公开(公告)号：US20030033102A1

公开(公告)日：2003-02-13

申请号：US10149779

申请日：2002-06-12

Inventor： Thomas Dietiker

IPC: G01D018/00

CPC classification number: A61B5/14546 ,  A61B5/14532 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/1495 ,  G01J1/08 ,  G01J9/00 ,  G01J2003/2866 ,  G01N21/274 ,  G01N21/35 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/3577 ,  G01N2021/3144 ,  G01N2201/1211 ,  G01N2201/12723 ,  H01L27/14647 ,  H01L31/03529

Abstract: A non-invasive emitter-photodiode sensor which is able to provide a data-stream corresponding to the actual wavelength of light emitted thereby allowing calibration of the sensor signal processing equipment and resulting in accurate measurements over a wider variation in emitter wavelength ranges.

Abstract translation: 能够提供对应于由此发射的光的实际波长的数据流的非侵入式发射极 - 光电二极管传感器允许对传感器信号处理设备进行校准，并且在发射器波长范围的更宽的变化范围内得到准确的测量。

公开(公告)号：US5246858A

公开(公告)日：1993-09-21

申请号：US661810

申请日：1991-02-27

Applicant: Steven R. Arbuckle ,  William R. Boyd ,  Michael E. Grant ,  Mark A. Gregory ,  Russell T. Gray ,  Friedrich Jost ,  Daniel L. Kennedy ,  Dino Perin ,  Richard Riedel ,  David E. Storvick ,  John W. Stoughton

Inventor： Steven R. Arbuckle ,  William R. Boyd ,  Michael E. Grant ,  Mark A. Gregory ,  Russell T. Gray ,  Friedrich Jost ,  Daniel L. Kennedy ,  Dino Perin ,  Richard Riedel ,  David E. Storvick ,  John W. Stoughton

IPC: G01N21/47 ,  G01N21/77 ,  G01N21/86 ,  G01N33/52

CPC classification number: G01N21/8483 ,  G01N2021/478 ,  G01N2201/1214 ,  G01N2201/122 ,  G01N2201/12723 ,  Y10T436/10

Abstract: A method and apparatus (10) for determining the remission of a chemistry (106) which reacts with a medically significant component of a body fluid. The remission of the chemistry (106) changes as it reacts. The method and apparatus (10) include irradiating the chemistry (106) with a radiation source (182), detecting remissions of radiation from the chemistry (106) with a radiation detector (300), providing a radiation pathway (164) between the source (182) and the chemistry (106), providing a remission pathway (164) between the chemistry (106) and the detector (300), and detecting the rate of change of remission of the chemistry (106) with respect to time. The irradiating, detecting and rate detecting steps and apparatus comprise initially irradiating the chemistry (106) at a first time rate and detecting remissions therefrom, comparing remission data from remission readings spaced apart by a first number of intervening remission readings, and determining when the difference between compared readings exceeds a first predetermined limit. The time rate of irradiation of the chemistry is changed once the difference between compared readings exceeds the first limit. Remission data from remission readings spaced apart by a second number of intervening remission readings are then compared. The method and apparatus next determine when the difference between compared readings no longer exceeds a second predetermined limit. The last remission reading is then converted to the concentration of the medically significant component of the body fluid.

Abstract translation: 一种用于确定化学物质（106）的缓解的方法和装置（10），其与体液的医学上重要的组分反应。 化学物质（106）的缓解随着反应而发生变化。 该方法和装置（10）包括用辐射源（182）照射化学物质（106），用辐射检测器（300）检测来自化学物质（106）的辐射的放射，提供源之间的辐射通路（164） （106）和化学物质（106），在化学物质（106）和检测器（300）之间提供缓释途径（164），以及检测化学物质（106）相对于时间的缓解变化率。 照射，检测和速率检测步骤和装置包括首先以第一时间速率辐射化学物质（106）并检测其中的缓解，将缓释数据与间隔开的缓冲读数与第一数量的介入缓解读数进行比较，以及确定何时差异 比较读数超过第一预定极限。 一旦比较读数之间的差超过第一限制，化学物质的照射时间变化就会改变。 然后比较缓冲读数与间隔第二数量的介入缓解读数的缓解数据。 该方法和装置接下来确定比较读数之间的差异何时不再超过第二预定极限。 然后将最后的缓解读数转化为体液的医学重要组分的浓度。

