System for separation of a sample
    22.
    发明授权
    System for separation of a sample 有权
    样品分离系统

    公开(公告)号:US09314790B1

    公开(公告)日:2016-04-19

    申请号:US12796385

    申请日:2010-06-08

    摘要: A centrifuge layering insert configured for insertion into a centrifuge tube includes a tube having a first open end and a second open end. The centrifuge layering insert also includes a casing having an outer wall, an inner wall, a first open end, and a second substantially closed end. The casing forms an annular space around the tube between the tube first end and the tube second end. The tube has at least a portion of the length extending beyond the first open end of the casing in a direction opposite the second open end of the tube.

    摘要翻译: 构造成用于插入到离心管中的离心机分层插入件包括具有第一开口端和第二开口端的管。 离心机分层插入件还包括具有外壁,内壁,第一开口端和第二基本封闭端的壳体。 套管在管的第一端和管的第二端之间形成围绕管的环形空间。 管具有至少一部分长度在与管的第二开口端相反的方向上延伸超过壳体的第一开口端。

    Microchip, measurement system and method using the same, and test reagent to be used for microchip
    23.
    发明授权
    Microchip, measurement system and method using the same, and test reagent to be used for microchip 有权
    Microchip的测量系统和使用该仪器的方法以及用于微芯片的测试试剂

    公开(公告)号:US09274107B2

    公开(公告)日:2016-03-01

    申请号:US13474863

    申请日:2012-05-18

    申请人: Shun Momose

    发明人: Shun Momose

    摘要: A microchip to be used for measuring a plurality of types of objects to be measured. The microchip includes at least a reagent retaining portion and a detecting portion. The test reagent retaining portion includes a plurality of types of test reagents corresponding respectively to the plurality of types of objects to be measured. A plurality of time courses for a change in detected value at the detecting portion caused by a reaction between the test reagents and the objects to be measured corresponding respectively thereto are all different from each other.

    摘要翻译: 一种微芯片,用于测量待测量的多种类型的物体。 微芯片至少包括试剂保持部和检测部。 测试试剂保持部分包括分别对应于待测量的多种类型的物体的多种试验试剂。 由测试试剂和与其分别对应的测量对象之间的反应引起的检测部分处的检测值的变化的多个时间过程彼此不同。

    Method of optical analysis using reference cell and base plate correction and apparatus thereof
    24.
    发明授权
    Method of optical analysis using reference cell and base plate correction and apparatus thereof 有权
    使用参考电池和基板校正的光学分析方法及其装置

    公开(公告)号:US09176049B2

    公开(公告)日:2015-11-03

    申请号:US12734067

    申请日:2008-10-29

    摘要: A method for analyzing a sample includes the step of irradiating a reaction portion of a sample BL and a reagent 40 in a reaction cell 34A of an analysis unit with light to obtain data D0 indicating optical characteristics of this portion. The method further includes the steps of irradiating a reference cell 34B which is not provided with a reagent 40 with light in a state in which the sample BL is supplied to the cell to obtain reference data D1 indicating optical characteristics of this portion, irradiating a base portion 34C of the analysis unit with light to obtain reference data D2 indicating optical characteristics of this portion, and obtaining data D3 indicating optical characteristics of the sample BL before reaction with the reagent 40 based on the reference data D1 and D2.

    摘要翻译: 用于分析样品的方法包括用光照射分析单元的反应单元34A中的样品BL和试剂40的反应部分以获得指示该部分的光学特性的数据D0的步骤。 该方法还包括以下步骤:在样本BL被提供给细胞的状态下照射不具有试剂40的参考单元34B,以获得指示该部分的光学特性的参考数据D1,照射基底 分析单元的部分34C,以获得指示该部分的光学特性的参考数据D2,并且基于参考数据D1和D2,获得指示与反应物40反应之前样品BL的光学特性的数据D3。

    Microfluidic apparatus
    27.
    发明授权
    Microfluidic apparatus 有权
    微流量装置

    公开(公告)号:US09108198B2

    公开(公告)日:2015-08-18

    申请号:US14052464

    申请日:2013-10-11

    IPC分类号: B01L3/00 G01N21/07

    摘要: Provided is a microfluidic apparatus that is mounted on a rotation driver and induces a flow of a fluid due to a centrifugal force, the microfluidic apparatus including: a separation unit that separates a target cell from a sample; a recovery chamber that is connected to the separation unit through a recovery channel and accommodates the target cell obtained by the separation; and an inclined portion that is disposed in the recovery chamber and tilted toward a bottom of the recovery chamber along a direction of the centrifugal force.

