-
公开(公告)号：US10072285B2
公开(公告)日：2018-09-11
申请号：US14828242
申请日：2015-08-17
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Man Cheng , Xiao-Song Gong , Yan Wang , Adam M. McCoy
IPC: C12Q1/68 , C12Q1/6806 , C12P19/34 , C12Q1/686
CPC classification number: C12Q1/6806 , C07K2319/80 , C12N15/1096 , C12P19/34 , C12Q1/6853 , C12Q1/686 , C12Q2521/107 , C12Q2521/131 , C12Q2521/327 , C12Q2525/207 , C12Q2521/101 , C12Q2522/101
Abstract: Methods of detecting and amplifying short RNAs are provided.
-
公开(公告)号：US20180252676A1
公开(公告)日：2018-09-06
申请号：US15758445
申请日：2016-09-22
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Clayton McKee , Cory Panattoni , Paul Liu
IPC: G01N27/447 , G01N33/68
CPC classification number: G01N27/44747 , G01N27/44704 , G01N27/4473 , G01N27/44743 , G01N27/44782 , G01N33/6803
Abstract: Gel electrophoresis receptacles and methods of using such receptacles are provided. In one embodiment, a receptace comprises a cavity for receiving an electrophoresis gel, wherein at least a portion of the receptacle is formed from cyclic olefin copolymer or cyclic olefin polymer.
-
公开(公告)号：US10060847B2
公开(公告)日：2018-08-28
申请号：US15394624
申请日：2016-12-29
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Yunfeng Ling , David P. Stumbo , George Carman , Denis Pristinski
IPC: G01N15/14
CPC classification number: G01N15/1429 , G01N15/1404 , G01N15/1434 , G01N15/1459 , G01N2015/1461 , G01N2015/1488 , G01N2021/4707 , G01N2021/4728
Abstract: Systems and methods for detecting and processing signals from particles. In an exemplary method, particles may be passed through a zone of a channel, while the zone is irradiated with light. Interaction of the light with the particles may deflect light and induce photoluminescence. A deflection signal and a photoluminescence signal may be detected from the zone. Particle waveforms may be identified in the deflection signal. At least a subset of the particle waveforms may be double-peak waveforms including a pair of peaks corresponding to a particle entering and exiting the zone. Amplitudes may be obtained from the photoluminescence signal. The amplitudes may correspond to respective particles and their particle waveforms, and at least a subset of the amplitudes may correspond to the double-peak waveforms. Individual particles may be assigned as positive or as negative for an analyte based on the corresponding amplitudes.
-
公开(公告)号：US10022721B2
公开(公告)日：2018-07-17
申请号：US14470860
申请日：2014-08-27
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Sepehr Kiani , Joshua Blouwolff , Adnan Esmail , Jason Hung , Tony Hung , Adam R. Abate , Scott Powers , Pascaline Mary
Abstract: Methods and systems for manipulating drops in microfluidic channels are provided.
-
125.发明授权公开(公告)号：US10012592B2
公开(公告)日：2018-07-03
申请号：US15722486
申请日：2017-10-02
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Adam Abate , John Lawrence Emhoff , Tony Hung , Adnan Moez Esmail , Sepehr Kiani , Pascaline Mary
CPC classification number: G01N21/6486 , C12Q1/6806 , G01N21/255 , G01N21/76 , G01N2201/06113 , G01N2201/062 , C12Q2545/101 , C12Q2563/107 , C12Q2563/159 , C12Q2563/161 , C12Q2565/629
Abstract: The present invention generally pertains to methods and kits for managing the variation in spectroscopic intensity measurements through the use of a reference component. The reference component may comprise a reference spectroscopic substance and may be contained together with a sample of interest in a sample to be tested, wherein the sample of interest may comprise a sample spectroscopic substance. Each sample to be tested may be uniquely identified and, hence, “barcoded” by combinations of different colors and concentrations of spectroscopic substances, contained therein.
