公开(公告)号：US07153519B2

公开(公告)日：2006-12-26

申请号：US10607247

申请日：2003-06-25

申请人： Jeffrey A. Hubbell ,  Chandrashekhar P. Pathak ,  Amarpreet S. Sawhney ,  Neil P. Desai ,  Jennifer L. Hill ,  Syed F. A. Hossainy

发明人： Jeffrey A. Hubbell ,  Chandrashekhar P. Pathak ,  Amarpreet S. Sawhney ,  Neil P. Desai ,  Jennifer L. Hill ,  Syed F. A. Hossainy

IPC分类号： A61F2/00 ,  C12N11/04 ,  A61K38/00 ,  A61K9/14 ,  A61K31/74

CPC分类号： C12N11/04 ,  A61K9/1635 ,  A61K9/1647 ,  A61K9/5026 ,  A61K9/5031 ,  A61K9/5073 ,  A61K38/42 ,  A61K38/44 ,  A61K47/645 ,  A61K47/6903 ,  A61K47/6927 ,  A61K2035/128 ,  A61L24/0031 ,  A61L24/0042 ,  A61L24/046 ,  A61L26/0019 ,  A61L27/34 ,  A61L27/3683 ,  A61L27/38 ,  A61L27/52 ,  A61L29/085 ,  A61L31/10 ,  A61L31/145 ,  A61L31/148 ,  B82Y5/00 ,  C08B37/003 ,  C08B37/0072 ,  C08B37/0084 ,  C08F290/00 ,  C08F290/02 ,  C08F290/06 ,  C08F290/062 ,  C08F290/08 ,  C08F290/10 ,  C08F291/00 ,  C09D153/00 ,  C12N5/0012 ,  C12N5/0677 ,  C12N2533/30 ,  C12N2533/32 ,  C12N2533/40 ,  C12N2533/74 ,  Y10S514/801 ,  Y10S530/812 ,  Y10S530/813 ,  Y10S530/815 ,  Y10S530/817 ,  Y10T428/2987 ,  Y10T428/2989 ,  C08L71/02

摘要： Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particularly useful as tissue adhesives, coatings for tissue lumens including blood vessels, coatings for cells such as islets of Langerhans, coatings, plugs, supports or substrates for contact with biological materials such as the body, and as drug delivery devices for biologically active molecules.

摘要翻译： 通过添加可自由基聚合的基团（例如含有碳 - 碳双键或三键的那些基团）来修饰水溶性大分子单体，其可在温和条件下聚合以包封组织，细胞或生物活性材料。 聚合物材料特别可用作组织粘合剂，用于包括血管的组织腔的涂层，用于细胞的涂层，例如朗格汉斯岛，涂层，塞子，用于与生物材料例如身体接触的支撑体或基底，以及作为用于 生物活性分子。

公开(公告)号：US20050131130A1

公开(公告)日：2005-06-16

申请号：US10990159

申请日：2004-11-15

申请人： Akihiro Kitamura

发明人： Akihiro Kitamura

IPC分类号： B05D7/02 ,  B05D7/24 ,  B29C45/14 ,  B29C45/16 ,  C08F290/08 ,  C08K3/00 ,  C09D4/02 ,  C09D123/26 ,  C09D151/06

CPC分类号： C08F290/08 ,  B29C45/1679

摘要： An object of the present invention is to provide a paint composition for in-mold coating of thermoplastic plastic substrates, the paint film resultant from which composition neither peels off nor becomes turbid even if the mold is opened in a state where its temperature is high, needless to say that the resultant paint film has excellent adhesion to nonpolar thermoplastic plastic substrates and adequate flowability. As a means of achieving this object, a paint composition according to the present invention for in-mold coating of thermoplastic plastic substrates comprises: an acryl-modified unsaturated dicarboxylic acid (anhydride)-grafted polyolefin (A); at least one member (B) selected from the group consisting of reactive oligomers and reactive monomers; and a radical polymerization initiator (C); in a specific formulation ratio, with the paint composition being characterized in that: the acryl-modified unsaturated dicarboxylic acid (anhydride)-grafted polyolefin (A) is in the range of 92 to 112° C. in melting point and in the range of 5 to 15 mass % in ratio for which unsaturated dicarboxylic acid (anhydride)-derived structural units account in its structure.

