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35 条记录 (耗时 0.037 秒)

    Peripheral nerve field stimulation control
    11.
    发明授权
    Peripheral nerve field stimulation control 有权
    外周神经域刺激控制

    公开(公告)号：US08805518B2

    公开(公告)日：2014-08-12

    申请号：US12359001

    申请日：2009-01-23

    申请人： Gary W. King ,  Steven M. Goetz ,  Andrew H. Houchins ,  Jeffrey T. Keacher ,  Jordan J. Greenberg ,  Kenneth T. Heruth ,  Mark S. Lent ,  Paul W. Wacnik

    发明人： Gary W. King ,  Steven M. Goetz ,  Andrew H. Houchins ,  Jeffrey T. Keacher ,  Jordan J. Greenberg ,  Kenneth T. Heruth ,  Mark S. Lent ,  Paul W. Wacnik

    IPC分类号： A61N1/34

    CPC分类号： A61N1/36139 ,  A61N1/36057 ,  A61N1/36071

    摘要： Peripheral nerve field stimulation (PNFS) may be controlled based on detected physiological effects of the PNFS, which may be an efferent response to the PNFS. In some examples, a closed-loop therapy system may include a sensing module that senses a physiological parameter of the patient, which may be indicative of the patient's response to the PNFS. Based on a signal generated by the sensing module, the PNFS may be activated, deactivated or modified. Example physiological parameters of the patient include heart rate, respiratory rate, electrodermal activity, muscle activity, blood flow rate, sweat gland activity, pilomotor reflex, or thermal activity of the patient's body. In some examples, a patient pain state may be detected based on a signal generated by the sensing module, and therapy may be controlled based on the detection of the pain state.

    摘要翻译： 可以基于PNFS的检测到的生理效应来控制外周神经区域刺激（PNFS），这可能是对PNFS的传出响应。 在一些示例中，闭环治疗系统可以包括感测患者的生理参数的感测模块，其可以指示患者对PNFS的反应。 基于由感测模块产生的信号，可以激活，去激活或修改PNFS。 患者的生理参数包括心率，呼吸频率，皮肤活动，肌肉活动，血流速度，汗腺活动，引导反射或患者身体的热活动。 在一些示例中，可以基于由感测模块生成的信号来检测患者疼痛状态，并且可以基于疼痛状态的检测来控制治疗。

    Liquid propane gas fuel system
    16.
    发明授权
    Liquid propane gas fuel system 失效
    液态丙烷气体燃料系统

    公开(公告)号：US4492208A

    公开(公告)日：1985-01-08

    申请号：US510112

    申请日：1983-07-01

    申请人： Mark S. Lent

    发明人： Mark S. Lent

    IPC分类号： F02B43/00 ,  F02M21/02

    CPC分类号： F02M21/0239 ,  F02B43/00 ,  F02D19/022 ,  F02M21/0212 ,  F02M21/06 ,  Y02T10/32

    摘要： A liquid propane gas fuel system includes a propane fuel tank. A two stage pressure regulator defined by a housing with a fuel inlet and a fuel outlet is also included. A first fuel conduit extends from an outlet in the fuel tank to the fuel inlet in the pressure regulator. The system supplies fuel to an engine that includes an exhaust gas manifold. A thermoconductive mounting bracket is secured to the housing of the pressure regulator and manifold to transmit heat from the manifold to the regulator in proportion to the load imposed on the engine. A chokeless carburetor is also included in the system and is in fluid communication through a second fuel conduit with the outlet of the pressure regulator. In an alternative embodiment, a heat exchange ris included in the first fuel conduit. In a second alternative embodiment, an electric heating element is positioned within the housing of the pressure regulator.

