公开(公告)号：US20040018121A1

公开(公告)日：2004-01-29

申请号：US10202453

申请日：2002-07-24

Inventor： James Shannon ,  Michael Ferriell ,  Hossain Saneii

IPC: B01J019/00

CPC classification number: B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00308 ,  B01J2219/00313 ,  B01J2219/00335 ,  B01J2219/00337 ,  B01J2219/00344 ,  B01J2219/00477 ,  B01J2219/00495 ,  B01J2219/00587 ,  B01J2219/00601 ,  B01J2219/00689 ,  B01J2219/00691 ,  B01J2219/0072 ,  B01J2219/00745 ,  B01J2219/00747 ,  C40B30/08 ,  C40B40/18 ,  C40B60/14

Abstract: A system for automated high-pressure synthesis and more particularly a high-pressure reactor assembly comprises a reaction block and a pressure manifold for the introduction of pressure to the reaction wells of a reaction block. The reactor includes one or more pressure resistant reaction wells or vessels disposed in the reaction block.

Abstract translation: 用于自动化高压合成的系统，更具体地说是高压反应器组件的系统包括用于向反应块的反应孔引入压力的反应块和压力歧管。 反应器包括设置在反应块中的一个或多个耐压反应井或容器。

公开(公告)号：US20040013565A1

公开(公告)日：2004-01-22

申请号：US10381588

申请日：2003-07-21

Inventor： Boris E Bosch ,  Thomas Riermeier ,  Uwe Dingerdissen ,  Gerhard Geiss ,  Norbert Stoll ,  Martin Krohn ,  Robert Lemke

IPC: B01J019/00

CPC classification number: B01J3/04 ,  B01J19/0046 ,  B01J2219/00162 ,  B01J2219/00306 ,  B01J2219/00351 ,  B01J2219/00389 ,  B01J2219/00477 ,  B01J2219/00484 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00601 ,  B01J2219/0068 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00745 ,  C40B40/18 ,  C40B60/14

Abstract: The invention relates to a scalable autoclave array for studying chemical reactions which consists of autoclave modules, which each consist of a reactor shell hermetically fastened over a reaction vessel and which can be filled with gas independently of one another via controllable autoclave valves from a pressure regulating chamber, which contains a pressure sensor and is connected via least one controllable valve to at least one gas supply and at least one gas outlet.

Abstract translation: 本发明涉及一种用于研究化学反应的可膨胀的高压灭菌器阵列，其由高压釜组件组成，每个高压釜组件由气密地紧固在反应容器上的反应器壳体组成，并且可以通过可控的高压灭菌阀从压力调节 室，其包含压力传感器，并且经由至少一个可控阀连接到至少一个气体供应源和至少一个气体出口。

公开(公告)号：US20030211024A1

公开(公告)日：2003-11-13

申请号：US10361911

申请日：2003-02-11

Inventor： David Lee Wojichowski

IPC: C01C001/08 ,  B01J019/00

CPC classification number: B01J4/002 ,  B01J8/082 ,  B01J19/126 ,  B01J2208/00415 ,  B01J2208/00442 ,  B01J2208/00548 ,  B01J2219/00123 ,  B01J2219/00135 ,  B01J2219/182 ,  C01C1/086 ,  F01N2610/12

Abstract: This invention relates to pollution control requirements for fossil fuel burning facilities, such as power plants, incinerators and cement kilns, and more particularity, to improved methods of generating ammonia from urea. Ammonia is the critical chemical additive used to reduce the emissions of nitrogen oxides from the combustion effluent by both selective non-catalytic reduction and selective catalytic reduction techniques.

Abstract translation: 本发明涉及化石燃料燃烧设施如发电厂，焚化炉和水泥窑的污染控制要求，更具体地涉及改进尿素生成氨的方法。 氨是用于通过选择性非催化还原和选择性催化还原技术减少来自燃烧流出物的氮氧化物排放的关键化学添加剂。

公开(公告)号：US20030198575A1

公开(公告)日：2003-10-23

申请号：US10321589

申请日：2002-12-18

Applicant: Hitachi, Ltd.

