-
公开(公告)号:US20070004974A1
公开(公告)日:2007-01-04
申请号:US10596939
申请日:2004-12-23
申请人: Ron Nagar , Gabriel Bitton , Benny Pesach
发明人: Ron Nagar , Gabriel Bitton , Benny Pesach
CPC分类号: G01N21/1702 , A61B5/0031 , A61B5/0095 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/1459 , A61B2560/0219
摘要: Apparatus for assaying an analyte in a body comprising: at least one light source implanted in the body controllable to illuminate a tissue region in the body with light at at least one wavelength that is absorbed by the analyte and as a result generates photoacoustic waves in the tissue region; at least one acoustic sensing transducer coupled to the body that receives acoustic energy from the photoacoustic waves and generates signals responsive thereto; and a processor that receives the signals and processes them to determine a concentration of the analyte in the illuminated tissue region.
摘要翻译: 用于测定体内分析物的装置,包括:植入人体内的至少一个光源可被控制以用被分析物吸收的至少一个波长的光照射身体中的组织区域,并因此产生光声波 组织区域 耦合到所述主体的至少一个声学传感传感器,其从所述光声波接收声能并响应于此产生信号; 以及接收信号并处理它们以确定被照射的组织区域中的分析物的浓度的处理器。
-
公开(公告)号:US20060079809A1
公开(公告)日:2006-04-13
申请号:US11048108
申请日:2005-02-01
申请人: Daniel Goldberger , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidon Pesach , Gabriel Bitton , Ron Nagar
发明人: Daniel Goldberger , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidon Pesach , Gabriel Bitton , Ron Nagar
IPC分类号: A61B5/00
CPC分类号: A61B5/14532 , A61B5/0215 , A61B5/14535 , A61B5/14546 , A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150305 , A61B5/150358 , A61B5/150366 , A61B5/150755 , A61B5/150992 , A61B5/155 , A61B5/157 , A61M5/14232 , A61M5/1723 , A61M2005/1726 , A61M2205/12 , A61M2230/201 , G06F19/00 , Y10T436/11 , Y10T436/117497
摘要: The present invention is directed towards apparatuses and methods for the automated measurement of blood analytes and blood parameters for bedside monitoring of patient blood chemistry. Particularly, the current invention discloses a programmable system that can automatically draw blood samples at a suitable programmable time frequency (or at predetermined timing), can automatically analyze the drawn blood samples and immediately measure and display blood parameters such as glucose levels, hematocrit levels, hemoglobin blood oxygen saturation, blood gases, lactate or any other blood parameter.
-
公开(公告)号:US20110144463A1
公开(公告)日:2011-06-16
申请号:US12918828
申请日:2009-02-26
申请人: Benny Pesach , Gabriel Bitton , Ron Nagar
发明人: Benny Pesach , Gabriel Bitton , Ron Nagar
IPC分类号: A61B5/1468
CPC分类号: A61B5/1519 , A61B5/0022 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/1477 , A61B5/150022 , A61B5/150076 , A61B5/150083 , A61B5/150091 , A61B5/150267 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150748 , A61B5/150755 , A61B5/150854 , A61B5/150862 , A61B5/15087 , A61B5/15109 , A61B5/15117 , A61B5/15142 , A61B5/157 , A61B5/4839 , A61B5/6833 , A61B5/7285 , A61B5/742 , A61B5/746 , A61B2560/0285 , A61B2560/045
摘要: The present invention relates to a device, system and a method for measuring an analyte and in particular, to such a device, system and method in which analyte from a bodily fluid is measured and/or monitored.