    摘要翻译： 液体丙烷气体燃料系统包括丙烷燃料箱。 还包括由具有燃料入口和燃料出口的壳体限定的两级压力调节器。 第一燃料管道从燃料箱的出口延伸到压力调节器中的燃料入口。 该系统向包括排气歧管的发动机提供燃料。 导热安装支架固定到压力调节器和歧管的壳体上，以将热量从歧管传递到调节器，与施加在发动机上的负载成比例。 系统中还包括一个无用的化油器，并通过带有压力调节器出口的第二个燃油管道进行流体连通。 在替代实施例中，热交换器包括在第一燃料管道中。 在第二替代实施例中，电加热元件定位在压力调节器的壳体内。

    Incontinence therapy
    17.
    发明授权
    Incontinence therapy 有权
    失禁治疗

    公开(公告)号：US09155885B2

    公开(公告)日：2015-10-13

    申请号：US13265702

    申请日：2010-04-09

    申请人： Xuan K. Wei ,  Eric H. Bonde ,  Keith A. Miesel ,  Mark S. Lent ,  Gregory F. Molnar

    发明人： Xuan K. Wei ,  Eric H. Bonde ,  Keith A. Miesel ,  Mark S. Lent ,  Gregory F. Molnar

    IPC分类号： A61N1/00 ,  A61N1/36 ,  A61N1/372

    CPC分类号： A61N1/36007 ,  A61N1/0514 ,  A61N1/0551 ,  A61N1/36128 ,  A61N1/36135 ,  A61N1/37235 ,  A61N1/37252

    摘要： Techniques for managing urinary or fecal incontinence include delivering a first type of therapy to generate a first physiological response and, upon detecting a trigger event, delivering a second type of therapy to generate a second physiological response. The first type of therapy can be delivered on a substantially regular basis, while the second type of therapy is delivered as needed to provide an additional boost of therapy. The trigger event for activating the delivery of the second type of therapy may include input from a sensor that indicates a bladder condition, patient activity level or patient posture, or patient input. In some examples, the therapy is stimulation therapy.

    摘要翻译： 用于管理尿失禁或大便失禁的技术包括递送第一类型的治疗以产生第一生理反应，并且在检测到触发事件时，递送第二类型的治疗以产生第二生理反应。 第一种类型的治疗可以基本上定期地递送，而第二种类型的治疗根据需要被递送以提供额外的治疗效果。 用于激活第二类治疗的递送的触发事件可以包括来自传感器的输入，其指示膀胱状况，患者活动水平或患者姿势或患者输入。 在一些例子中，治疗是刺激疗法。

    Anti-infective medical device
    18.
    发明授权
    Anti-infective medical device 有权
    抗感染医疗器械

    公开(公告)号：US08691258B2

    公开(公告)日：2014-04-08

    申请号：US11008445

    申请日：2004-12-09

    申请人： Kenneth T. Heruth ,  Christopher M. Hobot ,  William J. Hooper ,  Mark S. Lent ,  Ruchika Singhal ,  Robert M. Skime ,  Randall V. Sparer ,  Maura G. Donovan ,  William J. Bertrand

    发明人： Kenneth T. Heruth ,  Christopher M. Hobot ,  William J. Hooper ,  Mark S. Lent ,  Ruchika Singhal ,  Robert M. Skime ,  Randall V. Sparer ,  Maura G. Donovan ,  William J. Bertrand

    IPC分类号： A61F13/00 ,  A01N25/00

    CPC分类号： A61N1/05 ,  A61N1/0568 ,  A61N1/375

    摘要： Implantable medical devices (IMDS) having anti-infective properties are described. Anti-infective agents are disposed in, on, or about at least a portion of a surface of the medical device. The anti-infective agents are disposed in or on a vehicle, which may be in the form of a coating layer or covering. The vehicle may be biodegradable so that, over time, the anti-infective agent is removed from a tissue location into which the device is implanted, reducing the likelihood that microorganisms resistant to the anti-infective agent will develop. IMDs having an anti-infective agent and an anti-activity agent disposed therein, thereabout, or thereon are also described. The anti-activity agent interferes with the activity of the anti-infective agent, may be released from a surface at the IMD at a time when activity of the anti-infective agent is no longer desired, and may reduce the likelihood that microorganisms resistant to the anti-infective agent will develop.