公开(公告)号：US4578762A

公开(公告)日：1986-03-25

申请号：US509920

申请日：1983-07-01

Applicant: Jacob Y. Wong

Inventor： Jacob Y. Wong

IPC: G01J1/36 ,  G01N21/27 ,  G01N21/35 ,  G01N33/00 ,  G06F17/40 ,  G06F15/46

CPC classification number: G01J1/36 ,  G01N21/274 ,  G01N33/0006 ,  G01N21/3504 ,  G01N2201/12723

Abstract: A carbon dioxide analyzer for medical purposes is rendered self-calibrating by continuously measuring pairs of two or three each of several components as follows:1st pair: vacuum cell, open hole and sample cell reference cell, open hole and sample cell2nd pair: vacuum cell, standard cell reference cell, standard cell3rd pair: vacuum cell, open hole reference cell, open hole4th pair: vacuum cell, standard cell, sample cell reference cell, standard cell, sample cellThe ratios of these measurement pairs are treated mathematically in a computer or microprocessor to obtain a reading for CO.sub.2 and to correct other readings and to monitor the integrity of the standard cell. A novel two-wheel chopper and mirror arrangement facilitates the measurements.

Abstract translation: 用于医疗目的的二氧化碳分析仪通过连续地测量几个组分中的两个或三个对的对来进行自校准，如下所述：第一对：真空室，开孔和样品池参比池，开孔和样品池第二对：真空 细胞，标准细胞参考细胞，标准细胞第3对：真空细胞，露天参照细胞，开孔第4对：真空细胞，标准细胞，样品细胞参比细胞，标准细胞，样品细胞这些测定对的比例用数学方法处理 在计算机或微处理器中获得二氧化碳的读数并校正其他读数并监测标准单元的完整性。 一种新颖的两轮斩波器和镜子布置便于测量。

公开(公告)号：US3581085A

公开(公告)日：1971-05-25

申请号：US3581085D

申请日：1968-05-20

Applicant: SONJA I BARRETT

Inventor： BARRETT SONJA I

IPC: G01N21/64 ,  G01N33/18 ,  G01N21/26

CPC classification number: G01N33/1833 ,  G01N21/64 ,  G01N2201/12723 ,  Y02A20/206 ,  Y10T137/2496 ,  Y10T137/8158

Abstract: A continuous monitoring system for measuring the oil content of discharged ballast water based on the use of an ultraviolet fluorescence meter. The meter operates by passing ultraviolet light through a sample jet of water, the fluorescent visible light being measured by a filter-photocell combination angled to the incident beam. At elevated oil concentrations, the meter response diminishes as both ultraviolet and visible light are cut off by the increasing amounts of dark oil present, thus giving a false reading. A photocell or fluorescent indicator screen is therefore proposed as a warning device to be used in conjunction with the above monitoring system, to indicate when the emerging ultraviolet light is obscured by excess quantities of oil.

公开(公告)号：US20230204497A1

公开(公告)日：2023-06-29

申请号：US18111740

申请日：2023-02-20

Applicant: Apple Inc.

