公开(公告)号：US09078985B2

公开(公告)日：2015-07-14

申请号：US13583606

申请日：2011-03-08

Applicant: Nicola Jeanne Maynard ,  Hugh D. Smyth

Inventor： Nicola Jeanne Maynard ,  Hugh D. Smyth

IPC: A61M11/00 ,  A61M15/00 ,  A61M16/00

CPC classification number: A61M15/0086 ,  A61M11/003 ,  A61M15/00 ,  A61M15/0006 ,  A61M15/0021 ,  A61M15/003 ,  A61M15/0035 ,  A61M15/009 ,  A61M2016/0015 ,  A61M2202/064 ,  A61M2205/0272 ,  A61M2205/8287 ,  A61M2206/16

Abstract: A dry powder delivery device may be configured to provide micronized dry powder particles to airways of a user. The device may include a cylindrical container delimiting a chamber containing at least one magnetically-responsive object, a motor external to said chamber, a magnet external to the chamber and rotatably coupled with the motor, and an outflow member configured to direct airflow to a user. The magnetically-responsive object may be coated with micronized dry powder particles, and the motor may be operable to rotate the magnet about an axis. Rotation of the magnet creates a magnetic field that causes the magnetically-responsive object to move in response to the magnetic field and collide with a side wall of the container to deaggregate the dry powder particles and aerosolize the dry powder in the chamber.

Abstract translation: 干粉递送装置可以被配置为向使用者的气道提供微粉化的干粉颗粒。 该装置可以包括限定容纳至少一个磁响应物体的腔室的圆柱形容器，在该腔室外部的电动机，该腔室外部的磁体并与该电动机可旋转地联接;以及流出部件，其将气流引导至使用者 。 磁性响应物体可以涂覆有微粉化的干粉末颗粒，并且电动机可操作以使磁体围绕轴旋转。 磁体的旋转产生磁场，使得响应于磁场的磁响应物体移动并与容器的侧壁碰撞，以使干粉颗粒解聚并使空腔中的干粉雾化。

公开(公告)号：US09074976B2

公开(公告)日：2015-07-07

申请号：US13385671

申请日：2012-02-29

Applicant: Natalie L. Adolphi ,  Edward R. Flynn ,  Howard Bryant ,  Kimberly Butler

Inventor： Natalie L. Adolphi ,  Edward R. Flynn ,  Howard Bryant ,  Kimberly Butler

IPC: G01N11/12 ,  B82Y15/00 ,  G01N11/00

CPC classification number: G01N11/12 ,  B82Y15/00 ,  G01N2011/0086

Abstract: A method for measuring the average viscosity of a test fluid uses calibrated magnetic nanoparticles, with certain chosen hydrodynamic diameters and actual lateral dimensions (e.g. diameters), that are mixed into a small volume of the test fluid and a single magnetic relaxation curve measurement to provide data for viscosity determination. The distribution of hydrodynamic particle sizes of an ensemble of magnetic nanoparticles that are magnetically blocked at room temperature can be determined. Modifications of the method can be used to determine the distribution of viscosities in a complex fluid at the sub-microscopic level providing a novel type of viscosity measurement.

公开(公告)号：US20150180046A1

公开(公告)日：2015-06-25

申请号：US14407997

申请日：2013-03-15

Applicant: STC. UNM

Inventor： Alexey Serov ,  Nalin Andersen ,  Plamen B Atanassov

IPC: H01M4/90 ,  C01G51/04 ,  C01G25/02 ,  C01G53/00 ,  C01G31/02 ,  C01G19/00 ,  C01G49/00 ,  C01G41/02 ,  C01G51/00 ,  C01G15/00