    摘要翻译： 描述具有抗感染性的植入式医疗装置（IMDS）。 抗感染剂设置在医疗装置的表面的至少一部分上，其上或附近。 抗感染剂设置在车辆中或车辆上，其可以是涂层或覆盖物的形式。 载体可以是可生物降解的，使得随着时间的推移，抗感染剂从植入装置所在的组织位置移除，降低了抗感染剂抗微生物的可能性。 还描述了其上设置有抗感染剂和抗活性剂的IMD，其上或其上。 干扰抗感染剂的活性的抗活性剂可以在不再需要抗感染剂的活性的时候从IMD的表面释放，并且可能降低抗微生物抗性的可能性 抗感染剂会发展。

    Catheters with tracking elements and permeable membranes
    19.
    发明授权
    Catheters with tracking elements and permeable membranes 有权
    导管带跟踪元件和渗透膜

    公开(公告)号：US08246602B2

    公开(公告)日：2012-08-21

    申请号：US10873764

    申请日：2004-06-22

    申请人： Kenneth T. Heruth ,  Mark S. Lent ,  Justin A. Blanco

    发明人： Kenneth T. Heruth ,  Mark S. Lent ,  Justin A. Blanco

    IPC分类号： A61M25/00 ,  A61K9/22

    CPC分类号： A61M25/0043 ,  A61M25/003 ,  A61M25/0105 ,  A61M2025/0057 ,  A61M2025/0166

    摘要： Devices, systems and methods for delivering one or more drugs to one or more internal body locations (such as the cerebrospinal fluid) are disclosed. In various aspects, the systems and methods may involve catheters having infusion sections with permeable membranes and one or more tracking elements that may be used to place the infusions sections on the catheters in selected locations such as the spinal region.

    摘要翻译： 公开了用于将一种或多种药物递送到一个或多个内部身体位置（例如脑脊液）的装置，系统和方法。 在各个方面，系统和方法可以包括具有可渗透膜的输注部分的导管和一个或多个跟踪元件，所述跟踪元件可用于将选定位置（例如脊柱区域）中的输液部分置于导管上。

    Therapy control based on a patient movement state
    20.
    发明授权
    Therapy control based on a patient movement state 有权
    基于患者运动状态的治疗控制

    公开(公告)号：US08121694B2

    公开(公告)日：2012-02-21

    申请号：US12237799

    申请日：2008-09-25

    申请人： Gregory F. Molnar ,  Steven S. Gill ,  Keith A. Miesel ,  Mark S. Lent ,  Timothy J. Denison ,  Eric J. Panken ,  Carl D. Wahlstrand ,  Jonathan C. Werder

    发明人： Gregory F. Molnar ,  Steven S. Gill ,  Keith A. Miesel ,  Mark S. Lent ,  Timothy J. Denison ,  Eric J. Panken ,  Carl D. Wahlstrand ,  Jonathan C. Werder

    IPC分类号： A61N1/18

    CPC分类号： A61B5/04014 ,  A61B5/0006 ,  A61B5/4082 ,  A61B5/6814 ,  A61N1/36003 ,  A61N1/36014 ,  A61N1/36025 ,  A61N1/36067 ,  A61N1/36082

    摘要： A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor.

    摘要翻译： 基于诸如脑电图（EEG）信号的脑信号检测患者的运动状态。 在一些示例中，可以检测指示患者的预期运动的患者的脑的背侧前额叶皮层内的脑信号，以便检测运动状态。 运动状态可以包括指示患者打算启动运动，启动运动，尝试启动运动或实际运动的脑状态。 在一些示例中，在检测到运动状态时，将运动障碍治疗递送给患者。 在一些示例中，在检测到患者不再处于运动状态或患者已成功启动运动时，治疗递送被停用。 此外，在一些示例中，可以基于来自运动传感器的信号来确认基于脑信号检测到的运动状态。