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    APPARATUS AND METHOD FOR PERFORMING PASSIVE SENSING
    93.
    发明申请
    APPARATUS AND METHOD FOR PERFORMING PASSIVE SENSING 审中-公开
    执行被动感测的装置和方法

    公开(公告)号：US20160259041A1

    公开(公告)日：2016-09-08

    申请号：US15032592

    申请日：2014-10-30

    申请人： UCL BUSINESS PLC

    发明人： Bo Tan ,  Karl Woodbridge ,  Kevin Chetty

    IPC分类号： G01S13/00

    CPC分类号： G01S13/003 ,  G01S7/418 ,  G01S7/42 ,  G01S13/0218 ,  G01S13/58

    摘要： A method and an apparatus are provided for performing passing sensing using wireless digital communications. The wireless digital communications are frame-based with a predefined frame structure. The method includes receiving a reference signal into to a reference channel, wherein the reference signal comprises a direct version of a radio frequency transmission as part of said wireless digital communications; receiving a surveillance signal into a surveillance channel; detecting and extracting portions of the reference signal corresponding to data transmissions based on said predefined frame structure; extracting portions of the surveillance signal corresponding to the extracted portions of the reference signal; performing a cross-correlation on the extracted portions of the reference signal and the surveillance signal to determine a range-Doppler surface; and providing a real-time display of said range-Doppler surface and/or of information derived therefrom.

    摘要翻译： 提供了一种用于使用无线数字通信来执行传递感测的方法和装置。 无线数字通信是具有预定义帧结构的基于帧的。 该方法包括将参考信号接收到参考信道中，其中参考信号包括作为所述无线数字通信的一部分的射频传输的直接版本; 监视信号接收监控信号; 基于所述预定义的帧结构检测和提取对应于数据传输的参考信号的部分; 提取与参考信号的提取部分相对应的监视信号的部分; 对参考信号和监视信号的提取部分执行互相关，以确定范围 - 多普勒表面; 以及提供所述范围 - 多普勒表面和/或从其导出的信息的实时显示。

    ENZYME AND USES THEREOF
    97.
    发明申请
    ENZYME AND USES THEREOF 审中-公开
    酶及其用途

    公开(公告)号：US20160115466A1

    公开(公告)日：2016-04-28

    申请号：US14892881

    申请日：2014-05-16

    申请人： UCL BUSINESS PLC

    发明人： Peter Taylor ,  David Negus

    IPC分类号： C12N9/48 ,  A61K31/496 ,  C07K16/40 ,  A61K38/48

    CPC分类号： C12N9/485 ,  A61K31/496 ,  A61K38/00 ,  A61K38/4813 ,  C07K16/40 ,  C12N9/18 ,  C12Y304/19

    摘要： The present invention relates generally to methods and materials relating to newly characterised enzymes from Pusillimonas noertemannii, or variants thereof, capable degrading poly-γ-D-glutamic acid, for example as is present in the capsule of B. anthracis. Such depolymerases have utility as therapeutics.

    摘要翻译： 本发明一般涉及与来自白喉属（Pusillimonas noertemannii）的新近表征的酶相关的方法和材料，或其变体，其能够降解聚-γ-D-谷氨酸，例如存在于炭疽杆菌胶囊中。 这种解聚酶具有治疗作用。

    X-ray imaging
    99.
    发明授权
    X-ray imaging 有权
    X光成像

    公开(公告)号：US09171650B2

    公开(公告)日：2015-10-27

    申请号：US14233188

    申请日：2012-07-19

    申请人： Konstantin Ignatyev ,  Alessandro Olivo ,  Peter Munro ,  Robert Speller

    发明人： Konstantin Ignatyev ,  Alessandro Olivo ,  Peter Munro ,  Robert Speller

    IPC分类号： G21K1/06 ,  G01N23/20 ,  A61B6/00 ,  G01N23/04

    CPC分类号： G21K1/06 ,  A61B6/4233 ,  A61B6/4291 ,  A61B6/484 ,  A61B6/585 ,  A61B6/587 ,  G01N23/04 ,  G01N23/20075 ,  G01N2223/313 ,  G01N2223/401

    摘要： A method of aligning masks for phase imaging or phase contrast imaging in X-ray apparatus using a pixel-type X-ray detector makes use of non-idealities of all real detectors. A mask may be provided before the sample to generate beams, adjacent to the pixels of the detector or both. The method includes moving the mask into a plurality of translational position increments and identifying the increment for which the intensity has a maximum or minimum. The identified value of the increment may vary over the pixels of the detector. Alignment positions are selected in which steps in a plot of the increment over the area of the detector are minimized and/or aligned with the rows and columns of pixels.