摘要翻译: 本发明涉及用于测量分析物的装置,系统和方法,特别涉及测量和/或监测来自体液的分析物的这种装置,系统和方法。
-
公开(公告)号:US20100174225A1
公开(公告)日:2010-07-08
申请号:US12450251
申请日:2008-03-19
申请人: Benny Pesach , Gabriel Bitton , Ram Weiss , Ron Nagar
发明人: Benny Pesach , Gabriel Bitton , Ram Weiss , Ron Nagar
CPC分类号: A61M5/31 , A61B18/08 , A61B18/14 , A61B18/1477 , A61B18/18 , A61B18/20 , A61B2018/1425 , A61F7/007 , A61M5/14244 , A61M5/158 , A61M5/16831 , A61M5/1723 , A61M5/19 , A61M5/20 , A61M5/2448 , A61M5/422 , A61M2005/1581 , A61M2005/1726 , A61M2205/05 , A61M2205/051 , A61M2205/052 , A61M2205/054 , A61M2205/057 , A61M2205/058 , A61N1/30 , A61N7/00 , A61N2005/0645
摘要: The present disclosure presents systems, devices and methods for injection of drugs, substances and/or chemicals to a patient and for improving their effectiveness once they are injected are disclosed. Additional treatment can be applied to a tissue region on the patient into which a drug (e.g., insulin) is injected, to expose the tissue region to various forms of energy or a substance to improve the drug's pharmacokinetic and/or pharmacodynamic profile.
摘要翻译: 本公开内容公开了向患者注射药物,物质和/或化学物质并且一旦注射后提高其效力的系统,装置和方法。 可以对注射药物(例如胰岛素)的患者的组织区域施加额外的治疗,以将组织区域暴露于各种形式的能量或物质以改善药物的药代动力学和/或药效学特征。
-
公开(公告)号:US20100020309A1
公开(公告)日:2010-01-28
申请号:US12574642
申请日:2009-10-06
申请人: Daniel GOLDBERGER , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidon Pesach , Gabriel Bitton , Ron Nagar
发明人: Daniel GOLDBERGER , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidon Pesach , Gabriel Bitton , Ron Nagar
CPC分类号: A61B5/157 , A61B5/145 , A61B5/14532 , A61B5/14535 , A61B5/14539 , A61B5/14546 , A61B5/14557 , A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150358 , A61B5/150366 , A61B5/150755 , A61B5/150862 , A61B5/15087 , A61B5/150946 , A61B5/150992 , A61B5/153 , A61B5/155 , A61M5/14232 , A61M5/1723 , A61M2005/1726 , A61M2230/201
摘要: The present invention is directed towards apparatuses and methods for the automated measurement of blood analytes and blood parameters for bedside monitoring of patient blood chemistry. Particularly, the current invention discloses a programmable system that can automatically draw blood samples at a suitable programmable time frequency (or at predetermined timing), can automatically analyze the drawn blood samples and immediately measure and display blood parameters such as glucose levels, hematocrit levels, hemoglobin blood oxygen saturation, blood gases, lactate or any other blood parameter.
摘要翻译: 本发明涉及用于患者血液化学物质床边监测的血液分析物和血液参数的自动测量的装置和方法。 特别地,本发明公开了一种可以以合适的可编程时间频率(或在预定时间)自动抽取血液样本的可编程系统,可以自动分析所抽取的血液样本并立即测量和显示血液参数,例如葡萄糖水平,血细胞比容水平, 血红蛋白血氧饱和度,血气,乳酸或任何其他血液参数。
-
公开(公告)号:US20080281297A1
公开(公告)日:2008-11-13
申请号:US11821230
申请日:2007-06-21
申请人: Benny Pesach , Ron Nagar , Gabriel Bitton , Ram Weiss
发明人: Benny Pesach , Ron Nagar , Gabriel Bitton , Ram Weiss
CPC分类号: A61M5/14244 , A61B18/08 , A61B18/14 , A61B18/1477 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2018/1425 , A61F7/007 , A61M5/1413 , A61M5/158 , A61M5/16831 , A61M5/1723 , A61M5/20 , A61M5/422 , A61M2005/1581 , A61M2005/1726 , A61M2039/1022 , A61M2205/05 , A61M2205/051 , A61M2205/052 , A61M2205/058 , A61M2205/8206 , A61N1/30 , A61N7/00 , A61N2005/0645
摘要: A method and a device for a delivery of a chemical substance to the body of the patient are provided. The device includes an infusion catheter configured to be inserted into a tissue, a catheter securing element configured to be adhered to the skin of the patient and further configured to secure the infusion catheter to the skin, a drug delivery pump configured to infuse a drug into the infusion catheter for delivery to a drug infused region on the body of the patient, and a treatment element configured to apply a treatment to the drug infused region to improve pharmacodynamics of the drug during a period of delivery of the drug to the patient.