CPC classification number: H01M4/9016 ,  B01J21/066 ,  B01J23/005 ,  B01J23/08 ,  B01J23/10 ,  B01J23/14 ,  B01J23/18 ,  B01J23/20 ,  B01J23/30 ,  B01J23/75 ,  B01J23/83 ,  B01J23/8476 ,  B01J25/00 ,  B01J35/0033 ,  B01J37/0018 ,  B01J37/06 ,  C01G15/00 ,  C01G19/006 ,  C01G25/02 ,  C01G31/02 ,  C01G41/02 ,  C01G49/0054 ,  C01G51/04 ,  C01G51/40 ,  C01G53/40 ,  C01P2006/40

Abstract: A porous metal-oxide composite particle suitable for use as a oxygen reduction reaction or oxygen evolution reaction catalyst and sacrificial support based methods for making the same.

Abstract translation: 适合用作氧还原反应或氧气析出反应催化剂的多孔金属氧化物复合颗粒和用于制造其的基于牺牲支撑的方法。

公开(公告)号：US09040435B2

公开(公告)日：2015-05-26

申请号：US13121166

申请日：2009-06-30

Applicant: David J. Kissel ,  Charles Jeffrey Brinker

Inventor： David J. Kissel ,  Charles Jeffrey Brinker

IPC: C09D7/12 ,  C09D5/14 ,  C09D5/16 ,  C09D183/02 ,  C08K3/36 ,  C08K7/26 ,  C08K9/06

CPC classification number: C09D183/02 ,  C08K3/36 ,  C08K7/26 ,  C08K9/06 ,  C09D5/14 ,  C09D5/1687 ,  C09D7/62 ,  C09K3/18 ,  Y10T428/24975 ,  Y10T428/249953 ,  Y10T428/249981 ,  Y10T428/249986 ,  Y10T428/24999 ,  Y10T428/249991 ,  Y10T442/20 ,  Y10T442/218 ,  Y10T442/2279 ,  Y10T442/2525 ,  Y10T442/259

Abstract: Provided are superhydrophobic coatings, devices and articles including superhydrophobic coatings, and methods for preparing the superhydrophobic coatings. The exemplary superhydrophobic device can include a substrate component and one or more superhydrophobic coatings disposed over the substrate component, wherein at least one of the one or more superhydrophobic coatings has a water contact angle of at least about 150° and a contact angle hysteresis of less than about 1°. The one or more superhydrophobic coatings can include an ultra high water content acid catalyzed polysilicate gel, the polysilicate gel including a three dimensional network of silica particles having surface functional groups derivatized with a silylating agent and a plurality of pores.

Abstract translation: 提供的是超疏水涂层，包括超疏水涂层的装置和制品以及制备超疏水涂层的方法。 示例性超疏水装置可以包括底物组分和设置在基底组分上的一个或多个超疏水涂层，其中一个或多个超疏水涂层中的至少一个具有至少约150°的水接触角和较小的接触角滞后 大约1°。 一个或多个超疏水涂层可以包括超高含水酸催化的聚硅酸盐凝胶，所述聚硅酸盐凝胶包括具有由甲硅烷基化剂衍生的表面官能团和多个孔的二氧化硅颗粒的三维网络。

公开(公告)号：US20150133291A1

公开(公告)日：2015-05-14

申请号：US14400232

申请日：2013-03-15

Applicant: Abhaya Datye ,  Hien Pham

Inventor： Abhaya Datye ,  Hien Pham

IPC: B01J37/08 ,  B01J37/02 ,  B01J23/44

CPC classification number: B01J37/084 ,  B01J23/44 ,  B01J35/0013 ,  B01J35/002 ,  B01J35/006 ,  B01J35/0086 ,  B01J35/1019 ,  B01J35/1023 ,  B01J35/1038 ,  B01J35/1061 ,  B01J37/0203 ,  B01J37/0219

Abstract: Catalyst support materials that are coated with a thin carbon over-layer and methods for making the same are shown and described. In general, a supporting oxide material, which may or may not have a catalytic material already deposited on the surface, is coated with a thin carbon layer.