Inventor： Hideyuki Noda ,  Yoshinobu Kohara ,  Kazunori Okano

IPC: B01L003/00 ,  B01J019/00

CPC classification number: B01L3/021 ,  B01J19/0046 ,  B01J2219/00315 ,  B01J2219/00317 ,  B01J2219/00353 ,  B01J2219/00414 ,  B01J2219/00463 ,  B01J2219/00468 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00599 ,  B01J2219/00648 ,  B01J2219/00657 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00704 ,  B01J2219/00707 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01L3/502707 ,  B01L3/502761 ,  B01L2200/0657 ,  B01L2200/0668 ,  B01L2300/0838 ,  B01L2400/0487 ,  B01L2400/049 ,  G01N35/028 ,  G01N2035/00574 ,  Y10T436/119163 ,  Y10T436/2575

Abstract: There are provided a novel method and technology for arraying micro-particles. Micro-particle trapping capillaries each having an inner diameter smaller than the outer diameter of probe-immobilized micro-particles are prepared. By vacuuming the inside of each micro-particle trapping capillary, only one of the micro-particles is vacuumed onto an opening at the tip thereof and taken out from holders holding a plurality of the micro-particles. The micro-particle vacuumed onto the opening at the tip of each micro-particle trapping capillary is positioned at the opening of the capillary or the edge of each channel provided in a chip, the channels each having an inlet and an outlet with a slightly larger width than the outer diameter of the micro-particle so as to allow passage of only one micro-particle. The micro-particle vacuumed onto the opening at the capillary tip is injected into the capillary from the opening of the capillary or the channel edge of the chip.

Abstract translation: 提供了一种用于排列微粒子的新颖方法和技术。 制备各自具有小于探针固定的微粒外径的内径的微粒捕集毛细管。 通过抽吸每个微粒捕获毛细管的内部，只有一个微粒被抽吸到其尖端的开口上并从保持多个微粒的保持器中取出。 抽吸到每个微粒捕获毛细管尖端的开口处的微粒定位在毛细管的开口处或设置在芯片中的每个通道的边缘，每个通道具有入口和出口略大 宽度小于微粒的外径，以允许仅仅一个微粒通过。 被抽吸到毛细管尖端的开口上的微粒子从毛细管的开口或芯片的通道边缘注入毛细管中。

公开(公告)号：US20030156989A1

公开(公告)日：2003-08-21

申请号：US09873176

申请日：2001-06-01

Inventor： Adam Safir ,  Ralph Nielsen ,  Thomas H. McWaid ,  Richard Tiede ,  Lynn Van Erden

IPC: B01J019/00

CPC classification number: B01F7/167 ,  B01F7/00258 ,  B01F7/00266 ,  B01F7/00291 ,  B01F7/00416 ,  B01F7/00575 ,  B01F15/00207 ,  B01F2215/0037 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00308 ,  B01J2219/00335 ,  B01J2219/00337 ,  B01J2219/00342 ,  B01J2219/00353 ,  B01J2219/00373 ,  B01J2219/00389 ,  B01J2219/00418 ,  B01J2219/00477 ,  B01J2219/00481 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00601 ,  B01J2219/00689 ,  B01J2219/00698 ,  B01J2219/00722 ,  C40B40/14 ,  C40B60/14 ,  G01N35/1079

Abstract: Parallel semi-continuous or continuous reactors are disclosed. The parallel reactors preferably comprise four or more reaction vessels. The reaction vessels are preferably small volume reaction vessels, preferably pressure reaction vessels, and/or preferably integral with a common reactor block. The reaction vessels can comprise shaft-driven stirrers. At least two, preferably at least three or at least four liquid feed lines can provide selective fluid communication between each of the reaction vessels and one or more liquid reagent sources. Additional features, suitable in connection with parallel reactors or with single reaction vessels are also disclosed.