    摘要翻译： 使用像素型X射线检测器在X射线设备中对准用于相位成像或相位对比成像的掩模的方法利用了所有真实检测器的非理想性。 可以在样品之前提供掩模以产生与检测器的像素相邻的光束或两者。 该方法包括将掩模移动到多个平移位置增量中并且识别强度具有最大或最小值的增量。 增量的识别值可以在检测器的像素上变化。 选择对准位置，其中在检测器的区域上的增量的图中的步骤被最小化和/或与像素的行和列对准。

    COMPOUNDS AND THEIR SYNTHESIS
    100.
    发明申请
    COMPOUNDS AND THEIR SYNTHESIS 审中-公开
    化合物及其合成

    公开(公告)号：US20150266818A1

    公开(公告)日：2015-09-24

    申请号：US14435046

    申请日：2013-10-14

    申请人： UCL BUSINESS PLC

    发明人： Erik Arstad ,  Kerstin Sander ,  Thibault Gendron

    IPC分类号： C07C381/12 ,  C07D211/20 ,  C07D403/06 ,  C07D207/46 ,  C07D213/70 ,  C07D213/61 ,  C07C45/65 ,  C07C49/807 ,  C07C47/55 ,  C07C67/317 ,  C07C69/78 ,  C07C17/361 ,  C07C25/13 ,  C07B59/00 ,  B01J20/22 ,  B01D15/08 ,  C07D211/32

    CPC分类号： C07C381/12 ,  B01D15/08 ,  B01J20/22 ,  C07B59/001 ,  C07B59/002 ,  C07C17/361 ,  C07C25/13 ,  C07C45/65 ,  C07C47/55 ,  C07C49/807 ,  C07C67/317 ,  C07C69/78 ,  C07D207/46 ,  C07D211/20 ,  C07D211/22 ,  C07D211/32 ,  C07D211/70 ,  C07D213/61 ,  C07D213/70 ,  C07D333/74 ,  C07D333/76 ,  C07D401/06 ,  C07D403/06

    摘要： The present invention relates to sulfonium salts of formula (I): (I), their preparation, and utility as precursors for preparing functionalised organic compounds, wherein R1 and R2 are the same or different and each is independently selected from an optionally substituted aryl group, an optionally substituted alkynyl group, an optionally substituted alkenyl group, an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted cycloalkenyl group, an optionally substituted aralkyl group, an optionally substituted arylalkenyl group, an optionally substituted heteroaryl group, an optionally substituted heterocyclyl group, an optionally substituted amine, an optionally substituted alkoxy group, an optionally substituted thioether group, an optionally substituted phosphine group, an optionally substituted boron species, an optionally substituted carbene, an organometallic moiety, and a halide, or R1 and R2 are joined together to form an optionally substituted sulfur-containing ring; W is a bond, an optionally substituted alkynylene group, an optionally substituted alkenylene group, and optionally substituted alkylene group, an optionally substituted heterocyclyl group, an optionally substituted aryl group or an optionally substituted heteroaryl group; R3 is a moiety comprising at least one basic group, provided that when R3 does not contain any carbon atoms, W is not a bond; X is an anionic species; and n is an integer selected from 1 to 5.

    摘要翻译： 本发明涉及式（I）的锍盐：（I），其制备和用作制备官能化有机化合物的前体，其中R 1和R 2相同或不同，并且各自独立地选自任选取代的芳基 ，任选取代的炔基，任选取代的烯基，任选取代的烷基，任选取代的环烷基，任选取代的环烯基，任选取代的芳烷基，任选取代的芳基烯基，任选取代的杂芳基， 任选取代的杂环基，任选取代的胺，任选取代的烷氧基，任选取代的硫醚基团，任选取代的膦基团，任选取代的硼物质，任选取代的卡宾，有机金属部分和卤化物，或R 1和 R2连接在一起形成一个选项 取代的含硫环; W是键，任选取代的亚炔基，任选取代的亚烯基和任选取代的亚烷基，任选取代的杂环基，任选取代的芳基或任选取代的杂芳基; R3是包含至少一个碱性基团的部分，条件是当R3不含任何碳原子时，W不是键; X是阴离子物种; n为1〜5的整数。