ACTIVE INGREDIENT DELIVERY SYSTEM
    139.
    发明申请
    ACTIVE INGREDIENT DELIVERY SYSTEM 审中-公开
    主动成分交付系统

    公开(公告)号:US20140377364A1

    公开(公告)日:2014-12-25

    申请号:US14481650

    申请日:2014-09-09

    申请人: FIRMENICH SA

    摘要: A spray-chilled particulate delivery system that has a crystalline matrix structure and comprises a volatile hydrophobic active ingredient and a carrier material selected from the group consisting of erythritol and mannitol and mixtures thereof wherein, relative to the total weight of the carrier material, 75% or more of the carrier material is in crystalline form. The process for preparing the delivery system comprises the steps of (i) forming a melt of a carrier material selected from the group consisting of erythritol and mannitol and mixtures thereof (ii) incorporating a volatile hydrophobic active ingredient into the melt (iii) forming a melt-mixture comprising an emulsion, dispersion or suspension of the volatile hydrophobic active ingredient in the melt (iv) forming discrete particles of the melt mixture, and (v) cooling the discrete particles, so as to form the crystalline delivery system.

    摘要翻译: 具有结晶基质结构并包含挥发性疏水性活性成分和选自赤藻糖醇和甘露醇及其混合物的载体材料的喷雾冷却颗粒递送系统,其中相对于载体材料的总重量为75% 或更多的载体材料是结晶形式。 制备递送系统的方法包括以下步骤:(i)形成选自由赤藓糖醇和甘露糖醇组成的组的载体材料的熔体及其混合物(ii)将挥发性疏水性活性成分掺入到熔融物中,形成 熔融混合物,其包含在熔体(iv)中的挥发性疏水性活性成分的乳液,分散体或悬浮液,形成熔融混合物的离散颗粒,和(v)冷却离散颗粒,以形成结晶递送系统。