摘要翻译： 本发明的目的是提供一种热塑性塑料基材的模内涂布用涂料组合物，即使在其温度高的状态下打开模具，组合物也不会剥离或变得混浊的涂膜组合物， 不用说，所得的漆膜对非极性热塑性塑料基材具有优异的粘附性和足够的流动性。 作为实现该目的的手段，本发明的用于模内涂布热塑性塑料基材的涂料组合物包括：丙烯酸改性的不饱和二羧酸（酸酐）接枝的聚烯烃（A）; 至少一种选自反应性低聚物和反应性单体的成员（B）; 和自由基聚合引发剂（C）; 在具体的配方比例下，涂料组合物的特征在于：丙烯酸改性的不饱和二羧酸（酸酐）接枝的聚烯烃（A）的熔点在92-112℃的范围内 不饱和二羧酸（酸酐）衍生结构单元占其结构的比例为5〜15质量％。

公开(公告)号：US06673875B2

公开(公告)日：2004-01-06

申请号：US10169607

申请日：2002-07-03

申请人： Shabbir Attarwala ,  Richard D. Rich ,  Natalie R. Li

发明人： Shabbir Attarwala ,  Richard D. Rich ,  Natalie R. Li

IPC分类号： C09J400

CPC分类号： C09J4/06 ,  C08F290/067 ,  C08F290/08

摘要： An anaerobic adhesive composition having enhanced toughness and resistance to crack propagation, particularly subsequent to thermal exposure, comprising a combination of three monomers consisting of (a) at least one (meth) acrylate monomer, (b) at least one (meth)acrylate-terminated urethane modified acrylonitrile/butadiene prepolymer, and (c) at least one (meth)acrylate-terminated acrylic/polyisocyanate adduct.

摘要翻译： 一种厌氧粘合剂组合物，其具有增强的韧性和抗裂纹扩展性，特别是在热暴露后，包括由（a）至少一种（甲基）丙烯酸酯单体组成的三种单体，（b）至少一种（甲基）丙烯酸酯 - 封端的氨基甲酸酯改性丙烯腈/丁二烯预聚物，和（c）至少一种（甲基）丙烯酸酯封端的丙烯酸/多异氰酸酯加合物。

公开(公告)号：US06632446B1

公开(公告)日：2003-10-14

申请号：US09694836

申请日：2000-10-23

申请人： Jeffrey A. Hubbell ,  Chandrashekhar P. Pathak ,  Amarpreet S. Sawhney ,  Neil P. Desai ,  Jennifer L. Hill ,  Syed F. A. Hossainy

发明人： Jeffrey A. Hubbell ,  Chandrashekhar P. Pathak ,  Amarpreet S. Sawhney ,  Neil P. Desai ,  Jennifer L. Hill ,  Syed F. A. Hossainy

IPC分类号： A61F200

CPC分类号： C12N11/04 ,  A61K9/1635 ,  A61K9/1647 ,  A61K9/5026 ,  A61K9/5031 ,  A61K9/5073 ,  A61K38/42 ,  A61K38/44 ,  A61K47/645 ,  A61K47/6903 ,  A61K47/6927 ,  A61K2035/128 ,  A61L24/0031 ,  A61L24/0042 ,  A61L24/046 ,  A61L26/0019 ,  A61L27/34 ,  A61L27/3683 ,  A61L27/38 ,  A61L27/52 ,  A61L29/085 ,  A61L31/10 ,  A61L31/145 ,  A61L31/148 ,  B82Y5/00 ,  C08B37/003 ,  C08B37/0072 ,  C08B37/0084 ,  C08F290/00 ,  C08F290/02 ,  C08F290/06 ,  C08F290/062 ,  C08F290/08 ,  C08F290/10 ,  C08F291/00 ,  C09D153/00 ,  C12N5/0012 ,  C12N5/0677 ,  C12N2533/30 ,  C12N2533/32 ,  C12N2533/40 ,  C12N2533/74 ,  Y10S514/801 ,  Y10S530/812 ,  Y10S530/813 ,  Y10S530/815 ,  Y10S530/817 ,  Y10T428/2987 ,  Y10T428/2989 ,  C08L71/02

摘要： Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particularly useful as tissue adhesives, coatings for tissue lumens including blood vessels, coatings for cells such as islets of Langerhans, and coatings, plugs, supports or substrates for contact with biological materials such as the body, and as drug delivery devices for biologically active molecules. A medical condition can be treated by applying to a site a polymerization initiator, then applying a substantially water-soluble, degradable macromer of at least 200 mw and having at least two crosslinkable substituents, and polymerizing the macromer to form a polymeric material that can adhere two surfaces together, be an immunoisolation barrier, prevent adhesion of the site to another surface, or contain a biologically active material for delivery or to provide the polymeric material with resistance to bacterial growth or a decrease in inflammatory response. A biocompatible substrate can be coated by applying a mixture of the macromer of at least 400 mw and an initiator and polymerizing. The initiator may be applied to the substrate before the macromer.

