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    Thermal Device, System, and Method, for Fluid Processing Device
    12.
    发明申请
    Thermal Device, System, and Method, for Fluid Processing Device 审中-公开
    用于流体处理装置的热装置，系统和方法

    公开(公告)号：US20090325277A1

    公开(公告)日：2009-12-31

    申请号：US12552218

    申请日：2009-09-01

    申请人： John S. Shigeura ,  Janice G. Shigeura ,  Sean M. Desmond ,  David M. Cox

    发明人： John S. Shigeura ,  Janice G. Shigeura ,  Sean M. Desmond ,  David M. Cox

    IPC分类号： C12M1/34

    CPC分类号： G05D23/24 ,  G05D23/192 ,  G05D23/20 ,  G05D23/22 ,  Y02P20/129 ,  Y10S435/809

    摘要： A device, system, and method are provided for thermally treating a fluid processing device. According to various embodiments, a system is provided that can include a thermal device and a fluid processing device holder. The thermal device can include a first block having a thermal conductivity greater than 0.5 Watt per centimeter Kelvin (W/cm·K), a second block having a thermal conductivity greater than 0.5 W/cm·K, and a heat-pump device disposed between the first block and the second block. The heat-pump device can transfer thermal energy from at least one of the first block and the second block to the other of the first block and the second block. The fluid processing device holder can hold a fluid processing device in a heat-transfer position with respect to the first block and the second block. The fluid processing device can be a microfluidic device.

    摘要翻译： 提供了用于热处理流体处理装置的装置，系统和方法。 根据各种实施例，提供一种可以包括热装置和流体处理装置支架的系统。 热装置可以包括具有大于0.5瓦/厘米开尔文（W / cm·K）的热导率的第一块，具有大于0.5W / cm·K的热导率的第二块，以及设置在所述热泵装置 在第一块和第二块之间。 热泵装置可以将热能从第一块和第二块中的至少一个传递到第一块和第二块中的另一个块。 流体处理装置保持器可以将流体处理装置保持在相对于第一块和第二块的热传递位置。 流体处理装置可以是微流体装置。

    Apparatus for the precise location of reaction plates
    13.
    发明授权
    Apparatus for the precise location of reaction plates 失效
    用于反应板精确定位的装置

    公开(公告)号：US06878341B2

    公开(公告)日：2005-04-12

    申请号：US10010659

    申请日：2001-12-06

    申请人： Reid Burton Kowallis ,  David M. Cox

    发明人： Reid Burton Kowallis ,  David M. Cox

    IPC分类号： G01N35/02 ,  B01J19/00 ,  B01L3/00 ,  B01L3/02 ,  C40B20/02 ,  C40B60/10 ,  G01N35/10 ,  G01L35/02

    CPC分类号： B01L3/5085 ,  G01N35/1065 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114165 ,  Y10T436/2575

    摘要： Generally, the present invention provides a device and method for accurately locating a multi-well plate at a plate-support location, e.g., a work surface, of an automated laboratory machine, such that one or more acting members of the machine, such as an array of pipette tips, optical sensors, or the like, can accurately address and operate on the individual wells. Interior and/or exterior surface regions of one or more wells of a multi-well plate are used as the primary plate features engaged by locating structure of the machine. In one particular embodiment one or more upwardly tapered projections extend from a plate-support surface of a plate-handling machine for mating engagement with the exterior surface regions of one or more wells. In another embodiment, the exterior surface regions along one or more well bottoms are engagingly received within bores, or other receiving structure, formed on the place-support surface of a machine. In a further embodiment, one or more downwardly extending projections depend from an acting-member support, along with the acting members of a machine. Introduction of the projections into some of the wells of a multi-well plate serves to align the acting members with the plate's other wells.

    摘要翻译： 通常，本发明提供了一种用于在自动化实验室机器的板支撑位置（例如工作表面）处精确地定位多孔板的装置和方法，使得机器的一个或多个作用构件，例如 移液管尖端，光学传感器等的阵列可以精确地解决和操作各个井。 使用多孔板的一个或多个孔的内部和/或外部表面区域作为通过定位机器的结构而接合的主要板材特征。 在一个特定实施例中，一个或多个向上锥形突起从板处理机的板支撑表面延伸，用于与一个或多个井的外表面区域配合接合。 在另一个实施例中，沿着一个或多个井底的外表面区域被啮合地容纳在形成在机器的位置支撑表面上的孔或其它接收结构内。 在另一个实施例中，一个或多个向下延伸的突起与作用构件支撑件一起，与机器的作用构件一起。 将突出物引入多孔板的一些孔中用于使作用构件与板的其它孔对齐。

    Method for representing scalar data dependences for an optimizing compiler
    14.
    发明授权
    Method for representing scalar data dependences for an optimizing compiler 失效
    用于表示优化编译器的标量数据依赖的方法

