公开(公告)号：US20180049698A1

公开(公告)日：2018-02-22

申请号：US15239838

申请日：2016-08-18

Applicant: Mad Apparel, Inc.

Inventor： James Artel Berg ,  Hamid Hameed Butt ,  Liang Yao ,  Gaston J. MacMillan ,  J.M. Hasitha B. Jayasundara

IPC: A61B5/00 ,  A61B5/0408 ,  A61B5/0492 ,  A41D31/02 ,  A41D1/00 ,  A41H43/04

CPC classification number: A61B5/6804 ,  A41D1/005 ,  A61B5/0408 ,  A61B5/0492 ,  A61B2562/0209 ,  A61B2562/125

Abstract: A garment can be manufactured by bonding an adhesive to a first layer of fabric and a second layer of fabric. Holes are cut into each layer of fabric to accommodate the integration of sensors and a processing unit mount. Conductive thread embroidered onto a support layer is bonded to the adhesive of the second layer of fabric. The support layer is removed such that the conductive thread remains bonded to the adhesive. The layers of fabric are bonded together such that the conductive thread is coupled between the two layers of adhesive. A back plate is added to the layers of fabric to provide structural support for the mount. The conductive thread is exposed within each hole, and the mount and sensors can be coupled within the holes such that an electrical connection is established between the mount and at least one sensor via the conductive thread.

公开(公告)号：US09883826B2

公开(公告)日：2018-02-06

申请号：US14413257

申请日：2013-07-15

Applicant: DIAGNOSTIC BIOCHIPS, INC.

Inventor： Brian Jamieson ,  Mary Emma Gorham Bigelow

IPC: A61B5/1473 ,  A61N1/36 ,  A61B5/00 ,  A61B5/145 ,  A61B5/0476 ,  A61B5/04 ,  A61N1/05 ,  B82Y15/00

CPC classification number: A61B5/14735 ,  A61B5/04001 ,  A61B5/0476 ,  A61B5/14546 ,  A61B5/4836 ,  A61B5/4845 ,  A61B5/4848 ,  A61B5/6852 ,  A61B5/6876 ,  A61B2562/028 ,  A61B2562/125 ,  A61N1/0529 ,  A61N1/0534 ,  A61N1/36139 ,  B82Y15/00

Abstract: Certain embodiments comprise an implantable probe for rapid measurement of multiple neurochemicals on the cellular scale in the brain. Rapid detection of multiple chemicals in vivo (animal or humans) may provide an improved understanding of acute changes in neurochemicals that occur over several seconds. The neurotransmitter chemical sensing platform may provide for continuous in vivo sensing in trials of psychoactive drugs in the laboratory animal market. The high spatial resolution of the probe may allow for chemical detection around small groups of neurons, which may help to isolate the endogenous activity of different neuron types due to disease states. Neurochemical detection may also be used to measure tissue response to exogenous stimuli, such as pharmacodynamics of drugs. The high temporal and spatial resolutions and multi-neurochemical sensing of the probe may allow for detailed studies on in vivo brain response to both endogenous and exogenous stimuli.

公开(公告)号：US09867979B2

公开(公告)日：2018-01-16

申请号：US15207199

申请日：2016-07-11

Applicant: ZYVEX LABS, LLC

Inventor： Rahul Saini ,  John Neal Randall

IPC: A61N1/05 ,  A61B5/04 ,  B81B3/00 ,  A61B5/00 ,  A61B5/0492 ,  A61B5/0496

CPC classification number: A61N1/0543 ,  A61B5/04001 ,  A61B5/0492 ,  A61B5/0496 ,  A61B5/6846 ,  A61B2562/0209 ,  A61B2562/046 ,  A61B2562/125 ,  A61B2562/166 ,  A61N1/05 ,  B81B3/0089 ,  B81B2203/04 ,  Y10T29/49117

Abstract: A multi-electrode array with individually isolated electrodes each configurable for a target-containing carrier and a method for fabricating the array are disclosed. In an exemplary embodiment, the array includes a substrate; and a plurality of electrodes disposed on the substrate. Each electrode of the plurality of electrodes has a conductive tip-end and an insulated remainder. A first electrode of the plurality of electrodes has a first configuration selected to bring a conductive tip end of the first electrode in proximity to a first target structure, and a second electrode of the plurality of electrodes has a second configuration selected to bring a conductive tip end of the second electrode in proximity to a second target structure. The first configuration and the second configuration are different. A first contact of the plurality of contacts may be electrically coupled to the first electrode through the substrate.

公开(公告)号：US09867571B2

公开(公告)日：2018-01-16

申请号：US15102205

申请日：2015-01-06

Applicant: INTERAXON INC.

