Glucometer comprising an implantable light source
    31.
    发明申请
    Glucometer comprising an implantable light source 审中-公开
    含有可植入光源的葡萄糖计

    公开(公告)号:US20070004974A1

    公开(公告)日:2007-01-04

    申请号:US10596939

    申请日:2004-12-23

    IPC分类号: A61B5/00 A61B8/00

    摘要: Apparatus for assaying an analyte in a body comprising: at least one light source implanted in the body controllable to illuminate a tissue region in the body with light at at least one wavelength that is absorbed by the analyte and as a result generates photoacoustic waves in the tissue region; at least one acoustic sensing transducer coupled to the body that receives acoustic energy from the photoacoustic waves and generates signals responsive thereto; and a processor that receives the signals and processes them to determine a concentration of the analyte in the illuminated tissue region.

    摘要翻译: 用于测定体内分析物的装置,包括:植入人体内的至少一个光源可被控制以用被分析物吸收的至少一个波长的光照射身体中的组织区域,并因此产生光声波 组织区域 耦合到所述主体的至少一个声学传感传感器,其从所述光声波接收声能并响应于此产生信号; 以及接收信号并处理它们以确定被照射的组织区域中的分析物的浓度的处理器。

    Photoacoustic Assay Method and Apparatus
    37.
    发明申请
    Photoacoustic Assay Method and Apparatus 审中-公开
    光声测定方法和装置

    公开(公告)号:US20080194929A1

    公开(公告)日:2008-08-14

    申请号:US10551543

    申请日:2004-03-29

    IPC分类号: A61B5/1455 A61B8/00

    摘要: Apparatus (20, 100) for assaying a target analyte in a localized tissue region (22) that may include the target and other analytes comprising: a light source (34, 104) that illuminates the region with light at each of a plurality of wavelengths at which light is absorbed and/or scattered by tissue in the region wherein light at a least one of the wavelengths is absorbed or scattered by the target analyte; a signal generator (40) that generates signals responsive to intensity of the light from the light source (34, 104) at different locations in the localized region (22); and a controller (32, 102) that: receives the generated signals; processes the signals to determine an extinction coefficient for light in the localized region at each wavelength; and determines the concentration of the target analyte responsive to a solution of a set of simultaneous equations having as unknown variables concentrations of a plurality of analytes in the region (22), one of which is the target analyte, wherein each equation in the set expresses a relationship between the extinction coefficient, the absorption coefficient and/or the reduced scattering coefficient for light at a different one of the plurality of wavelengths and at least one of the equations expresses a relationship between the extinction coefficient and the reduced scattering coefficient.

    摘要翻译: 用于测定局部组织区域(22)中可能包括目标物和其它分析物的靶分析物的装置(20,100),包括:光源(34,104),其以多个波长中的每一个的光照射该区域 在该区域中的组织被光吸收和/或散射,其中至少一个波长的光被靶分析物吸收或散射; 信号发生器(40),其在所述局部区域(22)中的不同位置处产生响应于来自所述光源(34,104)的光的强度的信号; 以及控制器(32,102),其接收所生成的信号; 处理信号以确定每个波长处的局部区域中的光的消光系数; 并且确定目标分析物的浓度,其响应于在区域(22)中具有多个分析物浓度的未知变量的一组联立方程(其中一个是目标分析物)的溶液的溶液,其中集合中的每个方程表示 在多个波长中的不同一个波长处的光的消光系数,吸收系数和/或减小的散射系数之间的关系以及至少一个等式表示消光系数和降低的散射系数之间的关系。

    Wearable glucometer
    38.
    发明申请
    Wearable glucometer 审中-公开
    可戴式血糖仪

    公开(公告)号:US20060258939A1

    公开(公告)日:2006-11-16

    申请号:US10559974

    申请日:2004-06-08

    IPC分类号: A61B8/00

    摘要: Apparatus for assaying an analyte of blood in a patient's blood vessel comprising: a mounting module adapted so that it can be adhered to the skin of the patient overlying a tissue region comprising the blood vessel; a sensor unit mounted to the module that generates signals responsive to characteristics of the tissue region; and a controller that receives the signals and uses received signals to assay the analyte and to determine a degree to which the sensor unit is aligned with the blood vessel.

    摘要翻译: 用于测定患者血管中的血液分析物的装置,包括:安装模块,其适于使其能够粘附到覆盖在包括血管的组织区域的患者皮肤上; 安装到模块的传感器单元,其响应于组织区域的特性产生信号; 以及控制器,其接收信号并使用接收的信号来测定分析物并确定传感器单元与血管对准的程度。

    Ultrasonic position indicator
    39.
    发明授权
    Ultrasonic position indicator 有权
    超声波位置指示器

    公开(公告)号:US07068867B2

    公开(公告)日:2006-06-27

    申请号:US10335703

    申请日:2003-01-02

    IPC分类号: G02B6/00

    摘要: A system for monitoring a position of an instrument in a subject includes a light transmission medium configured to transmit light pulses to a desired region to produce an acoustic signal, at least one ultrasound sensor configured to receive the acoustic signal and to produce a transduced signal from the acoustic signal, and a processing unit connected to the at least one ultrasound sensor and configured to locate a source of the acoustic signal using the transduced signal.

    摘要翻译: 用于监测被检者中的器械的位置的系统包括:光传输介质,被配置为将光脉冲传输到期望的区域以产生声信号;至少一个超声传感器,被配置为接收声信号并产生从 所述声信号以及连接到所述至少一个超声波传感器并被配置为使用所述转导信号来定位所述声信号的源的处理单元。

    Photoacoustic assay method and apparatus
    40.
    发明申请
    Photoacoustic assay method and apparatus 审中-公开
    光声测定方法和装置

    公开(公告)号:US20060264717A1

    公开(公告)日:2006-11-23

    申请号:US10542600

    申请日:2004-01-13

    IPC分类号: A61B5/00

    摘要: A method of assaying an analyte in a body part comprising: illuminating the body part with at least one pulse of light at each of first and second wavelengths that stimulates photoacoustic waves in a first, target, region and a second, reference, region of the body part, wherein the reference region interfaces with the target region and has at least one known optoacoustic property and wherein light at the first wavelength is absorbed by the analyte; sensing pressure in the photoacoustic waves from the target and reference regions stimulated by the light at the first and second wavelengths; and using the sensed pressures and the at least one known optoacoustic property to assay the analyte in the target region.

    摘要翻译: 一种测定身体部位中的分析物的方法,包括:用在第一和第二波长中的每一个处的至少一个脉冲光照射身体部分,以刺激第一,目标,区域和第二参考区域中的光声波 其中所述参考区域与所述目标区域接合并且具有至少一个已知的光声特性,并且其中所述第一波长处的光被所述分析物吸收; 感测来自由第一和第二波长的光刺激的目标和参考区域的光声波中的压力; 以及使用感测到的压力和至少一种已知的光声特性来测定目标区域中的分析物。