-
Patent Agency Ranking
公开(公告)号：US20180171387A1
公开(公告)日：2018-06-21
申请号：US15717103
申请日：2017-09-27
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Igor Kordunsky , Jeffrey A. Goldman , Michael J. Finney
CPC classification number: C12Q1/686 , B01L7/52 , B01L2300/0654 , B01L2300/0829 , B01L2300/1822 , G01N21/276 , G01N21/6452 , G01N2201/0446
Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.
-
公开(公告)号：US09971138B2
公开(公告)日：2018-05-15
申请号：US14262559
申请日：2014-04-25
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Michael Griffin , Daniel Yue Man Chu , Tom McCollum
CPC classification number: G02B21/06 , G02B21/125 , G02B21/16 , G02B21/24 , G02B21/365
Abstract: A system, apparatus and method for using modular microscopes is disclosed. Connecting the housings of the individual microscope modules provide the structural framework of the modular microscope. Furthermore, the modular microscope can include specialized software, the distribution and use of which can be controlled using security keys or identifiers stored on one or more of the microscope modules. The security keys and identifiers can be based on calibration data associated with the physical, electrical, or optical properties of one of more of the modules. The illumination modules disclosed provide for selectable wavelengths and controllable levels of output illumination for both bright field and dark field illumination.
-
公开(公告)号：US09927439B2
公开(公告)日：2018-03-27
申请号：US14261525
申请日：2014-04-25
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Ravi Kaul , Weiming Zheng , Roger Walker
IPC: C12Q1/68 , C12Q1/70 , A61K39/00 , A61K39/29 , C07K14/005 , G01N33/576 , G01N33/543
CPC classification number: G01N33/5761 , G01N33/54326
Abstract: Provided herein are multiplex assays for determining whether an individual is or has been infected with Hepatitis B virus, and the stage of infection or resolution. In addition, the multiplex system can discriminate between vaccinated subjects and subjects susceptible to Hepatitis B infection.
-
公开(公告)号：US09896717B2
公开(公告)日：2018-02-20
申请号：US14272370
申请日：2014-05-07
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Shawn Hodges , Nick Heredia , Jonathan Petersen
CPC classification number: C12Q1/6804 , C12Q2537/159 , C12Q2561/101 , C12Q2563/143 , C12Q2563/149
Abstract: The present invention provides methods of detecting an antigen in a sample comprising contacting the sample with affinity agents to form an antigen-affinity agent-label complex, separating the antigen-affinity agent-label complex from uncomplexed components, partitioning label from the separated sample into multiple partitions, and detecting the presence of the label in one or more partitions. Compositions and kits for detecting an antigen in a sample are also provided.
-
公开(公告)号：US09895693B2
公开(公告)日：2018-02-20
申请号：US14642487
申请日：2015-03-09
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Clayton T. McKee , William Strong
IPC: G01N33/543 , B01L3/00 , G01N27/447 , C12Q1/68
CPC classification number: B01L3/502738 , B01L2200/0605 , B01L2200/0642 , B01L2300/045 , B01L2300/047 , B01L2300/0816 , B01L2300/0874 , B01L2400/0415 , B01L2400/0418 , B01L2400/0421 , B01L2400/0487 , B01L2400/065 , C12Q1/6806 , G01N27/44717 , G01N27/44739 , G01N33/54366
Abstract: Devices, systems, methods, and kits are provided for performing separation, immobilization, blotting, and/or detection of analytes from biological samples. In some embodiments, the devices are constructed from two solid substrates with surfaces in contact. The devices include a plurality of channels formed from indentations in these surfaces. The indentations can be aligned with each other across the interface between the substrates, and realigned by shifting or sliding one substrate relative to the other. In some embodiments, the devices are constructed from three layers of a solid substrate. A separation channel in the middle layer of the device is first used for analyte separation. The middle layer can then be slid relative the top and/or bottom layer, thereby aligning the separation channel with a blotting membrane. Analytes can then be transferred to the membrane using electrodes in the top and bottom layers.
-
-
-
-
-
-
-
-
-
Search Results
1612
records
(took 0.032 seconds)