Inventor： Christopher Allen Aimone ,  Trevor Coleman ,  Ariel Stephanie Garten ,  Samuel Thomas MacKenzie

IPC: A61B5/0478 ,  A61B5/00

CPC classification number: A61B5/6803 ,  A61B5/0478 ,  A61B5/6814 ,  A61B5/6831 ,  A61B5/7203 ,  A61B2562/0209 ,  A61B2562/0215 ,  A61B2562/125 ,  A61B2562/164 ,  A61B2562/166

Abstract: A wearable apparatus for wearing on a head of a user, the apparatus has a band assembly comprising an outer band member comprising outer band ends joined by a curved outer band portion of a curve generally shaped to correspond to the user's forehead; a flexible inner band member comprising inner band ends joined by a curved inner band portion of a curve generally shaped to correspond to the user's forehead, the inner band member is attached to the outer band member at least by each inner band end respectively attached to a respective one of the outer band ends; at least one brainwave sensor disposed inwardly along the curved inner band portion to provide a flexible conductive surface; and a deformable attachment that connects the flexible inner band member to the outer band, the deformable attachment allowing the inner band to conform to the user's forehead shape, the deformable attachment having a biasing component to urge the at the at least one brainwave sensor towards the user's forehead when worn by the user.

公开(公告)号：US09848795B2

公开(公告)日：2017-12-26

申请号：US14723408

申请日：2015-05-27

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Andrew T. Marecki ,  Paul Hultz ,  Michael C. Kozlowski ,  Brian Stewart

IPC: A61B5/042 ,  A61B18/14 ,  A61B5/00 ,  A61B17/00 ,  A61B18/00

CPC classification number: A61B5/0422 ,  A61B5/6855 ,  A61B5/6856 ,  A61B5/6857 ,  A61B5/6858 ,  A61B5/6859 ,  A61B18/1492 ,  A61B2017/00044 ,  A61B2018/0016 ,  A61B2018/00267 ,  A61B2562/0209 ,  A61B2562/125 ,  A61B2562/164 ,  A61B2562/166 ,  Y10T29/49119 ,  Y10T29/49126

Abstract: An expandable electrode assembly for use in a cardiac mapping procedure includes multiple bipolar electrode pairs including a first electrode located on an outer surface and a second electrode located on an inner surface of the individual splines forming the expandable electrode assembly. Such an electrode arrangement may produce improved electrical activation signals which may be used to produce a more accurate map of the electrical activity of a patient's heart.

公开(公告)号：US09801574B2

公开(公告)日：2017-10-31

申请号：US14875539

申请日：2015-10-05

Applicant: DexCom, Inc.

Inventor： Mark A. Tapsak ,  Rathbun K. Rhodes ,  Mark C. Shults ,  Jason D. McClure

IPC: A61B5/05 ,  A61B5/1486 ,  C12Q1/00 ,  A61L31/12 ,  B01D69/14 ,  B01D71/54 ,  B01D71/80 ,  A61B5/145 ,  A61B5/1473 ,  B05D3/00 ,  B05D5/00

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/1486 ,  A61B2562/028 ,  A61B2562/125 ,  A61L31/12 ,  B01D69/141 ,  B01D71/54 ,  B01D71/80 ,  B05D3/007 ,  B05D5/00 ,  C12Q1/002 ,  C12Q1/006 ,  Y10T428/31551

Abstract: The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

公开(公告)号：US20170290546A1

公开(公告)日：2017-10-12

申请号：US15478110

申请日：2017-04-03

Applicant: MEDTRONIC MINIMED, INC.

Inventor： David C. Antonio ,  Eric Allan Larson ,  Jose J. Ruelas ,  Sukhjeet S. Ranauta

IPC: A61B5/00 ,  A61B5/1473 ,  A61B17/34 ,  A61B5/145

CPC classification number: A61B5/6849 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/6833 ,  A61B5/742 ,  A61B5/746 ,  A61B17/3468 ,  A61B2560/0219 ,  A61B2560/0406 ,  A61B2560/0412 ,  A61B2560/045 ,  A61B2560/0468 ,  A61B2560/063 ,  A61B2562/125 ,  A61B2562/166 ,  A61B2562/227

Abstract: A simple, disposable sensing device for sensing an analyte is housed in a single case. The sensing device can transmit sensor data to monitoring device(s). The sensing device includes: a case having a lower major wall adapted to be mounted against a patient's skin, and an upper opposing major wall; a sensor extending from the case and having a distal end sensitive to the analyte to produce an electrical signal, and a proximal end within the case having electrical contacts; a printed circuit board assembly within the case supported by one of the major walls to receive the electrical signal via the electrical contacts; and an elastomeric pad disposed in the case and biased by the other major wall to urge the proximal end of the sensor into contact with the printed circuit board assembly and maintain an electrical connection between the electrical contacts and the printed circuit board assembly.