Abstract translation: 公开了平行半连续或连续反应器。 并联反应器优选包含四个或更多个反应容器。 反应容器优选为体积小的反应容器，优选为压力反应容器，和/或优选与普通反应器组合成一体。 反应容器可以包括轴驱动的搅拌器。 至少两个，优选至少三个或至少四个液体进料管线可以在每个反应容器和一个或多个液体试剂源之间提供选择性流体连通。 还公开了适用于并联反应器或单个反应容器的附加特征。

公开(公告)号：US20030152489A1

公开(公告)日：2003-08-14

申请号：US10344066

申请日：2003-02-06

Inventor： Rolf Gueller ,  Josef Schroer ,  Franz Metzger

IPC: B01J019/00

CPC classification number: G01N35/1097 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00308 ,  B01J2219/00335 ,  B01J2219/00337 ,  B01J2219/00342 ,  B01J2219/00346 ,  B01J2219/00373 ,  B01J2219/00376 ,  B01J2219/00405 ,  B01J2219/00407 ,  B01J2219/00414 ,  B01J2219/00418 ,  B01J2219/00585 ,  B01J2219/00601 ,  B01L3/502 ,  B01L3/50825 ,  B01L2300/049 ,  B01L2400/0644 ,  C40B60/14 ,  Y10T436/2575

Abstract: Twelve reaction vessels (2) in two parallel rows are attached to a switch block (401). The switch block (401) comprises a reaction block (403) and twelve slide plates (404), which are arranged within it and which can be adjusted between an open position, a closed position and a further position. In the open position, access in straight line to the associated reaction vessel (2) is possible whereas in the closed position, the corresponding reaction vessel (2) is closed in a pressure-tight manner by the switch block (401). In the case of a positive pressure or depression in the reaction vessel (2), the corresponding slide plate (404) is pressed by this positive pressure or depression against the reaction block (403) or is drawn onto it. By means of this switch block (401), it is also possible to carry out processes in which high positive pressures are present in the reaction vessels (2).

Abstract translation: 两个平行排列的12个反应容器（2）连接至开关块（401）。 开关块（401）包括反应块（403）和十二个滑动板（404），其布置在其内并且可以在打开位置，关闭位置和另一位置之间进行调节。 在打开位置，可以直接进入相关联的反应容器（2），而在关闭位置，相应的反应容器（2）通过开关块（401）以压力密闭的方式关闭。 在反应容器（2）中存在正压或低压的情况下，相应的滑板（404）通过该反应块（403）的正压力或压力被按压或被吸引到其上。 通过该开关块（401），也可以进行反应容器（2）中存在高正压的工序。

公开(公告)号：US20030133831A1

公开(公告)日：2003-07-17

申请号：US10354620

申请日：2003-01-30

Inventor： Christopher J. Knors ,  Yelena Tropsha ,  Noel G. Harvey ,  Richard P. Clarke

IPC: A61L009/00 ,  B01J019/00 ,  B01D011/04 ,  B01D011/02 ,  A61L002/00

CPC classification number: A61M25/00 ,  A61L2/16 ,  A61L29/16 ,  A61L2300/202 ,  A61L2300/404 ,  A61M2025/0056

Abstract: A method of impregnating a polymeric medical device with an antimicrobial agent is disclosed. The method involves forming a solution by dissolving triclosan in a compressed fluid and contacting the polymeric medical device with the solution. After the solution has been infused into the polymeric medical device, the solution and the medical device are separated.

Abstract translation: 公开了一种用抗菌剂浸渍聚合物医疗装置的方法。 该方法包括通过将三氯生溶解在压缩流体中并使聚合物医疗装置与溶液接触来形成溶液。 将溶液注入聚合物医疗装置之后，溶液和医疗装置分离。

公开(公告)号：US20030124025A1

公开(公告)日：2003-07-03

申请号：US10039804

申请日：2002-01-03

Inventor： Gary W. Mize ,  Brandy O. Mize

IPC: A61L009/00 ,  B01J019/00 ,  G01D011/26 ,  B01D011/04 ,  A61L002/00

CPC classification number: A62D3/38 ,  A61L2/18 ,  A61L2/22 ,  A62D2101/02

Abstract: A method and apparatus is provided to protect the mail carrier and mail recipient from exposure to mail contaminated with biological agents. A bio-safe device is user programmed and loaded with an inexpensive decontaminant to automatically perform a treatment cycle on deposited mail to eliminate anthrax and other infectious agents from within an enclosed mail receptacle. This provides the delivery mail carrier or an individual mail recipient the means to destroy infectious agents before physical contact with the mail.

