开(公告)日：2009-05-05
申请号：US11174957
申请日：2005-07-05
Applicant: William Bedingham , Peter D. Ludowise , Barry W. Robole
Inventor： William Bedingham , Peter D. Ludowise , Barry W. Robole
CPC classification number: F16K99/003 , B01L3/502715 , B01L3/502738 , B01L2200/025 , B01L2300/021 , B01L2300/0806 , B01L2400/0409 , B01L2400/0677 , F16K99/0001 , F16K99/004 , F16K2099/0084 , G01N21/0332 , G01N21/07 , G01N21/359 , G01N21/6428 , G01N21/6452 , G01N35/00069 , G01N35/1097 , G01N2021/0325 , G01N2021/6421 , G01N2021/6441 , G01N2035/00267 , G01N2035/00415 , G01N2035/0474 , G01N2201/0407 , G01N2201/0415 , G01N2201/0612 , G01N2201/062 , G01N2201/0833 , Y10T436/11 , Y10T436/111666
Abstract: Techniques are described for the detection of multiple target species in real-time PCR (polymerase chain reaction). For example, a system comprises a data acquisition device and a detection device coupled to the data acquisition device. The detection device includes a rotating disk having a plurality of process chambers having a plurality of species that emit fluorescent light at different wavelengths. The device further includes a plurality of removable optical modules that are optically configured to excite the species and capture fluorescent light emitted by the species at different wavelengths. A fiber optic bundle coupled to the plurality of removable optical modules conveys the fluorescent light from the optical modules to a single detector. In addition, the device may control the flow of fluid in the disk by locating and selectively opening valves separating chambers by heating the valves with a laser.
Abstract translation: 描述了用于在实时PCR（聚合酶链式反应）中检测多种靶物种的技术。 例如，系统包括数据采集装置和耦合到数据采集装置的检测装置。 检测装置包括具有多个处理室的旋转盘，该多个处理室具有发射不同波长的荧光的多种物质。 该装置还包括多个可移除的光学模块，其被光学配置为激发物种并捕获由不同波长的物质发射的荧光。 耦合到多个可移除光学模块的光纤束将来自光学模块的荧光传送到单个检测器。 此外，该装置可以通过利用激光加热阀来定位和选择性地打开阀分离腔来控制盘中的流体流动。
-
公开(公告)号：US20080152546A1
公开(公告)日：2008-06-26
申请号：US11962669
申请日：2007-12-21
Applicant: William Bedingham , Christopher R. Kokaisel , Peter D. Ludowise , Barry W. Robole
Inventor： William Bedingham , Christopher R. Kokaisel , Peter D. Ludowise , Barry W. Robole
CPC classification number: B01L3/502738 , B01F11/0074 , B01F13/0059 , B01F15/0233 , B01L3/50273 , B01L2200/0668 , B01L2200/0684 , B01L2300/0806 , B01L2400/0409 , B01L2400/0677 , Y10T137/0329 , Y10T137/0753 , Y10T137/7758
Abstract: Devices, systems, and methods for processing sample materials. The sample materials may be located in a plurality of process chambers in the device, which is rotated during heating of the sample materials.
Abstract translation: 用于处理样品的设备，系统和方法。 样品材料可以位于装置中的多个处理室中，其在样品材料的加热期间旋转。
-
10.发明申请Methods and devices for removal of organic molecules from biological mixtures using anion exchange 审中-公开使用阴离子交换从生物混合物中除去有机分子的方法和装置公开(公告)号：US20070160504A1
公开(公告)日：2007-07-12
申请号：US11709373
申请日：2007-02-22
Applicant: Ranjani Parthasarathy , Raj Rajagopal , Erin Olson , Frank Beissel , William Bedingham , Barry Robole
Inventor： Ranjani Parthasarathy , Raj Rajagopal , Erin Olson , Frank Beissel , William Bedingham , Barry Robole
IPC: B01L3/00
CPC classification number: C12N15/101 , B01F11/0002 , B01F13/0059 , B01F15/0201 , B01F15/0233 , B01J41/05 , B01J47/016 , B01L3/502753 , B01L2300/0806 , B01L2300/0864 , B01L2300/087 , B01L2400/0409 , B01L2400/0677 , B01L2400/0683 , Y10T436/25 , Y10T436/25125 , Y10T436/25375 , Y10T436/255 , Y10T436/2575
Abstract: Methods and devices for removing small negatively charged molecules from a biological sample mixture that uses an anion exchange material that has associated therewith a polyoxyalkylene.
Abstract translation: 用于从使用具有与其相关联的阴离子交换材料的生物样品混合物中去除小的带负电荷的分子的方法和装置。
-
-
-
-
-
-
-
-
-
Search Results
115
records
(took 0.038 seconds)