Inventor： Miikka M. Kangas ,  Mark Alan Arbore ,  David I. Simon ,  Michael J. Bishop ,  James W. Hillendahl ,  Robert Chen

IPC: G01N21/27 ,  G01N21/35 ,  G01N21/47 ,  G01J3/32 ,  G01J3/36 ,  G01J3/433 ,  G01J3/447 ,  G01J3/02 ,  G01J3/42

CPC classification number: G01N21/276 ,  G01N21/35 ,  G01N21/474 ,  G01N21/4785 ,  G01J3/32 ,  G01J3/36 ,  G01J3/433 ,  G01J3/447 ,  G01J3/0286 ,  G01J3/42 ,  G01N2021/4709 ,  G01N2201/0221 ,  G01N2201/12723 ,  G01N21/49

Abstract: This relates to systems and methods for measuring a concentration and type of substance in a sample at a sampling interface. The systems can include a light source, optics, one or more modulators, a reference, a detector, and a controller. The systems and methods disclosed can be capable of accounting for drift originating from the light source, one or more optics, and the detector by sharing one or more components between different measurement light paths. Additionally, the systems can be capable of differentiating between different types of drift and eliminating erroneous measurements due to stray light with the placement of one or more modulators between the light source and the sample or reference. Furthermore, the systems can be capable of detecting the substance along various locations and depths within the sample by mapping a detector pixel and a microoptics to the location and depth in the sample.

公开(公告)号：US20180313690A1

公开(公告)日：2018-11-01

申请号：US15937177

申请日：2018-03-27

Applicant: VIAVI Solutions Inc.

Inventor： Curtis R. HRUSKA

IPC: G01J3/02 ,  G01J3/42 ,  G01J3/10

CPC classification number: G01J3/0297 ,  G01J3/0205 ,  G01J3/027 ,  G01J3/10 ,  G01J3/42 ,  G01N21/274 ,  G01N2201/12707 ,  G01N2201/12715 ,  G01N2201/12723 ,  G01N2201/1273 ,  G01N2201/12738

Abstract: A device may determine a calibration value for a spectrometer using light from a first light source; deactivate the first light source after determining the calibration value; perform measurement with regard to a sample based on the calibration value, wherein the measurement of the sample is performed using light from a second light source; determine that the calibration value is to be updated; and update the calibration value using the light from the first light source.

公开(公告)号：US20180231457A1

公开(公告)日：2018-08-16

申请号：US15751454

申请日：2016-08-29

Applicant: APPLE INC.

Inventor： Robert CHEN ,  Trent D. RIDDER ,  Miikka M. KANGAS ,  David I. SIMON ,  Matthew A. TERREL

IPC: G01N21/27 ,  G01N21/31

CPC classification number: G01N21/274 ,  G01N21/31 ,  G01N2201/124 ,  G01N2201/12723 ,  G01N2201/12776

Abstract: Methods and systems for measurement time distribution for referencing schemes are disclosed. The disclosed methods and systems can be capable of dynamically changing the measurement time distribution based on the sample signal, reference signal, noise levels, and SNR. The methods and systems can be configured with a plurality of measurement states, including a sample measurement state, reference measurement state, and dark measurement state. In some examples, the measurement time distribution scheme can be based on the operating wavelength, the measurement location at the sampling interface, and/or targeted SNR. Examples of the disclosure further include systems and methods for measuring the different measurement states concurrently. Moreover, the systems and methods can include a high-frequency detector to eliminate or reduce decorrelated noise fluctuations that can lower the SNR.

公开(公告)号：US09632022B2

公开(公告)日：2017-04-25

申请号：US14382334

申请日：2013-03-05

Applicant: BIOSURFIT S.A.

Inventor： Joao Manuel De Oliveira Garcia Da Fonseca

IPC: G01N21/41 ,  G01N21/552

CPC classification number: G01N33/54373 ,  G01N21/41 ,  G01N21/553 ,  G01N33/54346 ,  G01N33/553 ,  G01N2201/0612 ,  G01N2201/06146 ,  G01N2201/0621 ,  G01N2201/0635 ,  G01N2201/12723

Abstract: The disclosure relates to processing SPR signals, in particular signals obtained by illuminating a conductive surface with light at two wavelengths. Processing SPR signals can involve processing a first and second signal indicative of an intensity of light, received from a conductive layer at which SPR has occurred, as a function of angle of incidence, reflection or diffraction at the layer. The first and second signals each have two dips corresponding to a respective wavelength of the light at a respective angle at which surface plasmon resonance occurs for the respective wavelength and a peak between the two dips. The processing includes deriving a first and second value of a quantity indicative of signal magnitudes in the region of the peak. The first and second values can be compared to detect a change in refractive index at the layer after the first signal and before the second signal was captured.

