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151.发明申请公开(公告)号：US20160279202A1
公开(公告)日：2016-09-29
申请号：US15032835
申请日：2014-10-30
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD. , TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
Inventor： Yehuda KAMARI , Ruth SHALGI , Shiri URI , Dror HARATS , Aviv SHAISH
CPC classification number: A61K38/19 , A61K38/1774 , C12N5/0609 , C12N2501/2301 , C12N2501/31
Abstract: The invention provides IL-1 inhibitors, methods and uses thereof for retaining ovarian follicle reserve in a mammalian subject, treating infertility and improving responsiveness and sensitivity to COH. The invention further provides methods for improving oocyte quality and/or survival, specifically for IVF, and kits for combining COH treatment with the sensitizing IL-inhibitors of the invention.
Abstract translation: 本发明提供IL-1抑制剂，其用于在哺乳动物受试者中保留卵泡储备的方法和用途，治疗不孕症并改善对COH的反应性和敏感性。 本发明进一步提供了用于改善卵母细胞质量和/或存活的方法，特别是用于IVF，以及用于将COH处理与本发明的敏化IL-抑制剂组合的试剂盒。
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公开(公告)号：US20160270729A1
公开(公告)日：2016-09-22
申请号：US15037129
申请日：2014-11-17
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Tal DVIR , Yosi SHACHAM-DIAMAND , Ron FEINER , Leeya ENGEL
CPC classification number: A61B5/686 , A61B5/0031 , A61B5/0422 , A61B5/4848 , A61B5/6869 , A61B2562/164 , A61F2/24 , A61F2002/249 , A61K35/34 , A61L27/3604 , A61L2430/20 , A61N1/0563 , A61N1/0587 , A61N1/3621 , A61N1/395 , C12N5/0068 , C12N5/0657 , C12N2533/30 , C23C14/34
Abstract: A device comprising a three-dimensional polymeric element and an electronic element integrated with the polymeric element is disclosed. The electronic element is made up of one or more electrode(s) each individually connectable to a measuring device and/or a controller, and each independently having a thin electrically-isolating layer deposited thereon such that the electrode is exposed to an environment surrounding the electrode at one or more pre-determined locations over the electrode. The device can include cells and/or tissue and/or a therapeutically active agent incorporated within the polymeric material. Processes of fabricating the device, systems for operating the device and methods utilizing same are also disclosed.
Abstract translation: 公开了一种包括三维聚合元件和与该聚合物元件集成的电子元件的装置。 电子元件由单独可连接到测量装置和/或控制器的一个或多个电极组成，并且每个电极独立地具有沉积在其上的薄的电绝缘层，使得电极暴露于围绕 电极在电极上的一个或多个预定位置处。 该装置可包括掺入聚合材料内的细胞和/或组织和/或治疗活性剂。 还公开了制造器件的工艺，用于操作器件的系统和利用其的方法。
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公开(公告)号：US09427474B2
公开(公告)日：2016-08-30
申请号：US14816228
申请日：2015-08-03
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Ronit Satchi-Fainaro , Keren Miller , Doron Shabat , Rotem Erez
IPC: A61K31/74 , A61K47/48 , A61K49/00 , C07F9/38 , C07F9/655 , C07F9/6558 , C07K5/065 , C07K5/103 , A61K31/337 , A61K9/16
CPC classification number: A61K47/48084 , A61K9/1676 , A61K31/337 , A61K47/548 , A61K47/58 , A61K47/65 , A61K49/0017 , A61K49/0054 , A61K2800/57 , C07F9/3873 , C07F9/65517 , C07F9/65586 , C07K5/06078 , C07K5/1008
Abstract: Conjugates of polymers or copolymers having attached thereto an anti-angiogenesis agent and a bisphosphonate bone targeting agent, and processes of preparing same, are disclosed.Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of bone related disorders are also disclosed.
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公开(公告)号：US09402565B2
公开(公告)日：2016-08-02
申请号：US14874498
申请日：2015-10-05
Inventor： Yehuda Finkelstein , Lior Wolf
CPC classification number: A61B5/1075 , A61B5/08 , A61B5/4818 , G06K9/46 , G06T7/0014 , G06T7/33 , G06T2200/04 , G06T2207/10116 , G06T2207/30008 , G06T2207/30036 , G06T2207/30196
Abstract: In a method of analysis, a target image is registered to define a plurality of keypoints arranged in sets corresponding to polygons or linear segments in the target image. A database of registered and annotated images is accessed and a polygon-wise comparison between the target image and each database image is employed. The comparison is used for projecting annotated locations from the database images into the target image.