Abstract translation: 提供了一种方法和装置，用于保护邮递员和邮件接收者免受生物制剂污染的邮件的暴露。 生物安全装置是用户编程的，并装载有廉价的去污剂，以自动执行存放邮件处理周期，以消除封闭邮件容器内的炭疽和其他感染因子。 这提供了递送邮件运营商或个人邮件接收者在与邮件进行身体接触之前销毁传染性物质的手段。

公开(公告)号：US20030087309A1

公开(公告)日：2003-05-08

申请号：US10229571

申请日：2002-08-27

Inventor： Shiping Chen

IPC: B01J019/00 ,  G01N033/48

CPC classification number: B01J19/0046 ,  B01J2219/00286 ,  B01J2219/00317 ,  B01J2219/00511 ,  B01J2219/00522 ,  B01J2219/00524 ,  B01J2219/00585 ,  B01J2219/00702 ,  B01J2219/0072 ,  B01J2219/0074 ,  B01L3/0262 ,  B01L3/5025 ,  B01L3/50857 ,  B01L2200/027 ,  B01L2200/0605 ,  B01L2200/0642 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2400/0688 ,  B01L2400/086 ,  C40B60/12

Abstract: Systems and methods involved in extreme high throughput screening of compounds which have an affinity for a biological target are disclosed. The system is based on a capillary bundle with two distinguishable ends wherein capillaries on one end are connected to compounds stored in discrete reservoirs and capillaries on the other end are bound and processed to form a two dimensional microarray. A capillary bundle having reaction wells for hybridization and compound reaction in one end of the capillaries is disclosed. Also disclosed are various methods of identifying a target compound in a liquid using this capillary bundle as well as methods of fabricating the bundle. A novel surface tension guided reaction chamber is also provided. Methods and chemistry for fabrication and use of a surface tension guided reaction chamber in binding and hybridization assays are also disclosed. Methods and systems for precise metering of fluids within the capillaries and at the reaction chambers, including the surface tension guided nullvirtualnull reaction well are provided.

Abstract translation: 公开了对生物靶标具有亲和性的化合物的极高通量筛选所涉及的系统和方法。 该系统基于毛细管束，其具有两个可区分的端部，其中一端的毛细管连接到存储在离散储器中的化合物，另一端的毛细血管被结合并加工以形成二维微阵列。 公开了一种毛细管束，其具有在毛细血管的一端中用于杂交和化合物反应的反应孔。 还公开了使用该毛细管束在液体中鉴定目标化合物的各种方法以及制造束的方法。 还提供了一种新颖的表面张力引导反应室。 还公开了在结合和杂交测定中制造和使用表面张力引导反应室的方法和化学。 提供了用于精确计量毛细管内和反应室内的流体的方法和系统，包括表面张力引导的“虚拟”反应井。

公开(公告)号：US20020176811A1

公开(公告)日：2002-11-28

申请号：US09923464

申请日：2001-08-06

Inventor： Konan Peck ,  Ji-Yen Cheng

IPC: B01J019/00

CPC classification number: B01J19/0046 ,  B01J2219/00274 ,  Y10T436/2575

Abstract: Apparatuses and methods are described for parallel oligonucleotide synthesis of hundreds of different sequences and lengths at a time. Standard phosphoramidite chemistry is employed. The syntheses take place in a reaction plate compatible with the industrial standard microplate format to allow the use of readily available automated instruments for subsequent processing. Key parameters in reducing synthesis volume in small reaction wells are discussed. This invention provides solutions to the difficulties of low volume, high number synthetic reactions.

Abstract translation: 描述了一次并行寡核苷酸合成数百种不同序列和长度的装置和方法。 使用标准亚磷酰胺化学。 合成在与工业标准微板格式兼容的反应板中进行，以允许使用容易获得的自动化仪器进行后续处理。 讨论了在小反应井中降低合成体积的关键参数。 本发明提供了低容量，高数量的合成反应的困难的解决方案。