摘要翻译： 通过添加可自由基聚合的基团（例如含有碳 - 碳双键或三键的那些基团）来修饰水溶性大分子单体，其可以在温和条件下聚合以包封组织，细胞或生物活性材料。 聚合物材料特别可用作组织粘合剂，包括血管的组织腔的涂层，诸如朗格汉斯岛的细胞的涂层，以及用于与生物材料如身体接触的涂层，塞子，支撑体或基底，以及作为药物递送装置 用于生物活性分子。 可以通过将聚合引发剂施用到位点，然后施加至少200mw的基本上水溶性的可降解的大分子单体并且具有至少两个可交联取代基来进行处理，并聚合大分子单体以形成可粘附的聚合物材料 两个表面在一起，是免疫隔离屏障，防止部位粘附到另一个表面，或含有用于递送的生物活性材料或提供抗细菌生长或炎性反应降低的聚合材料。 通过施加至少400mw的大分子单体和引发剂的混合物并进行聚合，可以涂覆生物相容的底物。 引发剂可以在大分子单体之前施加到基材上

公开(公告)号：US06465001B1

公开(公告)日：2002-10-15

申请号：US09033871

申请日：1998-03-03

申请人： Jeffrey A. Hubbell ,  Chandrashekhar P. Pathak ,  Amarpreet Sawhney ,  Neil Desai ,  Syed Hossainy ,  Jennifer L. Hill-West

发明人： Jeffrey A. Hubbell ,  Chandrashekhar P. Pathak ,  Amarpreet Sawhney ,  Neil Desai ,  Syed Hossainy ,  Jennifer L. Hill-West

IPC分类号： A61F200

CPC分类号： C12N11/04 ,  A61K9/1635 ,  A61K9/1647 ,  A61K9/5026 ,  A61K9/5031 ,  A61K9/5073 ,  A61K38/42 ,  A61K38/44 ,  A61K47/645 ,  A61K47/6903 ,  A61K47/6927 ,  A61K2035/128 ,  A61L24/0031 ,  A61L24/0042 ,  A61L24/046 ,  A61L26/0019 ,  A61L27/34 ,  A61L27/3683 ,  A61L27/38 ,  A61L27/52 ,  A61L29/085 ,  A61L31/10 ,  A61L31/145 ,  A61L31/148 ,  B82Y5/00 ,  C08B37/003 ,  C08B37/0072 ,  C08B37/0084 ,  C08F290/00 ,  C08F290/02 ,  C08F290/06 ,  C08F290/062 ,  C08F290/08 ,  C08F290/10 ,  C08F291/00 ,  C09D153/00 ,  C12N5/0012 ,  C12N5/0677 ,  C12N2533/30 ,  C12N2533/32 ,  C12N2533/40 ,  C12N2533/74 ,  Y10S514/801 ,  Y10S530/812 ,  Y10S530/813 ,  Y10S530/815 ,  Y10S530/817 ,  Y10T428/2987 ,  Y10T428/2989 ,  C08L71/02

摘要： Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particularly useful as tissue adhesives, coatings for tissue lumens including blood vessels, coatings for cells such as islets of Langerhans, and coatings, plugs, supports or substrates for contact with biological materials such as the body, and as drug delivery devices for biologically active molecules. A medical condition at a localized site is treated by applying a polymerization initiator and then applying a substantially water-soluble, degradable macromer of at least 200 mw and having at least two crosslinkable substituents, and polymerizing the macromer to form a crosslinked polymeric material at the site. The crosslinked polymeric material may adhere two surfaces together, or be a barrier that provides immunoisolation or prevents adhesion of the site to another surface such as post-surgical adhesion. A biologically active material may be present when the macromer is polymerized to provide for delivery of the biologically active material, or to provide the polymeric material with a desired property such as resistance to bacterial growth or a decrease in inflammatory response.