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公开(公告)号：US09394628B2
公开(公告)日：2016-07-19
申请号：US14061771
申请日：2013-10-24
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Ehud Gazit , Meital Reches
IPC: A61K38/00 , C07K16/00 , D01F4/00 , C07K5/065 , C07K5/06 , C08J5/18 , D01D5/00 , D01F1/10 , D01F6/68
CPC classification number: D01F4/00 , C07K5/06078 , C07K5/06191 , C08J5/18 , C08J2300/16 , D01D5/00 , D01F1/10 , D01F6/68 , Y10T428/253 , Y10T428/298 , Y10T442/60 , Y10T442/614
Abstract: A method of forming a fiber made of peptide nanostructures is disclosed. The method comprises: providing peptide nanostructures in solution, and fiberizing the solution thereby forming at least one fiber of the peptide nanostructures. Also disclosed are methods of forming films and other articles using the peptide nanostructures.
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Patent Agency Ranking
公开(公告)号：US20160204283A1
公开(公告)日：2016-07-14
申请号：US14912407
申请日：2014-08-11
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
Inventor： Fernando PATOLSKY , Alon KOSLOFF
IPC: H01L31/028 , H01L31/0224 , H01L31/18 , H01L31/0352 , H01L31/0745
CPC classification number: H01L31/028 , H01L21/0245 , H01L21/0251 , H01L21/02513 , H01L21/02532 , H01L21/02603 , H01L21/0262 , H01L21/02653 , H01L31/022425 , H01L31/035227 , H01L31/03529 , H01L31/0687 , H01L31/0725 , H01L31/0745 , H01L31/1812 , Y02E10/544
Abstract: A photovoltaic cell device is disclosed. The device comprises: an active region having a plurality of spaced-apart elongated nanostructures aligned vertically with respect to an electrically conductive substrate, wherein each elongated nanostructure has at least one p-n junction characterized by a bandgap within the electromagnetic spectrum, and is coated by an electrically conductive layer being electrically isolated from the substrate.
Abstract translation: 公开了一种光电池装置。 该器件包括：有源区，其具有相对于导电衬底垂直排列的多个间隔开的细长纳米结构，其中每个细长纳米结构具有至少一个pn结，其特征在于电磁光谱内的带隙，并且由 导电层与衬底电隔离。
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157.发明申请DIAGNOSTIC AND MONITORING ELECTRICAL IMPEDANCE TOMOGRAPHY (EIT) SYSTEM FOR OSTEOPOROSIS 审中-公开诊断和监测电磁阻抗（EIT）系统用于骨质疏松症公开(公告)号：US20160100791A1
公开(公告)日：2016-04-14
申请号：US14893109
申请日：2014-05-26
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
Inventor： Shimon ARAD (ABBOUD) , Sharon ZLOCHIVER , Muhammad MAHAJNA
CPC classification number: A61B5/4509 , A61B5/053 , A61B5/0536 , A61B5/6831
Abstract: A method of measuring Bone Mineral Density (BMD) including providing a model of a plurality of constituents of at least a portion of a subject body, the model including at least one bone constituent, injecting electric current into the portion of the subject body using a current injection electrode, such that at least part of the current flows through the at least one bone constituent, measuring a value of electric potential at a surface of the subject body using a pickup electrode, using a value of the injected electric current as input to a model of the at least a portion of a subject body, and calculating a value of conductance of the bone constituent corresponding to a value of the injected electric current and the measured value of the electric potential. Related apparatus and methods are also described.