Abstract translation: 显示和描述涂覆有薄碳层的催化剂载体材料及其制备方法。 通常，可以或可以不具有已经沉积在表面上的催化材料的支撑氧化物材料被涂覆有薄碳层。

公开(公告)号：US20150093686A1

公开(公告)日：2015-04-02

申请号：US14381266

申请日：2013-03-11

Applicant: Alexey Serov ,  Ulises A Martinez ,  Plamen B Atanassov

Inventor： Alexey Serov ,  Ulises A Martinez ,  Plamen B Atanassov

IPC: H01M4/92 ,  H01M4/86

CPC classification number: H01M4/925 ,  B01J23/40 ,  B01J23/56 ,  B01J23/62 ,  B01J23/626 ,  B01J23/6525 ,  B01J23/8973 ,  B01J25/00 ,  B01J35/0013 ,  B01J35/0033 ,  B01J35/1061 ,  B01J37/0018 ,  B01J37/06 ,  B01J37/16 ,  B01J37/18 ,  B01J37/343 ,  B01J37/349 ,  H01M4/8605 ,  H01M4/8657 ,  H01M4/9016 ,  H01M4/92 ,  H01M4/921

Abstract: A method of preparing catalytic materials comprising depositing platinum or non-platinum group metals, or alloys thereof on a porous oxide support.

Abstract translation: 一种制备催化材料的方法，包括将铂或非铂族金属或其合金沉积在多孔氧化物载体上。

公开(公告)号：US08992984B1

公开(公告)日：2015-03-31

申请号：US12909572

申请日：2010-10-21

Applicant: C. Jeffrey Brinker ,  Carlee Erin Ashley ,  Xingmao Jiang ,  Juewen Liu ,  David S. Peabody ,  Walker Richard Wharton ,  Eric Carnes ,  Bryce Chackerian ,  Cheryl L. Willman

Inventor： C. Jeffrey Brinker ,  Carlee Erin Ashley ,  Xingmao Jiang ,  Juewen Liu ,  David S. Peabody ,  Walker Richard Wharton ,  Eric Carnes ,  Bryce Chackerian ,  Cheryl L. Willman

IPC: A61K9/14 ,  A61K9/51

CPC classification number: A61K9/127 ,  A61K9/1277 ,  A61K9/5115 ,  A61K9/5123 ,  A61K31/513 ,  A61K31/575 ,  A61K31/704 ,  A61K33/24 ,  A61K49/005

Abstract: Various embodiments provide materials and methods for synthesizing protocells for use in targeted delivery of cargo components to cancer cells. In one embodiment, the lipid bilayer can be fused to the porous particle core to form a protocell. The lipid bilayer can be modified with targeting ligands or other ligands to achieve targeted delivery of cargo components that are loaded within the protocell to a target cell, e.g., a type of cancer. Shielding materials can be conjugated to the surface of the lipid bilayer to reduce undesired non-specific binding.

Abstract translation: 各种实施方案提供用于合成原细胞以用于向癌细胞靶向递送货物组分的材料和方法。 在一个实施方案中，脂质双层可以与多孔颗粒核心融合以形成原细胞。 脂质双层可以用靶向配体或其他配体进行修饰，以实现载体在原细胞内的货物组分的靶向递送到靶细胞，例如一种类型的癌症。 屏蔽材料可以结合到脂质双层的表面以减少不期望的非特异性结合。

公开(公告)号：US08980730B1

公开(公告)日：2015-03-17

申请号：US13232629

申请日：2011-09-14

Applicant: Seung-Chang Lee ,  Steven R. J. Brueck

Inventor： Seung-Chang Lee ,  Steven R. J. Brueck

IPC: H01L21/20

CPC classification number: H01L21/02513 ,  C30B7/005 ,  C30B23/025 ,  C30B25/04 ,  C30B25/18 ,  C30B25/183 ,  C30B29/40 ,  C30B29/42 ,  H01L21/02381 ,  H01L21/02433 ,  H01L21/02455 ,  H01L21/02458 ,  H01L21/02505 ,  H01L21/02538 ,  H01L21/02546 ,  H01L21/02636 ,  H01L21/02642 ,  H01L21/02647 ,  H01L29/0665 ,  H01L29/0688 ,  H01L29/267