    公开(公告)号：US5107418A

    公开(公告)日：1992-04-21

    申请号：US571503

    申请日：1990-08-23

    申请人： Timothy J. Cramer ,  David M. Cox

    发明人： Timothy J. Cramer ,  David M. Cox

    IPC分类号： G06F9/44 ,  G06F9/45 ,  G06F11/36 ,  G06F12/02 ,  G06F12/08 ,  G06F12/12

    CPC分类号： G06F8/41 ,  G06F12/023 ,  G06F12/08 ,  G06F12/12 ,  G06F8/433 ,  G06F8/445 ,  G06F8/45 ,  G06F9/3838

    摘要： A method for representing scalar data dependencies for an optimizing compiler wherein a global scalar data dependence graph is created to represent all of the scalar objects in an entire program. The scalar data dependencies are represented as three chains: a use-definition chain (ud); a definition-use chain (du) or a definition-definition chain (dd), and is created for the entire program and is maintained during the entire compilation or assembly of the program. The method for determining scalar data dependences for the entire program starts by analyzing the scalar data dependences within each basic block, in a single pass, processes all definitions and uses of all non-array data objects in the basic block, including simple variables and complex data objects such as records, unions, pointers and procedure calls in the presence of aliasing. From these objects, information is collected, such as whether the data objects are upwardly or downwardly exposed, pointers, pointer aliases, aggregate objects, array objects, uses, definitions; whether they are calls, indirect uses, or indirect definitions.

    摘要翻译： 一种用于表示优化编译器的标量数据依赖性的方法，其中创建全局标量数据依赖图以表示整个程序中的所有标量对象。 标量数据依赖性表示为三个链：一个使用定义链（ud）; 定义 - 使用链（du）或定义定义链（dd），并且是为整个程序创建的，并在程序的整个编译或汇编过程中被维护。 用于确定整个程序的标量数据依赖性的方法首先通过分析每个基本块中的标量数据依赖关系，在单个过程中，处理基本块中所有非数组数据对象的所有定义和使用，包括简单变量和复数 在存在混叠的情况下，记录，联合，指针和过程调用等数据对象。 从这些对象中，收集信息，例如数据对象是向上还是向下暴露，指针，指针别名，聚合对象，数组对象，使用，定义; 无论是电话，间接使用还是间接定义。

    Method for Triggering Dependent Spectra for Data Acquisition
    19.
    发明申请
    Method for Triggering Dependent Spectra for Data Acquisition 有权
    用于触发依赖光谱数据采集的方法

    公开(公告)号：US20130289894A1

    公开(公告)日：2013-10-31

    申请号：US13995816

    申请日：2011-12-22

    申请人： David M. Cox ,  Stephen A. Tate ,  Matthias Glueckmann

    发明人： David M. Cox ,  Stephen A. Tate ,  Matthias Glueckmann

    IPC分类号： G01N23/00 ,  H01J49/02

    CPC分类号： G01N23/00 ,  H01J49/0031 ,  H01J49/0045 ,  H01J49/025

    摘要： Methods and systems are provided for triggering an information dependent mass spectrometry scan in real time. A mass spectrometry scan of a separating sample mixture is performed by a mass spectrometer at each time interval of a time period. The mass spectrometer receives the separating sample mixture from a separation device. It is determined at a certain time interval that a received mass spectrometry scan at the time interval and one or more preceding received mass spectrometry scans include two or more time-varying ion signals that represent two or more fragment ion transitions of a known compound. If a characteristic of the two or more time-varying ion signals meets a selection criterion, the mass spectrometer is instructed to perform a dependent mass spectrometry scan of the separating sample mixture for a precursor ion of the known compound at the time interval.

    摘要翻译： 提供了实时触发信息依赖质谱扫描的方法和系统。 分离样品混合物的质谱扫描由质谱仪在每个时间段的每个时间间隔进行。 质谱仪从分离装置接收分离样品混合物。 在一定时间间隔确定在时间间隔和一个或多个先前接收质谱扫描的接收质谱扫描包括表示已知化合物的两个或更多个片段离子转变的两个或更多个时变离子信号。 如果两个或更多个时变离子信号的特征满足选择标准，则指示质谱仪以时间间隔对已知化合物的前体离子进行分离样品混合物的依赖性质谱扫描。

    Liquid processing device including gas trap, and system and method
    20.
    发明授权
    Liquid processing device including gas trap, and system and method 失效
    液体处理装置，包括气体捕集器，以及系统和方法

    公开(公告)号：US07737093B2

    公开(公告)日：2010-06-15

    申请号：US12246828

    申请日：2008-10-07

    申请人： David M. Cox

    发明人： David M. Cox

    IPC分类号： G01N1/10 ,  G01N1/02 ,  G01N1/00

    CPC分类号： B01L3/502738 ,  B01L2300/0803 ,  B01L2300/0864 ,  B01L2300/087 ,  B01L2400/0409 ,  B01L2400/0487 ,  B01L2400/0683 ,  Y10T436/11 ,  Y10T436/111666

    摘要： A device is provided that can include at least one gas trap that can be arranged in fluid communication with a sample-containment feature formed in or on the device. The gas trap can be arranged to trap gas or air displaced from the sample-containment feature as the sample-containment feature is loaded with a liquid. The trapped gas in the gas trap can assist in breaking-up and expelling the liquid from the sample-containment feature during a subsequent liquid transfer operation, for example, to an adjacent sample-containment feature. Systems for processing such a device and methods using such a device are also provided.

    摘要翻译： 提供了一种装置，其可以包括至少一个气体捕集器，其可以被布置成与形成在装置中或装置上的样品容纳特征流体连通。 气体捕集器可以布置成捕集从样品容纳特征中移出的气体或空气，因为样品容纳特征装载有液体。 在随后的液体转移操作期间，例如在相邻的样品容纳特征中，气阱中的被捕获的气体可以帮助分解和排出来自样品容纳特征的液体。 还提供了用于处理这种设备的系统和使用这种设备的方法。