    摘要翻译: 提供了一种微流体装置,其安装在旋转驱动器上并且由于离心力而引起流体流动,所述微流体装置包括:分离单元,其将目标细胞与样品分离; 回收室,其通过回收通道连接到分离单元,并容纳通过分离获得的靶单元; 以及倾斜部,其设置在所述回收室中并沿着所述离心力的方向朝向所述回收室的底部倾斜。

    Disc-like assay chip
    28.
    发明授权
    Disc-like assay chip 有权
    盘状分析芯片

    公开(公告)号:US09005547B2

    公开(公告)日:2015-04-14

    申请号:US13428683

    申请日:2012-03-23

    摘要: The present invention provides a disc-like assay chip, and more specifically, the present invention provides an assay chip which can effectively clean a cleaned object existing in a fluid loop, and can be appropriately applied to a detection method of a reaction system using a step of necessarily cleaning the cleaned object, such as an immunofluorescent antibody method, and applied to a detection method using an enzymatic reaction (especially, an ELISA method). The present invention further provides a disc-like assay chip which is mounted on a centrifugal device such as a rotational disc and can perform detection or quantitation on a target substance through optical measurement after a specimen and a reagent react by use of a centrifugal force generated by rotation of the centrifugal device.

    摘要翻译: 本发明提供一种盘状测定芯片,更具体地说,本发明提供一种能够有效地清洁存在于流体回路中的被清洁物体的测定芯片,并且可以适当地应用于使用 必须清洁被清洁物体的步骤,例如免疫荧光抗体法,并应用于使用酶反应的检测方法(特别是ELISA法)。 本发明还提供了一种盘状测定芯片,其安装在诸如旋转盘的离心装置上,并且可以通过使用产生的离心力在样品和试剂反应之后通过光学测量对目标物质进行检测或定量 通过离心装置的旋转。

    Microfluidic flow cell
    29.
    发明授权
    Microfluidic flow cell 有权
    微流控流动池

    公开(公告)号:US08277759B2

    公开(公告)日:2012-10-02

    申请号:US12920577

    申请日:2009-03-03

    IPC分类号: G01N21/07 G01N21/01 C12Q1/68

    摘要: A microfluidic flow cell having a body with a fluid transport channel disposed therein, the fluid transport channel having a proximal end and a distal end defining a fluid flow path, a fluid inlet port disposed at the proximal end of the fluid transport channel at a central portion of the body and an outlet port disposed at the distal end of the fluid transport channel at an outer portion of the body, and a plurality sample wells disposed in the fluid transport channel substantially perpendicular to the fluid flow path in the fluid transport channel. The microfluidic flow cell may have hundreds or thousands of individual, sub-microliter sample wells. The microfluidic flow cell can be filled by applying a flowable liquid to the inlet port and spinning the flow cell to cause fluid to flow into fluid transport channel. The microfluidic flow cells described herein can be used in a variety of applications where small sample size and/or a large number of replicates are desirable.

    摘要翻译: 一种微流体流动池,其具有设置在其中的流体输送通道的主体,所述流体输送通道具有限定流体流动路径的近端和远端;流体入口,其设置在所述流体输送通道的近端处的中心 主体的一部分和设置在主体的外部部分处的流体输送通道的远端处的出口端口以及设置在流体输送通道中的基本上垂直于流体输送通道中的流体流动路径的多个样本阱。 微流体流动池可以具有数百或数千个单独的亚微升样品孔。 可以通过将可流动的液体施加到入口端口并旋转流动池以使流体流入流体输送通道来填充微流体流动池。 本文所述的微流体流动池可以用于需要小样品量和/或大量重复的各种应用中。

    Optical Cup
    30.
    发明申请
    Optical Cup 有权
    光学杯

    公开(公告)号:US20120105837A1

    公开(公告)日:2012-05-03

    申请号:US13286503

    申请日:2011-11-01

    申请人: Gal INGBER

    发明人: Gal INGBER

    IPC分类号: G01N21/07 G01N21/03

    摘要: The present invention relates to a system for conducting the identification and quantification of micro-organisms, e.g., bacteria in biological samples. More particularly, the invention relates to a system comprising a disposable cartridge and an optical cup or cuvette having a tapered surface; wherein the walls are angled to allow for better coating and better striations of the light, an optics system including an optical reader and a thermal controller; an optical analyzer; a cooling system; and an improved spectrometer. The system may utilize the disposable cartridge in the sample processor and the optical cup or cuvette in the optical analyzer.

    摘要翻译: 本发明涉及用于进行微生物(例如生物样品中的细菌)的鉴定和定量的系统。 更具体地,本发明涉及一种包括一次性盒和具有锥形表面的光学杯或比色杯的系统; 其中所述壁成角度以允许所述光的更好的涂覆和更好的条纹,包括光学读取器和热控制器的光学系统; 光学分析仪; 冷却系统; 和改进的光谱仪。 该系统可以利用样品处理器中的一次性盒,以及光学分析仪中的光学杯或反应杯。