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31.发明授权公开(公告)号：US12076463B2
公开(公告)日：2024-09-03
申请号：US17849893
申请日：2022-06-27
Applicant: DSM IP Assets B.V. , ACADEMISCH ZIEKENHUIS MAASTRICHT
Inventor： Jens Christoph Thies , Ruud Jozef Regina Wilhelmus Peters , Pieter J. Emans , Jacob Koenen
CPC classification number: A61L27/46 , A61L27/446 , A61L27/54 , A61L27/56 , A61L2420/02 , A61L2420/04 , A61L2430/02 , C08L75/04
Abstract: The disclosure relates to methods of making an osteoconductive polymer article for use as an orthopedic implant comprises steps of forming an article from a biocompatible, non-biodegradable polymer, the article comprising a non-flat surface with roughness Ra of at least 5 μm; providing a dispersion of bioactive ceramic particles of particle size at most 10 μm in a first solvent comprising a solvent for the polymer; coating at least the non-flat surface with the dispersion in at least one step; and rinsing the coated article with a second solvent being a non-solvent for the polymer to substantially remove the first solvent.
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32.发明公开公开(公告)号：US20240240137A1
公开(公告)日：2024-07-18
申请号：US18419326
申请日：2024-01-22
Applicant: DSM IP Assets B.V.
Inventor： Mariya Alexeevna TARAZANOVA , Thom HUPPERTZ , Herwig BACHMANN , Jan KOK , Marke BEERTHUYZEN
IPC: C12N1/20 , A23C9/123 , A23L33/135 , C07K14/195 , C07K14/315 , C12R1/46
CPC classification number: C12N1/20 , A23C9/1236 , A23L33/135 , C07K14/195 , C07K14/315 , C12N1/205 , A23V2400/131 , A23V2400/157 , A23V2400/249 , C12R2001/46
Abstract: The present invention relates to the field of microbiology, specifically the field of production of a dairy food product using fermentation and the field of gene transfer by conjugation.
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公开(公告)号：US20240239839A1
公开(公告)日：2024-07-18
申请号：US18559242
申请日：2022-05-03
Applicant: DSM IP Assets B.V.
Inventor： Marc HEIDL , Thomas SCHAERER , Alexander SCHLIFKE-POSCHALKO
Abstract: The present invention relates to purification of a tripeptide of formula (I). By using said method, the tripeptide of formula (I) is obtained in a very pure form and due to this effect the purified tripeptide can be used in a variety of cosmetic and pharmaceutic compositions which are not accessible for the respective unpurified tripeptide.
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公开(公告)号：US20240225062A9
公开(公告)日：2024-07-11
申请号：US18546604
申请日：2022-02-18
Applicant: DSM IP Assets B.V.
Inventor： Frits BROUWER , Petrus Paulus Gerardus Anna VERHOEVEN
CPC classification number: A23L27/215 , A23J3/16 , A23J3/227 , A23L27/2052 , A23L27/2056 , A23P20/11
Abstract: The present invention relates to a meat substitute provided with a flavour agent coating, optionally wherein the weight of the flavour agent coating is between 0.1% and 5% of the weight of the coated meat substitute.
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35.发明公开公开(公告)号：US20240217941A1
公开(公告)日：2024-07-04
申请号：US18557241
申请日：2022-04-26
Applicant: DSM IP Assets B.V.
Inventor： Werner BONRATH , Rolf KUENZI , Meltem TIRPANCI , Thomas NETSCHER
IPC: C07D311/72 , C07D311/92
CPC classification number: C07D311/72 , C07D311/92
Abstract: The present invention relates to the formation of compound of the formula (I) by a ring closure reaction of the compound of the formula (II) in the presence of a catalytic amounts of a base. It has been found that this reaction is very efficient and offers for example an efficient pathway for the synthesis of 3,4-dehydro-α-tocotrienol respectively α-tocotrienol and α-tocopherol.
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Patent Agency Ranking
公开(公告)号：US20240207203A1
公开(公告)日：2024-06-27
申请号：US18555095
申请日：2022-04-12
Applicant: DSM IP Assets B.V.