摘要翻译： 通过添加可自由基聚合的基团（例如含有碳 - 碳双键或三键的那些基团）来修饰水溶性大分子单体，其可在温和条件下聚合以包封组织，细胞或生物活性材料。 聚合物材料特别可用作组织粘合剂，包括血管的组织腔的涂层，诸如朗格汉斯岛的细胞的涂层，以及用于与生物材料如身体接触的涂层，塞子，支撑体或基底，以及作为药物递送装置 用于生物活性分子。 通过施加聚合引发剂然后施加至少200mw的基本上水溶性的可降解的大分子单体并且具有至少两个可交联取代基来处理局部位点处的医学状况，并聚合大分子单体以形成交联的聚合物材料 现场。 交联的聚合物材料可以将两个表面粘合在一起，或者是提供免疫隔离或防止位点粘附到另一表面的屏障，例如手术后粘连。 当大分子单体聚合以提供生物活性材料的递送时，或者为聚合物材料提供所需性质，例如耐细菌生长或炎症反应降低时，可存在生物活性物质。

公开(公告)号：US20020004537A1

公开(公告)日：2002-01-10

申请号：US09073863

申请日：1998-05-07

发明人： VADIM V. KRONGAUZ ,  CHAU T.M. HA ,  SANGEETA RAMPURIA

IPC分类号： C08J003/28

CPC分类号： H01B3/30 ,  C08F290/147 ,  C09D4/06 ,  C09J4/06 ,  G11B7/26 ,  C08F290/067 ,  C08F290/08 ,  C08F290/14

摘要： A UV-curable acrylate-thiol-ene insulating coating composition for electrical conductors, a method of manufacturing a UV-curable acrylate-thiol-ene insulating coating composition for electrical conductors. The insulating coating being of about 2.5 nullm to about 500 nullm thickness, which cured coating has a dielectric dissipation factor (60Hz, 24null C.) of lower than about 0.05.

摘要翻译： 用于电导体的可紫外线固化的丙烯酸酯 - 硫醇烯绝缘涂料组合物，用于制造用于导电体的可UV固化的丙烯酸酯 - 硫醇烯绝缘涂料组合物的方法。 绝缘涂层的厚度约为2.5μm至约500μm，该固化涂层的介电损耗因子（60Hz，24℃）低于约0.05。

公开(公告)号：US3697312A

公开(公告)日：1972-10-10

申请号：US3697312D

申请日：1970-12-21

申请人： FORD MOTOR CO

发明人： JOHNSON OLIN B ,  LABANA SANTOKH S

IPC分类号： C08F2/44 ,  C08F8/00 ,  C08F265/06 ,  C08F285/00 ,  C08F299/02 ,  C08F299/04 ,  C08F299/06 ,  C08G18/67 ,  C08G63/06 ,  C08G63/47 ,  C08G63/52 ,  C08G63/676 ,  C08L67/06 ,  C09D4/06 ,  C09D163/10 ,  C09D167/00 ,  C08F15/00 ,  C08G41/04

CPC分类号： C09D163/10 ,  C08F8/00 ,  C08F265/06 ,  C08F285/00 ,  C08F299/024 ,  C08F299/026 ,  C08F299/04 ,  C08F299/0485 ,  C08F299/065 ,  C08G18/672 ,  C08G63/06 ,  C08G63/47 ,  C08G63/52 ,  C08G63/676 ,  C08L67/06 ,  C09D4/06 ,  C09D167/00 ,  Y10S525/902 ,  Y10S525/904 ,  Y10S525/913 ,  Y10T428/24405 ,  Y10T428/2998 ,  Y10T428/31511 ,  Y10T428/31525 ,  Y10T428/31529 ,  Y10T428/31551 ,  Y10T428/31591 ,  Y10T428/31601 ,  Y10T428/31605 ,  Y10T428/31699 ,  Y10T428/31786 ,  Y10T428/3179 ,  Y10T428/31794 ,  Y10T428/31826 ,  Y10T428/31895 ,  Y10T428/31906 ,  Y10T428/31909 ,  Y10T428/31924 ,  Y10T428/31989 ,  C08G18/62 ,  C08F290/14 ,  C08F290/08 ,  C08L2666/04

摘要： A RADIATION-CURABLE PAINT BINDER DISPERSION COMPRISES VINYL MONOMERS, AN ALPHA-BETA OLEFINICALLY UNSATURATED EPOXY RESIN HAVING MOLECULAR WEIGHT IN EXCESS OF ABOUT 370, AND AN ADDITION PRODUCT OF A HYDROXY-FUNCTIONAL GRADED RUBBER PARTICLE, A DIISOCYANATE AND A HYDROXYALKYL ACRYLATE. THE DISPERSION IS APPLIED TO SUBSTRATES AND CURED THEREON BY EXPOSURE TO IONIZING RADIATION, E.G., AN ELECTRON BEAM.

