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    CHARACTERIZATION OF REACTION VARIABLES
    11.
    发明申请
    CHARACTERIZATION OF REACTION VARIABLES 审中-公开
    反应变量的表征

    公开(公告)号：US20150377873A9

    公开(公告)日：2015-12-31

    申请号：US14215745

    申请日：2014-03-17

    申请人： Gyros Patent AB

    发明人： Per Andersson ,  Mats Inganas ,  Gunnar Thorsén ,  Gunnar Kylberg

    IPC分类号： G01N33/543

    CPC分类号： G01N33/54306 ,  B01F5/0646 ,  B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01J19/0093 ,  B01J2219/00788 ,  B01J2219/00833 ,  B01J2219/0086 ,  B01J2219/00862 ,  B01J2219/00891 ,  B01L3/5025 ,  B01L3/5027 ,  B01L3/502738 ,  B01L3/502746 ,  B01L2200/06 ,  B01L2200/0605 ,  B01L2200/10 ,  B01L2200/142 ,  B01L2300/069 ,  B01L2300/0803 ,  B01L2300/0806 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/14 ,  B01L2300/16 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0633 ,  B01L2400/0688 ,  B01L2400/086 ,  G01N30/6095 ,  G01N30/7266 ,  G01N33/54366 ,  G01N35/00069 ,  G01N2035/00504 ,  H01J49/04 ,  Y10S435/973

    摘要： A microscale method for the characterization of one or more reaction variables that influence the formation or dissociation of an affinity complex comprising a ligand and a binder, which have mutual affinity for each other. The method is characterized in comprising the steps of: (i) providing a microfluidic device comprising a microchannel structures that are under a common flow control, each microchannel structure comprising a reaction microactivity; (ii) performing essentially in parallel an experiment in each of two or more of the plurality of microchannel structures, the experiment in these two or more microchannel structures comprising either a) formation of an immobilized form of the complex and retaining under flow conditions said form within the reaction microactivity, or b) dissociating, preferably under flow condition, an immobilized form of the complex which has been included in the microfluidic device provided in step (i), at least one reaction variable varies or is uncharacterized for said two or more microchannel structures while the remaining reaction variables are kept essentially constant; (iii) measuring the presentation of the complex in said reaction microactivity in said two or more microchannel structures; and (iv) characterizing said one or more reaction variables based on the values for presentation obtained in step (iii).

    摘要翻译： 用于表征影响包含配体和粘合剂的亲和络合物的形成或解离的一个或多个反应变量的微观方法，其彼此具有相互亲和力。 该方法的特征在于包括以下步骤：（i）提供包含处于共同流量控制下的微通道结构的微流体装置，每个微通道结构包含反应微活性; （ii）在两个或多个多个微通道结构的每一个中基本上并行地进行实验，这两个或更多个微通道结构中的实验包括a）形成复合物的固定形式并在流动条件下保持所述形式 或者b）优选在流动条件下解离包含在步骤（i）中提供的微流体装置中的复合物的固定化形式，至少一个反应变量对于所述两个或更多个变化是变化的或没有表征的 微通道结构，而剩余的反应变量保持基本恒定; （iii）测量所述两个或多个微通道结构中所述反应微活性物中复合物的表现; 和（iv）基于在步骤（iii）中获得的呈现值来表征所述一个或多个反应变量。

    CHARACTERIZATION OF REACTION VARIABLES
    12.
    发明申请
    CHARACTERIZATION OF REACTION VARIABLES 审中-公开
    反应变量的表征

    公开(公告)号：US20140199783A1

    公开(公告)日：2014-07-17

    申请号：US14215745

    申请日：2014-03-17

    申请人： Gyros Patent AB

    发明人： Per Andersson ,  Mats Inganas ,  Gunnar Thorsén ,  Gunnar Kylberg

    IPC分类号： G01N33/543

    CPC分类号： G01N33/54306 ,  B01F5/0646 ,  B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01J19/0093 ,  B01J2219/00788 ,  B01J2219/00833 ,  B01J2219/0086 ,  B01J2219/00862 ,  B01J2219/00891 ,  B01L3/5025 ,  B01L3/5027 ,  B01L3/502738 ,  B01L3/502746 ,  B01L2200/06 ,  B01L2200/0605 ,  B01L2200/10 ,  B01L2200/142 ,  B01L2300/069 ,  B01L2300/0803 ,  B01L2300/0806 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/14 ,  B01L2300/16 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0633 ,  B01L2400/0688 ,  B01L2400/086 ,  G01N30/6095 ,  G01N30/7266 ,  G01N33/54366 ,  G01N35/00069 ,  G01N2035/00504 ,  H01J49/04 ,  Y10S435/973

    摘要： A microscale method for the characterization of one or more reaction variables that influence the formation or dissociation of an affinity complex comprising a ligand and a binder, which have mutual affinity for each other. The method is characterized in comprising the steps of: (i) providing a microfluidic device comprising a microchannel structures that are under a common flow control, each microchannel structure comprising a reaction microactivity; (ii) performing essentially in parallel an experiment in each of two or more of the plurality of microchannel structures, the experiment in these two or more microchannel structures comprising either a) formation of an immobilized form of the complex and retaining under flow conditions said form within the reaction microactivity, or b) dissociating, preferably under flow condition, an immobilized form of the complex which has been included in the microfluidic device provided in step (i), at least one reaction variable varies or is uncharacterized for said two or more microchannel structures while the remaining reaction variables are kept essentially constant; (iii) measuring the presentation of the complex in said reaction microactivity in said two or more microchannel structures; and (iv) characterizing said one or more reaction variables based on the values for presentation obtained in step (iii).