摘要翻译: 提供了一种将化学物质输送到患者体内的方法和装置。 该装置包括构造成插入到组织中的输注导管,导管固定元件,其构造成粘附到患者的皮肤上,并进一步构造成将输注导管固定到皮肤上;药物输送泵,被配置为将药物注入 用于输送到患者身体上的药物输注区域的输注导管,以及配置成对药物输注区域施加治疗以改善药物递送到患者期间药物的药效学的治疗元件。
-
公开(公告)号:US20080194929A1
公开(公告)日:2008-08-14
申请号:US10551543
申请日:2004-03-29
申请人: Benny Pesach , Gabriel Bitton , Michal Balberg
发明人: Benny Pesach , Gabriel Bitton , Michal Balberg
IPC分类号: A61B5/1455 , A61B8/00
CPC分类号: A61B5/0066 , A61B5/0059 , A61B5/0095 , A61B5/14532 , A61B5/1455 , G01N21/1702 , G01N2021/1706
摘要: Apparatus (20, 100) for assaying a target analyte in a localized tissue region (22) that may include the target and other analytes comprising: a light source (34, 104) that illuminates the region with light at each of a plurality of wavelengths at which light is absorbed and/or scattered by tissue in the region wherein light at a least one of the wavelengths is absorbed or scattered by the target analyte; a signal generator (40) that generates signals responsive to intensity of the light from the light source (34, 104) at different locations in the localized region (22); and a controller (32, 102) that: receives the generated signals; processes the signals to determine an extinction coefficient for light in the localized region at each wavelength; and determines the concentration of the target analyte responsive to a solution of a set of simultaneous equations having as unknown variables concentrations of a plurality of analytes in the region (22), one of which is the target analyte, wherein each equation in the set expresses a relationship between the extinction coefficient, the absorption coefficient and/or the reduced scattering coefficient for light at a different one of the plurality of wavelengths and at least one of the equations expresses a relationship between the extinction coefficient and the reduced scattering coefficient.
摘要翻译: 用于测定局部组织区域(22)中可能包括目标物和其它分析物的靶分析物的装置(20,100),包括:光源(34,104),其以多个波长中的每一个的光照射该区域 在该区域中的组织被光吸收和/或散射,其中至少一个波长的光被靶分析物吸收或散射; 信号发生器(40),其在所述局部区域(22)中的不同位置处产生响应于来自所述光源(34,104)的光的强度的信号; 以及控制器(32,102),其接收所生成的信号; 处理信号以确定每个波长处的局部区域中的光的消光系数; 并且确定目标分析物的浓度,其响应于在区域(22)中具有多个分析物浓度的未知变量的一组联立方程(其中一个是目标分析物)的溶液的溶液,其中集合中的每个方程表示 在多个波长中的不同一个波长处的光的消光系数,吸收系数和/或减小的散射系数之间的关系以及至少一个等式表示消光系数和降低的散射系数之间的关系。
-
公开(公告)号:US20060258939A1
公开(公告)日:2006-11-16
申请号:US10559974
申请日:2004-06-08
申请人: Benny Pesach , Ron Nagar , Shai Ashkenazi , Gidon Pesach , Avner Adoram
发明人: Benny Pesach , Ron Nagar , Shai Ashkenazi , Gidon Pesach , Avner Adoram
IPC分类号: A61B8/00
CPC分类号: A61B5/489 , A61B5/0095 , A61B5/14532 , A61B5/1455 , A61B5/6833 , A61B8/0833 , A61B2560/0412
摘要: Apparatus for assaying an analyte of blood in a patient's blood vessel comprising: a mounting module adapted so that it can be adhered to the skin of the patient overlying a tissue region comprising the blood vessel; a sensor unit mounted to the module that generates signals responsive to characteristics of the tissue region; and a controller that receives the signals and uses received signals to assay the analyte and to determine a degree to which the sensor unit is aligned with the blood vessel.