公开(公告)号：US3689309A

公开(公告)日：1972-09-05

申请号：US3689309D

申请日：1970-12-21

申请人： FORD MOTOR CO

发明人： JOHNSON OLIN B ,  LABANA SANTOKH S

IPC分类号： C08F2/44 ,  C08F8/00 ,  C08F265/06 ,  C08F285/00 ,  C08F299/02 ,  C08F299/04 ,  C08F299/06 ,  C08G18/67 ,  C08G63/06 ,  C08G63/47 ,  C08G63/52 ,  C08G63/676 ,  C08L67/06 ,  C09D4/06 ,  C09D163/10 ,  C09D167/00 ,  C08G45/04

CPC分类号： C09D163/10 ,  C08F8/00 ,  C08F265/06 ,  C08F285/00 ,  C08F299/024 ,  C08F299/026 ,  C08F299/04 ,  C08F299/0485 ,  C08F299/065 ,  C08G18/672 ,  C08G63/06 ,  C08G63/47 ,  C08G63/52 ,  C08G63/676 ,  C08L67/06 ,  C09D4/06 ,  C09D167/00 ,  Y10S525/902 ,  Y10S525/904 ,  Y10S525/913 ,  Y10T428/24405 ,  Y10T428/2998 ,  Y10T428/31511 ,  Y10T428/31525 ,  Y10T428/31529 ,  Y10T428/31551 ,  Y10T428/31591 ,  Y10T428/31601 ,  Y10T428/31605 ,  Y10T428/31699 ,  Y10T428/31786 ,  Y10T428/3179 ,  Y10T428/31794 ,  Y10T428/31826 ,  Y10T428/31895 ,  Y10T428/31906 ,  Y10T428/31909 ,  Y10T428/31924 ,  Y10T428/31989 ,  C08G18/62 ,  C08F290/14 ,  C08F290/08 ,  C08L2666/04

摘要： A RADIATION-CURABLE PAINT WHICH ON A PIGMENT AND PARTICULATE FILLER-FREE BASIS CONSISTS ESSENTIALLY OF VINYL MONOMERS AND A UNIQUE, ALPHA-BETA OLEFINICALLY UNSATURATED, RUBBER-COMPRISING RESIN FORMED BY A REACTING A MONOEPOXY COPOLYMER OF VINYL MONOMERS WITH A CARBOXY-FUNCTIONAL GRADED-RUBBER PARTICLE AND REACTING THE RESULTANT HYDROXYL GROUPS THEREON WITH ACRYLYL CHLORIDE OR METHACRYLYL CHLORIDE.

公开(公告)号：US3459690A

公开(公告)日：1969-08-05

申请号：US3459690D

申请日：1967-01-24

申请人： PPG INDUSTRIES INC

发明人： BAUGH ROBERT A ,  OSTROWSKI JOHN S ,  ZWACK ROBERT R

IPC分类号： C08F290/08 ,  C08G63/91 ,  C09D167/08 ,  C09D183/10 ,  C08F21/00 ,  C08G47/10

CPC分类号： C09D183/10 ,  C08F290/08 ,  C08G63/91 ,  C09D167/08

公开(公告)号：US09683070B2

公开(公告)日：2017-06-20

申请号：US15340213

申请日：2016-11-01

申请人： WASHINGTON STATE UNIVERSITY

发明人： Jinwen Zhang ,  Wenjia Song

IPC分类号： C08F2/00 ,  C08H1/00 ,  C08F290/08 ,  A61L15/24 ,  A61L15/60 ,  A61L15/62

CPC分类号： C08F290/08 ,  A61L15/24 ,  A61L15/32 ,  A61L15/40 ,  A61L15/60 ,  A61L15/62

摘要： A novel bio-based superabsorbent polymer material based on a proteinaceous natural polymer is introduced herein. There is further disclosed a method for the manufacture of such a bio-based crosslinked superabsorbent polymer material. The method includes, but not limited to, introducing polymerizable unsaturated groups onto the natural polymer or its derivative so as to yield a macromonomer. The macromonomer can be formed by covalently binding unsaturated carbon-carbon double bonds to a proteinaceous substrate through a reaction of a selected chemical compound and the amino group on the proteinaceous substrate. The macromonomer is then copolymerized with unsaturated co-monomer(s) to form a crosslinked superabsorbent material.