    摘要翻译： 用于表征影响包含配体和粘合剂的亲和络合物的形成或解离的一个或多个反应变量的微观方法，其彼此具有相互亲和力。 该方法的特征在于包括以下步骤：（i）提供包含处于共同流量控制下的微通道结构的微流体装置，每个微通道结构包含反应微活性; （ii）在两个或更多个微通道结构的每一个中基本上并行地进行实验，这两个或更多个微通道结构中的实验包括a）形成固定化形式的复合物并在流动条件下保留所述形式 或者b）优选在流动条件下解离已经包含在步骤（i）中提供的微流体装置中的复合物的固定形式，至少一个反应变量对于所述两个或更多个变化是变化的或没有表征的 微通道结构，而剩余的反应变量保持基本恒定; （iii）测量所述两个或多个微通道结构中所述反应微活性物中复合物的表现; 和（iv）基于在步骤（iii）中获得的呈现值来表征所述一个或多个反应变量。

    LID
    14.
    发明申请
    LID 审中-公开
    盖

    公开(公告)号：US20100068099A1

    公开(公告)日：2010-03-18

    申请号：US12513421

    申请日：2007-11-08

    申请人： Johan Engström

    发明人： Johan Engström

    IPC分类号： B01L3/00

    CPC分类号： B01L3/502707 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/041 ,  B01L2300/0803

    摘要： An aspect of the present invention includes a microfluidic assembly comprising: a planar substrate, a least a first surface of which has at least one open microchannel structure, a lid forming sheet material attached with a first surface to said first surface of said planar substrate, said lid forming sheet material is covering at least a portion of said at least one microchannel structure, wherein said lid forming sheet material has a first region with a first rigidity and a second region with a second rigidity. Other aspects of the present invention are reflected in the detailed description, figures and claims.

    摘要翻译： 本发明的一个方面包括一种微流体组件，其包括：平面基板，其至少第一表面具有至少一个开放的微通道结构，附接有所述平面基板的所述第一表面的第一表面的盖形成板材料， 所述盖形成片材覆盖所述至少一个微通道结构的至少一部分，其中所述盖形成片材具有具有第一刚度的第一区域和具有第二刚度的第二区域。 本发明的其它方面在详细描述，附图和权利要求中被体现。

    SPINNER HOME SEQUENCE
    15.
    发明申请
    SPINNER HOME SEQUENCE 有权
    旋转式家庭系列

    公开(公告)号：US20090308470A1

    公开(公告)日：2009-12-17

    申请号：US11916012

    申请日：2006-05-31

    申请人： Mårten Bergström ,  Robert Bielik ,  Tobias Söderman ,  Agneta Ohlström

    发明人： Mårten Bergström ,  Robert Bielik ,  Tobias Söderman ,  Agneta Ohlström

    IPC分类号： F17D3/00 ,  G01B11/14

    CPC分类号： G01N35/00732 ,  B01L3/5027 ,  B01L2200/025 ,  B01L2300/021 ,  B01L2300/0806 ,  G01N35/1011 ,  G01N2035/1034 ,  Y10T137/86389

    摘要： The present invention relates to a method for determining the identity of a microfluidic device and a home position by means of a set of home position marks on the microfluidic device, which is of the type used in a microfluidic system. Said method comprises following phases: a microfluidic device scanning phase, wherein a microfluidic device is scanned for mark identifiers; a microfluidic device identifying phase, wherein at least one a characteristic feature of the set of home marks is/are determined and used for identifying the identity of the microfluidic device; a home position determining phase, wherein the home position is determined by the use of at least a subset of the home position marks identified during said previous phases. The present invention relates to a set of home marks, a microfluidic device carrying such a set of home marks, a microfluidic system, a computer program product and a computer program on a computer usable medium.

    摘要翻译： 本发明涉及一种通过微流体装置上的一组原始位置标记来确定微流体装置和原始位置的身份的方法，其是在微流体系统中使用的类型。 所述方法包括以下阶段：微流体装置扫描阶段，其中扫描微流体装置用于标记识别符; 微流体装置识别阶段，其中确定并且使用该组归属标记中的至少一个特征特征来识别微流体装置的身份; 原始位置确定阶段，其中通过使用在所述先前阶段期间识别的原始位置标记的至少一个子集来确定原始位置。 本发明涉及一套家用商标，一种在这种计算机可用介质上携带这样的家庭标记的微流体装置，微流体系统，计算机程序产品和计算机程序。

    Matrix and method of producing said matrix
    18.
    发明授权
    Matrix and method of producing said matrix 有权
    矩阵和产生所述矩阵的方法

    公开(公告)号：US07182890B2

    公开(公告)日：2007-02-27

    申请号：US11001830

    申请日：2004-12-02

    申请人： Per Ove Öhman ,  Lars Rune Lundbladh

    发明人： Per Ove Öhman ,  Lars Rune Lundbladh

    IPC分类号： B29C33/38 ,  B29C33/42

    CPC分类号： B29C33/565 ,  B29C33/02 ,  B29C33/424 ,  B29C45/2632 ,  B29C2045/2634 ,  B29L2017/005 ,  G11B7/263 ,  Y10S425/81

    摘要： The invention relates to a matrix suitable for use in the replication of a plastic element having a positive microstructure, comprising a first wear-resistant layer that is supported by a carrier element, wherein the matrix comprises a heating means for supplying electrical heat energy through the wear-resistant layer or carrier element. The invention further relates to a plastic element producing machine and a method for the manufacture of a plastic element having a surface with a positive microstructure.

    摘要翻译： 本发明涉及一种适用于复制具有正微观结构的塑料元件的基体，其包括由载体元件支撑的第一耐磨层，其中所述基体包括用于通过所述载体元件提供电热能的加热装置 耐磨层或载体元件。 本发明还涉及一种塑料元件生产机器和一种用于制造具有正微结构的表面的塑料元件的方法。