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    MICROFLUIDIC DEVICE USING MICROFLUIDIC CHIP AND MICROFLUIDIC DEVICE USING BIOMOLECULE MICROARRAY CHIP
    81.
    发明申请
    MICROFLUIDIC DEVICE USING MICROFLUIDIC CHIP AND MICROFLUIDIC DEVICE USING BIOMOLECULE MICROARRAY CHIP 有权
    使用生物分子微量芯片的微流控芯片和微流化器件的微流体装置

    公开(公告)号：US20110257037A1

    公开(公告)日：2011-10-20

    申请号：US13168298

    申请日：2011-06-24

    申请人： Beom-seok LEE ,  Jeong-gun Lee ,  Jong-myeon Park ,  Yoon-kyoung Cho

    发明人： Beom-seok LEE ,  Jeong-gun Lee ,  Jong-myeon Park ,  Yoon-kyoung Cho

    IPC分类号： C40B40/00 ,  C40B40/10 ,  C40B40/02 ,  C40B40/06

    CPC分类号： B01L3/502738 ,  B01L3/502707 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/025 ,  B01L2200/0621 ,  B01L2200/16 ,  B01L2300/04 ,  B01L2300/0636 ,  B01L2300/0806 ,  B01L2400/0409 ,  B01L2400/0677 ,  Y10T436/15

    摘要： Disclosed is a microfluidic device including a microfluidic structure formed in a platform in which various examinations, such as an immune serum examination, can be automatically performed using the biomolecule microarray chip. The biomolecule microarray chip-type microfluidic device using a biomolecule microarray chip comprises: a platform which is rotatable; a microfluidic structure disposed in the platform, comprising: a plurality of chambers; a plurality of channels connecting the chambers each other; and a plurality of valves controlling flow of fluids through the channels, wherein the microfluidic structure controls flow of a fluid sample using rotation of the platform and the valves; and a biomolecule microarray chip mounted in the platform such that biomolecule capture probes bound to the biomolecule microarray chip contact the fluid sample in the microfluidic structure.

    摘要翻译： 公开了一种微流体装置，其包括在平台中形成的微流体结构，其中可以使用生物分子微阵列芯片自动执行各种检查，例如免疫血清检查。 使用生物分子微阵列芯片的生物分子微阵列芯片型微流器件包括：可旋转的平台; 设置在平台中的微流体结构，包括：多个室; 连接所述室的多个通道; 以及多个阀，其控制通过所述通道的流体流动，其中所述微流体结构通过所述平台和所述阀的旋转来控制流体样品的流动; 以及安装在平台中的生物分子微阵列芯片，使得与生物分子微阵列芯片结合的生物分子捕获探针与微流体结构中的流体样品接触。

    Microfluidic valve, method of manufacturing the same, and microfluidic device comprising the microfluidic valve
    83.
    发明授权
    Microfluidic valve, method of manufacturing the same, and microfluidic device comprising the microfluidic valve 有权
    微流控阀，其制造方法以及包含微流体阀的微流体装置

    公开(公告)号：US07980272B2

    公开(公告)日：2011-07-19

    申请号：US12133396

    申请日：2008-06-05

    申请人： Jong-myeon Park ,  Yoon-kyoung Cho ,  Beom-seok Lee ,  Jeong-gun Lee

    发明人： Jong-myeon Park ,  Yoon-kyoung Cho ,  Beom-seok Lee ,  Jeong-gun Lee

    IPC分类号： F15C1/04

    CPC分类号： F16K99/0001 ,  F16K99/0032 ,  F16K99/004 ,  F16K2099/0084 ,  Y10T29/49412 ,  Y10T137/2191 ,  Y10T137/2196

    摘要： Provided is a microfluidic valve, a method of manufacturing the microfluidic valve, and a microfluidic device that employs the microfluidic valve. The microfluidic valve includes a platform that includes two substrates combined facing each other; a channel having a first depth allowing a fluid to flow between the two substrates; a valve gap that is disposed on at least a region of the channel and has a second depth which is smaller than the first depth; and a valve plug that is disposed to fill the valve gap and is formed of a valve material made by mixing a phase change material, which is solid at room temperature, with a plurality of exothermic particles that emit an amount of heat sufficient to melt the phase change material by absorbing electromagnetic waves.

    摘要翻译： 本发明提供一种微流体阀，微流体阀的制造方法和采用该微流体阀的微流体装置。 该微流体阀包括一个平台，该平台包括彼此相结合的两个基板; 具有允许流体在两个基板之间流动的第一深度的通道; 阀间隙，其设置在所述通道的至少一个区域上，并且具有小于所述第一深度的第二深度; 以及阀塞，其设置成填充阀间隙，并且由阀室材料形成，所述阀门材料是通过将在室温下为固体的相变材料与多个放出足以熔化的 相变材料吸收电磁波。

    Biochemical analyzer and method of controlling internal temperature of the biochemical analyzer
    84.
    发明授权
    Biochemical analyzer and method of controlling internal temperature of the biochemical analyzer 有权
    生化分析仪和生化分析仪内部温度控制方法