公开(公告)号：US20150355051A1

公开(公告)日：2015-12-10

申请号：US14827935

申请日：2015-08-17

Applicant: Songping Gao

Inventor： Songping Gao

IPC: G01M11/00 ,  G01N21/64 ,  G01J1/58

CPC classification number: G01M11/00 ,  G01J1/58 ,  G01N21/64 ,  G01N21/6428 ,  G01N21/6486 ,  G01N2021/6439 ,  G01N2201/06113 ,  G01N2201/12723

Abstract: An optical system includes a sample carrier receiving region configured to receive a sample carrier carrying a sample for processing, a source that emits an excitation signal having a wavelength within a first predetermined wavelength range, and a first set of optical components that direct the excitation signal along an excitation path to the sample carrier receiving region, wherein radiation having a wavelength within a second predetermined wavelength range is emitted from the sample carrier receiving region in response to receiving the excitation signal. The optical system further includes a detector configured to detect the emitted radiation and generates a signal indicative of a power of the detected radiation and a second set of optical components that directs the emitted radiation along a collection path to the detector. The optical system further includes a power meter that measures a power of the radiation emitted from the sample carrier receiving region and generates a signal indicative thereof.

Abstract translation: 光学系统包括：样本载波接收区域，被配置为接收承载用于处理的样本的采样载体;发射具有在第一预定波长范围内的波长的激励信号的源;以及引导激励信号的第一组光学部件 沿着到样品载体接收区域的激励路径，其中响应于接收到激发信号，从采样载体接收区域发射具有第二预定波长范围内的波长的辐射。 光学系统还包括检测器，其被配置为检测所发射的辐射并产生指示检测到的辐射的功率的信号;以及第二组光学部件，其将发射的辐射沿着收集路径引导到检测器。 光学系统还包括功率计，其测量从采样载体接收区域发射的辐射的功率，并产生指示其的信号。

公开(公告)号：US20150346085A1

公开(公告)日：2015-12-03

申请号：US14648855

申请日：2013-12-04

Applicant: SP3H

Inventor： Sylvain OBERTI ,  Johan FOURNEL

IPC: G01N21/27 ,  G01N21/3504

CPC classification number: G01N21/3577 ,  G01N21/274 ,  G01N21/3504 ,  G01N2021/3181 ,  G01N2201/062 ,  G01N2201/0624 ,  G01N2201/121 ,  G01N2201/1211 ,  G01N2201/124 ,  G01N2201/1242 ,  G01N2201/1247 ,  G01N2201/127 ,  G01N2201/12723

Abstract: A method for controlling a spectrometer for analyzing a product includes steps of: acquiring a measurement representative of the operation of a light source, determining, depending on the measurement, a value of supply current of the light source, and/or a value of integration time of light-sensitive cells of a sensor, disposed on a route of a light beam emitted by the light source and having interacted with a product to be analyzed, and if the integration time and/or supply current value is between threshold values, supplying the light source with a supply current corresponding to the determined supply current value, adjusting the integration time of a light-sensitive cell to the determined integration time value, and acquiring light intensity measurements supplied by the sensor, enabling a spectrum to be formed.

Abstract translation: 一种用于控制用于分析产品的光谱仪的方法包括以下步骤：获取代表光源的操作的测量，根据测量确定光源的电源电流的值和/或积分值 传感器的感光单元的时间设置在由光源发射的光束的路径上并且与待分析的产品相互作用，并且如果积分时间和/或电源电流值在阈值之间，则提供 所述光源具有与所确定的电源电流值相对应的电源电流，将感光单元的积分时间调整到所确定的积分时间值，以及获取由所述传感器提供的光强度测量值，从而能够形成光谱。