摘要翻译: 用于测定患者血管中的血液分析物的装置,包括:安装模块,其适于使其能够粘附到覆盖在包括血管的组织区域的患者皮肤上; 安装到模块的传感器单元,其响应于组织区域的特性产生信号; 以及控制器,其接收信号并使用接收的信号来测定分析物并确定传感器单元与血管对准的程度。
-
公开(公告)号:US07068867B2
公开(公告)日:2006-06-27
申请号:US10335703
申请日:2003-01-02
申请人: Avner Adoram , Benny Pesach , Ron Nagar , Shai Ashkenazi , Michal Balberg
发明人: Avner Adoram , Benny Pesach , Ron Nagar , Shai Ashkenazi , Michal Balberg
IPC分类号: G02B6/00
CPC分类号: A61B8/0841 , A61B5/0095 , A61B5/061 , A61B5/6852 , A61B8/0833 , A61B17/3403 , A61B2090/3788
摘要: A system for monitoring a position of an instrument in a subject includes a light transmission medium configured to transmit light pulses to a desired region to produce an acoustic signal, at least one ultrasound sensor configured to receive the acoustic signal and to produce a transduced signal from the acoustic signal, and a processing unit connected to the at least one ultrasound sensor and configured to locate a source of the acoustic signal using the transduced signal.
摘要翻译: 用于监测被检者中的器械的位置的系统包括:光传输介质,被配置为将光脉冲传输到期望的区域以产生声信号;至少一个超声传感器,被配置为接收声信号并产生从 所述声信号以及连接到所述至少一个超声波传感器并被配置为使用所述转导信号来定位所述声信号的源的处理单元。
-
公开(公告)号:US20060264717A1
公开(公告)日:2006-11-23
申请号:US10542600
申请日:2004-01-13
申请人: Benny Pesach , Gabriel Bitton , Michal Balberg
发明人: Benny Pesach , Gabriel Bitton , Michal Balberg
IPC分类号: A61B5/00
CPC分类号: A61B5/1455 , A61B5/0095 , A61B5/14532 , G01N21/1702 , G01N29/2418 , G01N29/30 , G01N29/348 , G01N29/4427
摘要: A method of assaying an analyte in a body part comprising: illuminating the body part with at least one pulse of light at each of first and second wavelengths that stimulates photoacoustic waves in a first, target, region and a second, reference, region of the body part, wherein the reference region interfaces with the target region and has at least one known optoacoustic property and wherein light at the first wavelength is absorbed by the analyte; sensing pressure in the photoacoustic waves from the target and reference regions stimulated by the light at the first and second wavelengths; and using the sensed pressures and the at least one known optoacoustic property to assay the analyte in the target region.
摘要翻译: 一种测定身体部位中的分析物的方法,包括:用在第一和第二波长中的每一个处的至少一个脉冲光照射身体部分,以刺激第一,目标,区域和第二参考区域中的光声波 其中所述参考区域与所述目标区域接合并且具有至少一个已知的光声特性,并且其中所述第一波长处的光被所述分析物吸收; 感测来自由第一和第二波长的光刺激的目标和参考区域的光声波中的压力; 以及使用感测到的压力和至少一种已知的光声特性来测定目标区域中的分析物。
-
-
-
-
-
-
-
-
-