    公开(公告)号：US07943088B2

    公开(公告)日：2011-05-17

    申请号：US11972708

    申请日：2008-01-11

    申请人： Jeong-gun Lee ,  Yong-moo Shin ,  Kui-hyun Kim ,  Jin-han Chung

    发明人： Jeong-gun Lee ,  Yong-moo Shin ,  Kui-hyun Kim ,  Jin-han Chung

    IPC分类号： C12Q1/68 ,  G01N15/06

    CPC分类号： B01L7/52 ,  B01L3/5027 ,  B01L9/527 ,  B01L2300/0681 ,  B01L2300/0806 ,  B01L2300/1822 ,  B01L2300/1827 ,  B01L2300/1844 ,  B01L2300/1883 ,  B01L2400/0409 ,  G01N35/00069 ,  G01N2035/00346 ,  Y10T436/11 ,  Y10T436/25

    摘要： Provided is a biochemical analyzer in which a microfluidic biochemical assay may be performed. The analyzer includes: a microfluidic device loading space including a microfluidic device supporting unit detachably supporting a microfluidic device including an energy application region in which an energy is applied; an energy source loading space including an energy source applying the energy to the radiation application region; and an isolation wall isolating the microfluidic device loading space and the energy source loading space to prevent heat transfer between the microfluidic device loading space and the energy source loading space and including a window through which the energy can be transmitted. A method of controlling an internal temperature of the biochemical analyzer is also provided.

    摘要翻译： 提供了可以进行微流体生化测定的生化分析仪。 该分析仪包括：微流体装置装载空间，其包括微流体装置支撑单元，其可拆卸地支撑包括其中施加能量的能量施加区域的微流体装置; 能量源装载空间，其包括将能量施加到所述辐射施加区域的能量源; 隔离壁隔离微流体装置加载空间和能量源装载空间，以防止微流体装置加载空间与能量源装载空间之间的热传递并且包括能够传输能量的窗口。 还提供了一种控制生化分析仪内部温度的方法。

    Quantitative cell dispensing apparatus using liquid drop manipulation
    85.
    发明授权
    Quantitative cell dispensing apparatus using liquid drop manipulation 有权
    使用液滴操作的定量细胞分配装置

    公开(公告)号：US07901633B2

    公开(公告)日：2011-03-08

    申请号：US11491825

    申请日：2006-07-24

    申请人： Nam Huh ,  Jeong-gun Lee

    发明人： Nam Huh ,  Jeong-gun Lee

    IPC分类号： B01L3/02 ,  G01N1/10

    CPC分类号： B01L3/0241 ,  B01L2200/0647 ,  B01L2200/0673 ,  B01L2200/143 ,  B01L2300/0819 ,  B01L2300/089 ,  B01L2400/027 ,  B01L2400/0427 ,  G01N2035/00237 ,  Y10T436/2575

    摘要： Provided is a quantitative cell dispensing apparatus using liquid droplet manipulation, for quantitatively dispensing cells from hydrophilic suspension containing a plurality of cells. The quantitative cell dispensing apparatus includes hydrophilic suspension, a liquid droplet manipulation unit, a dispensing unit, a sensing unit, and a control unit. The hydrophilic suspension includes a plurality of cells and electrolyte, and the liquid droplet manipulation unit. The liquid droplet manipulation unit includes an inlet and a liquid droplet outlet portion. The dispensing unit discharges a liquid droplet received from the liquid droplet outlet portion to a target portion. The sensing unit optically senses liquid droplets distributed on a panel of the liquid droplet manipulation unit. The control unit analyses the number of cells contained in each liquid droplet using a single sensed by the sensing unit, and controls the liquid droplet manipulation unit to transfer a liquid droplet containing a predetermined number of cells to the liquid droplet outlet portion.

    摘要翻译： 提供了一种使用液滴操作的定量细胞分配装置，用于从含有多个细胞的亲水性悬浮液定量分配细胞。 定量细胞分配装置包括亲水性悬浮液，液滴操作单元，分配单元，感测单元和控制单元。 亲水性悬浮液包括多个细胞和电解质，以及液滴操作单元。 液滴操作单元包括入口和液滴出口部分。 分配单元将从液滴出口部分接收的液滴排放到目标部分。 感测单元光学地感测分布在液滴操作单元的面板上的液滴。 控制单元使用感测单元检测到的单个分析每个液滴中包含的细胞的数量，并且控制液滴操作单元将含有预定数量的细胞的液滴转移到液滴出口部分。

    Droplet printing apparatus using capillary electric charge concentration
    86.
    发明授权
    Droplet printing apparatus using capillary electric charge concentration 有权
    液滴打印装置采用毛细管电荷浓度

    公开(公告)号：US07794054B2

    公开(公告)日：2010-09-14

    申请号：US11746299

    申请日：2007-05-09

    申请人： Beom-seok Lee ,  Jeong-gun Lee ,  In-seok Kang ,  Jin-seok Hong ,  Dustin Moon

    发明人： Beom-seok Lee ,  Jeong-gun Lee ,  In-seok Kang ,  Jin-seok Hong ,  Dustin Moon

    IPC分类号： B41J2/06

    CPC分类号： B41J2/06

    摘要： A droplet printing apparatus using capillary electric charge concentration includes a reservoir which contains a solution, a capillary nozzle comprising a back-end part and a front-end part disposed substantially opposite the back-end part, a target member spaced apart from the front-end part of the capillary nozzle at a predetermined distance, and a voltage supplier which supplies a voltage to the solution, wherein the back-end part is immersed in the solution and transmits the solution to the front-end part.