公开(公告)号：US20170290534A1

公开(公告)日：2017-10-12

申请号：US15478092

申请日：2017-04-03

Applicant: MEDTRONIC MINIMED, INC.

Inventor： David C. Antonio ,  Eric Allan Larson ,  Jose J. Ruelas ,  Akhil Srinivasan

IPC: A61B5/145 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/002 ,  A61B5/0022 ,  A61B5/14865 ,  A61B5/6832 ,  A61B2560/0425 ,  A61B2560/045 ,  A61B2560/063 ,  A61B2562/125 ,  A61B2562/227

Abstract: A medical sensor device includes a sensor assembly including an underside surface for attachment against a patient's skin, a sensor portion to detect a characteristic of the patient, and sensor assembly contacts which in operation carry signals representing the detected characteristic. The device also includes a transmitter assembly removably engageable with the sensor assembly and including circuitry to take the signals from the sensor assembly contacts and to transmit readings of the detected characteristic to external equipment. The device also includes mechanical interface components on the sensor assembly and the transmitter assembly which allow the transmitter assembly to be brought into abutment with the sensor assembly at a first angular position via relative axial movement between them, and then allow a relative rotation of the assemblies with respect to one another towards a second angular position and presents axial separation of the assemblies in the second angular position.

公开(公告)号：US09782095B2

公开(公告)日：2017-10-10

申请号：US13328035

申请日：2011-12-16

Applicant: Antti Kustaa Antipas Ylostalo ,  Juha Petri Virtanen

Inventor： Antti Kustaa Antipas Ylostalo ,  Juha Petri Virtanen

IPC: A61B5/04 ,  A61B5/0408 ,  A61B5/00 ,  A61B5/0478 ,  A61B5/0492

CPC classification number: A61B5/0408 ,  A61B5/0006 ,  A61B5/04087 ,  A61B5/0478 ,  A61B5/0492 ,  A61B5/6833 ,  A61B2560/0412 ,  A61B2562/0215 ,  A61B2562/0217 ,  A61B2562/125 ,  A61B2562/164

Abstract: A disposable self-powered biomedical sensor comprises a printed wet electrode on a substrate sheet. The wet electrode is provided with an electrolyte element to enhance the electrical contact with a surface to be measured. Moreover, a printed battery encapsulated in a hermetically sealed compartment is provided on the substrate sheet. The disposable self-powered sensor can be stored within an enclosure or a package which provides a proper atmosphere to prevent the drying of the electrolyte and prolong the shelf life of the sensors.

公开(公告)号：US20170265788A1

公开(公告)日：2017-09-21

申请号：US15310253

申请日：2015-05-11

Applicant: President and Fellows of Harvard College

Inventor： Qimin Quan ,  Wooyoung Hong ,  Marko Loncar

IPC: A61B5/1459 ,  G01N21/552 ,  G01N21/64 ,  G01N21/65 ,  G01H9/00 ,  G01N33/543 ,  G01N33/53 ,  A61B5/1455 ,  A61B5/1473 ,  A61B5/145 ,  A61B5/01 ,  A61B5/05 ,  B82B1/00 ,  B82B3/00 ,  G01N15/14

CPC classification number: A61B5/1459 ,  A61B5/01 ,  A61B5/05 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/14556 ,  A61B5/14735 ,  A61B2562/0238 ,  A61B2562/028 ,  A61B2562/0285 ,  A61B2562/029 ,  A61B2562/125 ,  B82B1/001 ,  B82B3/0019 ,  G01H9/00 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1484 ,  G01N21/553 ,  G01N21/6428 ,  G01N21/65 ,  G01N33/5308 ,  G01N33/54373 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2201/08

Abstract: The present invention generally relates, in some aspects, to systems and methods for making and using sensors or other devices, such as optical components. One aspect is generally directed to a sensor or other device comprising a nanometer-sized portion. In some embodiments, the sensor can be used to determine various characteristics such as temperature, humidity, an electric field, a magnetic field, an analyte, or the like. For instance, in one embodiment, a portion of a sensor device may be inserted into a cell and used to study the cell, e.g., using optical techniques such as surface plasma resonance. In some embodiments, such sensors or other devices may comprise metal, glass, or other materials, which can be prepared using etching or other techniques.