Abstract: Exemplary embodiments provide materials and methods of forming high-quality semiconductor devices using lattice-mismatched materials. In one embodiment, a composite film including one or more substantially-single-particle-thick nanoparticle layers can be deposited over a substrate as a nanoscale selective growth mask for epitaxially growing lattice-mismatched materials over the substrate.

Abstract translation: 示例性实施例提供了使用晶格失配材料形成高质量半导体器件的材料和方法。 在一个实施方案中，包含一个或多个基本上单个颗粒的纳米颗粒层的复合膜可以沉积在衬底上作为纳米级选择性生长掩模，用于在衬底上外延生长晶格失配的材料。

公开(公告)号：US08921569B2

公开(公告)日：2014-12-30

申请号：US13760605

申请日：2013-02-06

Applicant: STC.UNM ,  Johns Hopkins University

Inventor： Graham Timmins ,  Sharon Master ,  Vojo P Deretic ,  William Bishai

IPC: C07D213/86 ,  A61K9/00 ,  C07D213/81 ,  C07D213/83 ,  A61K31/44 ,  A61K31/4409

CPC classification number: C07D213/81 ,  A61K9/0019 ,  A61K9/0073 ,  A61K31/44 ,  A61K31/4409 ,  C07D213/83 ,  C07D213/86

Abstract: The present invention relates to the use of isotopically labeled derivatives of isoniazid, ethionamide and related compounds as effective therapy for the treatment of mycobacterial diseases, including Mycobacterium tuberculosis.

Abstract translation: 本发明涉及异烟肼，乙硫异烟胺和相关化合物的同位素标记衍生物在治疗分枝杆菌疾病（包括结核分枝杆菌）中的有效疗法。

公开(公告)号：US08908724B1

公开(公告)日：2014-12-09

申请号：US13843332

申请日：2013-03-15

Applicant: Steven R. J. Brueck ,  Xiang He ,  Steve Benoit

Inventor： Steven R. J. Brueck ,  Xiang He ,  Steve Benoit

IPC: H01S3/10 ,  G02B27/09 ,  H01S5/06

CPC classification number: H01S3/1022 ,  H01S3/08009 ,  H01S5/041 ,  H01S5/1212 ,  H01S5/1231 ,  H01S5/125 ,  H01S5/3235 ,  H01S5/3422 ,  H01S5/34313

Abstract: In some aspects of the present application, an apparatus for producing an interference pattern on a photosensitive portion formed on a surface of a sample is disclosed. The apparatus can include an optical system for providing interference between two coherent spherical wavefronts impinging on a thin-film photosensitive material formed on a surface of a sample, wherein a plane of the surface normal of the sample is arranged at an angle with respect to a plane defined by center propagation vectors of the two coherent spherical wavefronts; and one or more actuating elements operable to actuate one or more optical elements in the optical system, the sample, or both the one or more optical elements and the sample in one or more degrees of freedom to control a relative magnitude of a longitudinal and a transverse chirp of the interference pattern.

Abstract translation: 在本申请的一些方面，公开了一种用于在形成在样品表面上的感光部分上产生干涉图案的装置。 该装置可以包括光学系统，用于提供入射到形成在样品表面上的薄膜感光材料上的两个相干球面波前的干涉，其中样品的表面法线的平面相对于 由两个相干球面波前的中心传播矢量定义的平面; 以及一个或多个致动元件，其可操作以一个或多个自由度致动所述光学系统，所述样品或所述一个或多个光学元件和所述样品中的一个或多个光学元件，以控制纵向和纵向的相对幅度 横向啁啾的干涉图案。