    摘要翻译： 使用毛细管电荷浓度的液滴印刷装置包括：包含溶液的储存器，包括后端部分的毛细管喷嘴和基本上与后端部分相对设置的前端部分，与前端部分间隔开的目标部件， 在预定距离的毛细管喷嘴的端部，以及向溶液提供电压的电压供给器，其中后端部分浸入溶液中并将溶液传输到前端部分。

    Optical detection apparatus, optical detection method, and microfluidic system including the optical detection apparatus
    87.
    发明授权
    Optical detection apparatus, optical detection method, and microfluidic system including the optical detection apparatus 有权
    光学检测装置，光学检测方法和包括光学检测装置的微流体系统

    公开(公告)号：US07692794B2

    公开(公告)日：2010-04-06

    申请号：US11972266

    申请日：2008-01-10

    申请人： Su-hyeon Kim ,  Jeong-gun Lee

    发明人： Su-hyeon Kim ,  Jeong-gun Lee

    IPC分类号： G01N21/25

    CPC分类号： G01N21/07 ,  G01N21/253 ,  G01N21/276 ,  G01N21/314

    摘要： Provided are an optical detection apparatus, a microfluidic system including the same, and an optical detection method. The optical detection apparatus including: at least one light emission unit which emits light of a predetermined wavelength band; at least one light receiving unit which is disposed such that the light receiving unit receives the light emitted from the light emission unit and generates an electrical signal according to the intensity of the light received, wherein the number of light receiving units is the same as the number of light emission units; a rotation operating unit which rotates a disk-type microfluidic apparatus comprising at least one detection chamber in which a sample is to be loaded such that the detection chamber is disposed in a light pathway between the light emission unit and the light receiving unit; and a processor which measures a property of the sample contained in the detection chamber using the electrical signal generated by the light receiving unit.

    摘要翻译： 提供了一种光学检测装置，包括该光学检测装置的微流体系统和光学检测方法。 所述光学检测装置包括：发射预定波长带的光的至少一个发光单元; 至少一个光接收单元，其设置成使得所述光接收单元接收从所述发光单元发射的光并根据所接收的光的强度产生电信号，其中所述光接收单元的数量与 发光单位数量; 旋转操作单元，其旋转盘式微流体装置，其包括至少一个检测室，其中样品将被装载，使得所述检测室设置在所述发光单元和所述光接收单元之间的光路径中; 以及处理器，其使用由光接收单元生成的电信号来测量包含在检测室中的样品的性质。

    PUMP UNIT AND CENTRIFUGAL MICROFLUIDIC SYSTEM HAVING THE SAME
    89.
    发明申请
    PUMP UNIT AND CENTRIFUGAL MICROFLUIDIC SYSTEM HAVING THE SAME 审中-公开
    泵单元和离心微流体系统

    公开(公告)号：US20080226504A1

    公开(公告)日：2008-09-18

    申请号：US11861324

    申请日：2007-09-26

    申请人： Jong-myeon PARK ,  Nam Huh ,  Jeong-gun Lee ,  Kyu-youn Hwang

    发明人： Jong-myeon PARK ,  Nam Huh ,  Jeong-gun Lee ,  Kyu-youn Hwang

    IPC分类号： B04B5/10

    CPC分类号： B01L3/50273 ,  B01L3/502738 ,  B01L2300/0803 ,  B01L2400/0442 ,  B01L2400/0487 ,  B01L2400/0677 ,  F04B19/006 ,  F04B19/24 ,  F04F1/06

    摘要： Provided are a pump unit and a centrifugal microfluidic system including the pump unit. The pump unit includes a gas generating agent. The gas generating agent includes a plurality of heating particles generating heat by absorbing energy and one of a sublimation material, azide, and azo compound mixed with the heating particles. When energy is supplied to the gas generating agent, the gas generating agent generates gas due to heat emitted from the heating particles to increase an air pressure around the gas generation agent so that the fluid is moved by the increased air pressure.

    摘要翻译： 提供了包括泵单元的泵单元和离心微流体系统。 泵单元包括气体发生剂。 气体发生剂包括通过吸收能量产生热的多个加热颗粒和与加热颗粒混合的升华材料，叠氮化物和偶氮化合物之一。 当向气体发生剂供应能量时，气体发生剂由加热颗粒发出的热量产生气体，从而增加气体发生剂周围的空气压力，使得流体通过增加空气压力而移动。