Inventor： Maik KINDERMANN , Ulla LETINOIS , Luis Fernando MONTEIRO TAMASSIA , René Tobias STEMMLER , Nicola WALKER
IPC: A61K31/11 , A61K31/045 , A61K47/02 , A61K47/10 , A61P1/14
CPC classification number: A61K31/11 , A61K31/045 , A61K47/02 , A61K47/10 , A61P1/14
Abstract: The present invention relates to the field of reduction of methane emission in ruminants. Particularly, it relates to the administration of gossypol and propanediol mononitrate to a ruminant for reducing the production of methane emanating from the digestive activities of said ruminant.
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公开(公告)号：US20240197609A1
公开(公告)日：2024-06-20
申请号：US18555070
申请日：2022-04-13
Applicant: DSM IP ASSETS B.V.
Inventor： Linda HAENDEL , Lise KOHLER , Fabiola PORTA , Pascal Christian SIEBER , Christos TSEKOU
CPC classification number: A61K8/671 , A61K8/498 , A61K8/604 , A61Q19/00 , A61K2800/10
Abstract: The present invention relates to a new formulation, which comprises a high amount of retinol in a specific solvent and in the presence of mixed tocopherol.
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公开(公告)号：US20240188590A1
公开(公告)日：2024-06-13
申请号：US18063528
申请日：2022-12-08
Applicant: Novozymes A/S , DSM IP Assets B.V.
Inventor： Flemming Borup , Ivan De Jesus Gaytan Perez
IPC: A23K20/189 , A23K40/10 , A23K40/20 , A23K40/30
CPC classification number: A23K20/189 , A23K40/10 , A23K40/20 , A23K40/30
Abstract: An animal feed comprising an animal feed additive, said additive comprising co-granules, each co-granule comprising at least two classes of enzymes, said co-granules comprising a core unit and a protective coating such that the dose of each of the enzymes in the feed is set in each granule rather than by the level of homogeneity of single-enzyme granules or by the efficiency of the mixing.
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公开(公告)号：US20240180183A1
公开(公告)日：2024-06-06
申请号：US17905201
申请日：2021-03-09
Applicant: DSM IP ASSETS B.V.
Inventor： Petrus Jacobus Theodorus DEKKER
CPC classification number: A23C9/1206 , A23C9/1216 , A23C9/16 , C12N9/1051 , C12N9/2471 , C12Y204/01 , C12Y302/01023
Abstract: The invention relates to the field of dry or powder dairy compositions. The present invention describes a method for producing a lactose reduced dairy powder comprising
(i) treating a lactose comprising milk-based substrate with a first enzyme having transgalactosylase activity and a second enzyme having lactase activity to obtain a lactose reduced and galacto-oligosaccharides (GOS) comprising milk-based product
(ii) preparing lactose reduced dairy powder from said lactose reduced and GOS comprising milk-based product.-
公开(公告)号：US11999837B2
公开(公告)日：2024-06-04
申请号：US17045061
申请日：2019-04-08
Applicant: DSM IP Assets B.V.
CPC classification number: C08J9/42 , C08J5/18 , C08L23/06 , C08L75/08 , C08J2207/10 , C08J2323/06 , C08J2475/08 , C08L2203/02 , C08L2207/04 , C08L2207/068
Abstract: Disclosed herein is a porous hybrid elastomer/polyolefin film, which is a porous polyolefin film wherein at one or more isolated areas of the film pores are at least partly filled with an elastomer. This hybrid film shows improved resistance to tearing, whereas other properties like porosity, polarity, thickness, flexibility, and non-stickiness of the film are substantially retained. Other advantages include improved suture retention. The invention also provides a method to increase tear resistance of a porous polyolefin film comprising steps of providing a porous polyolefin film; identifying one or more locations on the film, at which locations tearing is likely to occur during intended use of the film; applying at the identified locations of the film an amount of a solution of an elastomer in solvent; and substantially removing the solvent; to result in a hybrid elastomer/polyolefin film having one or more isolated areas where pores in the film are at least partly filled with the elastomer. Further aspects concern uses of these hybrid films as a component of a medical implant or device, especially for use in contact with body tissue or fluids, such as in vascular applications like a vascular graft, a stent cover or a catheter balloon; and medical devices or implants comprising said porous hybrid films.
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