Abstract translation: 一种测量骨密度（BMD）的方法，包括提供主体的至少一部分的多个成分的模型，所述模型包括至少一个骨成分，使用 电流注入电极，使得至少一部分电流流过至少一个骨成分，使用注入的电流的值作为输入来测量使用拾取电极的被检体的表面处的电位值 主体的至少一部分的模型，以及计算与注入的电流的值对应的骨成分的电导值和电位的测定值。 还描述了相关装置和方法。
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公开(公告)号：US20160043732A1
公开(公告)日：2016-02-11
申请号：US14922165
申请日：2015-10-25
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Yossef EHRLICHMAN , Ofer AMRANI , Shlomo RUSCHIN
IPC: H03M1/70 , H04B10/516
CPC classification number: H04B10/516 , G02F1/0121 , G02F1/015 , G02F1/225 , G02F7/00 , G02F2001/212 , G02F2203/19 , H03M1/002 , H03M1/70 , H04B10/2504 , H04B10/2575 , H04B10/505 , H04B10/5055 , H04B10/541 , H04B10/556
Abstract: A modulator device for converting digital data into modulation of an optical signal includes an electronic input for receiving an input data word of N bits and an electrically controllable modulator for modulating the intensity of an optical signal, the modulator including M actuating electrodes where M≧N. An electrode actuating device, most preferably a digital-to-digital converter, operates actuating electrodes so that at least one electrode is actuated as a function of values of more than one bit of the input data word. According to an alternative, or supplementary, aspect of the invention, the set of electrodes includes at least one electrode having an effective area which is not interrelated to others of the set by factors of two. In one preferred implementation, a Mach-Zehnder modulator also provides phase modulation to give QAM functionality. Another implementation employs a semiconductor laser.
Abstract translation: 用于将数字数据转换为光信号调制的调制器装置包括用于接收N位输入数据字的电子输入端和用于调制光信号强度的电可控调制器，该调制器包括M个致动电极，其中M≥N 。 电极致动装置，最优选数字 - 数字转换器，操作致动电极，使得至少一个电极作为输入数据字的多于一位的值的函数被致动。 根据本发明的替代或补充方面，所述电极组包括至少一个电极，所述至少一个电极具有与所述组合中的其它因素不相关的有效面积。 在一个优选实施例中，马赫 - 曾德调制器还提供相位调制以提供QAM功能。 另一个实施方案采用半导体激光器。
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公开(公告)号：US20160027162A1
公开(公告)日：2016-01-28
申请号：US14810295
申请日：2015-07-27
Applicant: Ramot at Tel-Aviv University Ltd. , Tel HaShomer Medical Research Infrastructure and Services Ltd.
Inventor： Hedva SPITZER , Yuval BARKAN , Lonia KANELOVITCH , Itzchak YACOV , Arie RUNDSTEIN , Miriam SKLAIR-LEVY
CPC classification number: G06T5/40 , G06T5/008 , G06T5/009 , G06T2207/10072 , G06T2207/10081 , G06T2207/10084 , G06T2207/10124 , G06T2207/30068 , H04N1/387 , H04N1/407
Abstract: A method of processing an image having a plurality of picture-elements is disclosed. The method comprises: preprocessing the image to selectively enhance contrast of some picture-elements of the image, and employing a companding procedure for the preprocessed image, thereby providing a processed image. The contrast enhancement optionally and preferably features a mapping function having a plateau region for diminishing image data with intensity levels below an intensity threshold, thereby providing a preprocessed image.
Abstract translation: 公开了一种处理具有多个像素的图像的方法。 该方法包括：对图像进行预处理以选择性地增强图像的一些图像元素的对比度，并对预处理的图像采用压扩过程，从而提供经处理的图像。 对比度增强可选地并且优选具有映射功能，其具有用于减小强度水平低于强度阈值的图像数据的平台区域，从而提供预处理的图像。
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160.发明申请INTRAVASCULAR PRESSURE DROP DERIVED ARTERIAL STIFFNESS AND REDUCTION OF COMMON MODE PRESSURE EFFECT 审中-公开血管压力下降导致的动脉硬化和减少共模压力的影响公开(公告)号：US20160000341A1
公开(公告)日：2016-01-07
申请号：US14768461
申请日：2014-02-18
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
Inventor： Oren ROTMAN , Shmuel EINAV
IPC: A61B5/0215 , A61B5/00 , A61B18/14
CPC classification number: A61B5/02158 , A61B5/02007 , A61B5/0215 , A61B5/7225 , A61B18/1492 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642
Abstract: In some embodiments, a method and/or device are disclosed for measuring a pressure drop over a portion of a body lumen. Optionally, the pressure drop for two different flow conditions may be used to find the stiffness of the lumen. In some embodiments the device may be calibrated, for example by correcting for distortion, for example the common mode pressure distortion. Pressure drop and or stiffness measures may be used to evaluate a treatment procedure and/or a stenosis.
Abstract translation: 在一些实施例中，公开了用于测量身体腔的一部分上的压降的方法和/或装置。 可选地，可以使用两种不同流动条件的压降来找到内腔的刚度。 在一些实施例中，该装置可以被校准，例如通过校正失真，例如共模压力失真。 压降和/或刚度测量可用于评估治疗程序和/或狭窄。
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